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公开(公告)号:US20220390358A1
公开(公告)日:2022-12-08
申请号:US17831458
申请日:2022-06-03
Applicant: IDEXX Laboratories Inc.
Inventor: Garland Christian Misener , Bailey R. Auspland
Abstract: A method for calibrating sensitivity of a photometer includes measuring, by a double-beam spectrophotometer, an absorbance spectrum of a control solution, which has been diluted and includes a control substance. The method further includes linearly regressing the absorbance spectrum of the control solution over a predetermined range of wavelengths and determining whether a first slope of the linearly regressed absorbance spectrum of the control solution falls within a range of slopes of lines obtained from linearly regressing absorbance spectra of a plurality of reference solutions over the predetermined range of wavelengths. A concentration of chromophore in each reference solution is known and the absorbance spectra of the plurality of reference solutions have been obtained by the double-beam spectrophotometer.
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公开(公告)号:US11460705B2
公开(公告)日:2022-10-04
申请号:US17391889
申请日:2021-08-02
Applicant: Magic Leap, Inc.
Inventor: Nicole Elizabeth Samec , Nastasja U. Robaina , Adrian Kaehler , Mark Baerenrodt , Eric Baerenrodt , Christopher M. Harrises , Tammy Sherri Powers
IPC: G02B27/01 , G01J3/02 , G01J3/42 , A61B5/1455 , A61B5/11 , A61B5/00 , G06F3/03 , G01J3/10 , G06F3/01 , G01J3/28 , G01J3/427 , G01N21/359 , G01N33/483 , F21V8/00 , G02B27/00
Abstract: In some embodiments, a system comprises a head-mounted frame removably coupleable to the user's head; one or more light sources coupled to the head-mounted frame and configured to emit light with at least two different wavelengths toward a target object in an irradiation field of view of the light sources; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering the target object; and a controller operatively coupled to the one or more light sources and detectors and configured to determine and display an output indicating the identity or property of the target object as determined by the light properties measured by the detectors in relation to the light properties emitted by the light sources.
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公开(公告)号:US20220026717A1
公开(公告)日:2022-01-27
申请号:US17391889
申请日:2021-08-02
Applicant: Magic Leap, Inc.
Inventor: Nicole Elizabeth Samec , Nastasja U. Robaina , Adrian Kaehler , Mark Baerenrodt , Eric Baerenrodt , Christopher M. Harrises , Tammy Sherri Powers
IPC: G02B27/01 , G01J3/02 , G01J3/42 , A61B5/1455 , A61B5/11 , A61B5/00 , G06F3/03 , G01J3/10 , G06F3/01 , G01J3/28 , G01J3/427 , G01N21/359 , G01N33/483 , F21V8/00
Abstract: In some embodiments, a system comprises a head-mounted frame removably coupleable to the user's head; one or more light sources coupled to the head-mounted frame and configured to emit light with at least two different wavelengths toward a target object in an irradiation field of view of the light sources; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering the target object; and a controller operatively coupled to the one or more light sources and detectors and configured to determine and display an output indicating the identity or property of the target object as determined by the light properties measured by the detectors in relation to the light properties emitted by the light sources.
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公开(公告)号:US11112310B2
公开(公告)日:2021-09-07
申请号:US16555130
申请日:2019-08-29
Applicant: Dublin City University
Inventor: Prince Anandarajah , Eamonn Patrick Martin
Abstract: A gain switched dual comb spectroscopy device for spectroscopically detecting a sample substance, comprising a first slave laser light source configured to generate a first frequency comb having a first comb free spectral range, and a second slave laser light source configured to generate a second frequency comb having a second comb free spectral range which is different from the first comb free spectral range. A master laser light source is configured to inject seed light in to both slave laser light sources therewith to injection lock the generation of both the first and the second frequency combs. A photodetector part is arranged to combine the first and the second frequency combs and to detect a beat signal the spectrum of which comprises a third frequency comb including beat tones produced by interference between the combined first and second frequency combs.
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公开(公告)号:US20210262857A1
公开(公告)日:2021-08-26
申请号:US17240172
申请日:2021-04-26
Applicant: The Trustees of Princeton University
Inventor: Lukasz STERCZEWSKI , Jonas WESTBERG , Gerard WYSOCKI
Abstract: Disclosed herein is an all-digital phase and timing correction procedure for coherent averaging in dual-comb and multiheterodyne spectroscopy—applicable to any dual-comb spectroscopy setup. It can account for large frequency/phase instabilities of the used sources, yielding a significant reduction of the noise pedestal and an increase in signal-to-noise ratio (SNR) of the radio frequency (RF) beat notes. This technique is computationally efficient and can be conveniently implemented either as a post-processing algorithm or in a real-time data acquisition and processing platform without the necessity of adding any additional optical elements to the dual-comb spectroscopy system. By implementing this technique, the performance of any comb- or comb-like-source-based DCS system with a sufficient degree of mutual coherence between the optical modes can be improved in terms of SNR and number of spectroscopically-usable RF beat notes. The described technique is compatible with a DC-centered RF spectrum, where the negative frequencies are folded to the positive domain to double the number of beat notes within the detector bandwidth. The technique enables coherent averaging over extended time-scales even for free-running combs, thus increasing the sensitivity of absorption and dispersion DCS measurements.
