公开(公告)号：US20250146045A1

公开(公告)日：2025-05-08

申请号：US18941160

申请日：2024-11-08

Applicant: IDEXX Laboratories, Inc.

Inventor： Jeremy Hammond ,  JuiMing Lin ,  Julia Chase ,  Seana Gray ,  Sarah Roger

IPC: C12Q1/06 ,  G01N21/64

Abstract: An apparatus and method for detecting the type, presence or amount of bacteria in a sample. The apparatus and method involve staining a liquid sample with a fluorescent stain corresponding to bacteria and imaging one or more portions of the sample at a selected set of sample Z-axis heights, X-Y coordinates, or both, within the sample after a predetermined time to allow for non-bacterial components in the sample to settle out of solution. A calibration method for correlating the concentration or amount of bacteria in biological samples by different analysis methods including glass slide methods, agar plate colony culture methods and high precision methods.

公开(公告)号：US20250104852A1

公开(公告)日：2025-03-27

申请号：US18970072

申请日：2024-12-05

Applicant: IDEXX Laboratories, Inc.

Inventor： Eric Christopher Basford ,  Jason Bowie ,  Craig Taylor Davis ,  Keith Douglass ,  Regina Hyson

IPC: G16H40/20 ,  A61D99/00 ,  G06F3/16 ,  G06Q30/04 ,  G16H10/40 ,  G16H10/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/20 ,  G16H50/70

Abstract: An example method includes receiving a first order to conduct a first diagnostic test of a sample from a patient, sending the first order to the first diagnostic testing instrument for input into a queue of the first diagnostic testing instrument, receiving alerts and status of the diagnostic test as testing is performed and for indication of completion of the first diagnostic test, sending the alerts and status of the diagnostic test to a second computing device for notice to a technician, receiving an output of the first diagnostic test, generating a recommendation of follow-on testing to perform based on the output of the first diagnostic test, receiving confirmation to perform the follow-on testing, generating a second order to conduct a second diagnostic test of another sample from the patient, and sending the second order to the second diagnostic testing instrument for input into a queue for the second diagnostic testing instrument.

公开(公告)号：US12228578B2

公开(公告)日：2025-02-18

申请号：US17554557

申请日：2021-12-17

Applicant: IDEXX LABORATORIES, INC.

Inventor： Joshua Michael Boucher ,  Anton Mestek, Jr. ,  Clever Madrid ,  Jesse Stephen Buch

IPC: G01N33/68 ,  C07K14/29 ,  G01N33/569

Abstract: Rocky Mountain Spotted Fever (RMSF) is a vector borne disease that is caused by Rickettsia rickettsii infection. It is challenging to identify the disease in dogs and other mammals due to the cross-reacting antibodies from non-pathogenic Rickettsia spp. Provided herein are compositions and methods for detection and treatment of Rocky Mountain spotted fever (“RMSF”). The compositions specifically detect Rickettsia rickettsii and do not cross-react with other Rickettsia species providing rapid and accurate detection and diagnosis of RMSF.

公开(公告)号：US12198800B2

公开(公告)日：2025-01-14

申请号：US17108400

申请日：2020-12-01

Applicant: IDEXX Laboratories, Inc.

Inventor： Eric Christopher Basford ,  Jason Bowie ,  Craig Taylor Davis ,  Keith Douglass ,  Regina Hyson

IPC: G16H40/20 ,  A61D99/00 ,  G06F3/16 ,  G06Q30/04 ,  G16H10/40 ,  G16H10/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/20 ,  G16H50/70

Abstract: An example method includes receiving a first order to conduct a first diagnostic test of a sample from a patient, sending the first order to the first diagnostic testing instrument for input into a queue of the first diagnostic testing instrument, receiving alerts and status of the diagnostic test as testing is performed and for indication of completion of the first diagnostic test, sending the alerts and status of the diagnostic test to a second computing device for notice to a technician, receiving an output of the first diagnostic test, generating a recommendation of follow-on testing to perform based on the output of the first diagnostic test, receiving confirmation to perform the follow-on testing, generating a second order to conduct a second diagnostic test of another sample from the patient, and sending the second order to the second diagnostic testing instrument for input into a queue for the second diagnostic testing instrument.

公开(公告)号：US20240385106A1

公开(公告)日：2024-11-21

申请号：US18786662

申请日：2024-07-29

Applicant: IDEXX Laboratories Inc.

Inventor： Garland Christian Misener ,  Bailey R. Auspland

IPC: G01N21/27 ,  G01J3/02 ,  G01J3/28 ,  G01J3/42 ,  G01J3/427 ,  G01N33/72

Abstract: A method for calibrating sensitivity of a photometer includes measuring, by a double-beam spectrophotometer, an absorbance spectrum of a control solution, which has been diluted and includes a control substance. The method further includes linearly regressing the absorbance spectrum of the control solution over a predetermined range of wavelengths and determining whether a first slope of the linearly regressed absorbance spectrum of the control solution falls within a range of slopes of lines obtained from linearly regressing absorbance spectra of a plurality of reference solutions over the predetermined range of wavelengths. A concentration of chromophore in each reference solution is known and the absorbance spectra of the plurality of reference solutions have been obtained by the double-beam spectrophotometer.

公开(公告)号：US20240288458A1

公开(公告)日：2024-08-29

申请号：US18656690

申请日：2024-05-07

Applicant: IDEXX Laboratories Inc.

