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公开(公告)号：US20080018901A1
公开(公告)日：2008-01-24
申请号：US11780177
申请日：2007-07-19
Applicant: Peter Groot
Inventor： Peter Groot
CPC classification number: G01B9/0201 , G01B9/02057 , G01B9/02072 , G01B9/02084 , G01B9/0209 , G01B11/2441 , G01B2290/70
Abstract: In general, in one aspect, the invention features a method that includes transforming interferometry data acquired for a test sample using a low coherence imaging interferometry system to a frequency domain and, at a plurality of frequencies in the frequency domain, reducing contributions to the transformed interferometry data due to imperfections in the imaging interferometry system thereby producing compensated interferometry data. The errors are reduced based on variations between interferometry data acquired using the low coherence imaging interferometry system for a calibration sample and model interferometry data corresponding to data acquired for the calibration sample using a model interferometry system.
Abstract translation: 通常，在一个方面，本发明的特征在于一种方法，其包括将使用低相干成像干涉测量系统获得的测试样本的干涉测量数据变换到频域，并且在频域中的多个频率上减少对经变换的 由于成像干涉测量系统中的缺陷导致的干涉测量数据，从而产生补偿干涉测量数据。 基于使用用于校准样本的低相干成像干涉测量系统获取的干涉测量数据与对应于使用模型干涉测量系统为校准样品获得的数据的模型干涉测量数据之间的变化而减小误差。
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公开(公告)号：US20080013078A1
公开(公告)日：2008-01-17
申请号：US11828764
申请日：2007-07-26
Applicant: Adrian Podoleanu , David Jackson , John Rogers , George Dobre , Radu Cucu
Inventor： Adrian Podoleanu , David Jackson , John Rogers , George Dobre , Radu Cucu
CPC classification number: A61B3/102 , A61B5/0066 , G01B9/0201 , G01B9/02027 , G01B9/0203 , G01B9/02058 , G01B9/02063 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01N21/23 , G01N21/4795
Abstract: OCT apparatus includes an interferometer, having an input beam splitter and a 50/50 output splitter. The splitting ratio of the input splitter may be optimized depending on the source power of light source and on the mismatch of the balanced receiver. The input splitter is a plate beam-splitter to minimize the stray reflected light in the interferometer and allow sequential operation of the apparatus in the OCT or in the confocal regime. The switching between the two regimes may be at will, or synchronous with the en-face scanning which results in quasi-simultaneous OCT/confocal imaging or in alternatives frames, confocal and OCT. By using polarization sensitive elements, two channels are provided in each regime, OCT and confocal. The two confocal polarization sensitive channels may allow adjustments of compensators prior to OCT measurements or OCT imaging.
Abstract translation: OCT设备包括具有输入分束器和50/50输出分离器的干涉仪。 输入分路器的分频比可以根据光源的功率和平衡接收机的不匹配进行优化。 输入分路器是平板分光器，以最小化干涉仪中的杂散反射光，并允许在OCT或共聚焦状态下对装置的顺序操作。 两种方案之间的切换可以是随意的，或者与进行准同时OCT /共聚焦成像或替代帧，共聚焦和OCT的en-face扫描同步。 通过使用极化敏感元件，在每个方案中提供了两个通道，OCT和共聚焦。 两个共焦极化敏感通道可以允许在OCT测量或OCT成像之前调整补偿器。
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公开(公告)号：US07280222B2
公开(公告)日：2007-10-09
申请号：US11160948
申请日：2005-07-16
Applicant: Chian Chiu Li
Inventor： Chian Chiu Li
IPC: G01B11/02
CPC classification number: A61B5/0066 , A61B5/0059 , G01B9/0201 , G01B9/02019 , G01B9/02057 , G01B9/0209 , G01B9/02091 , G01B11/2441 , G01N21/49
Abstract: In a compact optical device, a light emitting area of a light source and a light sensing area of a detector are placed in proximity. The detector receives part of a beam which is reflected back to the source from a sample. As a result, a beam splitter is no longer needed. By eliminating the beam splitter and packing the light source and detector in closeness, dimensions of the optical device are reduced.
Abstract translation: 在紧凑的光学装置中，将光源的发光区域和检测器的感光区域放置在邻近处。 检测器接收从样品反射回源的一部分光束。 结果，不再需要分束器。 通过消除光束分离器并将光源和检测器封闭，光学装置的尺寸减小。
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公开(公告)号：US07126693B2
公开(公告)日：2006-10-24
申请号：US10811748
申请日：2004-03-29
Applicant: Matthew J. Everett , Yan Zhou
Inventor： Matthew J. Everett , Yan Zhou
IPC: G01B9/00
CPC classification number: G01M11/3181 , A61B5/0066 , A61B5/0084 , G01B9/0201 , G01B9/02044 , G01B9/02091 , G01B2290/40 , G01B2290/70 , G01N21/4795
Abstract: The present invention discloses simple and yet highly efficient configurations of optical coherence domain reflectometry systems. The combined use of a polarizing beam splitter with one or two polarization manipulator(s) that rotate the returned light wave polarization to an orthogonal direction, enables one to achieve high optical power delivery efficiency as well as fixed or predetermined output polarization state of the interfering light waves reaching a detector or detector array, which is especially beneficial for spectral domain optical coherence tomography. In addition, the system can be made insensitive to polarization fading resulting from the birefringence change in the sample and reference arms. Dispersion matching can also be easily achieved between the sample and the reference arm for high resolution longitudinal scanning.
