公开(公告)号：US3831103A

公开(公告)日：1974-08-20

申请号：US35589073

申请日：1973-04-30

Applicant: BECKMAN INSTRUMENTS INC

Inventor： RUEGG F ,  SILVA L

IPC: H03H11/12 ,  H03F1/36

CPC classification number: H03H11/1295

Abstract: An active element sharp cut-off bandpass filter circuit having independently tunable center frequency and Q characteristics. The filter circuit incorporates a high performance operational amplifier having one input connected to ground and a pair of feedback paths interconnecting the amplifier output and the other input. One feedback path includes two capacitors connected in series and the other path includes two resistors connected in series. The input to the filter circuit is connected, via an input resistor, to the common juncture of the capacitors; and the amplifier output is connected to the filter output terminal, as well as to one end of a grounded voltage divider having a movable tap. The common juncture of the feedback resistors is connected, via a capacitor, to the movable tap of the voltage divider. In one embodiment the capacitors have equal values and the feedback resistors have values which are four times the value of the input resistor.

Abstract translation: 具有独立可调的中心频率和Q特性的有源元件尖锐截止带通滤波器电路。 滤波器电路包括具有连接到地的一个输入的高性能运算放大器和互连放大器输出和另一个输入的一对反馈路径。 一个反馈路径包括串联连接的两个电容器，另一路径包括串联连接的两个电阻器。 滤波电路的输入通过输入电阻连接到电容器的公共接点; 并且放大器输出连接到滤波器输出端子，以及连接到具有可移动分接头的接地分压器的一端。 反馈电阻的共同接点通过电容器连接到分压器的可移动抽头。 在一个实施例中，电容器具有相等的值，并且反馈电阻器的值是输入电阻器值的四倍。

公开(公告)号：US3826821A

公开(公告)日：1974-07-30

申请号：US11206271

申请日：1971-02-02

Applicant: BECKMAN INSTRUMENTS INC

Inventor： ZICHIS J

IPC: G01N33/569 ,  G01N31/00 ,  G01N31/02 ,  G01N33/16

CPC classification number: G01N33/56983

Abstract: SHEEP OR HORSE BLOOD IS SPECIALLY TREATED TO PRODUCE AN ANTIGEN WHICH IS READILY AGGLUTINABLE BY HETEROPHIL TYPE ANTIBODIES PRESENT IN THE PATIENTS SCRUM. THE ANTIGEN POSSESSES PROPERTIES OF STABILITY, SENSITIVITY AND AGGLUTINABILITY WHICH ARE UTILIZED IN A SEROLOGICAL DIAGNOSTIC TEST FOR INFECTIOUS MONONUCLEOSIS. TWO OTHER ANTIGENS, PREPARED FROM BEEF BLOOD AND FROM GUINEA PIG TISSUES, ARE USED IN THE TEST TO DIFFERENTIATE THE INFECTIOUS MONONUCLEOSIS TYPE ANTIBODY FROM THE FORSSMAN TYPE.

公开(公告)号：US3814957A

公开(公告)日：1974-06-04

申请号：US33497773

申请日：1973-02-22

Applicant: BECKMAN INSTRUMENTS INC

Inventor： WAY A

IPC: G05D23/24 ,  H03K17/00

CPC classification number: G05D23/24 ,  G05D23/1913

Abstract: A precision temperature controller utilizing a temperature sensitive resistive element in thermal relationship to an object to be heated, the element being connected in a bridge circuit to derive an error signal proportional to deviation from a desired temperature, the error signal being summed with a sawtooth voltage, the output so obtained being compared with a reference voltage in an operational amplifier to derive a pulsed output having a pulse width proportional to the error signal, the pulse width being used to control the time duration of energization of a heating element in proximity to the resistive element.

