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    Process for cathodic protection of electrode materials
    11.
    发明授权
    Process for cathodic protection of electrode materials 有权
    电极材料阴极保护工艺

    公开(公告)号：US07691252B2

    公开(公告)日：2010-04-06

    申请号：US11881254

    申请日：2007-07-26

    Applicant: Dao Min Zhou ,  Amy Hines ,  James Singleton Little ,  Robert J. Greenberg

    Inventor： Dao Min Zhou ,  Amy Hines ,  James Singleton Little ,  Robert J. Greenberg

    IPC: C23F13/04

    CPC classification number: C23F13/00 ,  A61N1/05 ,  A61N1/08 ,  C23F13/02

    Abstract: The present invention relates to a process for cathodic protection of electrode or electrode materials wherein negative bias is applied on the electrode. the negative bias is obtained by asymmetric current pulse. The asymmetric current pulse is obtained by performing negative phase with higher amplitude. The asymmetric current pulse is obtained by performing negative phase with wider pulse width than that of the anodic phase. The asymmetric current pulse is obtained by performing negative phase with higher amplitude and with wider pulse width than that of the anodic phase. The present invention further relates to a process for cathodic protection of electrode or electrode materials, wherein negative bias is applied on the electrode, wherein the negative bias is obtained by asymmetric current pulse, wherein the asymmetric current pulse is obtained by performing negative phase with wider pulse width than that of the anodic phase. The wider pulse width is obtained by pulse trains.

    Abstract translation: 本发明涉及对电极或电极材料进行阴极保护的方法，其中负电极施加在电极上。 负偏压通过不对称电流脉冲获得。 通过执行具有较高振幅的负相来获得非对称电流脉冲。 通过执行具有比阳极相宽的脉冲宽度的负相来获得非对称电流脉冲。 通过执行具有更高幅度和宽于脉冲宽度的阳极相的负相位获得非对称电流脉冲。 本发明还涉及一种用于对电极或电极材料进行阴极保护的方法，其中在电极上施加负偏压，其中通过不对称电流脉冲获得负偏压，其中非对称电流脉冲通过执行具有更宽的负相 脉冲宽度大于阳极相。 通过脉冲串获得更宽的脉冲宽度。

    Simply Supported Neural Stimulation Electrode Array for Applying Pressure on Neural Tissue
    12.
    发明申请
    Simply Supported Neural Stimulation Electrode Array for Applying Pressure on Neural Tissue 审中-公开
    用于神经组织施加压力的简单支持的神经刺激电极阵列

    公开(公告)号：US20090270958A1

    公开(公告)日：2009-10-29

    申请号：US12429890

    申请日：2009-04-24

    Applicant: Robert J. Greenberg ,  Mohamed Khaldi ,  James Singleton Little ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot

    Inventor： Robert J. Greenberg ,  Mohamed Khaldi ,  James Singleton Little ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot

    IPC: A61N1/05

    CPC classification number: A61N1/0543 ,  A61N1/36046

    Abstract: The present invention is an electrode array for neural stimulation suitable to be attached to neural tissue such that the attachment point acts as a fulcrum like point and contact with an end of the array body presses the other end of the array body into the neural tissue to be stimulated. This invention is particularly useful in a retinal electrode array for a visual prosthesis. By curving an electrode portion of an array body to approximate but not exceed (never more tightly curved) the curvature of the retina and applying force to the array by external means at the fulcrum like point, approximately even pressure across all electrodes is achieved.

    Abstract translation: 本发明是一种用于神经刺激的电极阵列，其适用于附着于神经组织，使得附着点作为支点，并且与阵列体的端部接触将阵列体的另一端压入神经组织， 被刺激。 本发明在用于视觉假体的视网膜电极阵列中特别有用。 通过将阵列体的电极部分弯曲成近似但不超过（从不更紧密地弯曲）视网膜的曲率并且通过外部装置在支点点处向阵列施加力，实现了跨所有电极的大致均匀的压力。