Abstract translation: 本发明公开了光学相干畴反射系统的简单且高效的配置。 将偏振分束器与一个或两个偏振操纵器组合使用，其将返回的光波偏振旋转到正交方向，使得能够实现高的光功率传递效率以及干涉的固定或预定的输出偏振状态 光波到达检测器或检测器阵列，这对于光谱域光学相干断层扫描是特别有益的。 此外，该系统可以对由样品和参考臂中的双折射变化导致的偏振衰落不敏感。 也可以在样品和参考臂之间轻松实现色散匹配，实现高分辨率纵向扫描。
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165.发明授权公开(公告)号：US07072045B2
公开(公告)日：2006-07-04
申请号：US10345671
申请日：2003-01-16
Applicant: Zhongping Chen , Zhihua Ding , J. Stuart Nelson
Inventor： Zhongping Chen , Zhihua Ding , J. Stuart Nelson
IPC: G01B9/02
CPC classification number: G01B9/02027 , G01B9/0201 , G01B9/02035 , G01B9/02045 , G01B9/0205 , G01B9/02091 , G01B2290/70
Abstract: In optical coherence tomography (OCT), Axial and lateral resolutions are determined by the source coherence length and numerical aperture of the sampling lens, respectively. While axial resolution can be improved using a broadband light source, there is a trade-off between lateral resolution and focusing depth when conventional optical elements are used. The incorporation of an axicon lens into the sample arm of the interferometer overcomes this limitation. Using an axicon lens with a top angle of 160 degrees, 10 μm or better-lateral resolution is maintained over a focusing depth of at least 6 mm. In addition to high lateral resolution, the focusing spot intensity is approximately constant over a greater depth range.
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Patent Agency Ranking
公开(公告)号：US20060132790A1
公开(公告)日：2006-06-22
申请号：US10546421
申请日：2004-02-17
Applicant: Mikhail Gutin
Inventor： Mikhail Gutin
IPC: G01B9/02
CPC classification number: G01B9/02007 , A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/411 , A61B5/7203 , A61B5/7257 , G01B9/02002 , G01B9/0201 , G01B9/02012 , G01B9/02027 , G01B9/02034 , G01B9/02091 , G01B2290/65 , G01N21/45 , G01N21/4795 , G01N2021/1787 , G01N2021/458 , G01N2021/4709 , G01N2021/4742 , G01N2201/0691 , G01N2201/08
Abstract: Optical coherence tomography with 3D coherence scanning is disclosed, using at least three fibers (201, 202, 203) for object illumination and collection of backscattered light. Fiber tips (1, 2, 3) are located in a fiber tip plane (71) normal to the optical axis (72). Light beams emerging from the fibers overlap at an object (122) plane, a subset of intersections of the beams with the plane defining field of view (266) of the optical coherence tomography apparatus. Interference of light emitted and collected by the fibers creates a 3D fringe pattern. The 3D fringe pattern is scanned dynamically over the object by phase shift delays (102, 104) controlled remotely, near ends of the fibers opposite the tips of the fibers, and combined with light modulation. The dynamic fringe pattern is backscattered by the object, transmitted to a light processing system (108) such as a photo detector, and produces an AC signal on the output of the light processing system (108). Phase demodulation of the AC signal at selected frequencies and signal processing produce a measurement of a 3D profile of the object.