Abstract translation: 一种精密温度控制器，利用与待加热物体热关系的温度敏感电阻元件，该元件在桥接电路中连接以导出与偏离期望温度成比例的误差信号，误差信号与锯齿波电压相加 ，所得到的输出与运算放大器中的参考电压进行比较，以得到具有与误差信号成比例的脉冲宽度的脉冲输出，该脉冲宽度用于控制加热元件靠近的加热元件的通电持续时间 电阻元件。

公开(公告)号：US3801179A

公开(公告)日：1974-04-02

申请号：US3801179D

申请日：1968-01-02

Applicant: BECKMAN INSTRUMENTS INC

Inventor： WISSE J ,  VAN ES W

IPC: G02B5/24 ,  F21V9/06

CPC classification number: G02B5/24

Abstract: A narrow band-pass ultraviolet filter for continuous determination of protein consisting essentially of a first component (e.g., a concentrated solution of nickel sulfate and cobalt sulfate or red-purple ''''Corex'''' A glass) for absorbing substantially, or otherwise eliminating from consideration, all incident light in the visible region of the spectrum and a part of the light in the ultraviolet region of the spectrum, a second component (e.g., a concentrated solution of a heavy metal salt plus an acid addition salt of 2,7-dimethyl-3,6-diazacyclo-1,6heptadiene) which is a filter component for absorbing a substantial part of the light in the near ultraviolet region of the spectrum, and a separate third component for absorbing light of wavelengths below 260 millimicrons and a greater part of the light above 340 millimicrons, the separate third component consisting essentially of a complex compound of one or more metals (viz., Cr, Mn, Fe, Co, Ni, Cu or rare earth) and one or more chelating agents selected from the group consisting of ethylene-diaminotetra-acetic acid, iminodiacetic acid, nitrilotriacetic acid, diamines, and condensation products of diamines and carbonyl compounds. Components in solution form are enclosed in cells, the walls of which are transparent to ultraviolet light.

Abstract translation: 用于连续测定蛋白质的窄带通紫外线过滤器，其基本上由第一组分（例如硫酸镍和硫酸钴或红紫色“Corex”A玻璃）的浓缩溶液组成，用于基本上或以其他方式消除考虑， 在光谱的可见光区域中的所有入射光和光谱的紫外区域中的一部分光，第二组分（例如，重金属盐的加浓溶液加上2,7-二甲基 - 3,6-二氮杂环戊烯-1,6-庚二烯），其是用于吸收光谱的近紫外区域中的大部分光的过滤器组分，以及用于吸收低于260毫微米的波长的光的单独的第三组分 340毫微克以上的部分光，分离的第三组分基本上由一种或多种金属（即Cr，Mn，Fe，Co，Ni，Cu或稀土）的络合物和一种或多种螯合a 选自乙烯 - 二氨基四乙酸，亚氨基二乙酸，次氮基三乙酸，二胺，以及二胺和羰基化合物的缩合产物。 溶液形式的组分被包封在细胞中，其壁对紫外线是透明的。

公开(公告)号：US3788815A

公开(公告)日：1974-01-29

申请号：US3788815D

申请日：1972-03-02

Applicant: BECKMAN INSTRUMENTS INC

Inventor： ROHRBAUGH D

IPC: B01L3/14 ,  G01N1/10 ,  G01N1/14

CPC classification number: B01L3/5082

Abstract: AN ELONGATED SAMPLE SOLUTION CUP HAS A CROSS SECTION ADAPTED TO INDUCING TURBULENCE IN A SOLVENT STIRRED IN THE CUP, AND HAS AN OFFSET RECESSED BOTTOM CAVITY PROVIDING A LOCALIZED DISSOLVER VOLUME FOR SOLID SAMPLES INTRODUCED INTO THE CUP. A REMOVABLE FILTER TUBE PROVIDES A FILTERED SAMPLE SOLUTION FOR FURTHER WET ANALYSIS. THE REACTOR MODULE COMPRISING THE SOLUTION CUP AND THE REMOVABLE FILTER TUBE IS MADE OF A THIN WALL THERMOPLASTIC MATERIAL, SUITABLE FOR USING ONE OR MORE TIMES.