Inventor： Jonathan W. Lawrence ,  Mark R. Dumont ,  Jason J. Aguiar ,  John H. McGibbon ,  Nicholas P. Prince

IPC: G01N35/00 ,  G01N15/1404

CPC classification number: G01N35/0099 ,  G01N15/1404

Abstract: An analyzer having an inner chassis surrounded by a housing includes sample and dilution probes, a mixing housing including first and second mixing chambers, a flow cytometer including a flow cell, and sample and sheath pumps configured to perform first and second pluralities of tasks, respectively. The first plurality of tasks includes: aspirating sample into the sample probe, dispensing sample from the sample probe into the first and second mixing chambers, delivering first sample-dilution fluid mixture to the flow cell, and delivering second sample-dilution fluid mixture to the flow cell. The second plurality of tasks includes: dispensing sheath to the flow cell in cooperation with the delivery of the first sample-dilution fluid mixture to the flow cell, and dispensing sheath to the flow cell in cooperation with the delivery of the second sample-dilution fluid mixture to the flow cell.

公开(公告)号：US20240269670A1

公开(公告)日：2024-08-15

申请号：US18434614

申请日：2024-02-06

Applicant: IDEXX LABORATORIES, INC.

Inventor： Murthy Yerramilli ,  Jennifer Gagner ,  William Foster ,  Eugene Chan ,  Wayne Bell ,  Asante Malima

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/50273 ,  B01L3/502746 ,  B01L3/502761 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/0689 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0864 ,  B01L2300/123 ,  B01L2300/18 ,  B01L2400/0409 ,  B01L2400/0442

Abstract: A method for preparing analyzing a droplet on a surface of a cartridge, wherein the droplet comprises a plurality of particles is disclosed. The method includes transporting, via a plurality of electrodes of the cartridge, the droplet along a single path on the surface of the cartridge, wherein the single path is substantially linear and the plurality of electrodes is configured to transport the droplet along the single path on the surface of the cartridge. The method also includes analyzing the droplet at one or more locations along the single path on the surface of the cartridge.

公开(公告)号：US12037164B2

公开(公告)日：2024-07-16

申请号：US16875008

申请日：2020-05-15

Applicant: IDEXX Laboratories Inc.

Inventor： Daniel Howard Broder ,  Scott W. Wagner

IPC: B65D43/02 ,  C12M1/00 ,  C12M1/22

CPC classification number: B65D43/0218 ,  C12M23/10 ,  C12M23/52 ,  B65D2543/00092 ,  B65D2543/00296

Abstract: A culture dish includes a base and a lid. The base includes a side wall and a concave floor that define a first interior volume open at a top end of the base. The base further includes an annular rim between the floor and a bottom end thereof. The lid includes a side wall and a ceiling that define a second interior volume open at a bottom end of the lid. The lid further includes an annular rim extending radially outwardly therefrom. An inner surface of the side wall of the lid is configured for slidable receipt about an outer surface of the side wall of the base to engage the lid about the base with the first and second interior volumes overlapping one another to define a sealed, combined internal volume bounded by the side walls of the base and the lid, the floor, and the ceiling.

公开(公告)号：US20240209459A1

公开(公告)日：2024-06-27

申请号：US18391216

申请日：2023-12-20

Applicant: IDEXX Laboratories, Inc.

Inventor： Melissa Jane Beall ,  Phyllis Ione Tyrrell

IPC: C12Q1/6893 ,  C12Q1/6844

CPC classification number: C12Q1/6893 ,  C12Q1/6844 ,  C12Q2600/16

Abstract: Methods, kit, and primer/probe sets are provided for the differential species-specific detection of one or more Dipylidium caninum, Toxocara canis, Ancylostoma canimum, Cystoisospora canis, Trichuris vulpis or Giardia duodenalis in an animal host based on amplification and detection of target parasite-specific repetitive DNA elements via polymerase chain reaction.

公开(公告)号：US20240180511A1

公开(公告)日：2024-06-06

申请号：US18438691

申请日：2024-02-12

Applicant: IDEXX Laboratories, Inc.

Inventor： Michael Q. Bailey, Sr. ,  Scott Bender ,  Patrick Raymond Doyle ,  Pavan Durgempudi ,  Benjamin Litchfield ,  David Steines

IPC: A61B6/50 ,  G06F18/243 ,  G06N20/00 ,  G06T7/00 ,  G16H15/00 ,  G16H30/20 ,  G16H30/40 ,  G16H50/20 ,  G16H70/20

CPC classification number: A61B6/508 ,  G06F18/243 ,  G06N20/00 ,  G06T7/0014 ,  G16H15/00 ,  G16H30/20 ,  G16H30/40 ,  G16H50/20 ,  G16H70/20 ,  G06T2207/10116 ,  G06T2207/20081 ,  G06T2207/30004 ,  G06T2207/30168 ,  G06V2201/03

Abstract: An example method includes capturing, via an x-ray machine, a plurality of x-ray images of a patient covering a number of different anatomy of the patient in any order, using a machine learning algorithm to process the plurality of x-ray images for identification of an anatomy in respective x-ray images of the plurality of x-ray images, associating a label with each of the plurality of x-ray images based on the identification of the anatomy, positioning each of the plurality of x-ray images upright based on a preset coordinate scheme for the anatomy, arranging the plurality of x-ray images into a predetermined order based on the species of the patient, and generating and outputting a data file including the plurality of x-ray images in the predetermined order, positioned upright, and labeled.