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公开(公告)号：US20180221139A1
公开(公告)日：2018-08-09
申请号：US15896340
申请日：2018-02-14
Applicant: RAINBOW MEDICAL LTD.
Inventor： Zev SOHN , Yossi GROSS
IPC: A61F2/16
CPC classification number: A61F2/1648 , A61F2/1629 , A61F2/1651 , A61F2002/1681 , A61F2002/1682
Abstract: An accommodating intraocular lens implant is provided that includes (a) a bowl-shaped posterior component and (b) an anterior component, which includes an anterior floating lens unit, which includes an anterior lens; a circumferential rim; and levers, which connect the anterior floating lens unit to the circumferential rim, such that the anterior floating lens unit is movable toward and away from the circumferential ring in an anterior-posterior direction. The bowl-shaped posterior component and the anterior component are distinct from each other and not permanently fixed to each other, and are shaped so as to be assemblable together in situ in a human eye such that the circumferential rim contacts an interface region of an inner surface of the bowl-shaped posterior component, and the levers are pivotable about the interface region during motion of the anterior floating lens unit toward and away from the circumferential ring in the anterior-posterior direction.
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公开(公告)号：US20180193633A1
公开(公告)日：2018-07-12
申请号：US15742245
申请日：2016-07-07
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS
Abstract: A method for treating hydrocephalus is provided, including disposing midplane treatment electrodes over a superior sagittal sinus of a brain, outside and in electrical contact with a skull of a head of a subject identified as suffering from hydrocephalus, and disposing lateral treatment electrodes between 1 and 12 cm of a sagittal midplane of the skull. The subject is treated by electroosmotically driving cerebrospinal fluid (CSF) out of a ventricular system of the brain via a subarachnoid space of the brain to the superior sagittal sinus, by activating control circuitry to apply one or more treatment currents between (a) one or more of the midplane treatment electrodes and (b) one or more of the lateral treatment electrodes. Other embodiments are also described.
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公开(公告)号：US20170347952A1
公开(公告)日：2017-12-07
申请号：US15174144
申请日：2016-06-06
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS
CPC classification number: A61B5/4833 , A61B5/00 , A61B5/0002 , A61B5/0015 , A61B5/073 , A61J3/007 , A61J2200/30 , A61K9/4808 , A61K9/4825 , A61K9/4833 , A61M31/002
Abstract: Apparatus is provided that includes a drug capsule containing an oral drug, and a sensing apparatus that includes a housing and a sensor. The housing is shaped so as to define exactly one hemispherical portion and exactly one cylindrical portion, which together define an internal surface tightly fitted to at least a portion of an external surface of the drug capsule. The sensor includes first and second electrodes, which comprise first and second electrode surfaces, respectively; and circuitry, which (a) is attached to the housing, (b) is electrically coupled to the first and the second electrode surfaces, and (c) is configured to drive a current between the first and the second electrode surfaces. Other embodiments are also described.
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公开(公告)号：US20170120053A1
公开(公告)日：2017-05-04
申请号：US14926705
申请日：2015-10-29
Applicant: RAINBOW MEDICAL LTD.
Inventor： Gideon FOSTICK , Yossi GROSS
CPC classification number: A61N1/36082 , A61N1/0529 , A61N1/0534 , A61N1/306 , A61N1/327
Abstract: Apparatus is provided that includes a parenchymal electrode, configured to be implanted in brain parenchyma of a subject identified as at risk of or suffering from Alzheimer's disease; and a ventricular electrode, configured to be implanted in a ventricular system of a brain of the subject. Control circuitry is configured to drive the parenchymal and the ventricular electrodes to clear a substance from the brain parenchyma into the ventricular system. Other embodiments are also described.
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5.发明申请公开(公告)号：US20170007158A1
公开(公告)日：2017-01-12
申请号：US14795529
申请日：2015-07-09
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS , Yehuda ZADOK , Yoel ATLACEVITZ
IPC: A61B5/06 , A61B18/14 , A61B5/0215 , A61B5/00
CPC classification number: A61B5/063 , A61B5/0215 , A61B5/0245 , A61B5/0422 , A61B5/068 , A61B5/201 , A61B5/6858 , A61B5/6885 , A61B5/7221 , A61B5/7246 , A61B5/7475 , A61B18/1492 , A61B2017/00026 , A61B2018/0016 , A61B2018/00267 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00666 , A61B2018/00839 , A61B2018/00875 , A61B2090/065
Abstract: A method includes disposing at least one pair of electrodes in or on a body of a subject, including disposing at least one intrarenal electrode of the pair in a renal artery. Control circuitry is activate to (a) apply electrical pulses between the pair of electrodes, (b) calculate at least one time-varying component of electrode-tissue impedance based on applying the pulses, (c) sense a periodic hemodynamic signal of the subject, (d) calculate a level of correlation between the at least one time-varying component of the electrode-tissue impedance and the periodic hemodynamic signal, and (e) based on the level of correlation, ascertain a level of contact between the at least one intrarenal electrodes and a wall of the renal artery. In response to the level of contact being less than a threshold level of contact, a disposition of the at least one intrarenal electrodes in the renal artery is adjusted.
