中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

943 records (took 0.015 seconds)

    Direct radioimmunoassay for antigens and their antibodies
    11.
    发明授权
    Direct radioimmunoassay for antigens and their antibodies 失效
    用于抗原及其抗体的直接放射免疫法

    公开(公告)号：US3867517A

    公开(公告)日：1975-02-18

    申请号：US21051071

    申请日：1971-12-21

    Applicant: ABBOTT LAB

    Inventor： LING CHUNG-MEI

    IPC: G01N33/543 ,  G01N33/576 ,  A61K27/04

    CPC classification number: G01N33/54306 ,  G01N33/576 ,  Y10S436/804 ,  Y10S436/82

    Abstract: A method for direct radioimmunoassay of antigens or their associated antibodies utilizing a coated test well comprising adding a serum to be tested for an antigen to test apparatus coated with its antibody; incubating the tubes for from 0.5 to 42 hours; aspirating the contents and washing the same with a TrisHCl and sodium azide mixture; adding purified I-125 labeled antibody into the tube and incubating for from 1 to 24 hours; aspirating and washing the contents; and counting the tube for I125 radiation. A similar assay for the antibody may be conducted utilizing an antigen coated tube and I-125 labeled antigen. The method for coating these tubes comprises adding the antigen or antibody solution in a Tris-HCl, sodium azide solution into a suitable test tube or well, incubating the tubes at room temperature from 6 to 72 hours, aspirating and washing the contents and storing at from between 2 and 25*C. until use.

    Abstract translation: 一种使用包被的测试孔直接放射免疫测定抗原或其相关抗体的方法，其包括将待测试的血清添加到用其抗体包被的测试仪器上; 孵育管0.5至42小时; 吸入内容物并用Tris-HCl和叠氮化钠混合物洗涤; 将纯化的I-125标记的抗体加入管中并孵育1至24小时; 吸取和洗涤内容物; 并计算I-125辐射管。 可以使用抗原包被的管和I-125标记的抗原来进行抗体的类似测定。 用于包被这些试管的方法包括将抗原或抗体溶液加入到Tris-HCl，叠氮化钠溶液中至合适的试管或孔中，在室温下孵育6至72小时，抽吸和洗涤内容物并储存在 从2到25℃直到使用。

    Flow through tissue culture propagator
    15.
    发明授权
    Flow through tissue culture propagator 失效
    通过组织文化传播器流动

    公开(公告)号：US3843454A

    公开(公告)日：1974-10-22

    申请号：US27661672

    申请日：1972-07-31

    Applicant: ABBOTT LAB

    Inventor： WEISS R

    IPC: C12M3/04 ,  C12B1/04

    CPC classification number: C12M25/06 ,  C12M41/26 ,  C12M41/34

    Abstract: 1. AN APPARATUS FOR PROPAGATING TISSUE CULTURE CELLS COMPRISING A VESSEL ADAPTED FOR HOLDING LIQUID CULTURE MEDIUM, SAID VESSEL HAVING A PAIR OF OPPOSITE VERTICAL WALLS OF OPPOSITE ENDS OF A FIRST HORIZONTAL DIMENSION THEREOF AND A PLURALITY OF VERTICAL WALLS TRANSVERSE TO SAID OPPOSITE VERTICAL WALLS, AND VESSEL HAVING DISPOSED THEREIN A PLURALITY OF STACKED, SPACED-APART PLATES FORMED BY A CONTINUOUS STRIP OF UNDULATED MATERIAL AND ADAPTED TO PROVIDE SURFACES TO WHICH CELL GROWTH CAN ATTACH, SAID PLATES EACH SPACED FROM SAID PAIR OF OPPOSITE VERTICAL WALLS OF SAID VESSEL TO THEREBY FORM FIRST AND SECOND VERTICAL CHANNELS WITHIN SAID VESSEL AT SAID OPPOSITE ENDS OF SAID FIRST HORIZONTAL DIMENSION THEREOF, AN INLET CONDUIT INTO SAID VESSEL OPENING DIRECTLY INTO SAID FIRST VERTICAL CHANNEL; AND AN OUTLET CONDUIT FROM SAID VESSEL EXITING DIRECTLY FORM SAID SECOND VERTICAL CHANNEL.

