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公开(公告)号：US20240150781A1
公开(公告)日：2024-05-09
申请号：US18409598
申请日：2024-01-10
Applicant: Commonwealth Scientific and Industrial Research Organisation , GRAINS RESEARCH AND DEVELOPMENT CORPORATION
Inventor： James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
IPC: C12N15/82 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472
CPC classification number: C12N15/8247 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472 , C12Y602/01003
Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
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公开(公告)号：US11859193B2
公开(公告)日：2024-01-02
申请号：US16329939
申请日：2017-09-01
Inventor： XueRong Zhou , Qing Liu , Anna El Tahchy , Srinivas Belide , Madeline Claire Mitchell , Uday Kumar Divi , Thomas Vanhercke , James Robertson Petrie , Surinder Pal Singh , Allan Graham Green
IPC: C12N15/82 , C11B1/10 , A23K10/12 , A23K10/30 , C11C3/00 , C11B1/04 , C10L1/02 , C11B1/06 , C12Q1/6895
CPC classification number: C12N15/8247 , A23K10/12 , A23K10/30 , C10L1/026 , C11B1/04 , C11B1/06 , C11B1/10 , C11C3/003 , C12N15/8218 , C12N15/8251 , C12Q1/6895 , C10L2200/0476 , C10L2200/0484 , C10L2270/026 , C10L2290/04 , C10L2290/24 , C10L2290/26 , C12Q2600/13
Abstract: The present invention relates, inter alia, to vegetative plant parts, such as from a Sorghum sp. and/or a Zea mays plant, which comprise a total fatty acid (TFA) content which comprises fatty acids esterified in the form of triacylglycerols (TAG) and fatty acids in the form of lipids other than TAG, wherein the vegetative plant parts comprise greatly increased levels of TFA, for example a TFA content of about 5% (w/w dry weight). The present invention also relates to the use of the vegetative plant parts as a feedstuff, and/or to produce a feedstuff, for animal consumption.
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公开(公告)号：US11814600B2
公开(公告)日：2023-11-14
申请号：US17828322
申请日：2022-05-31
Inventor： Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Kyle Reynolds , Qing Liu , Benjamin Aldo Leita
IPC: C11B1/10 , C11B7/00 , C11C3/04 , C10L1/08 , C10L1/02 , C10G3/00 , C10B53/02 , C11C3/12 , C11B3/02 , C11C3/10 , C11B3/00 , C11C3/00
CPC classification number: C11B1/10 , C10B53/02 , C10G3/40 , C10L1/026 , C10L1/08 , C11B3/00 , C11B3/02 , C11B7/00 , C11C3/00 , C11C3/04 , C11C3/10 , C11C3/12 , C10L2200/0476 , C10L2270/026 , C10L2290/06 , C10L2290/26 , C10L2290/544 , Y02E50/10 , Y02P30/20
Abstract: The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biodiesel and synthetic diesel and processes for producing these, as well as plants having an increased level of one or more non-polar lipids such as triacylglycerols and an increased total non-polar lipid content. In one particular embodiment, the present invention relates to combinations of modifications in two or more of lipid handling enzymes, oil body proteins, decreased lipid catabolic enzymes and/or transcription factors regulating lipid biosynthesis to increase the level of one or more non-polar lipids and/or the total non-polar lipid content and/or mono-unsaturated fatty acid content in plants or any part thereof. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biodiesel fuel.
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公开(公告)号：US20190284567A1
公开(公告)日：2019-09-19
申请号：US16355215
申请日：2019-03-15
Inventor： Kyle B. Reynolds , Thomas Vanhercke , Anna El Tahchy , Qing Liu , Surinder S. Singh , James R. Petrie
Abstract: The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biofuel, and processes for producing these products, as well as plants having an increased level medium chain fatty acids such as lauric acid and myristic acid. In one particular embodiment, the present invention relates to combinations of modifications in a fatty acid thioesterase and one or more acyltransferases. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biofuel.
