公开(公告)号：US20140111804A1

公开(公告)日：2014-04-24

申请号：US14008495

申请日：2011-03-28

Applicant: Ruediger Maestle

Inventor： Ruediger Maestle

IPC: G01J3/447

CPC classification number: G01J3/447 ,  G01J3/28 ,  H04B10/61 ,  H04B10/613 ,  H04B10/614 ,  H04B10/64

Abstract: A heterodyne optical spectrum analyzer (10) is configured for analyzing spectral information of an optical input signal (15). The analyzer (10) comprises a local oscillator source (20) configured for generating an optical local oscillator signal (38). An optical mixer (25) is configured for receiving the input signal (15) and the local oscillator signal (38), and for outputting a plurality of different combined optical signals (50), each combined optical signal (50) being derived from the input signal (15) and the local oscillator signal (38). An opto-electrical receiver (30) having a plurality of inputs (52) is configured for receiving the combined optical signals (50) and for providing an opto-electrical conversion thereof, and an output (54) for outputting electrical signals representing the received combined optical signals (50). A signal processor (35) is configured for deriving spectral information of the input signal (15) by analyzing the electrical signals. The optical mixer (25) is configured for deriving a plurality of polarization diverse signals from the input signal (15), each polarization diverse signal having a different state of polarization, and deriving a set of balanced quadrature signals for each polarization diverse signal by combining each polarization diverse signal with a signal derived from the local oscillator signal (38). The derived sets of balanced quadrature signals represent the plurality of combined optical signals (50).

Abstract translation: 外差光谱分析仪（10）被配置用于分析光输入信号（15）的光谱信息。 分析器（10）包括配置用于产生光本地振荡器信号（38）的本地振荡器源（20）。 光混合器（25）被配置为接收输入信号（15）和本地振荡器信号（38），并且用于输出多个不同的组合光信号（50），每个组合光信号（50）从 输入信号（15）和本地振荡器信号（38）。 具有多个输入（52）的光电接收器（30）被配置为用于接收组合的光信号（50）并用于提供其光电转换，以及输出（54），用于输出表示所接收的电信号 组合光信号（50）。 信号处理器（35）被配置为通过分析电信号来导出输入信号（15）的频谱信息。 光混合器（25）被配置为从输入信号（15）导出多个偏振分集信号，每个极化分集信号具有不同的偏振状态，并通过组合导出用于每个偏振分集信号的一组平衡正交信号 每个极化不同信号具有从本地振荡器信号（38）导出的信号。 导出的平衡正交信号组表示多个组合光信号（50）。

公开(公告)号：US20130258334A1

公开(公告)日：2013-10-03

申请号：US13851984

申请日：2013-03-28

Applicant: JASCO CORPORATION

Inventor： Tetsuji Sunami ,  Jun Koshoubu

IPC: G01J3/447

CPC classification number: G01J3/447 ,  G01J3/0208 ,  G01J3/0237 ,  G01N21/19

Abstract: A circular dichroism (CD) spectrometer includes an alignment mechanism that automatically adjusts the elements thereof at appropriate positions. The spectrometer has a focusing-lens position-and-orientation adjustment mechanism which adjusts the position and the orientation of the detector-side focusing lens. It also has a detector rotation mechanism which adjusts the orientation of the detector. Firstly, a control PC monitors the CD spectrum of D form of optical enantiomers, and the adjustment mechanism adjusts the focusing lens such that the monitored CD spectrum matches the reference spectrum related to the D form. Next, the control PC moniters CD spectrum of L form of optical enantiomers, and the adjustment mechanism adjusts the focusing lens such that the monitored CD spectrum of the D and L forms become symmetrical. And, the rotation mechanism adjusts the orientation of the detector such that the intensity of the detector signal is maximized.

Abstract translation: 圆形二色性（CD）光谱仪包括在适当位置自动调整元件的对准机构。 光谱仪具有调整检测器侧聚焦透镜的位置和取向的聚焦透镜位置和取向调节机构。 它还具有调节检测器方向的检测器旋转机构。 首先，控制PC监视D型光学对映体的CD光谱，并且调节机构调节聚焦透镜，使得所监视的CD光谱与D形式相关的参考光谱相匹配。 接下来，控制PC监视L型光学对映异构体的CD光谱，并且调节机构调节聚焦透镜，使得D和L形式的所监视的CD光谱变得对称。 并且，旋转机构调节检测器的方向，使得检测器信号的强度最大化。