    FLEXIBLE CIRCUIT ELECTRODE ARRAY
    13.
    发明申请
    FLEXIBLE CIRCUIT ELECTRODE ARRAY 审中-公开
    柔性电路阵列

    公开(公告)号：US20080221653A1

    公开(公告)日：2008-09-11

    申请号：US12044830

    申请日：2008-03-07

    Applicant: Rajat Agrawal ,  Robert J. Greenberg ,  Mark S. Humayun ,  James Singleton Little ,  Brian V. Mech ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot ,  Dao Min Zhou

    Inventor： Rajat Agrawal ,  Robert J. Greenberg ,  Mark S. Humayun ,  James Singleton Little ,  Brian V. Mech ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot ,  Dao Min Zhou

    IPC: A61N1/00

    CPC classification number: A61N1/05 ,  A61N1/0541 ,  A61N1/0543 ,  A61N1/36046

    Abstract: A flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a central opening in the area of the metal traces. A flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a soft polymer filling an attachment point. A flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a hump to avoid a touching of the flexible electrode array and the optic nerve.

    Abstract translation: 一种柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层; 和金属痕迹区域的中心开口。 一种柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层; 和填充附着点的软质聚合物。 一种柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层; 和一个驼峰以避免触摸柔性电极阵列和视神经。

    Flexible circuit electrode array device and a method for backside processing of a flexible circuit electrode device
    16.
    发明授权
    Flexible circuit electrode array device and a method for backside processing of a flexible circuit electrode device 有权
    柔性电路电极阵列器件及柔性电路电极器件的背面处理方法

    公开(公告)号：US08738149B2

    公开(公告)日：2014-05-27

    申请号：US13397604

    申请日：2012-02-15

    Applicant: Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

    Inventor： Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

    IPC: A61N1/04

    CPC classification number: A61N1/05 ,  A61N1/0541 ,  A61N1/0543 ,  B23K26/361 ,  B23K26/362

    Abstract: The invention involves a flexible circuit electrode array device comprising: a polymer layer; wherein the polymer layer includes one or more metal traces, an electrode array; one or more bond pads; and the electrode array is located on the opposite side of the polymer layer.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: applying polymer film on a substrate; processing the front side; releasing the polymer film from substrate; flipping over the polymer film and fixing it onto the substrate; processing the backside; and final releasing of the polymer film from the substrate.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: processing the front side without releasing the polymer; processing the backside by sacrificial substrate method, or by laser drilling method; and releasing the polymer film from the substrate.

    Abstract translation: 本发明涉及一种柔性电路电极阵列器件，包括：聚合物层; 其中所述聚合物层包括一个或多个金属迹线，电极阵列; 一个或多个接合垫; 并且电极阵列位于聚合物层的相对侧上。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：在基底上施加聚合物膜; 正面加工; 从基材中释放聚合物膜; 翻转在聚合物膜上并将其固定在基底上; 处理背面; 并从基底中最终释放聚合物膜。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：处理前侧而不释放聚合物; 通过牺牲基板方法或通过激光钻孔方法处理背面; 并从基板上释放聚合物膜。

    Electrode with increased stability and method of manufacturing the same
    18.
    发明授权
    Electrode with increased stability and method of manufacturing the same 有权
    增加稳定性的电极及其制造方法

    公开(公告)号：US07937153B2

    公开(公告)日：2011-05-03

    申请号：US11820744

    申请日：2007-06-19

    Applicant: Dao Min Zhou ,  Jerry Ok ,  Neil Hamilton Talbot ,  Brian V. Mech ,  James Singleton Little ,  Robert J. Greenberg

    Inventor： Dao Min Zhou ,  Jerry Ok ,  Neil Hamilton Talbot ,  Brian V. Mech ,  James Singleton Little ,  Robert J. Greenberg

    IPC: A61N1/00

    CPC classification number: A61N1/0543 ,  A61N1/36046

    Abstract: An implantable electrode with increased stability having a clustered structure wherein the surface of the electrode is covered with a material comprising openings which are filled with sticks or posts. An implantable electrode with increased stability wherein the surface is of the electrode comprises mesh grids which are filled with sticks which are filed with a conducting or insulating material. A method of manufacturing an electrode with increased stability, comprising: depositing a metal layer on an base layer; applying photoresist layer on the metal layer; patterning the photoresist layer providing openings; electroplating the openings with metal; removing the photoresist layer leaving spaces; and filling the spaces with polymer. A method of manufacturing an electrode with increased stability, comprising: depositing a metal layer on an base layer; applying a polymer layer on the metal layer; applying photoresist layer on the polymer layer; patterning the photoresist layer providing openings; electroplating the openings with metal; and removing the photoresist layer.