公开(公告)号：US3787291A

公开(公告)日：1974-01-22

申请号：US3787291D

申请日：1971-11-29

Applicant: BECKMAN INSTRUMENTS INC

Inventor： DEURINGER R ,  RAY R ,  STERNBERG J

IPC: G01N31/00 ,  G01N33/487 ,  G01N35/00 ,  G01N35/10 ,  C12K1/10

CPC classification number: G01N35/00 ,  G01N2035/00534 ,  G01N2035/1025

Abstract: An apparatus for batch analysis of liquid samples wherein syringes are employed for delivering repeatable volumes of reagent to a cell prior to the addition of a sample and for withdrawing liquid from the cell after analysis thereof. Sensing means, such as a polarographic oxygen sensor, is mounted in the side wall of the cell with it sensing end contacting the liquid therein. A stirring element is positioned within the cell and rotated about the vertical axis of the cell so that a high tangential stirring force is produced to promote mixing of sample with reagent and to optimize sensor performance, yet only small sample volumes are required. The apparatus is particularly suited for rate sensing batch analysis of biological fluids such as blood or urine.

Abstract translation: 用于液体样品的批量分析的装置，其中使用注射器在加入样品之前将可重复体积的试剂递送到细胞，并在分析之后从细胞中取出液体。 诸如极谱氧传感器的感测装置安装在电池的侧壁中，其感测端与其中的液体接触。 搅拌元件位于电池内并围绕电池的垂直轴线旋转，从而产生高切向搅拌力以促进样品与试剂的混合并优化传感器性能，但仅需要较小的样品体积。 该装置特别适用于生物流体如血液或尿液的速率检测批次分析。

公开(公告)号：US3786465A

公开(公告)日：1974-01-15

申请号：US3786465D

申请日：1972-04-17

Applicant: BECKMAN INSTRUMENTS INC

Inventor： WOODS T

IPC: G01D1/10 ,  C12M1/34 ,  C12Q1/00 ,  G01N21/27 ,  G01N21/75 ,  G01N27/00 ,  G01N27/06 ,  G01N27/416 ,  G01N33/48 ,  G01N33/483 ,  G08B21/00

CPC classification number: G01N21/272

Abstract: A rate analysis instrumentation system including a sample cell and detector for producing an electrical cell signal proportional to a parameter of a sample reacting within the cell. In a preferred embodiment the enzyme activity of a sample is measured by detecting the light absorbance characteristics of the sample. A differentiator is utilized to obtain a rate signal from the light absorbance characteristic, and the rate signal is displayed. A constant rate detection circuit is used to measure the rate signal only during periods when the reaction rate and the cell signal are linear. The constant rate detection circuit differentiates the rate signal whereby a second derivative of the cell signal is provided. The second derivative signal is compared in a comparator to a threshold value to determine when the second derivative signal approaches zero. An overrange protection circuit is provided for excluding false rate signals, such as signals having characteristics that fail to meet predetermined acceptable limits.

Abstract translation: 一种速率分析仪器系统，包括用于产生与在所述电池内反应的样品的参数成比例的电池信号的样品池和检测器。 在优选的实施方案中，通过检测样品的吸光度特性来测量样品的酶活性。 利用微分器从光吸收特性获得速率信号，并显示速率信号。 恒定速率检测电路仅在反应速率和电池信号为线性的期间用于测量速率信号。 恒定速率检测电路区分速率信号，从而提供单元信号的二阶导数。 将二进制信号在比较器中与阈值进行比较，以确定二阶导数信号何时接近零。 提供超范围保护电路用于排除诸如具有不能达到预定可接受限度的特性的信号的错误率信号。

