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公开(公告)号:US09796648B2
公开(公告)日:2017-10-24
申请号:US15308016
申请日:2015-05-04
Applicant: University of Tennessee Research Foundation
Inventor: Xiaofei Ye
IPC: C07C45/52 , C07C45/82 , C07C51/00 , C07C29/76 , C07C51/235 , B01J21/04 , B01J21/06 , B01J21/08 , B01J23/30 , B01J23/887 , B01J29/40 , B01J3/00 , B01J3/04 , C07C47/22
CPC classification number: C07C45/52 , B01J3/008 , B01J3/04 , B01J21/04 , B01J21/066 , B01J21/08 , B01J23/30 , B01J23/8877 , B01J29/40 , C07C29/76 , C07C45/82 , C07C47/22 , C07C51/235 , Y02P20/584 , Y02P20/588 , C07C31/225 , C07C57/04
Abstract: Methods and systems for suppressing coking in dehydration reactions catalyzed by solid acids. Dehydration reactions catalyzed by one or more solid acid catalysts can be performed in the presence of a super critical carbon dioxide medium which prevents or minimizes coking of the solid acid catalysts. Methods and systems are provided for producing glycerol products, such as acrolein, acrylic acid, acetol, by performing a dehydration reaction of glycerol using one or more solid acid catalysts in the presence of a super critical carbon dioxide reaction medium. Such methods and systems can be nm for extended periods of time, or continuously, due to catalyst regeneration and/or recycling. Such methods and systems are configured to produce glycerol products from crude glycerol feedstock with minimal pretreatment.
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公开(公告)号:US09774246B2
公开(公告)日:2017-09-26
申请号:US14511809
申请日:2014-10-10
Applicant: University of Tennessee Research Foundation
CPC classification number: H02M1/4216 , H02M7/217 , H02M7/219 , Y02B70/126
Abstract: A three-phase current source rectifier (CSR) with three AC inputs may include a controller, a free-wheeling diode with a cathode connected to a positive line and an anode connected to a negative line, three pairs of switches connected in parallel between the positive line and the negative line, and six pairs of diodes, each pair of the diodes connected in series. Each two pairs of the diodes may be connected in parallel with each other and in series with a respective pair of switches. Each AC input may be connected to between each of two pairs of the diodes.
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公开(公告)号:US20170267722A1
公开(公告)日:2017-09-21
申请号:US15605877
申请日:2017-05-25
Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
Inventor: Jonathan S. Wall , Timothy E. Sparer , Stephen J. Kennel
IPC: C07K7/08 , C07K14/00 , C07K14/035 , A61K38/16 , C07K14/045
CPC classification number: C07K7/08 , A61K38/16 , C07K14/001 , C07K14/035 , C07K14/045
Abstract: Disclosed are methods of treating and/or inhibiting a viral infection in a subject. The methods include administering a therapeutically effective amount of heparin-binding peptide. Also disclosed herein are methods for blocking viral binding to a cell. Further disclosed are anti-viral compositions for administration to a subject infected with a virus. Administration of the anti-viral composition inhibits viral infection of the subject.
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公开(公告)号:US09753959B2
公开(公告)日:2017-09-05
申请号:US14513497
申请日:2014-10-14
Applicant: University of Tennessee Research Foundation
Inventor: J. Douglas Birdwell , Mark E. Dean , Margaret Drouhard , Catherine Schuman
CPC classification number: G06F17/30312 , G06N3/02 , G06N3/049 , G06N3/063 , G06N3/0635 , G06N3/08 , G06N3/086 , G06N3/10
Abstract: A method and apparatus for constructing one of a neuroscience-inspired artificial neural network and a neural network array comprises one of a neuroscience-inspired dynamic architecture, a dynamic artificial neural network array and a neural network array of electrodes associated with neural tissue such as a brain, the method and apparatus having a special purpose display processor. The special purpose display processor outputs a display over a period of selected reference time units to demonstrate a neural pathway from, for example, one or a plurality of input neurons through intermediate destination neurons to an output neuron in three dimensional space. The displayed neural network may comprise neurons and synapses in different colors and may be utilized, for example, to show the behavior of a neural network for classifying hand-written digits between values of 0 and 9 or recognizing vertical/horizontal lines in a grid image of lines.