Abstract translation: 一种方法包括将至少一对电极设置在受试者的身体内或身体上，包括在肾动脉中设置该对的至少一个肾内电极。 控制电路被激活以（a）在一对电极之间施加电脉冲，（b）基于施加脉冲计算电极组织阻抗的至少一个时变分量，（c）感测受试者的周期性血液动力学信号 ，（d）计算电极组织阻抗的至少一个时变分量与周期性血液动力学信号之间的相关程度，以及（e）基于相关度，确定至少 一个肾内电极和肾动脉壁。 响应于接触水平小于阈值接触水平，调整肾动脉中的至少一个肾内电极的布置。
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Patent Agency Ranking
公开(公告)号：US20160331958A1
公开(公告)日：2016-11-17
申请号：US14709380
申请日：2015-05-11
Applicant: RAINBOW MEDICAL, LTD.
Inventor： Yossi GROSS , Zev SOHN , Roy Katz
IPC: A61N1/05
Abstract: Apparatus and methods are described, including apparatus for pacing a heart of a subject. The apparatus includes an implantable pulse generator (IPG) and a coiled lead connected to the IPG, The coiled lead includes a smaller-diameter coiled portion, a lumen of which having a first coil-lumen-diameter, and a larger-diameter coiled portion electrically in series with the smaller-diameter coiled portion, a lumen of the larger-diameter coiled portion having a second coil-lumen-diameter that is larger than the first coil-lumen-diameter. A perpendicular distance from a central longitudinal axis of the smaller-diameter coiled portion to the lumen of the larger-diameter coiled portion is greater than an outer radius of the smaller-diameter coiled portion, when the central longitudinal axis of the smaller-diameter coiled portion is parallel to a central longitudinal axis of the larger-diameter coiled portion, Other applications are also described.
Abstract translation: 描述了装置和方法，包括用于对对象心脏进行起搏的装置。 该装置包括可植入脉冲发生器（IPG）和连接到IPG的线圈引线。线圈引线包括较小直径的卷绕部分，其内腔具有第一线圈腔直径和较大直径的卷绕部分 与较小直径的卷绕部分电串联，较大直径的卷绕部分的内腔具有大于第一线圈管腔直径的第二线圈管腔直径。 当较小直径卷绕部分的中心纵向轴线较小直径卷绕部分的中心纵向轴线与较小直径螺旋部分的中心纵向轴线的距离大于较小直径卷绕部分的外半径时， 部分平行于较大直径卷绕部分的中心纵向轴线，还描述了其它应用。
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公开(公告)号：US20160324572A1
公开(公告)日：2016-11-10
申请号：US15147081
申请日：2016-05-05
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS , Yehuda ZADOK
CPC classification number: A61B18/1492 , A61B5/02007 , A61B5/0215 , A61B5/024 , A61B5/4848 , A61B5/6852 , A61B18/1206 , A61B2018/00214 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00773 , A61B2090/064 , A61B2505/05 , A61B2562/0247
Abstract: A method is provided, comprising: (1) applying an excitatory current to renal nerve fibers of a subject; (2) determining a change in a parameter of the subject in response to the excitatory current, the parameter being a fastest rate of increase in arterial pressure during a systolic upstroke of an arterial pressure wave of the subject; (3) in response to the change, deciding whether to ablate the renal nerve fibers; and (4) in response to the deciding, applying ablation energy to the renal nerve fibers. Other embodiments are also described.
