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公开(公告)号：US20220011328A1
公开(公告)日：2022-01-13
申请号：US17371852
申请日：2021-07-09
Applicant: IDEXX Laboratories Inc.
Inventor： Jonathan W. Lawrence , David L. Connolly , Mark R. Dumont , Dragan Vidacic , Jason J. Aguiar , Anne M. Leavitt , John H. McGibbon , Bailey R. Auspland , Nicholas P. Prince , David L. White , Brady D. Jacques , Samuel F. Clift , Jared O. Ruehr , Richard Andrews
Abstract: An analyzer having an inner chassis surrounded by a housing includes sample and dilution probes, a mixing housing including first and second mixing chambers, a flow cytometer including a flow cell, and sample and sheath pumps configured to perform first and second pluralities of tasks, respectively. The first plurality of tasks includes: aspirating sample into the sample probe, dispensing sample from the sample probe into the first and second mixing chambers, delivering first sample-dilution fluid mixture to the flow cell, and delivering second sample-dilution fluid mixture to the flow cell. The second plurality of tasks includes: dispensing sheath to the flow cell in cooperation with the delivery of the first sample-dilution fluid mixture to the flow cell, and dispensing sheath to the flow cell in cooperation with the delivery of the second sample-dilution fluid mixture to the flow cell.
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公开(公告)号：US12050171B2
公开(公告)日：2024-07-30
申请号：US17831458
申请日：2022-06-03
Applicant: IDEXX Laboratories Inc.
Inventor： Garland Christian Misener , Bailey R. Auspland
CPC classification number: G01N21/274 , G01J3/027 , G01J3/42 , G01J3/427 , G01N33/721 , G01J2003/2879
Abstract: A method for calibrating sensitivity of a photometer includes measuring, by a double-beam spectrophotometer, an absorbance spectrum of a control solution, which has been diluted and includes a control substance. The method further includes linearly regressing the absorbance spectrum of the control solution over a predetermined range of wavelengths and determining whether a first slope of the linearly regressed absorbance spectrum of the control solution falls within a range of slopes of lines obtained from linearly regressing absorbance spectra of a plurality of reference solutions over the predetermined range of wavelengths. A concentration of chromophore in each reference solution is known and the absorbance spectra of the plurality of reference solutions have been obtained by the double-beam spectrophotometer.
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公开(公告)号：US20240385106A1
公开(公告)日：2024-11-21
申请号：US18786662
申请日：2024-07-29
Applicant: IDEXX Laboratories Inc.
Inventor： Garland Christian Misener , Bailey R. Auspland
Abstract: A method for calibrating sensitivity of a photometer includes measuring, by a double-beam spectrophotometer, an absorbance spectrum of a control solution, which has been diluted and includes a control substance. The method further includes linearly regressing the absorbance spectrum of the control solution over a predetermined range of wavelengths and determining whether a first slope of the linearly regressed absorbance spectrum of the control solution falls within a range of slopes of lines obtained from linearly regressing absorbance spectra of a plurality of reference solutions over the predetermined range of wavelengths. A concentration of chromophore in each reference solution is known and the absorbance spectra of the plurality of reference solutions have been obtained by the double-beam spectrophotometer.
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公开(公告)号：US20220390358A1
公开(公告)日：2022-12-08
申请号：US17831458
申请日：2022-06-03
Applicant: IDEXX Laboratories Inc.
Inventor： Garland Christian Misener , Bailey R. Auspland
Abstract: A method for calibrating sensitivity of a photometer includes measuring, by a double-beam spectrophotometer, an absorbance spectrum of a control solution, which has been diluted and includes a control substance. The method further includes linearly regressing the absorbance spectrum of the control solution over a predetermined range of wavelengths and determining whether a first slope of the linearly regressed absorbance spectrum of the control solution falls within a range of slopes of lines obtained from linearly regressing absorbance spectra of a plurality of reference solutions over the predetermined range of wavelengths. A concentration of chromophore in each reference solution is known and the absorbance spectra of the plurality of reference solutions have been obtained by the double-beam spectrophotometer.
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