    Abstract translation: 具有增加的稳定性的可植入电极具有聚集结构，其中电极的表面被包括充满棒或柱的开口的材料覆盖。 具有增加的稳定性的可植入电极，其中电极的表面包括填充有用导电或绝缘材料填充的棒的网状网格。 一种制造具有增加的稳定性的电极的方法，包括：在基底层上沉积金属层; 在金属层上施加光致抗蚀剂层; 图案化提供开口的光致抗蚀剂层; 用金属电镀开口; 去除留下空间的光致抗蚀剂层; 并用聚合物填充空间。 一种制造具有增加的稳定性的电极的方法，包括：在基底层上沉积金属层; 在金属层上施加聚合物层; 在聚合物层上施加光致抗蚀剂层; 图案化提供开口的光致抗蚀剂层; 用金属电镀开口; 并除去光致抗蚀剂层。

    Flexible Circuit Electrode Array
    20.
    发明申请
    Flexible Circuit Electrode Array 有权
    柔性电路电极阵列

    公开(公告)号：US20090264972A1

    公开(公告)日：2009-10-22

    申请号：US12163658

    申请日：2008-06-27

    Applicant: David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Boon-Khai Ng ,  James Singleton Little

    Inventor： David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Boon-Khai Ng ,  James Singleton Little

    IPC: A61N1/05 ,  B29C70/88 ,  B05D5/12

    CPC classification number: A61N1/0543 ,  A61N1/0541 ,  H05K1/036 ,  H05K1/0393 ,  H05K1/118 ,  H05K3/28 ,  H05K2201/0133 ,  H05K2201/0195 ,  Y10T156/1002

    Abstract: A flexible circuit electrode array, which comprises: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a partial or entire coating of the base and top layer by a soft polymer.A method of preparing a flexible circuit electrode array, comprising: (a) providing a first soft polymer layer; (b) depositing a first a base layer on the first soft polymer layer; (c) providing a metal thin film on the base layer; (d) depositing a top polymer layer on the metal thin film; (e) providing holes in the top polymer layer; (f) depositing a second soft polymer layer on the top polymer layer; (g) providing holes in the second soft polymer layer for bond pads and electrodes; and (h) preparing electrodes in the provided holes.A method of preparing a flexible circuit electrode array, comprising: (a) providing a first soft polymer layer; (b) depositing a first a base layer on the first soft polymer layer; (c) providing a metal thin film on the base layer; (d) depositing a top polymer layer on the metal thin film; (e) depositing a second soft polymer layer on the top polymer layer; (f) providing holes in the second soft polymer layer and in the top polymer layer for bond pads and electrodes; and (g) preparing electrodes in the provided holes.

    Abstract translation: 一种柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层; 以及通过软聚合物的基底和顶层的部分或全部涂层。 一种制备柔性电路电极阵列的方法，包括：（a）提供第一软聚合物层; （b）在第一软聚合物层上沉积第一基底层; （c）在基层上提供金属薄膜; （d）在金属薄膜上沉积顶部聚合物层; （e）在顶部聚合物层中提供孔; （f）在顶部聚合物层上沉积第二软聚合物层; （g）在第二软聚合物层中为接合焊盘和电极提供孔; 和（h）在所提供的孔中制备电极。 一种制备柔性电路电极阵列的方法，包括：（a）提供第一软聚合物层; （b）在第一软聚合物层上沉积第一基底层; （c）在基层上提供金属薄膜; （d）在金属薄膜上沉积顶部聚合物层; （e）在顶部聚合物层上沉积第二软聚合物层; （f）在第二软聚合物层和顶部聚合物层中提供用于接合焊盘和电极的孔; 和（g）在所提供的孔中制备电极。

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