公开(公告)号：US20190057866A1

公开(公告)日：2019-02-21

申请号：US16106931

申请日：2018-08-21

Applicant: FLOSFIA INC. ,  NATIONAL INSTITUTE FOR MATERIALS SCIENCE ,  KYOTO UNIVERSITY ,  SAGA UNIVERSITY

Inventor： Yuichi OSHIMA ,  Shizuo FUJITA ,  Kentaro KANEKO ,  Makoto KASU ,  Katsuaki KAWARA ,  Takashi SHINOHE ,  Tokiyoshi MATSUDA ,  Toshimi HITORA

IPC: H01L21/02 ,  H01L29/24 ,  C30B25/04 ,  C30B25/18 ,  C30B29/20

Abstract: According to an aspect of a present inventive subject matter, a crystal includes: a corundum-structured oxide semiconductor as a major component, the corundum-structured oxide semiconductor including gallium and/or indium and doped with a dopant including germanium; a principal plane; a carrier concentration that is 1×1018/cm3 or more; and an electron mobility that is 20 cm2/Vs or more.

公开(公告)号：US09976968B2

公开(公告)日：2018-05-22

申请号：US15030209

申请日：2014-10-17

Applicant: Saga University ,  Nagasaki University

Inventor： Yukihiro Ito ,  Kazuhisa Shiki ,  Hiroshi Matsuda ,  Akira Demizu

IPC: G01N21/956 ,  G01N21/88 ,  G01N25/72 ,  G01L5/00 ,  H05B6/02 ,  H05B6/36

CPC classification number: G01N21/956 ,  G01L5/00 ,  G01N21/8851 ,  G01N25/72 ,  G01N2021/8893 ,  H05B6/02 ,  H05B6/36

Abstract: There is provided a crack detection system in which a crack can be detected from a strain distribution of a part to be detected of an object. After taking the image of the part to be detected of the detection object by the imaging unit, the heat is applied by the heating unit. Furthermore, image of the part to be detected are taken again and an image analysis unit analyzes the images before and after applying the heat to acquire a strain distribution of the part to be detected, so that the crack can be detected based on difference in a state of strain between a place where the crack exist and the other place. Therefore, taking the images of the part to be detected including its coating layer enables the analysis to progress without removing the coating layer to detect the crack.

公开(公告)号：US09945263B2

公开(公告)日：2018-04-17

申请号：US14201406

申请日：2014-03-07

Applicant: Saga University

Inventor： Yasuyuki Ikegami ,  Sadayuki Jitsuhara ,  Taro Watanabe ,  Shin Okamura

IPC: F01K7/12 ,  F01K23/02 ,  F01K25/10 ,  F28B1/02 ,  F28D1/02 ,  F28D1/03 ,  F28D21/00 ,  F01K7/16

CPC classification number: F01K7/16 ,  F01K23/02 ,  F01K25/106 ,  F28B1/02 ,  F28D1/022 ,  F28D1/0316 ,  F28D2021/0063 ,  F28D2021/0064 ,  F28F2250/106

Abstract: There is provided a steam power cycle system in which steam power cycles using pure materials as a working fluid is used in a multiple stage to reduce pressure loss in the flow channels in the respective heat exchanger so that the fluid serving as heat sources has been caused to make an effective heat exchange with the working fluid. More specifically, not only that the respective flow channels for the fluid serving as heat sources in the evaporator and the condenser in the respective steam power cycle units are connected in series to each other, but the evaporator and the condenser comprise a cross-flow type heat exchanger and are arranged respectively in a flowing direction of the fluid serving as heat source. Consequently, it is possible to reduce the length of the flow channels to the minimum necessary, simplify the flow channel structure, and reduce the pressure loss.

公开(公告)号：US20160340736A1

公开(公告)日：2016-11-24

申请号：US15108159

申请日：2014-12-25

Applicant: SAGA UNIVERSITY ,  ARKRAY, Inc.

Inventor： Naoko Aragane ,  Shinya Kimura ,  Naomi Watanabe

IPC: C12Q1/68 ,  G01N33/574

CPC classification number: C12Q1/6886 ,  C07K14/70596 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/57423 ,  G01N2333/70596 ,  G01N2333/912

Abstract: Provided is a lung cancer biomarker containing a DDR2 protein or a DDR2 gene, or a mutant thereof, i.e., the following (a), (b) and (c): (a) overexpressed DDR2 protein or DDR2 gene; (b) overexpressed DDR2 protein or DDR2 gene mutant; and (c) DDR2 protein or DDR2 gene mutant.