Abstract translation: 提供了一种方法，包括：（1）向受试者的肾神经纤维施加兴奋性电流; （2）响应于兴奋性电流确定受试者的参数的变化，该参数是受试者的动脉压波的收缩期上升中行动压力的最快增加速率; （3）响应变化，决定是否消融肾神经纤维; （4）响应决定，向肾神经纤维施加消融能量。 还描述了其它实施例。
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公开(公告)号：US20150148861A1
公开(公告)日：2015-05-28
申请号：US14559907
申请日：2014-12-03
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS
CPC classification number: A61N1/3601 , A61N1/37223 , A61N1/3787
Abstract: Apparatus and methods are described, including apparatus for treating a subject for obstructive sleep apnea (OSA). The apparatus includes an implant, an imaging device, and a control unit. In response to a set of training images received from the imaging device, the control unit learns an association between a position of a head of the subject and OSA of the subject. In response to the association, the control unit establishes, for an OSA-related parameter, at least two distinct thresholds corresponding to respective different head positions. Subsequently, at a second time, the control unit selects a threshold that corresponds to the position of the subject's head, and if the value of the OSA-related parameter passes the selected threshold, treats the subject for OSA by driving the implant to apply current to an anatomical site of the subject. Other applications are also described.
Abstract translation: 描述了装置和方法，包括用于治疗受试者阻塞性睡眠呼吸暂停（OSA）的装置。 该装置包括植入物，成像装置和控制单元。 响应于从成像装置接收的一组训练图像，控制单元学习被摄体的头部的位置与被摄体的OSA之间的关联。 响应于关联，控制单元针对OSA相关参数建立与各个不同头部位置对应的至少两个不同阈值。 随后，第二时间，控制单元选择对应于被检者头部的位置的阈值，并且如果OSA相关参数的值通过所选择的阈值，则通过驱动植入物来施加电流来对待OSA的对象 到主题的解剖部位。 还描述了其它应用。
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公开(公告)号：US20150039046A1
公开(公告)日：2015-02-05
申请号：US14445443
申请日：2014-07-29
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS
CPC classification number: A61N1/3611 , A61B5/0031 , A61B5/0488 , A61B5/076 , A61B5/08 , A61B5/113 , A61B5/4818 , A61B5/4836 , A61N1/0548 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/37205 , A61N1/3756 , A61N1/3787
Abstract: Apparatus comprising (1) a breathing sensor, configured to detect a breathing-related factor of a subject; (2) at least a first electrode configured to be placed in a vicinity of a respective first hypoglossal nerve, and to be driven, in response to the detected breathing-related factor, to apply a first electrical current to the first hypoglossal nerve; (3) at least a second electrode configured to be placed in a vicinity of a respective second hypoglossal nerve, and to be driven, in response to the detected breathing-related factor, to apply a second electrical current to the second hypoglossal nerve; and (4) circuitry configured to, in response to a detected symmetry-related factor indicative of a degree of symmetry of the subject, configure at least one current selected from the group consisting of: the first current and the second current. Other embodiments are also described.
Abstract translation: 一种装置，包括：（1）呼吸传感器，被配置为检测受试者的与呼吸有关的因素; （2）至少第一电极，其被配置为放置在相应的第一舌下神经附近，并且响应于检测到的呼吸相关因素被驱动以向第一舌下神经施加第一电流; （3）至少第二电极，其被配置为放置在相应的第二舌下神经附近，并且响应于检测到的呼吸相关因素被驱动以向第二舌下神经施加第二电流; 以及（4）电路，被配置为响应于检测到的对象相关因素，指示对象的对称程度，配置从由以下组成的组中选择的至少一个电流：第一电流和第二电流。 还描述了其它实施例。
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公开(公告)号：US20140324128A1
公开(公告)日：2014-10-30
申请号：US13872794
申请日：2013-04-29
Applicant: RAINBOW MEDICAL LTD.
Inventor： Yossi GROSS
IPC: A61N1/32
CPC classification number: A61N1/327 , A61N1/0536 , A61N1/306 , A61N1/36082 , A61N1/36139
Abstract: Apparatus for driving fluid between first and second anatomical sites of a subject is provided, comprising (1) a first electrode, configured to be coupled to the first anatomical site of the subject; (2) a second electrode, configured to be coupled to the second anatomical site of the subject; and (3) a control unit, configured to (i) detect a pressure difference between the first and second anatomical sites, and (ii) in response to the detected pressure difference, drive fluid between the first and second anatomical sites by applying a treatment voltage between the first and second electrodes. Other embodiments are also described.
Abstract translation: 提供了用于在对象的第一和第二解剖部位之间驱动流体的装置，包括：（1）第一电极，被配置为联接到所述对象的第一解剖部位; （2）第二电极，被配置为联接到所述对象的第二解剖部位; （3）控制单元，其被配置为（i）检测第一和第二解剖部位之间的压力差，以及（ii）响应于检测到的压力差，通过施加治疗来驱动第一和第二解剖部位之间的流体 第一和第二电极之间的电压。 还描述了其它实施例。
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