公开(公告)号：US08514392B1

公开(公告)日：2013-08-20

申请号：US12683154

申请日：2010-01-06

Applicant: Arthur H. Carrieri ,  Jack Copper ,  David J. Owens ,  Erik S. Roese ,  Jerold R. Bottiger ,  Kevin C. Hung

Inventor： Arthur H. Carrieri ,  Jack Copper ,  David J. Owens ,  Erik S. Roese ,  Jerold R. Bottiger ,  Kevin C. Hung

IPC: G01J3/447

CPC classification number: G01J3/447 ,  G01J4/04 ,  G01N21/21 ,  G01N21/3504

Abstract: A system, apparatus, and method of generating Stokes vectors, a Mueller matrix, and polarized scattering from an aerosol aggregate includes providing an incident infrared laser beam; causing the incident infrared laser beam to be polarization-modulated using variable stress/strain birefringence imposed on a ZnSe crystal; defining a Stokes vector associated with the incident infrared laser beam; scattering the incident infrared laser beam from an aggregate aerosol comprising interferents and analyte particles; producing a scattered-beam reactant Stokes vector by causing the scattered incident infrared laser beam to be polarization-modulated; generating a Mueller matrix by taking a transformation of the Stokes vector; and identifying the analyte using the Mueller matrix. The Mueller matrix may comprise M-elements that are functions of a wavelength of the infrared laser beam, backsattering orientation of the infrared laser beam, and a shape and size of the interferents and analyte particles.

Abstract translation: 产生斯托克斯矢量，米勒矩阵和来自气溶胶聚集体的极化散射的系统，装置和方法包括提供入射的红外激光束; 使入射红外激光束使用施加在ZnSe晶体上的可变应力/应变双折射进行偏振调制; 定义与入射的红外激光束相关联的斯托克斯矢量; 从包含干扰物和分析物颗粒的聚集气溶胶散射入射的红外激光束; 通过使散射入射的红外激光束进行偏振调制，产生散射光束反应物斯托克斯矢量; 通过采用斯托克斯向量的变换来生成米勒矩阵; 并使用Mueller矩阵识别分析物。 Mueller矩阵可以包括作为红外激光束的波长，红外激光束的后向散射取向以及干扰物和分析物颗粒的形状和大小的功能的M元件。

公开(公告)号：US08374685B2

公开(公告)日：2013-02-12

申请号：US12529552

申请日：2008-03-07

Applicant: Antonius Theodorus Martinus Van Gogh ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Hans Zou ,  Maarten Marinus Johannes Wilhelmus Van Herpen

Inventor： Antonius Theodorus Martinus Van Gogh ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Hans Zou ,  Maarten Marinus Johannes Wilhelmus Van Herpen

IPC: A61B6/08 ,  G01J4/00 ,  G01J3/447 ,  G01N21/47

CPC classification number: A61B5/0075 ,  A61B5/0084 ,  G01N21/4795 ,  G01N2021/4792

Abstract: A system (40) for diagnosis and staging of early stages of cancer in the tissue of a patient is provided. The system—is configured to combine information from a Polarized Light Scattering Spectroscopy measurement (70) having a first probe depth, and a Differential Path Length Spectroscopy measurement (60) having a second probe depth, wherein the second probe depth is set larger than' the first probe depth. By comparing the results of the Polarized Light Scattering Spectroscopy and Differential Path Length Spectroscopy measurements early stages of cancer, such as dysplasia may be detected. Also hyperplasia, carcinoma in situ, and carcinoma may be detected. A computer-readable medium, method and use are also provided.

Abstract translation: 提供了一种用于诊断和分期患者组织中癌症早期阶段的系统（40）。 该系统被配置为组合来自具有第一探测深度的偏振光散射光谱测量（70）和具有第二探测深度的差分路径长度光谱测量（60）的信息，其中第二探测深度被设置为大于“ 第一探测深度。 通过比较极化光散射光谱和差分路径长度光谱测量的结果，可以检测癌症的早期阶段，例如发育异常。 也可能检测到增生，原位癌和癌。 还提供了计算机可读介质，方法和用途。

公开(公告)号：US20120327414A1

公开(公告)日：2012-12-27

申请号：US13494949

申请日：2012-06-12

Applicant: James Jianguo Xu ,  Ken Kinsun Lee ,  Rusmin Kudinar ,  Ronny Soetarman ,  Hung Phi Nguyen ,  Zhen Hou

Inventor： James Jianguo Xu ,  Ken Kinsun Lee ,  Rusmin Kudinar ,  Ronny Soetarman ,  Hung Phi Nguyen ,  Zhen Hou

