INFORMATION PROCESSING APPARATUS, MICROSCOPE SYSTEM, AND INFORMATION PROCESSING METHOD

    公开(公告)号:US20240361245A1

    公开(公告)日:2024-10-31

    申请号:US18571834

    申请日:2022-02-21

    CPC classification number: G01N21/6458 G01N2201/1217 G01N2201/1247

    Abstract: Provided is an advantageous technique for determining a positive threshold value for use in analyzing a stained specimen fluorescence spectrum.
    An information processing apparatus includes a threshold value determination unit configured to determine a positive threshold value that is to be compared with image data of a plurality of image sections included in a stained fluorescence component image, in which the positive threshold value is a criterion for determining whether or not each of the plurality of image sections corresponds to a positive cell image. The threshold value determination unit determines the positive threshold value on the basis of an unstained fluorescence component image.

    Particle measuring apparatus
    3.
    发明授权
    Particle measuring apparatus 失效
    粒子测量仪

    公开(公告)号:US5017008A

    公开(公告)日:1991-05-21

    申请号:US328030

    申请日:1989-03-23

    Applicant: Koichi Akiyama

    Inventor: Koichi Akiyama

    Abstract: Disclosed is an apparatus for measuring particles or particulates in a fluid in a measuring cell provided with a measuring window through which a laser beam is projected or through which light scattered from the particles passes. The surface of the measuring window is spherical with a radius of curvature whose center is at a point on which the laser beam converges for measurement. With this arrangement, light focused on the convergence point or light coming from the point always passes through the interface between the window and the fluid in the cell at an angle that is normal thereto. Thus no reflection of the light passing through the window occurs at the interface with the result that fluctuations of the refractive index of the fluid in the cell do not effect the focusing point of the light.

    Apparatus and method for measuring interaction between measurement-target sample substance and bioactive substance
    4.
    发明授权
    Apparatus and method for measuring interaction between measurement-target sample substance and bioactive substance 失效
    用于测量目标样本物质与生物活性物质之间相互作用的仪器和方法

    公开(公告)号:US07453573B2

    公开(公告)日:2008-11-18

    申请号:US11905029

    申请日:2007-09-27

    Applicant: Nobuhiko Ogura

    Inventor: Nobuhiko Ogura

    CPC classification number: G01N21/553 G01N2201/1217

    Abstract: A measuring apparatus and a measuring method are configured to measure a concentration of an organic solvent in a sample solution, measure a concentration of the organic solvent in a concentration control solution, calculate a mixture amount by which the concentration control solution is mixed into the sample solution of a preset amount so that the concentration of the organic solvent in the sample solution is equal to a preset concentration based on the two concentrations, mix the concentration control solution of the calculated mixture amount with the sample solution of the preset amount, supply a mixture solution obtained by the mixing unit to a measurement region in which a bioactive substance is immobilized in advance, and measure an interaction between the bioactive substance and the sample substance in the mixture solution based on a result of measuring a refraction index of a light incident on the measurement region.

    Abstract translation: 配置测定装置和测定方法,测定样品溶液中的有机溶剂的浓度,测定浓度对照溶液中的有机溶剂的浓度,算出将浓度对照溶液混合到样品中的混合量 溶液,使得样品溶液中的有机溶剂的浓度基于两种浓度等于预设浓度,将计算出的混合物量的浓度对照溶液与预先设定量的样品溶液混合,供给 通过混合单元获得的混合溶液预先固定有生物活性物质的测量区域,并且基于测量光入射的折射率的结果测量混合溶液中生物活性物质与样品物质之间的相互作用 在测量区域。

    METHOD AND APPARATUS FOR MONITORING SURFACE PHENOMENA
    6.
    发明申请
    METHOD AND APPARATUS FOR MONITORING SURFACE PHENOMENA 审中-公开
    用于监测表面活性剂的方法和装置

    公开(公告)号:US20170067826A1

    公开(公告)日:2017-03-09

    申请号:US15123258

    申请日:2015-02-18

    Applicant: BioNavis Oy

    Abstract: A method for monitoring surface phenomena includes measuring a first surface plasmon resonance angle value (φSPR,REF) of a sample region (REG1), measuring a first critical angle value (φTIR,REF) of the sample region (REG1), causing a change of surface concentration (cM1,SRF) of an analyte (M1) at the sample region (REG1), changing the bulk composition at the sample region (REG1), measuring a second surface plasmon resonance angle value (φSPR(t)) of the sample region (REG1), measuring a second critical angle value (φTIR(t)) of the sample region (REG1), and determining an indicator value (φAUX(t)) indicative of the change of the surface concentration (cM1,SRF), wherein the indicator value (φAUX(t)) is determined from the second surface plasmon resonance angle value (φSPR(t)) by compensating an effect of the bulk composition, and wherein the magnitude (φCOMP) of said effect is determined by using the second critical angle value (φTIR(t)).

    Abstract translation: 一种用于监测表面现象的方法包括: - 测量样品区域(REG1)的第一表面等离子体共振角值(φSPR,REF), - 测量样品区域(REG1)的第一临界角度值(φTIR,REF) - 引起样品区域(REG1)处的分析物(M1)的表面浓度(cM1,SRF)的变化, - 改变样品区域(REG1)处的体积组分, - 测量第二表面等离子体共振角值(φSPR (t)), - 测量样本区域(REG1)的第二临界角度值(φTIR(t)),以及 - 确定指示变化的指标值(φAUX(t)) 通过补偿本体组合物的影响,从第二表面等离子体共振角度值(φSPR(t))确定指标值(φAUX(t))的表面浓度(cM1,SRF),其中大小(φCOMP )通过使用第二临界角度值(φTIR(t))来确定。

    Apparatus and method for measuring interaction between measurement-target sample substance and bioactive substance

    公开(公告)号:US20080079944A1

    公开(公告)日:2008-04-03

    申请号:US11905029

    申请日:2007-09-27

    Applicant: Nobuhiko Ogura

    Inventor: Nobuhiko Ogura

    CPC classification number: G01N21/553 G01N2201/1217

    Abstract: A measuring apparatus and a measuring method are configured to measure a concentration of an organic solvent in a sample solution, measure a concentration of the organic solvent in a concentration control solution, calculate a mixture amount by which the concentration control solution is mixed into the sample solution of a preset amount so that the concentration of the organic solvent in the sample solution is equal to a preset concentration based on the two concentrations, mix the concentration control solution of the calculated mixture amount with the sample solution of the preset amount, supply a mixture solution obtained by the mixing unit to a measurement region in which a bioactive substance is immobilized in advance, and measure an interaction between the bioactive substance and the sample substance in the mixture solution based on a result of measuring a refraction index of a light incident on the measurement region.

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