公开(公告)号：WO2023026251A1

公开(公告)日：2023-03-02

申请号：PCT/IB2022/058018

申请日：2022-08-26

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： XU, MingCheng ,  BROUSMICHE, Darryl W. ,  WYNDHAM, Kevin ,  WALSH, Daniel P. ,  LAWRENCE, Nicole L.

IPC: B01J20/28

Abstract: In various embodiments, the present disclosure pertains to organic polymer core-shell particles that comprise a non-porous organic polymer core (i.e., having a pore volume of less than 0.1 cc/g) and a porous organic polymer shell (i.e., having a pore volume of greater than 0.1 cc/g), in which the porous organic polymer shell has a pore size ranging from 100 Å to 3000 Å. In some embodiments, the present disclosure pertains to chromatographic separation devices that comprise such organic polymer core-shell particles. In some embodiments, the present disclosure pertains to chromatographic methods that comprise: (a) loading a sample onto a chromatographic column comprising such organic polymer core-shell particles and (b) flowing a mobile phase through the column.

公开(公告)号：WO2023026258A1

公开(公告)日：2023-03-02

申请号：PCT/IB2022/058031

申请日：2022-08-26

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： XU, MingCheng ,  BROUSMICHE, Darryl W. ,  WALSH, Daniel P. ,  LAWRENCE, Nicole L. ,  WYNDHAM, Kevin

IPC: B01J20/28

Abstract: In various embodiments, the present disclosure pertains to core-shell particles that comprise a porous hybrid organic-inorganic shell disposed on a surface-modified non-porous polymer particle core. In some embodiments, the present disclosure pertains to chromatographic separation devices that comprise such core-shell particles. In some embodiments, the present disclosure pertains to chromatographic methods that comprise: (a) loading a sample onto a chromatographic column comprising such core-shell particles and (b) flowing a mobile phase through the column.

公开(公告)号：EP4392179A1

公开(公告)日：2024-07-03

申请号：EP22769786.9

申请日：2022-08-26

Applicant: Waters Technologies Corporation

Inventor： XU, MingCheng ,  BROUSMICHE, Darryl W. ,  WALSH, Daniel P. ,  LAWRENCE, Nicole L. ,  WYNDHAM, Kevin

IPC: B01J20/28

CPC classification number: B01J20/28004 ,  B01J20/28071 ,  B01J20/28076 ,  B01J20/3293 ,  B01J20/3219 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3276 ,  B01J20/286 ,  B01J20/289 ,  B01D15/08

公开(公告)号：EP4392178A1

公开(公告)日：2024-07-03

申请号：EP22769780.2

申请日：2022-08-26

Applicant: Waters Technologies Corporation

Inventor： XU, MingCheng ,  BROUSMICHE, Darryl W. ,  WYNDHAM, Kevin ,  WALSH, Daniel P. ,  LAWRENCE, Nicole L.

IPC: B01J20/28

CPC classification number: B01J20/3293 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3276 ,  B01J20/28004 ,  B01J20/28078 ,  B01J20/28071 ,  B01J20/28076