公开(公告)号：US20250020681A1

公开(公告)日：2025-01-16

申请号：US18887119

申请日：2024-09-17

Applicant: VANRX PHARMASYSTEMS INC.

Inventor： Christopher A. PROCYSHYN ,  Marcin CICHY

IPC: G01N35/10 ,  A61J1/12 ,  A61J1/14 ,  A61J1/20 ,  A61L2/07 ,  A61L2/16 ,  A61L2/24 ,  B01L1/02 ,  B01L1/04 ,  B01L3/02 ,  B25J21/00 ,  B65B3/00 ,  B65B3/04 ,  B65B55/12 ,  C12M1/00 ,  C12M1/12 ,  G01N35/00

Abstract: A controlled environment enclosure comprises a robotic arm manipulation system used to protect and unprotect a fluid path and a swab within the controlled environment enclosure. The apparatus allows the fluid path to be protected against dangerous decontamination vapors and chemicals before the controlled environment enclosure is decontaminated. The apparatus allows the fluid path to be unprotected without the use of gloves or other means that degrade the integrity of the controlled environment enclosure when decontamination is completed, which may be automated. In some embodiments the fluid path comprises a fill needle that can removably and aseptically be sealed with a disposable monolithic injection moulded polymeric fill needle sheath. The apparatus and method further allow for the use of a swab disposed in a swab holder that is aseptically and removably sealable to a swab cap to protect the swab against decontamination vapors.

公开(公告)号：US20220391349A1

公开(公告)日：2022-12-08

申请号：US17681810

申请日：2022-02-27

Applicant: Vanrx Pharmasystems Inc.

Inventor： Christopher A. PROCYSHYN ,  Ross M. GOLD

IPC: G06F16/00 ,  B25J21/00 ,  B65B55/02 ,  B65B3/00 ,  B65B7/28 ,  H04M1/72409 ,  G06F1/16 ,  H04M1/04

Abstract: Systems and methods permit filling containers with a product. A filling arm is disposed within a chamber. An optical sensor is configured to sense openings of the containers within the chamber. Locations of the sensed openings are used to guide the filling arm to fill the containers with a product.

公开(公告)号：US20220196694A1

公开(公告)日：2022-06-23

申请号：US17691258

申请日：2022-03-10

Applicant: VANRX PHARMASYSTEMS INC.

Inventor： Christopher A. PROCYSHYN ,  Marcin CICHY

IPC: G01N35/10 ,  A61J1/14 ,  A61J1/20 ,  B65B55/12 ,  B65B3/04 ,  B65B3/00 ,  A61J1/12 ,  B01L1/04 ,  A61L2/07 ,  A61L2/16 ,  A61L2/24 ,  B01L1/02 ,  B25J21/00 ,  C12M1/00 ,  C12M1/12 ,  B01L3/02 ,  G01N35/00

Abstract: A controlled environment enclosure comprises a robotic arm manipulation system used to protect and unprotect a fluid path and a swab within the controlled environment enclosure. The apparatus allows the fluid path to be protected against dangerous decontamination vapors and chemicals before the controlled environment enclosure is decontaminated. The apparatus allows the fluid path to be unprotected without the use of gloves or other means that degrade the integrity of the controlled environment enclosure when decontamination is completed. The apparatus and method allow for the protecting, unprotecting and decontaminating sequences to be automated. In some embodiments the fluid path comprises a fill needle that can removably and aseptically be sealed with a disposable monolithic injection moulded polymeric fill needle sheath. The apparatus and method further allow for the use of a swab disposed in a swab holder that is aseptically and removably sealable to a swab cap to protect the swab against decontamination vapors.

公开(公告)号：US20220194646A1

公开(公告)日：2022-06-23

申请号：US17681814

申请日：2022-02-27

Applicant: VANRX PHARMASYSTEMS INC.

Inventor： Christopher A. PROCYSHYN ,  Ross M GOLD ,  Steve Sang Joon PARK ,  Jeroen IMMERZEEL ,  Paul NOWAKCZYK

IPC: B65B69/00 ,  B25J11/00

Abstract: An apparatus and method are presented for removing container covers within a controlled environment enclosure with pre-sterilized nested containers without using gloves. The apparatus comprises an articulated arm apparatus and a gripping apparatus for the pre-sterilized nested containers and can further comprise a controller. The articulated arm apparatus can be configurable for holding and moving a container in three dimensions; and the gripping apparatus can be configured for gripping a container cover sealing the container. The method comprises providing the pre-sterilized nested containers in the form of a container having a plurality of decontaminated parts, moving the container using the articulated arm apparatus while holding a gripping area of the container cover substantially stationary using the gripping apparatus. The apparatus can further comprise a sensor configured for supplying information to the controller for determining the location of the container cover gripping area and an orientation of the container cover. The method can further comprise inspecting the container cover using the sensor. The container can be moved along a path and within a space determined by the controller.

公开(公告)号：US20200156812A1

公开(公告)日：2020-05-21

申请号：US16431549

申请日：2019-06-04

Applicant: VANRX PHARMASYSTEMS INC.

Inventor： Christopher A. PROCYSHYN ,  Juvenal NAING ,  John SENGER ,  Marcin Czeslaw CICHY

IPC: B65B3/00 ,  B67C3/00 ,  B65B55/02 ,  A61M5/178

Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.