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公开(公告)号:US11041758B2
公开(公告)日:2021-06-22
申请号:US16095323
申请日:2017-04-13
Applicant: Apple Inc.
Inventor: Trent D. Ridder , Mark Alan Arbore , Gary Shambat , Robert Chen , David I. Simon , Miikka M. Kangas
Abstract: Methods and systems for measuring one or more properties of a sample are disclosed. The methods and systems can include multiplexing measurements of signals associated with a plurality of wavelengths without adding any signal independent noise and without increasing the total measurement time. One or more levels of encoding, where, in some examples, a level of encoding can be nested within one or more other levels of encoding. Multiplexing can include wavelength, position, and detector state multiplexing. In some examples, SNR can be enhanced by grouping together one or more signals based on one or more properties including, but not limited to, signal intensity, drift properties, optical power detected, wavelength, location within one or more components, material properties of the light sources, and electrical power. In some examples, the system can be configured for optimizing the conditions of each group individually based on the properties of a given group.
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公开(公告)号:US10976241B2
公开(公告)日:2021-04-13
申请号:US16121909
申请日:2018-09-05
Applicant: Regeneron Pharmaceuticals, Inc.
Inventor: Andria Skinner , Natallia Kulyba
IPC: G01N21/31 , G01N33/68 , G01N30/02 , A61K47/68 , G16B5/00 , G16C20/30 , G01J3/427 , G01N21/27 , G01N30/88 , G01N21/33 , B01D15/34
Abstract: The present disclosure provides methods of assessing DAR of ADC products that provide advantages over known methods. Specifically, methods of the disclosure can be used in high-throughput applications and/or without having to dilute ADC samples during the assessment.
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公开(公告)号:US20210055212A1
公开(公告)日:2021-02-25
申请号:US16492802
申请日:2018-03-07
Applicant: ELICHENS
Inventor: Hélène Duprez
IPC: G01N21/3504 , G01N21/31 , G01J3/427 , G01J3/02
Abstract: A gas sensor comprises a chamber configured to receive a gas; a light source configured to emit a light wave propagating through the chamber in an emission cone; a measurement photodetector and a reference photodetector, each configured to detect a light wave emitted by the light source and having passed through the chamber. The chamber extends between two transverse walls, arranged opposite one another and connected to one another by a peripheral wall extending therebetween, about a longitudinal axis (Z), and comprising a first reflective segment configured to receive a first portion of the emission cone to reflect it toward the measurement photodetector, thus forming a measurement cone converging toward the measurement photodetector. A second reflective segment of the peripheral wall is configured to receive a second portion of the emission cone to reflect it toward the reference photodetector, thus forming a reference cone converging toward the reference photodetector.
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公开(公告)号:US10558047B2
公开(公告)日:2020-02-11
申请号:US15713420
申请日:2017-09-22
Applicant: Magic Leap, Inc.
Inventor: Nicole Elizabeth Samec , Nastasja U. Robaina , Adrian Kaehler , Mark Baerenrodt , Eric Baerenrodt , Christopher M. Harrises , Tammy Sherri Powers
IPC: G02B27/01 , G01J3/10 , G01J3/28 , G01J3/427 , G01N21/359 , G01N33/483 , F21V8/00 , G06F3/01 , G01J3/42
Abstract: In some embodiments, a system comprises a head-mounted frame removably coupleable to the user's head; one or more light sources coupled to the head-mounted frame and configured to emit light with at least two different wavelengths toward a target object in an irradiation field of view of the light sources; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering the target object; and a controller operatively coupled to the one or more light sources and detectors and configured to determine and display an output indicating the identity or property of the target object as determined by the light properties measured by the detectors in relation to the light properties emitted by the light sources.
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公开(公告)号:US10241044B2
公开(公告)日:2019-03-26
申请号:US16056531
申请日:2018-08-07
Applicant: Airware, Inc.
Inventor: Jacob Y Wong , Thomas Campbell
IPC: G01N21/59 , G01N33/49 , G01N21/35 , G01N21/27 , G01J3/42 , G01N21/3577 , G01J3/427 , G01N21/47 , G01N21/31
Abstract: For determining concentration of targeted molecules MG in a liquid sample admixed with interfering molecules MJ which overlap their absorption band, a special NDIR sampling and calibration technique is employed. Besides the signal source, a reference and one or more interference sources are added. The selection of the wavelength for the interference sources enables its measured transmittance value to be used for deciding the validity of the calibration curve for molecules MG in the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.
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