Abstract:
The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
Abstract:
A self-diagnosis method and apparatus for measuring results from blood analyzers, the method comprising: generating an acquisition transmittance curve according to the changes in transmittance rate of sample during a sample acquisition process; determining whether there is an anomaly in the acquisition process according to the acquisition transmittance rate curve; if there is no anomaly in the acquisition process, determining that the measurement results of the blood sample are credible; and if there is an anomaly in the acquisition process, determining that there is a doubt about the measured results of the blood samples, the self-diagnosis method and apparatus for measuring results from blood analyzer can improve the accuracy of self-diagnosis of measured results from blood analyzers, and reducing the false positive rate, at the same time, the workload of users in examining and verifying the measured results is reduced, thereby saving on measuring costs.
Abstract:
An analytical system is disclosed. The analytical system includes a storage container configured to store a plurality of capillaries. It also includes a gripper configured to receive at least one of the plurality of capillaries, and move the at least one capillary so that an end of the capillary contacts a sample in a sample container and draws the sample in the capillary. The system also includes a reader configured to detect a signal from the sample in the capillary.
Abstract:
A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.
Abstract:
A laser light source for emitting excitation light, a sample case, a photomultiplier tube, a fluorescence collecting optical system and so forth are embedded in a resin material that is transparent to the excitation light and the light including fluorescence emitted from a sample. The resin material is provided in at least part of a light path that guides the fluorescence in the fluorescence collecting optical system, and this resin forms a housing that holds the laser light source, the fluorescence collecting optical system, the photomultiplier and so forth. A pigment having wavelength characteristics for absorbing the excitation light, Raman light generated from the resin, and so forth is contained substantially in a uniform manner in a resin region that surrounds the light path through which the excitation light and the light including the fluorescence pass.
Abstract:
A method for achieving measurable sample heating in the vicinity of a probe microscope tip using Stimulated Raman Spectroscopy. Two laser sources, preferably in the UV visible or near IR illuminate the sample, preferably in overlapping diffraction limited spots. At least one of the sources is swept through a frequency range such that the difference frequency corresponds to IR spectral regions of interest. Selective Absorption by differing sample materials at the difference frequency causes measurable sample heating detectable by the probe tip related to IR spectral absorption bands. Thus very high spatial resolution IR spectroscopy may be achieved.
Abstract:
The invention relates to arrays with a plurality of capillaries being arranged in a plane and mechanically attached to the array, wherein the distance of adjacent capillaries is approximately 2.25 mm or an integer multiple thereof. At least one free end of each capillary projects from the array in such a way that the free ends of the capillaries may be simultaneously inserted into wells of a microwell plate.
Abstract:
The present invention relates to a method and an apparatus for a fast thermo-optical characterisation of particles. In particular, the present invention relates to a method and a device to measure the stability of (bio)molecules, the interaction of molecules, in particular biomolecules, with, e.g. further (bio)molecules, particularly modified (bio)molecules, particles, beads, and/or the determination of the length/size (e.g. hydrodynamic radius) ofindividual (bio)molecules, particles, beads and/or the determination of length/size (e.g. hydrodynamic radius).
Abstract:
An apparatus for taking an accurate photometric measurement of a liquid by way of forming a specimen volume of a controlled optical path length for use with photometric measurement equipment is disclosed herein. In some embodiments, the apparatus comprises a transparent body configured for displacing a volume of a fluid and at least one support element wherein the support element is configured to maintain the transparent body at a location such that specimen fluid may enter a void volume to form a specimen volume of a controlled optical path length. In some embodiments, the apparatus comprises a plurality of transparent bodies interconnected by a web such that the transparent bodies are maintained at a spacing arrangement which allows for them to be inserted into the wells of a microplate in order to create a plurality of specimen volumes of a controlled optical path length.
Abstract:
The present disclosure pertains to metal or dielectric nanostructures of the subwavelength scale within the grating lines of optical diffraction gratings. The nanostructures have surface plasmon resonances or non-plasmon optical resonances. A linear photodetector array is used to capture the resonance spectra from one of the diffraction orders. The combined nanostructure super-grating and photodetector array eliminates the use of external optical spectrometers for measuring surface plasmon or optical resonance frequency shift caused by the presence of chemical and biological agents. The nanostructure super-gratings can be used for building integrated surface enhanced Raman scattering (SERS) spectrometers. The nanostructures within the diffraction grating lines enhance Raman scattering signal light while the diffraction grating pattern of the nanostructures diffracts Raman scattering light to different directions of propagation according to their wavelengths. Therefore, the nanostructure super-gratings allows for the use of a photodetector array to capture the surface enhanced Raman scattering spectra.