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11.
公开(公告)号:US12276046B2
公开(公告)日:2025-04-15
申请号:US18453224
申请日:2023-08-21
Applicant: Purdue Research Foundation
Inventor: Mukerrem Cakmak
IPC: B29C39/14 , B29C39/18 , B29C41/28 , B29C59/04 , B32B27/00 , D01D5/00 , B05C5/00 , B05C5/02 , B05C11/04 , B29C59/02 , B82Y40/00
Abstract: A roll-to-roll manufacturing machine suitable for processing and producing polymer films that contain nanostructures, including but not limited to multifunctional polymer films. The machine applies a liquid polymer on a substrate to form a liquid polymer film, at least partially embeds nanostructures into the liquid polymer film, melt casts a layer of a molten polymer on the liquid polymer film to produce a thin polymer film, organizes the nanostructures in a thickness direction of the thin polymer film comprising applying an electric field to the thin polymer film, aligns the nanostructures in the thin polymer film by simultaneously subjecting the thin polymer film to heat and a field that aligns the nanostructures, and solidifies the thin polymer film to freeze the nanostructures along nanocolumns in a thickness direction of a solidified polymer film resulting therefrom.
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公开(公告)号:US12274682B2
公开(公告)日:2025-04-15
申请号:US18046917
申请日:2022-10-15
Applicant: Purdue Research Foundation
Inventor: Kee-Hong Kim , Yuyan Zhu
IPC: A61K31/18 , A61K31/167 , A61P3/04 , A61P3/06 , A61P3/10 , C12N15/113
Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.
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公开(公告)号:US12269908B2
公开(公告)日:2025-04-08
申请号:US17787190
申请日:2020-12-17
Applicant: Purdue Research Foundation
Inventor: Jonathan J. Wilker , Samuel L. Huntington , Amelia A. Putnam
IPC: C08F212/08 , C08F212/14
Abstract: This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure.
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公开(公告)号:US12269862B2
公开(公告)日:2025-04-08
申请号:US18459302
申请日:2023-08-31
Applicant: PURDUE RESEARCH FOUNDATION , ENDOCYTE, INC. , SEATTLE CHILDREN'S HOSPITAL
Inventor: Philip Stewart Low , Haiyan Chu , Yingjuan June Lu , Christopher Paul Leamon , Leroy W. Wheeler, II , Michael C. Jensen , James Matthaei
IPC: C07K14/725 , A61K9/00 , A61K31/365 , A61K31/519 , A61K38/17 , A61K39/00 , A61P35/00 , C07K16/44 , C07K16/46 , C12N5/0783
Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
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公开(公告)号:US20250107925A1
公开(公告)日:2025-04-03
申请号:US18725571
申请日:2023-01-05
Inventor: Nam-Joon CHO , Subra SURESH , Chi Hwan LEE , Youngkyu HWANG , Min Ku KIM
Abstract: Disclosed herein is a conductive composite material, comprising a pollen-based substrate layer, an elastomeric adhesive layer on top of the pollen-based substrate layer, a biocompatible polymer substrate layer on top of the elastomeric adhesive layer, and a metal layer on top of the biocompatible polymer substrate layer and a method of forming the same. Also disclosed herein is a stretchable biopolymer-based heating pad comprising a pollen-based substrate layer, a cured polymeric layer or a metal layer on top of the pollen-based substrate layer, where, when present, the cured polymeric layer comprises a cured polymeric material and a metal, an encapsulation coating comprising a polymeric material that encapsulates the cured polymeric layer or the metal layer, wherein the pollen-based substrate layer and the cured polymeric layer are patterned to provide a heating pad and the method of forming the same.
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16.
公开(公告)号:US20250102528A1
公开(公告)日:2025-03-27
申请号:US18728868
申请日:2023-01-13
Applicant: Daniel Silva ANTONELO , Julio Cesar BALIEIRO , PURDUE RESEARCH FOUNDATION , UNIVERSITY OF SAO PAULO
Abstract: Method of assessing biomarkers of a cattle carcass indicative of a characteristic of the animal such as finishing regimen or ultimate pH of the muscles of the animal, and kits to facilitate performing the method.
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公开(公告)号:US20250091943A1
公开(公告)日:2025-03-20
申请号:US18885107
申请日:2024-09-13
Applicant: Purdue Research Foundation
Inventor: Maria Mirian Velay Lizancos , John E. Haddock , Pablo Orosa Iglesias , Manuel Uriel Aspilcueta Asencios
IPC: C04B14/02 , C04B26/26 , C04B103/00 , C04B111/00 , C04B111/94
Abstract: The electrically conductive pavement system includes a cold recycled asphalt mixture and a carbon black material. The carbon black material is mixed with the cold recycled asphalt mixture. The pavement system is configured to be heated. For instance, the pavement system includes a heating element and an electrical power source. The heating element may couple the electrical power source to the pavement system. In a more specific example, the heating element may include an electrical probe that include an electrically conductive cable or wire. The electrically conductive cable or wire may be selectively heated when the electrical power source is engaged. Once heated, the pavement system may have faster curing times and enhanced compaction over known pavements. The heating functionality also permits self-healing capabilities for more efficient repairs and enhanced durability. The heating functionality may also be utilized to melt ice and/or snow from a surface of the pavement system.
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公开(公告)号:US12253545B2
公开(公告)日:2025-03-18
申请号:US17779480
申请日:2020-11-24
Applicant: Purdue Research Foundation
Inventor: Kaushik Roy , Byunghoo Jung , Chamika Mihiranga Liyanagedera
Abstract: System and methods for high accuracy, non-intrusive current sensing are provided. A system may include two magnetic field sensors configured for differential sensing. The system may further include frontend circuitry configured to remove direct current (DC) offset of the magnetic field sensors, upconvert the outputs of the magnetic field sensors, and filter out at least one frequency component from the up-converted signals. The system may receive output signals from the front-end circuitry corresponding to each sensor. The system may further calculate a differential signal based on the output signals. The system may apply optimal detection based on the differential signal and a reference signal to calculate a measurement of current flow. The system may determine a phase angle measurement between the differential signal and the reference signal to calculate a direction of the current flow in the conductor and output various measurement information related to the detected current.
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公开(公告)号:US12250869B2
公开(公告)日:2025-03-11
申请号:US18527201
申请日:2023-12-01
Applicant: Purdue Research Foundation
Inventor: Letian Dou , Blake Peter Finkenauer
IPC: H10K85/10 , H10K85/40 , H10K30/10 , H10K102/00 , H10K102/10
Abstract: A perovskite-polymer composite comprising a perovskite and a polymer, wherein the polymer has a structural unit comprising a thiourea (—HN(C═S)NH—) fragment and a (—R1—O—R2—) fragment, wherein R1 and R2 are each independently a C1-C6 alkyl or a cycloalkyl linker; a mechanically robust and self-healable solar cell comprising same; and a method of making same.
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公开(公告)号:US20250073479A1
公开(公告)日:2025-03-06
申请号:US18951518
申请日:2024-11-18
Applicant: Purdue Research Foundation
Inventor: Shreyas Sen , Baibhab Chatterjee , Mayukh Nath
Abstract: A system and method for brain-machine interface communication utilizing Bi-Phasic Quasi-Static Brain Communication (BP-QBC). The system includes a first device and a second device that are in wireless communication together. The system and method include signal transmission between the first device and the second device through dipole coupling. The system is configured to utilize compressive sensing and collision avoidance for enhanced net energy efficiency. The system and method utilize fully electrical quasi-static signaling to militate against energy transduction losses.
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