公开(公告)号：US3780238A

公开(公告)日：1973-12-18

申请号：US3780238D

申请日：1971-12-27

Applicant: BECKMAN INSTRUMENTS INC

Inventor： BRANT R ,  SHEPARD S

IPC: H01H19/64 ,  H01H21/78 ,  H05K1/07

CPC classification number: H01H19/64

Abstract: A carrier and terminal connector for a nonconductive circuit module in the form of a thin wafer having oppositely disposed flat surfaces and an electrical cicuit network deposited on at least one surface thereof including terminal pads positioned along at least one edge thereof. The carrier, terminal connector and non-conductive circuit module are used in a multi-sectional rotary wafer switch assembly. A conductive rotor engages printed circuit terminal paths disposed on the face of the circuit module.

Abstract translation: 一种用于非导电电路模块的载体和端子连接器，其为具有相对设置的平坦表面的薄晶片形式，以及沉积在其至少一个表面上的电气网络网络，其包括沿其至少一个边缘定位的端子焊盘。 载体，端子连接器和非导电电路模块用于多截面旋转晶片开关组件中。 导电转子接合设置在电路模块的表面上的印刷电路端子路径。

公开(公告)号：US3767881A

公开(公告)日：1973-10-23

申请号：US3767881D

申请日：1972-03-06

Applicant: BECKMAN INSTRUMENTS INC

Inventor： SHARPLES T

IPC: H01H13/18 ,  H01H3/04

CPC classification number: H01H13/186

Abstract: A switch having an operating lever provided with support ears pivotably retained in pivot-bearing holes formed in bearing projections on the switch case. An elastomeric filling is provided between each support ear and its corresponding bearing hole whereby torsional pivot bearings are provided for the operating lever. In one embodiment the elastomeric filling is bonded to the support ears and to the inner surfaces of the bearing holes. The elastomeric filling can comprise any suitable elastomer such as RTV silicone or urethane based rubber.

Abstract translation: 一种具有操作杆的开关，该操作杆设置有可旋转地保持在形成在开关壳体上的轴承突起中的枢转轴承孔中的支撑耳。 在每个支撑耳与其相应的轴承孔之间提供弹性体填充物，由此为操作杆提供扭转枢转轴承。 在一个实施例中，弹性填充物结合到支撑耳和轴承孔的内表面。 弹性体填充物可以包括任何合适的弹性体，例如RTV硅树脂或聚氨酯基橡胶。

公开(公告)号：US3765841A

公开(公告)日：1973-10-16

申请号：US3765841D

申请日：1971-08-06

Applicant: BECKMAN INSTRUMENTS INC

Inventor： PAULSON G ,  RAY R

IPC: G01N27/06 ,  C12M1/34 ,  G01N27/26 ,  G01N33/487 ,  G01N33/62 ,  C12K1/10 ,  G01N33/16

CPC classification number: G01N27/3271 ,  Y10T436/171538

Abstract: A method and apparatus for determining the concentration of a component in a sample, i.e. the concentration of urea in biological fluids, such as blood serum, wherein the sample, upon being introduced into solution with a reagent, reacts therewith, causing a continuing change in a characteristic of the solution, and wherein the rate of the reaction is indicative of the concentration of the component in the sample. A sensor is provided for monitoring the characteristic of the solution and for generating a first electrical output signal proportional thereto. Differentiator circuit means are provided for producing a second electrical signal proportional to the time derivative of the first signal, the time derivative signal being indicative of the concentration of the component in the sample.

Abstract translation: 用于确定样品中组分浓度的方法和装置，即生物流体如血清中的尿素浓度，其中样品在被试剂引入溶液中与其反应时，导致持续变化 溶液的特征，并且其中反应速率指示样品中组分的浓度。 提供传感器用于监测溶液的特性并产生与其成比例的第一电输出信号。 提供微分电路装置用于产生与第一信号的时间导数成比例的第二电信号，时间导数信号表示样品中组分的浓度。