公开(公告)号：US11187692B2

公开(公告)日：2021-11-30

申请号：US17038058

申请日：2020-09-30

Applicant: Texas Tech University System

Inventor： David Weindorf ,  Delaina Pearson ,  Somsubhra Chakraborty

IPC: G01J3/00 ,  G01N33/24 ,  G01N23/223 ,  G01N21/359 ,  G01N21/27 ,  G01J3/44

Abstract: An apparatus or method determines a content of the one or more elements of a solid matrix by scanning the solid matrix using a PXRF spectrometer and a color sensor, receiving a PXRF spectra from the PXRF spectrometer and a numerical color data from the color sensor, extracting a value for each of the one or more elements the PXRF spectra, determining the content of the one or more elements of the solid matrix using one or more processors and a predictive model that relates the value of each of the one or more elements and the numerical color data to the content of the one or more elements of the solid matrix, and providing the content of the one or more elements of the solid matrix to one or more input/output interfaces.

公开(公告)号：US11187583B2

公开(公告)日：2021-11-30

申请号：US16603589

申请日：2018-04-02

Applicant: Ariel Scientific Innovations Ltd.

Inventor： Shmuel Sternklar ,  Ziv Glasser

IPC: G01J3/44

Abstract: A method of spectroscopy, comprises: transmitting output radiation to a sample; collecting from the sample input radiation being indicative of interaction between the output radiation and the sample; modulating at least one of the output radiation and the input radiation, wherein at least one of the output radiation and the modulation is characterized by a scanned parameter; combining the input radiation, following the modulation, with a reference signal to provide a combined signal; processing the combined signal to construct a vector describing a dependence of a radiation property of the input radiation on the parameter; and at least partially identifying the sample or a change in comprises sample based on at least the vector.

公开(公告)号：US20210364440A1

公开(公告)日：2021-11-25

申请号：US16769699

申请日：2018-12-05

Applicant: Mitsubishi Hitachi Power Systems, Ltd.

Inventor： Jun SASAHARA ,  Yosuke ETO ,  Yosuke KITAUCHI ,  Tsutomu TOMIYAMA ,  Yoshihiro DEGUCHI

IPC: G01N21/65 ,  G01J3/44 ,  G01N33/22 ,  F02C9/22

Abstract: A Raman scattered light acquisition device includes an emitting optical system configured to guide excitation light into a fluid, a scattered light window configured to define a part of a flow path of the fluid and through which Raman scattered light from the fluid irradiated with the excitation light passes, and a scattered light receiving device having a light receiving surface receiving Raman scattered light passed through the scattered light window. The scattered light window and the light receiving surface of the scattered light receiving device are disposed at a position in which they are separated from an optical axis in the fluid in a radial direction within a range in which an optical path of the excitation light in the fluid is present in an optical axis direction in which the optical axis in the fluid which is an optical axis of the excitation light in the fluid extends.

公开(公告)号：US20210364385A1

公开(公告)日：2021-11-25

申请号：US17325529

申请日：2021-05-20

Applicant: ARAGON PHOTONICS LABS S.L.U.

Inventor： Hugo FIDALGO MARTINS ,  Miguel SORIANO AMAT ,  María del Rosario FERNÁNDEZ RUIZ ,  Sonia MARTÍN LÓPEZ ,  Miguel GONZÁLEZ HERRÁEZ ,  Javier PRECIADO GARBAYO ,  Asier VILLAFRANCA VELASCO

IPC: G01M11/00 ,  G01J3/26 ,  G01J3/44

Abstract: A method and a system for interrogating an optical fiber includes a probe signal that has a first frequency comb at a first repetition rate (Δf) injected into the optical fiber. A backscattering signal that includes the probe signal convolved with an impulse response of the optical fiber in reflection which is sensitive to at least one parameter being measured from the optical fiber is gathered. The backscattering signal is beaten with a local oscillator signal to generate a beating signal, the local oscillator signal including a second frequency comb at a second repetition rate that is offset from the first repetition rate (Δf+δf) and being mutually coherent with the first frequency comb. The resulting beating signal is analysed to thereby determine the at least one parameter being measured from the optical fiber.

公开(公告)号：US11181480B2

公开(公告)日：2021-11-23

申请号：US17068434

申请日：2020-10-12

Applicant: Paul Bartholomew

Inventor： Paul Bartholomew

IPC: G01J3/44 ,  G01N21/65 ,  G01N21/01

Abstract: A method for identifying minerals and other materials illuminates a mineral with monochromatic light for an illumination duration and a true Raman spectrum is determined. The true Raman spectrum data is compared to reference spectrums to identify the mineral or material by calculating an identification score for each reference Raman spectrum relative to the Raman spectrum data of the unknown material using a formula that includes both a coincident-peak term and a missing-peak-penalty term.

