Semi-automated non-contrast magnetic resonance angiography (MRA)
    101.
    发明授权
    Semi-automated non-contrast magnetic resonance angiography (MRA) 有权
    半自动非对比磁共振血管造影(MRA)

    公开(公告)号:US09579041B2

    公开(公告)日:2017-02-28

    申请号:US13479680

    申请日:2012-05-24

    Inventor: Mitsue Miyazaki

    CPC classification number: A61B5/055 A61B5/0037 A61B5/201

    Abstract: A magnetic resonance imaging (MRI) system semi-automatically performs non-contrast magnetic resonance angiography (MRA). An operator display and control input port configures the MRI system to effect semi-automated non-contrast MRA imaging with spatially selective tag and venous suppression RF pulses and/or black blood time interval (BBTI) parameters in a non-contrast MRA data acquisition sequence where such parameters are automatically determined within predetermined, respectively corresponding, spatial regions of patient anatomy. Such automatically determined non-contrast MRA imaging parameters may be entirely automatically set and used or, alternatively, may be displayed to an operator for acceptance and/or change before being used.

    Abstract translation: 磁共振成像(MRI)系统半自动执行非对比磁共振血管造影(MRA)。 操作者显示和控制输入端口配置MRI系统以在非对比MRA数据采集序列中进行空间选择性标签和静脉抑制RF脉冲和/或黑血时间间隔(BBTI)参数的半自动非对比MRA成像 其中这些参数在患者解剖结构的预定的相应的空间区域内自动确定。 这种自动确定的非造影MRA成像参数可以被完全自动设置和使用,或者替代地,可以在使用之前被显示给操作者以进行接受和/或改变。

    HEMODYNAMIC-SIGNAL-BASED ELECTRODE-TISSUE CONTACT DETECTION
    102.
    发明申请
    HEMODYNAMIC-SIGNAL-BASED ELECTRODE-TISSUE CONTACT DETECTION 审中-公开
    基于HEMODYNAMIC-SIGNAL的电极组织接触检测

    公开(公告)号:US20170007158A1

    公开(公告)日:2017-01-12

    申请号:US14795529

    申请日:2015-07-09

    Abstract: A method includes disposing at least one pair of electrodes in or on a body of a subject, including disposing at least one intrarenal electrode of the pair in a renal artery. Control circuitry is activate to (a) apply electrical pulses between the pair of electrodes, (b) calculate at least one time-varying component of electrode-tissue impedance based on applying the pulses, (c) sense a periodic hemodynamic signal of the subject, (d) calculate a level of correlation between the at least one time-varying component of the electrode-tissue impedance and the periodic hemodynamic signal, and (e) based on the level of correlation, ascertain a level of contact between the at least one intrarenal electrodes and a wall of the renal artery. In response to the level of contact being less than a threshold level of contact, a disposition of the at least one intrarenal electrodes in the renal artery is adjusted.

    Abstract translation: 一种方法包括将至少一对电极设置在受试者的身体内或身体上,包括在肾动脉中设置该对的至少一个肾内电极。 控制电路被激活以(a)在一对电极之间施加电脉冲,(b)基于施加脉冲计算电极组织阻抗的至少一个时变分量,(c)感测受试者的周期性血液动力学信号 ,(d)计算电极组织阻抗的至少一个时变分量与周期性血液动力学信号之间的相关程度,以及(e)基于相关度,确定至少 一个肾内电极和肾动脉壁。 响应于接触水平小于阈值接触水平,调整肾动脉中的至少一个肾内电极的布置。

    METHOD AND APPARATUS FOR RAPID QUANTIFICATION OF AN ANALYTE IN BREATH
    103.
    发明申请
    METHOD AND APPARATUS FOR RAPID QUANTIFICATION OF AN ANALYTE IN BREATH 有权
    用于快速分析呼吸道分析仪的方法和装置

    公开(公告)号:US20160245797A1

    公开(公告)日:2016-08-25

    申请号:US15040790

    申请日:2016-02-10

    Abstract: A method of determining the concentration of an analyte of interest in breath. The method includes obtaining a disposable cartridge comprising a reaction chamber, a liquid chamber, and a window to permit determination of a color intensity in the reaction chamber, directing a volume of breath into the cartridge, and initiating a sequence whereby liquid is released from the liquid container into the reaction chamber to cause a reaction which produces a change in the intensity of a color viewable through the window. The intensity of the color corresponds to the concentration of the analyte of interest. The reaction progresses through a kinetic phase and eventually reaches equilibrium. The sequence additionally includes measuring the intensity of the color at a point in the kinetic phase, to determine the concentration of the analyte of interest in breath.