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公开(公告)号:US20170247834A1
公开(公告)日:2017-08-31
申请号:US15505465
申请日:2015-08-28
Applicant: University of Tennessee Research Foundation
Inventor: Joseph BOZELL , David Harper , Nicole Labbe , Omid Hosseinaei , Timothy Rials
CPC classification number: D21C11/0007 , C08B37/0057 , C08H8/00 , D01C1/02 , D01D5/0038 , D01F9/17 , D21C3/20
Abstract: A comprehensive process for treating lignocellulosic biomass in order to separate the biomass into its component parts, the process comprising: a) contacting the lignocellulosic biomass with a first solvent for a period of time and at a first temperature at a severity in the range of about 2 to about 4 to remove extractive components and a portion of ash from the biomass; b) contacting the biomass from step (a) with a second solvent, and optional catalyst, at a second temperature at a severity in the range of about 1 to 5 to remove hemicelluloses and additional ash from the biomass; and c) separating the biomass from step (b) into a lignin product and a cellulose product by contacting the biomass from step (b) with a third solvent at a severity in the range of about 1.5 to 5 to provide a spent liquor product and a solid fraction containing cellulose.
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公开(公告)号:US09744108B2
公开(公告)日:2017-08-29
申请号:US14771222
申请日:2014-02-28
Applicant: University of Tennessee Research Foundation
Inventor: Mojdeh Dehghan , Daranee Versluis-Tantbirojn
CPC classification number: A61K8/21 , A61K8/19 , A61K8/20 , A61K8/24 , A61K8/41 , A61K8/64 , A61K8/97 , A61K2800/20 , A61K2800/884 , A61Q11/00
Abstract: Methods and compositions are provided for reducing, treating or preventing dental erosion in a patient in need of such treatment, the methods and compositions comprising administering a therapeutically effective amount of an alkalinizing agent and a re-mineralizing agent to the teeth. Dental erosion is a significant oral health problem that affects millions of individuals around the world. Erosive tooth wear can cause significant tooth damage compromising the esthetics and function of teeth, requiring extensive dental treatment.
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公开(公告)号:US20170240506A1
公开(公告)日:2017-08-24
申请号:US15398672
申请日:2017-01-04
Applicant: University of Tennessee Research Foundation
Inventor: James T. Dalton , Duane D. Miller
IPC: C07C255/54
CPC classification number: C07C255/54 , A61K31/277
Abstract: This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.
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公开(公告)号:US20170219719A1
公开(公告)日:2017-08-03
申请号:US15493449
申请日:2017-04-21
Inventor: Charles L. Melcher , Mohit Tyagi , Merry Koschan , Peter Carl Cohen , Matthias Schmand , Mark S. Andreaco , Lars Aldon Eriksson
CPC classification number: G01T1/2002 , G01T1/2018 , G01T1/202 , G01T1/2023
Abstract: A radiation detection system may include a detector. The detector may include a scintillator to convert ionizing radiation, which originates externally to the detector, into visible light, a sensor configured to detect the visible light from the scintillator, and a light source. The radiation detection system may further include a controller programmed to control the light source to expose the scintillator to a light to saturate traps in the scintillator.
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公开(公告)号:US20170200457A1
公开(公告)日:2017-07-13
申请号:US14992974
申请日:2016-01-11
Inventor: Jidong Chai , Yilu Liu , Jiecheng Zhao , Wenxuan Yao , Thomas J. King
IPC: G10L25/51 , G10L25/30 , G10L21/038 , G10L21/0232
Abstract: Systems and methods for detecting a tampering and identifying a location of a digital recording are provided. A frequency sequence and a phase angle sequence may be extracted from the digital recording. A portion of the frequency sequence may be matched to one of a plurality of reference frequency sequences, and a portion of the phase angle sequence may be matched to one of a plurality of reference phase angle sequences. Tampering of the digital recording may be detected when the frequency and phase sequences differ from the matched reference sequences. Moreover, a noise sequence may be extracted from the extracted frequency sequence. A location of the digital recording may be identified by matching the noise sequence to one of a plurality of noise sequences of the plurality of reference frequency sequences.
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公开(公告)号:US09695356B1
公开(公告)日:2017-07-04
申请号:US15462391
申请日:2017-03-17
Applicant: University of Tennessee Research Foundation
Inventor: Luis Stand , Mariya Zhuravleva , Charles L. Melcher
CPC classification number: C09K11/7733 , G01T1/2006 , G01T1/2018 , G01T1/2023 , G21K4/00 , G21K2004/10
Abstract: Metal halide scintillators are described. More particularly, the scintillators include doped (e.g., europium-doped) ternary metal halides, such as those of the formulas A2BX4 and AB2X5, wherein A is an alkali metal, such as Li, Na, K, Rb, Cs or any combination thereof; B is an alkali earth metal, such as Be, Mg, Ca, Sr, Ba or any combination thereof; and X is a halide, such as Cl, Br, I, F or any combination thereof. Radiation detectors comprising the novel metal halide scintillators and other ternary metal halides, such as those of the formulas A2EuX4 and AEu2X5, wherein A is an alkali metal and X is a halide, are also described.
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