Abstract translation: 本发明提供了含有DDR2蛋白或DDR2基因或其突变体的肺癌生物标志物，即以下（a），（b）和（c）：（a）过表达的DDR2蛋白或DDR2基因; （b）过表达的DDR2蛋白或DDR2基因突变体; 和（c）DDR2蛋白或DDR2基因突变体。

公开(公告)号：US09328634B2

公开(公告)日：2016-05-03

申请号：US14182022

申请日：2014-02-17

Applicant: Saga University

Inventor： Yasuyuki Ikegami ,  Takafumi Morisaki

IPC: F01K25/06 ,  F01K25/08 ,  F01K25/10 ,  F28B7/00 ,  F01B1/00 ,  F01K7/38

CPC classification number: F01K25/065 ,  F01K7/38 ,  F01K25/06 ,  Y02E10/34

Abstract: There is provided a steam power cycle system that permits to perform an appropriate heat exchange between a working fluid that is a non-azeotropic mixture and a heat source, to enhance the performance of the whole system. More specifically, a plurality of condensers are provided so as to be connected to each other in series, and the working fluid in a gas phase from the expander is introduced into the respective condensers. Consequently, the ratio of a low boiling point substance of the working fluid becomes higher toward the posterior condenser, it is possible to make the condensation temperature of the working fluid lower than that of the anterior condenser. It is therefore possible to make the temperature of the working fluid possibly close to the temperature of the low-temperature fluid, thus permitting an effective use of the difference in temperature of the heat source.

Abstract translation: 提供了一种蒸汽动力循环系统，其允许在非共沸混合物的工作流体和热源之间进行适当的热交换，以增强整个系统的性能。 更具体地说，多个冷凝器被设置为彼此串联连接，并且来自膨胀器的气相中的工作流体被引入到各个冷凝器中。 因此，工作流体的低沸点物质的比例向后冷凝器变高，可以使工作流体的冷凝温度低于前冷凝器的冷凝温度。 因此，可以使工作流体的温度可能接近低温流体的温度，从而有效地利用热源的温度差。

公开(公告)号：US20160022870A1

公开(公告)日：2016-01-28

申请号：US14776101

申请日：2013-10-24

Applicant: SAGA UNIVERSITY ,  CYFUSE BIOMEDICAL K.K.

Inventor： Ryo NOGUCHI ,  Tadashi TAMURA ,  Koichi NAKAYAMA ,  Shigeki MORITA ,  Koichi NODE

IPC: A61L27/36 ,  A61K35/33 ,  A61K35/44 ,  A61K35/34

CPC classification number: A61L27/3625 ,  A61K35/33 ,  A61K35/34 ,  A61K35/44 ,  A61L27/3804 ,  A61L27/3886 ,  A61L27/507 ,  A61L2300/64 ,  A61L2430/20 ,  C12N5/0691 ,  C12N5/0697 ,  C12N2502/1323 ,  C12N2502/1329 ,  C12N2502/28

Abstract: Provided is a method for producing a cardiac tissue spheroid or vascular tissue spheroid formed from a mixture of a myocardial cell or smooth muscle cell and at least one type of cell selected from a vascular endothelial cell and fibroblast, and a three dimensional cardiac tissue structure or three dimensional vascular tissue structure which are characterized by combining or laminating said spheroid.

Abstract translation: 本发明提供一种由心肌细胞或平滑肌细胞和至少一种选自血管内皮细胞和成纤维细胞的细胞的混合物形成的心脏组织球状体或血管组织球形体的制造方法，以及三维心脏组织结构或 三维血管组织结构，其特征在于组合或层压所述球体。

公开(公告)号：US09114373B2

公开(公告)日：2015-08-25

申请号：US14274261

申请日：2014-05-09

Applicant: Saga University

Inventor： Tatsuya Misawa ,  Nobuya Hayashi

IPC: H01J17/26 ,  H01J61/28 ,  B01J19/08 ,  H05H1/24

CPC classification number: B01J19/088 ,  B01J19/08 ,  B01J2219/0809 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/2418

Abstract: There is provided a plasma generation device capable of suppressing arc discharge in which discharge is localized to cause a high temperature, and allowing atmospheric discharge plasma to be stably generated with a high generation efficiency in a low temperature at about a room temperature without being spatially biased. The plasma generation device arranged with a plurality of electrodes facing each other includes a discharge position control unit, which is arranged between each of the plurality of electrodes, and is formed by containing an inverse characteristic material composed of a fluid having polarizability and a property that dielectric constant decreases with an increase in temperature, in a container formed of a dielectric material, wherein the inverse characteristic material is spaced apart from each of the plurality of electrodes.