    Abstract translation: 确定呼吸中感兴趣的分析物的浓度的方法。 该方法包括获得包括反应室,液体室和窗口的一次性盒,以允许确定反应室中的颜色强度,将一定体积的呼吸引导到盒中,并启动序列,从而使液体从 液体容器进入反应室以引起反应,其产生通过窗口可观察到的颜色强度的变化。 颜色的强度对应于感兴趣的分析物的浓度。 反应通过动力学阶段进行,最终达到平衡。 序列还包括在动力学相中的某一点测量颜色的强度,以确定感兴趣的分析物在呼吸中的浓度。

    KIDNEY GLOMERULI MEASUREMENT SYSTEMS AND METHODS
    104.
    发明申请
    KIDNEY GLOMERULI MEASUREMENT SYSTEMS AND METHODS 审中-公开
    KIDNEY GLOMERULI测量系统和方法

    公开(公告)号:US20160206235A1

    公开(公告)日:2016-07-21

    申请号:US15082095

    申请日:2016-03-28

    Inventor: Teresa Wu Min Zhang

    Abstract: Methods and systems for identifying blobs, for example kidney glomeruli, are disclosed. A raw image may be smoothed via a difference of Gaussians filter, and a Hessian analysis may be conducted on the smoothed image to mark glomeruli candidates. Exemplary candidate features are identified, such as average intensity AT, likelihood of blobness RT, and flatness ST. A clustering algorithm may be utilized to post prune the glomeruli candidates.

    Abstract translation: 公开了用于鉴定斑点的方法和系统,例如肾小球。 原始图像可以通过高斯滤波器的差异进行平滑,并且可以对平滑的图像进行Hessian分析以标记肾小球候选。 识别示例性候选特征,例如平均强度AT,斑点RT的可能性和平坦度ST。 可以使用聚类算法来修剪肾小球候选者。

    SYSTEM AND METHOD FOR MONITORING BLOOD FLOW CONDITION IN REGION OF INTEREST IN PATIENT'S BODY
    110.
    发明申请
    SYSTEM AND METHOD FOR MONITORING BLOOD FLOW CONDITION IN REGION OF INTEREST IN PATIENT'S BODY 审中-公开
    用于监测患者体内感兴趣区域血液流动条件的系统和方法

    公开(公告)号:US20150327779A1

    公开(公告)日:2015-11-19

    申请号:US14652965

    申请日:2013-12-18

    Abstract: A system and method are presented for use in monitoring blood flow conditions in a region of interest in a patient's body, such as a brain or kidney region. The monitoring system comprises a blood flow sensing system, and a control unit configured for communication with the sensing system to operate and to process and analyze output data of the sensing system. The blood flow sensing system is configured and operable for measuring a blood flow parameter from a first region being a region of interest in a patient's body and generating first measured data indicative thereof, and measuring a blood flow parameter in a second region being a tissue region outside the brain region and generating second measured data indicative thereof The control unit is configured for operating the sensing system for carrying out substantially simultaneous measurements on the region of interest and the tissue region outside the region of interest and recording the first and second measured data, and configured and operable for determining a predetermined function characterizing a relation between the first measured data and the second measured data, and generating output data indicative of said relation, being indicative of the blood flow condition in the region of interest.

    Abstract translation: 本发明提供一种系统和方法,用于监测患者身体(例如脑或肾脏区域)中感兴趣区域中的血流状况。 监测系统包括血液流量检测系统和被配置为与感测系统通信以操作和处理和分析感测系统的输出数据的控制单元。 血液流量感测系统被配置和操作用于测量来自患者身体中的感兴趣区域的第一区域的血流参数,并产生指示其的第一测量数据,以及测量作为组织区域的第二区域中的血流参数 在脑区域外部并产生指示其的第二测量数据。控制单元被配置用于操作感测系统,用于对感兴趣区域和感兴趣区域外的组织区域进行基本上同时的测量,并记录第一和第二测量数据, 并且被配置和可操作用于确定表征第一测量数据和第二测量数据之间的关系的预定函数,以及生成指示所述关系的输出数据,指示感兴趣区域中的血流状况。

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