公开(公告)号：US20210349299A1

公开(公告)日：2021-11-11

申请号：US17235302

申请日：2021-04-20

Applicant: NATIONAL CHUNG CHENG UNIVERSITY

Inventor： HSIANG-CHEN WANG ,  KAI-CHUN LI ,  KAI-HSIANG KE ,  CHUN-WEN LIANG

IPC: G02B21/36 ,  G01J3/44 ,  G01N21/65 ,  G01J3/28

Abstract: A method for analyzing 2D material thin film and a system for analyzing 2D material thin film are disclosed. The detection method includes the following steps: capturing sample images of 2D material thin films; measuring the 2D material thin films by a Raman spectrometer; performing a visible light hyperspectral algorithm on the sample images by a processor to generate a plurality of visible light hyperspectral images; performing a training and validation procedure, performing an image feature algorithm on the visible light hyperspectral images, and establishing a thin film prediction model based on a validation; and capturing a thin-film image to be measured by the optical microscope, performing the visible light hyperspectral algorithm, and then generating a distribution result of the thin-film image to be measured according to an analysis of the thin film prediction model.

公开(公告)号：US20210316306A1

公开(公告)日：2021-10-14

申请号：US17357372

申请日：2021-06-24

Applicant: BERKELEY LIGHTS, INC.

Inventor： Paul M. LUNDQUIST ,  Paul M. LEBEL ,  Phillip Ronald Thomas JESS

IPC: B01L3/00 ,  B01L7/00 ,  G01J3/02 ,  G01J3/10 ,  G01J3/44 ,  G01N1/40 ,  G01N21/31 ,  G01N21/64 ,  G02B21/06 ,  G02B21/16 ,  G02B21/36

Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.

公开(公告)号：US11145411B2

公开(公告)日：2021-10-12

申请号：US14440987

申请日：2013-11-06

Applicant: CHEMIMAGE CORPORATION ,  Patrick Treado ,  Shona Stewart ,  Heather Kirschner ,  Ryan Priore ,  Alan Wilson

Inventor： Patrick Treado ,  Shona Stewart ,  Heather Kirschner ,  Ryan Priore ,  Alan Wilson

IPC: G01N21/65 ,  G01N33/49 ,  G16H50/20 ,  G16B40/00 ,  G01N33/574 ,  G01J3/44 ,  G01J3/18

Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.

公开(公告)号：US11143555B2

公开(公告)日：2021-10-12

申请号：US16480786

申请日：2018-01-25

Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK

Inventor： Giuliano Scarcelli ,  Eitan Edrei

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/10 ,  G01J3/18 ,  G01J3/44

Abstract: In a spectrometry setup where a first spectral component dominates a second spectral component having a different wavelength, diffraction of the first spectral component as it passes through the optical train of the spectrometer can produce spectral noise that obscures detection of the second spectral component. To reduce the spectral noise, the light from the spectrometer is subject to spatial filtering or interference such that effects of the first spectral component are removed, or at least reduced. The second spectral component can then be more readily detected by a detector after the spatial filtering or interference. In embodiments, the spatial filtering or interference may be provided by a filtering module, which may be installed in existing spectrometry setups or form part of a unitary spectrometry system.

公开(公告)号：US20210307613A1

公开(公告)日：2021-10-07

申请号：US17234461

申请日：2021-04-19

Applicant: Stryker European Operations Limited

Inventor： John Josef Paul FENGLER ,  Robert Anthony STEAD

IPC: A61B5/00 ,  H04N9/097 ,  H04N5/238 ,  G02B27/10 ,  H04N5/232 ,  A61B1/04 ,  A61B1/06 ,  G01J3/02 ,  A61B1/00 ,  A61B1/05 ,  G01J1/00 ,  G01J3/36 ,  G01J1/58 ,  H04N5/33 ,  H04N5/225 ,  G01J3/44 ,  G02B21/16 ,  G01J3/10 ,  H04N5/235 ,  H04N9/04

Abstract: A fluorescence imaging system for imaging an object, the system includes a white light provider that emits white light, an excitation light provider that emits excitation light in a plurality of excitation wavebands for causing the object to emit fluorescent light, a component that directs the white light and excitation light to the object and collects reflected white light and emitted fluorescent light from the object, a filter that blocks light in the excitation wavebands and transmits at least a portion of the reflected white light and fluorescent light, and an image sensor assembly that receives the transmitted reflected white light and the fluorescent light.