IPC: G01J3/42 ,  G01J3/447

CPC classification number: G01J3/2823 ,  G01J3/0208 ,  G01J3/0218 ,  G01N21/274 ,  G01N21/55 ,  G02B21/0092

Abstract: A measurement system for monitoring an LED chip surface roughening process is described. A reflective illuminator can run reflectance measurements. A vertical positioning means can adjust a distance between an objective lens and an industrial sample. A horizontal positioning means can move objects in XY plane, and is specifically configured to hold the industrial sample and a reference sample. An optical sensor can acquire images of the industrial sample. A spectrometer can acquire reflectance spectrums of the industrial sample and the reference sample. A processor can control these components. The processor can perform deskew, and calculate an average reflectance and an oscillation amplitude from the reflectance spectrums of the industrial sample.

Abstract translation: 描述了一种用于监测LED芯片表面粗糙化工艺的测量系统。 反射照明器可以进行反射测量。 垂直定位装置可以调节物镜和工业样品之间的距离。 水平定位装置可以在XY平面中移动物体，并且被特别地配置成保持工业样品和参考样品。 光学传感器可以获取工业样品的图像。 光谱仪可以获得工业样品和参考样品的反射光谱。 处理器可以控制这些组件。 处理器可以进行偏斜校正，并从工业样品的反射光谱计算平均反射率和振荡幅度。

公开(公告)号：US08314935B2

公开(公告)日：2012-11-20

申请号：US12672067

申请日：2008-09-25

Applicant: Yoichiro Handa ,  Tomohiro Yamada

Inventor： Yoichiro Handa ,  Tomohiro Yamada

IPC: G01J3/447 ,  G01N21/55

CPC classification number: G01N21/554 ,  B82Y15/00 ,  B82Y20/00

Abstract: A target substance-detecting apparatus for detecting a target substance in an analyte comprises a detecting device having a substrate and metal structures capable of causing a plasmon resonance arranged thereon, an illumination optical system for illuminating an incident light containing a polarization component polarized in a first direction onto the detecting device to cross the arranged metal structures, a light-receiving device for receiving light containing the polarization component polarized in the first direction and transmitted through or reflected by the detecting device, and an arithmetic unit for calculating on signals from the light-receiving device to analyze a characteristic of the analyte; the metal structures arranged at first intervals not more than 1/10 of a plasmon resonance wavelength in lines in the first direction and at second intervals not less than ¼ of the plasmon resonance wavelength and not more than the wavelength in lines parallel in a second direction.

Abstract translation: 用于检测分析物中的目标物质的目标物质检测装置包括具有基板的检测装置和能够引起其上排列的等离子体共振的金属结构，照明光学系统，用于照射包含第一 方向移动到检测装置上以穿过排列的金属结构;光接收装置，用于接收包含在第一方向上偏振并被检测装置透射或反射的偏振分量的光，以及用于计算来自光的信号的运算单元 接收装置分析分析物的特征; 金属结构以第一方向排列的等离子体共振波长的1/10不等于等离子体共振波长的1/4以上的第一方向的第二间隔，并且不大于沿第二方向平行的波长的波长 。

公开(公告)号：US20120268740A1

公开(公告)日：2012-10-25

申请号：US13184619

申请日：2011-07-18

Applicant: Phillip Walsh ,  Anthony T. Hayes ,  Dale A. Harrison

Inventor： Phillip Walsh ,  Anthony T. Hayes ,  Dale A. Harrison

IPC: G01J3/447

CPC classification number: G01N21/255 ,  G01N21/19 ,  G01N21/33 ,  G01N2021/335

Abstract: A highly efficient vacuum ultraviolet circular dichroism spectrometer is provided; the spectrometer suitable for laboratory use or for integration into a beam line at a synchrotron radiation facility. In one embodiment, a spectroscopic circular dichroism instrument is provided; the instrument configured so as to enable circular dichroism data to be simultaneously obtained for multiple wavelengths of light. The instrument may be further configured to operate in at least a portion of the vacuum ultraviolet wavelength region.