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公开(公告)号：US20190203125A1
公开(公告)日：2019-07-04
申请号：US16353639
申请日：2019-03-14
Inventor： Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C10B53/02 , C10L5/44 , C10G2/00 , C10L1/02 , C07K14/415 , C12N15/82 , C11B1/10 , C11B3/00 , C11B3/10 , C11B3/14 , C11B7/00 , C11C3/00 , C12N9/10 , C10J3/82 , C11B1/00 , C07C67/48 , C01B3/22 , C01B32/40 , C12P7/64
CPC classification number: C10B53/02 , C01B3/22 , C01B32/40 , C01B2203/1211 , C07C67/48 , C07K14/415 , C10G2/00 , C10G2/30 , C10J3/82 , C10J2300/0906 , C10J2300/0916 , C10J2300/1659 , C10J2300/1846 , C10L1/02 , C10L1/026 , C10L5/44 , C10L2200/0469 , C10L2200/0476 , C10L2200/0492 , C10L2270/026 , C10L2290/02 , C10L2290/04 , C10L2290/06 , C10L2290/26 , C10L2290/28 , C10L2290/30 , C10L2290/42 , C10L2290/544 , C11B1/00 , C11B1/10 , C11B3/001 , C11B3/006 , C11B3/10 , C11B3/14 , C11B7/0075 , C11C3/003 , C12N9/1051 , C12N15/8218 , C12N15/8247 , C12P7/6463 , C12Y204/01101 , Y02E20/16 , Y02E20/18 , Y02E50/10 , Y02E50/13 , Y02E50/14 , Y02E50/17 , Y02E50/30 , Y02E50/32 , Y02E50/343
Abstract: The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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Patent Agency Ranking
公开(公告)号：US09499829B2
公开(公告)日：2016-11-22
申请号：US14462323
申请日：2014-08-18
Inventor： Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C12N15/82 , A23K1/14 , C11B1/10 , C07K14/415 , C11B3/00 , C11B3/10 , C11B3/14 , C11B7/00 , C10L1/02 , C11C3/00 , C10G2/00 , C12P7/64 , C11B1/04 , C10L5/44
CPC classification number: C10L1/19 , A23K10/30 , A23K20/153 , C07K14/415 , C10G2/00 , C10L1/026 , C10L5/44 , C10L2200/0476 , C10L2290/24 , C10L2290/544 , C11B1/04 , C11B1/06 , C11B1/10 , C11B3/001 , C11B3/006 , C11B3/02 , C11B3/10 , C11B3/14 , C11B7/0008 , C11B7/0075 , C11C3/003 , C12N15/8218 , C12N15/8247 , C12P7/6463 , Y02E50/30 , Y02E50/343
Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
Abstract translation: 本发明涉及从营养植物部分如叶，茎，根和块茎中提取脂质的方法，以及从脂质生产工业产品如烃产品。 优选的工业产品包括可与石油基燃料混合的烷基酯。
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公开(公告)号：US12195739B2
公开(公告)日：2025-01-14
申请号：US18409591
申请日：2024-01-10
Applicant: Commonwealth Scientific and Industrial Research Organisation , GRAINS RESEARCH AND DEVELOPMENT CORPORATION
Inventor： James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
IPC: C12N15/82 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472
Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
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公开(公告)号：US20240150782A1
公开(公告)日：2024-05-09
申请号：US18409603
申请日：2024-01-10
Applicant: Commonwealth Scientific and Industrial Research Organisation , GRAINS RESEARCH AND DEVELOPMENT CORPORATION
Inventor： James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
IPC: C12N15/82 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472
CPC classification number: C12N15/8247 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472 , C12Y602/01003
Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 desaturases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
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公开(公告)号：US20230058089A1
公开(公告)日：2023-02-23
申请号：US17821539
申请日：2022-08-23
Inventor： Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C10B53/02 , C10L5/44 , C11B1/00 , C01B32/40 , C12P7/6463 , C11B1/10 , C11B3/00 , C11B3/10 , C11B3/14 , C11B7/00 , C11C3/00 , C07K14/415 , C12N15/82 , C10L1/02 , C10G2/00 , C10L1/19 , C07C67/48 , C01B3/22 , C10J3/82 , C12N9/10
Abstract: The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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公开(公告)号：US10925293B2
公开(公告)日：2021-02-23
申请号：US14834914
申请日：2015-08-25
Inventor： James Robertson Petrie , Thomas Vanhercke , Pushkar Shrestha , Qing Liu , Surinder Pal Singh
Abstract: The present invention relates to methods of producing lipids. In particular, the present invention relates to methods of increasing the level of one or more non-polar lipids and/or the total non-polar lipid content in a transgenic organism or part thereof. In one particular embodiment, the present invention relates to the use of an acyltransferase, for example, a monoacylglycerol acyltransferase (MGAT) to increase the level of one or more non-polar lipids and/or the total non-polar lipid content in plants, plant seed and/or leaves, algae and fungi.
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