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公开(公告)号:WO2022169710A1
公开(公告)日:2022-08-11
申请号:PCT/US2022/014555
申请日:2022-01-31
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor: RAYMOND, Timothy M. , MACKINNON, Peter , JACKSON, Michael R.
Abstract: Described is a solvent manager for a liquid chromatography system. The solvent manager includes a temperature control module, a plurality of solvent reservoirs, a gradient proportioning valve and a degasser. The temperature control module maintains a substantially constant temperature of one or more of the plurality of solvent reservoirs, gradient proportioning valve and degasser. The temperature control module may include a thermal chamber having an enclosure with a thermally controlled internal environment and may also include an active thermal element such as one or more heaters. The enclosure may surround at least one of the plurality of solvent reservoirs, gradient proportioning valve and degasser. The temperature control module reduces the negative effects on solvent composition that result from temperature-dependent changes in solvent viscosities and solvent densities. Such changes affect the retention times of analytes eluted from the chromatographic column.
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公开(公告)号:WO2023003771A1
公开(公告)日:2023-01-26
申请号:PCT/US2022/037288
申请日:2022-07-15
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor: RAYMOND, Timothy M. , ANDERSON, Sean Eric
Abstract: A method for regulating a volume of liquid delivered by a peristaltic pump includes: sensing an ambient temperature of the peristaltic pump (220), determining at least one of a motor speed and a motor operation duration based on the sensed ambient temperature (230), and operating the pump motor at a determined motor speed or motor operation duration to deliver a selected volume of liquid from the peristaltic pump (240). A peristaltic pump system with the necessary structural features to perform this method is also disclosed.
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公开(公告)号:EP4374073A1
公开(公告)日:2024-05-29
申请号:EP22753852.7
申请日:2022-07-15
Applicant: Waters Technologies Corporation
Inventor: RAYMOND, Timothy M. , ANDERSON, Sean Eric
CPC classification number: F04B43/12 , F04B43/0081 , F04B49/065 , F04B13/00 , F04B2207/0320130101 , F04B2207/04320130101 , F04B2207/04420130101 , F04B43/09
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公开(公告)号:EP4517089A2
公开(公告)日:2025-03-05
申请号:EP24212225.7
申请日:2020-11-25
Applicant: Waters Technologies Corporation
Inventor: RAYMOND, Timothy M. , WALDEN, Christopher , ANDERSON, Sean
IPC: F04B49/06
Abstract: Disclosed is a gradient proportioning valve for liquid chromatography that includes a plurality of inlet ports configured to receive a plurality of fluids, a manifold connected to each of the plurality of inlet ports configured to mix the plurality of fluids in a controlled manner to provide a fluid composition, the manifold including a plurality of conduits internal to the manifold, each of the plurality of conduits receiving fluid through a respective one of the plurality of inlet ports, an actuation mechanism having a piston located within a bored structure surrounding the piston, the actuation mechanism configured to open and close at least one of the plurality of conduits in a controlled manner where the piston and the bored structure have a tight tolerance configured to create a fluid tight seal, and a common outlet port configured to receive the fluid composition.
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公开(公告)号:EP4244614A1
公开(公告)日:2023-09-20
申请号:EP22704707.3
申请日:2022-01-31
Applicant: Waters Technologies Corporation
Inventor: RAYMOND, Timothy M. , MACKINNON, Peter , JACKSON, Michael R.
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