Abstract translation: 提供了一种高效的真空紫外圆二色光谱仪; 该光谱仪适用于实验室使用或用于在同步加速器辐射设备处集成到光束线中。 在一个实施例中，提供了一种光谱圆二色性仪器; 该仪器被配置为使得能够同时获得多个波长的光的圆二色性数据。 该仪器可以被进一步配置成在真空紫外波长区域的至少一部分中操作。

公开(公告)号：US20110058166A1

公开(公告)日：2011-03-10

申请号：US12667753

申请日：2008-07-30

Applicant: Koichiro Nakamura ,  Yuzo Sasaki ,  Kazuo Fujiura ,  Shogo Yagi

Inventor： Koichiro Nakamura ,  Yuzo Sasaki ,  Kazuo Fujiura ,  Shogo Yagi

IPC: G01J3/447 ,  G01J3/28

CPC classification number: G01J3/14 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/18 ,  G01J3/36 ,  G01J2003/064

Abstract: The present invention provides a small spectroscope that has a short response time. A spectroscope according to one embodiment of the present invention includes: a beam deflector that includes an electro-optic crystal, having an electro-optic effect, and paired electrodes used to apply an electric field inside the electro-optic crystal; spectroscopic means for dispersing light output by the beam deflector; and wavelength selection means for selecting light having an arbitrary wavelength from the light dispersed and output by the spectroscopic means.

Abstract translation: 本发明提供一种响应时间短的小型分光镜。 根据本发明的一个实施例的分光镜包括：光束偏转器，其包括具有电光效应的电光晶体，以及用于在电光晶体内施加电场的成对电极; 分光装置，用于分散由光束偏转器输出的光; 以及波长选择装置，用于从由分光装置分散和输出的光中选择具有任意波长的光。

公开(公告)号：US20100282969A1

公开(公告)日：2010-11-11

申请号：US11969889

申请日：2008-01-05

Applicant: David L. Frank ,  Rodney L. Clark

Inventor： David L. Frank ,  Rodney L. Clark

IPC: G01J3/447 ,  G01J5/02

CPC classification number: G01N21/171 ,  G01N21/21 ,  G01N21/27

Abstract: A chemical and biological sensor system (200) includes at least one micro-cantilever sensing element (202) and a mechanism for collecting aerosol, liquid, and solid particles, and depositing the particles as a film layer (146) on a stack (140) formed with the cantilever. The deposited particles include chemical or biological species to be analyzed. A polarized light (242) illuminates the stack (140) at a grazing incidence angle to a specific wavelength of light. The light is polarized in a plane parallel to the stack (140). The polarized light (242) heats the cantilever with different wavelengths of the light spectrum. Readout electronics detect movement of the cantilever (202) as a result of heat transfer from the light and provide spectral data signals corresponding to the detected movement. A spectral analyzer (840) analyzes the spectral data signals, compares spectral images of the materials present to spectral images of known materials, and identifies one or more chemical or biological species present.

Abstract translation: 化学和生物传感器系统（200）包括至少一个微悬臂传感元件（202）和用于收集气溶胶，液体和固体颗粒的机构，并将作为膜层（146）的颗粒沉积在堆叠（140）上 ）与悬臂形成。 沉积的颗粒包括待分析的化学或生物物质。 偏振光（242）以特定波长的光的掠入射角照射叠层（140）。 光在平行于堆叠（140）的平面中极化。 偏振光（242）加热具有不同波长的光谱的悬臂。 读出电子部件由于从光的热传递而检测悬臂（202）的移动，并提供对应于检测到的运动的光谱数据信号。 光谱分析仪（840）分析光谱数据信号，将存在的材料的光谱图像与已知材料的光谱图像进行比较，并识别存在的一种或多种化学或生物物质。

公开(公告)号：US20100277729A1

公开(公告)日：2010-11-04

申请号：US12662650

申请日：2010-04-27

Applicant: Hyun-Jong Kim ,  Chung-Sam Jun ,  Hwan-Shik Park

Inventor： Hyun-Jong Kim ,  Chung-Sam Jun ,  Hwan-Shik Park

IPC: G01J3/447 ,  F21V13/02

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0224 ,  G01N21/211 ,  G01N2021/213 ,  G01N2021/214

Abstract: A light focusing unit and a spectrum measuring apparatus having the same are provided. The light focusing unit includes a light source section configured to emit light, a light guiding section configured to guide the light emitted from the light source section along multiple parallel light incidence paths, and a light focusing section configured to direct the light from the guiding section to be incident on a test position of a sample at different incidence angles.

Abstract translation: 提供了一种聚光单元和具有该聚光单元的光谱测量装置。 光聚焦单元包括被配置为发光的光源部分，被配置为沿着多个平行的光入射路径引导从光源部分发射的光的导光部分和被配置为引导来自引导部分的光的光聚焦部分 以不同的入射角入射到样品的测试位置。