    Urethane catalyst
    18.
    发明授权
    Urethane catalyst 失效
    URETHANE催化剂

    公开(公告)号：US3816339A

    公开(公告)日：1974-06-11

    申请号：US22823772

    申请日：1972-02-22

    Applicant: ABBOTT LAB

    Inventor： RADEN D

    IPC: C08G18/18 ,  C08G22/38

    CPC classification number: C08G18/1816

    Abstract: A new catalyst for the acceleration of urethane polymerization consisting of a mixture of N,N-dimethyl-cyclohexyl-amine and Nmethyl-dicyclohexylamine has been found. The new mixture has unique characteristics that are not expected from its components taken alone.

    Tetrapeptide
    19.
    发明授权
    Tetrapeptide 失效
    四分之一

    公开(公告)号：US3803117A

    公开(公告)日：1974-04-09

    申请号：US23794172

    申请日：1972-03-24

    Applicant: ABBOTT LAB

    Inventor： FLOURET G

    IPC: C07K5/103 ,  C07C103/52

    CPC classification number: C07K5/101 ,  Y10S514/80 ,  Y10S930/13

    Abstract: THE NEW BLOCKED TETRAPEPTIDE Y-LEU-(N$:R'') ARG-PROGLY-R WHEREIN R IS HYDROXY, METHOXY OR AMINO, R'' IS A SUITABLE BLOCKING GROUP AND Y IS HYDROGEN OR AN EASILY REMOVABLE PROTECTIVE GROUP HAS BEEN FOUND TO BE A VALUABLE INTTERMEDIATE FOR THE PREPARATION OF LARGE PEPTIDE CHAINS, SUCH AS FOR ISTANCE, THE DECAPEPTIDE GN-RH.

    Octapeptide derivative of gonadotropinreleasing hormone
    20.
    发明授权
    Octapeptide derivative of gonadotropinreleasing hormone 失效
    角蛋白衍生物衍生物

    公开(公告)号：US3790555A

    公开(公告)日：1974-02-05

    申请号：US3790555D

    申请日：1972-01-20

    Applicant: ABBOTT LAB

    Inventor： FLOURET G ,  COLE J

    IPC: C07K7/23 ,  C07C103/52 ,  C07G7/00 ,  C08H1/00

    CPC classification number: C07K7/23 ,  Y10S930/13

    Abstract: THE SYNTHESIS OF THE OCTAPEPTIDE TRP-SER-TYR-GLY-LEUARG-PRO-GLY-AMIDE CARRYING EASILY REMOVABLE PROTECTIVE GROUPS ON THE SER, TYR, ARG AND TRP MOIETIES IS DESCRIBED. THE NEW SYNTHESIS USES AS THE STARTING MATERIAL TWO TETRAPEPTIDE FRAGMENTS CARRYING EASILY REMOVABLE PROTECTIVE GROUPS. ONE OF THESE FRAGMENTS, TRP-SER-TYR-GLY-OH WITH SUITABLE PROTECTIVE GROUPS, ALSO IS A PART OF THE PRESENT INVENTION. AFTER COUPLING OF THE TWO FRAGMENTS, THE PROTECTIVE GROUP ON THE AMINO-N OF THE TRYPTOPHANE MOIETY IS REMOVED TO OBTAIN AN OCTAPEPTIDE CARRYING EASILY REMOVABLE PROTECTIVE GROUPS WHICH CAN BE RETAINED VHILE BULIDING UP THE MOLECULE TO THE DECAPEPTIDE CHAIN WHICH IS THE GONADOTROPIN-RELEASING HORMONE, AFTER REMOVAL OF THESE PROTECTIVE GROUPS.

Patent Agency Ranking