Abstract translation: 提供了一种能够抑制放电定位以产生高温的电弧放电的等离子体产生装置，并且在大约室温下在低温下以高发电效率稳定地产生大气放电等离子体，而不会被空间偏置 。 布置有彼此面对的多个电极的等离子体产生装置包括排出位置控制单元，其布置在多个电极中的每一个之间，并且由包含由具有极化性的流体构成的反向特性材料形成， 在由电介质材料形成的容器中，介电常数随着温度的升高而降低，其中反向特征材料与多个电极中的每一个间隔开。

公开(公告)号：US20140273280A1

公开(公告)日：2014-09-18

申请号：US14354355

申请日：2012-10-30

Applicant: SAGA UNIVERSITY ,  YAMAGATA UNIVERSITY

Inventor： Kenji Izuhara ,  Shoichiro Ohta ,  Kazuhiko Arima ,  Hiroshi Shiraishi ,  Shoichi Suzuki ,  Nobuo Ohta ,  Akihiro Ishida ,  Yusuke Suzuki

IPC: G01N33/53

CPC classification number: G01N33/5308 ,  G01N33/6893 ,  G01N2800/14 ,  G01N2800/7095

Abstract: The present invention provides a method for detecting chronic sinusitis, which comprises measuring the concentration of a periostin protein in blood or nasal secretion collected from a test subject. Thereby, a method for detecting chronic sinusitis, which is capable of detecting chronic sinusitis more simply, more promptly and less invasively, is provided.

Abstract translation: 本发明提供一种检测慢性鼻窦炎的方法，其包括测定从测试对象收集的血液或鼻分泌物中骨膜素蛋白的浓度。 因此，提供了能够更简单，更迅速，更少侵入地检测慢性鼻窦炎的慢性鼻窦炎检测方法。

公开(公告)号：US11667600B2

公开(公告)日：2023-06-06

申请号：US17042377

申请日：2019-03-29

Applicant: DAIKIN INDUSTRIES, LTD. ,  SAGA UNIVERSITY

Inventor： Masahiro Higashi ,  Yosuke Kishikawa ,  Tsugio Kitamura

IPC: C07C67/307 ,  C07C231/12 ,  C07C51/363 ,  C07C45/63 ,  C07C51/62 ,  C07C17/02

CPC classification number: C07C67/307 ,  C07C17/02 ,  C07C45/63 ,  C07C51/363 ,  C07C51/62 ,  C07C231/12 ,  C07C67/307 ,  C07C69/62 ,  C07C67/307 ,  C07C69/738

Abstract: An object of the present invention is to provide a method for producing a fluorinated organic compound, whereby an iodosylbenzene derivative can be easily separated and recovered. The above object can be achieved by a method for producing a fluorinated organic compound, comprising step A of fluorinating an organic compound (1) by reaction with a fluorine source (3) in the presence of a hypervalent iodine aromatic ring compound (2a), or in the presence of an iodine aromatic ring compound (2b) and an oxidant (2bo); wherein the fluorine source (3) is a fluorine source (3a) represented by formula: MFn, wherein M is H, a metal of Group 1 of the periodic table, or a metal of Group 2 of the periodic table; and n is 1 or 2; and step B of separating the iodine aromatic ring compound from a reaction liquid after step A is started.

公开(公告)号：US20230076858A1

公开(公告)日：2023-03-09

申请号：US17795821

申请日：2021-02-01

Applicant: KYOCERA CORPORATION ,  SAGA UNIVERSITY

Inventor： Kazuya MATSUNAGA ,  Fumiya NAKADA ,  Masaaki MAWATARI ,  Tadatsugu MORIMOTO

IPC: A61F2/44

Abstract: A spinal implant includes a base and a coating film disposed on the base and including a calcium phosphate-based material and an antimicrobial agent. A surface of the base includes a first region in which the coating film is disposed and a second region exposed from the coating film.