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    METHOD AND SYSTEM FOR IMAGING AND COLLECTION OF DATA FOR DIAGNOSTIC PURPOSES
    11.
    发明申请
    METHOD AND SYSTEM FOR IMAGING AND COLLECTION OF DATA FOR DIAGNOSTIC PURPOSES 有权

    公开(公告)号：US20230000356A1

    公开(公告)日：2023-01-05

    申请号：US17856487

    申请日：2022-07-01

    Applicant: UNIVERSITY HEALTH NETWORK

    Inventor： Ralph Sebastian Dacosta ,  Brian C. Wilson ,  Kai Zhang

    IPC: A61B5/00 ,  G01N21/64 ,  A61B5/01

    Abstract: A system for outputting a representation of a wound in tissue comprises a housing configured to removably receive at least a portion of a wireless communication device. At least one light source coupled to the housing is configured to emit excitation light to illuminate a target which includes at least a portion of the wound. A power supply contained in the housing is configured to provide power to the light source. A non-transitory computer-readable medium stores a program executable to cause the performance of operations comprising detecting signals responsive to illumination of the target, outputting the representation of the target based thereon, storing data relative to one or more target surface parameter based on the detected signals, and displaying the representation. The signals correspond to at least one of endogenous or exogeneous fluorescence, absorbance, and reflectance from at least one biological component in and/or on the target.

    Devices, methods, and systems for fluorescence-based endoscopic imaging and collection of data with optical filters with corresponding discrete spectral bandwidth
    12.
    发明授权
    Devices, methods, and systems for fluorescence-based endoscopic imaging and collection of data with optical filters with corresponding discrete spectral bandwidth 有权

    公开(公告)号：US11284800B2

    公开(公告)日：2022-03-29

    申请号：US15965462

    申请日：2018-04-27

    Applicant: University Health Network

    Inventor： Ralph Dacosta ,  Brian C. Wilson ,  Kai Zhang

    IPC: A61B5/00 ,  A61B5/01 ,  G01N21/64 ,  A61B10/00

    Abstract: A portable, handheld device for fluorescence-based imaging is provided. The device comprises a wireless communication device having a sensor configured to detect optical signals. The device further comprises an assembly configured to receive and secure the wireless communication device therein. The assembly includes a housing, at least one light source coupled to the housing, a power supply, and an optical filter holder coupled to the housing and configured to receive one or more optical filters. An endoscope portion of the device is positioned relative to the sensor to visualize at least a portion of a confined anatomical space and to receive optical signals from a visualized, illuminated portion of a target positioned within the confined anatomical space. A processor of the device includes image analysis software and is configured to produce a composite representation of the illuminated portion of the target positioned within the confined anatomical space.

    Method and system for imaging and collection of data for diagnostic purposes
    15.
    发明授权
    Method and system for imaging and collection of data for diagnostic purposes 有权

    公开(公告)号：US11154198B2

    公开(公告)日：2021-10-26

    申请号：US16027775

    申请日：2018-07-05

    Applicant: UNIVERSITY HEALTH NETWORK

    Inventor： Ralph S. Dacosta ,  Brian C. Wilson ,  Kai Zhang

    IPC: A61B5/00 ,  G01N21/64 ,  A61B5/01 ,  A61B10/00

    Abstract: A system for fluorescence-based imaging of a target includes at least one excitation light source configured to emit a homogeneous field of excitation light and positioned to uniformly illuminate a target surface with the homogeneous field of excitation light during fluorescent imaging, a power source, and a portable housing configured to be held in a user's hand during imaging. The housing contains a lens, a filter, an image sensor, and a processor. The filter is configured to permit optical signals responsive to illumination of the target surface and having a wavelength corresponding to at least one of bacterial autofluorescence and tissue autofluorescence to pass through the filter to the image sensor. The at least one excitation light is adjacent to the housing so as to be positioned between the target surface and the image sensor during fluorescent imaging.

    DEVICES, METHODS, AND SYSTEMS FOR DETECTING AND IDENTIFYING BACTERIA BASED ON FLUORESCENCE SIGNATURE
    17.
    发明申请
    DEVICES, METHODS, AND SYSTEMS FOR DETECTING AND IDENTIFYING BACTERIA BASED ON FLUORESCENCE SIGNATURE 有权

    公开(公告)号：US20250160651A1

    公开(公告)日：2025-05-22

    申请号：US19027622

    申请日：2025-01-17

    Applicant: UNIVERSITY HEALTH NETWORK

    Inventor： Ralph Sebastian Dacosta ,  Brian C. Wilson ,  Kai Zhang

    IPC: A61B5/00 ,  A61B5/01 ,  A61B10/00 ,  G01N21/64

    Abstract: A system for acquiring data regarding a wound in tissue comprises at least one excitation light source configured to directly illuminate a wound with excitation light; a spectral filtering mechanism configured to permit passage of optical signals responsive to illumination of the wound and having at least one wavelength corresponding to bacterial, fungal, and/or other microorganism autofluorescence and/or bacterial, fungal, viral, and/or microbial fluorescence, the spectral filtering mechanism including a plurality of selectable filters respectively corresponding to different discrete spectral bandwidths; an optical sensor configured to detect the spectrally filtered signals; and a processor configured to receive the detected, filtered signals and to identify a fluorescent signature of bacteria in the wound based at least in part on the detected, filtered signals and to output data regarding the bacterial, fungal, viral, and/or microbial fluorescent signature.

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