Abstract translation: 公开了具有3D相干扫描的光学相干断层摄影，使用至少三个光纤（201,202,203）进行物体照明和收集后向散射光。 光纤尖端（1,2,3）位于垂直于光轴（72）的纤维末端平面（71）中。 从光纤出射的光束在对象（122）平面处重叠，光束与定义光学相干断层摄影装置的视场（266）的平面的交点的子集重叠。 由纤维发出和收集的光的干涉产生3D条纹图案。 通过远程控制的相移延迟（102,104）在物体上动态扫描3D条纹图案，纤维的近端与光纤的尖端相反，并与光调制组合。 动态条纹图案被物体反向散射，传输到诸如光电检测器的光处理系统（108），并且在光处理系统（108）的输出上产生AC信号。 所选频率的AC信号的相位解调和信号处理产生对象的3D轮廓的测量。
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公开(公告)号：US07016048B2
公开(公告)日：2006-03-21
申请号：US10410723
申请日：2003-04-09
Applicant: Zhongping Chen , J. Stuart Nelson
Inventor： Zhongping Chen , J. Stuart Nelson
IPC: G01B9/02
CPC classification number: A61B5/0066 , A61B5/0073 , A61B5/0261 , A61B5/411 , A61B5/445 , G01B9/0201 , G01B9/02011 , G01B9/02027 , G01B9/02045 , G01B9/02069 , G01B9/02087 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01N21/4795
Abstract: A phase-resolved functional optical coherence tomography system simultaneously obtains the Stokes vectors, structure, blood flow velocity, standard deviation, and birefringence images in human skin. The multifunctional images were obtained by processing the analytical interference fringe signals derived from the two perpendicular polarization detection channels. The blood flow velocity and standard deviation images were obtained by comparing the phase from the pairs of analytical signals in the neighboring A-lines in the same polarization state. The Stokes vectors were obtained by processing the analytical signals from two polarization diversity detection channels for the same reference polarization state. From the four Stokes vectors, the birefringence image, which is insensitive to the orientations of the optical axis in the sample, was obtained. Multifunctional images of a port wine stain birthmark in human skin are demonstrated.
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公开(公告)号：US06985232B2
公开(公告)日：2006-01-10
申请号：US10387772
申请日：2003-03-13
Applicant: Abdurrahman Sezginer
Inventor： Abdurrahman Sezginer
IPC: G01B9/02
CPC classification number: G01B9/0201 , G01B9/02044 , G01B9/02069 , G01B9/02088 , G01B9/0209 , G01B11/0675 , G01B2210/56 , G01B2290/70 , G01J3/453
Abstract: A phase-sensitive interferometeric broadband reflectometer includes an illumination source for generating an optical beam. A beam splitter or other optical element splits the optical beam into probe beam and reference beam portions. The probe beam is reflected by a subject under test and then rejoined with the reference beam. The combination of the two beams creates an interference pattern that may be modulated by changing the length of the path traveled by the probe or reference beams. The combined beam is received and analyzed by a spectrometer.
Abstract translation: 相敏型干涉仪宽带反射计包括用于产生光束的照明源。 分束器或其他光学元件将光束分成探测光束和参考光束部分。 探测光束被被测物体反射，然后用参考光束重新连接。 两个光束的组合产生干涉图案，其可以通过改变由探针或参考光束行进的路径的长度来调制。 组合光束由光谱仪接收和分析。
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公开(公告)号：US20050243327A1
公开(公告)日：2005-11-03
申请号：US11160948
申请日：2005-07-16
Applicant: Chian Chiu Li
Inventor： Chian Chiu Li
CPC classification number: A61B5/0066 , A61B5/0059 , G01B9/0201 , G01B9/02019 , G01B9/02057 , G01B9/0209 , G01B9/02091 , G01B11/2441 , G01N21/49
Abstract: In a compact optical device, a light emitting area of a light source and a light sensing area of a detector are placed in proximity. The detector receives part of a beam which is reflected back to the source from a sample. As a result, a beam splitter is no longer needed. By eliminating the beam splitter and packing the light source and detector in closeness, dimensions of the optical device are reduced.
Abstract translation: 在紧凑的光学装置中，将光源的发光区域和检测器的感光区域放置在邻近处。 检测器接收从样品反射回源的一部分光束。 结果，不再需要分束器。 通过消除光束分离器并将光源和检测器封闭，光学装置的尺寸减小。
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公开(公告)号：US06927860B2
公开(公告)日：2005-08-09
申请号：US10440397
申请日：2003-05-19
Applicant: Adrian Gh. Podoleanu , David A. Jackson , John A. Rogers , George M. Dobre , Radu G. Cucu
Inventor： Adrian Gh. Podoleanu , David A. Jackson , John A. Rogers , George M. Dobre , Radu G. Cucu
CPC classification number: A61B3/102 , A61B5/0066 , G01B9/0201 , G01B9/02027 , G01B9/0203 , G01B9/02058 , G01B9/02063 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01N21/23 , G01N21/4795
Abstract: OCT apparatus includes an interferometer, having an input beam splitter and a 50/50 output splitter. The splitting ratio of the input splitter may be optimized depending on the source power of light source and on the mismatch of the balanced receiver. The input splitter is a plate beam-splitter to minimize the stray reflected light in the interferometer and allow sequential operation of the apparatus in the OCT or in the confocal regime. The switching between the two regimes may be at will, or synchronous with the en-face scanning which results in quasi-simultaneous OCT/confocal imaging or in alternatives frames, confocal and OCT. By using polarization sensitive elements, two channels are provided in each regime, OCT and confocal. The two confocal polarization sensitive channels may allow adjustments of compensators prior to OCT measurements or OCT imaging.
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