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公开(公告)号：US11656179B2
公开(公告)日：2023-05-23
申请号：US17380459
申请日：2021-07-20
Applicant: UNIVERSAL BIO RESEARCH CO., LTD.
Inventor： Hideji Tajima
IPC: G01N21/64 , G01N35/04 , G01N35/02 , G02B21/00 , G01N21/76 , G01N21/25 , C12Q1/686 , G01N21/11 , G01N35/10 , G01N21/27
CPC classification number: G01N21/6428 , C12Q1/686 , G01N21/253 , G01N21/6452 , G01N21/6454 , G01N21/76 , G01N35/02 , G01N35/04 , G02B21/002 , G01N21/11 , G01N21/276 , G01N21/6456 , G01N35/026 , G01N35/028 , G01N35/1002 , G01N35/1065 , G01N2021/6484 , G01N2035/0403 , G01N2201/0846 , G01N2201/0853
Abstract: An optical measurement device is provided. The device includes first and second optical fibers; first and second reaction vessels, and a light guide stage coupled to the first and second optical fibers. The light guide stage is driven to simultaneously optically connect the first and second optical fibers with the first and second reaction vessels. The device includes a measurement device for receiving emissions from the first and second reaction vessels, and a connecting end arranging body that supports the first and second optical fibers along a path. The arranging body is driven along the path between a first position, in which the first optical fiber is optically connected with the measurement device so that light is transmittable from the first reaction vessel, and a second position, in which the second optical fiber is optically connected with the measurement device so that light is transmittable from the second reaction vessel.
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公开(公告)号：US09976192B2
公开(公告)日：2018-05-22
申请号：US15284396
申请日：2016-10-03
Applicant: LDIP, LLC
Inventor： Reuven Duer , Yun-Pei Chang , Ashutosh Shastry
CPC classification number: C12Q1/703 , B01L3/502715 , B01L7/52 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , C12Q1/6825 , G01N21/6428 , G01N21/6452 , G01N33/54373 , G01N2021/6463 , G01N2201/0853 , G01N2201/10 , G02B6/4226
Abstract: The invention provides methods and devices for generating optical pulses in one or more waveguides using a spatially scanning light source. A detection system, methods of use thereof and kits for detecting a biologically active analyte molecule are also provided. The system includes a scanning light source, a substrate comprising a plurality of waveguides and a plurality of optical sensing sites in optical communication with one or more waveguide of the substrate, a detector that is coupled to and in optical communication with the substrate, and means for spatially translating a light beam emitted from said scanning light source such that the light beam is coupled to and in optical communication with the waveguides of the substrate at some point along its scanning path. The use of a scanning light source allows the coupling of light into the waveguides of the substrate in a simple and cost-effective manner.
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公开(公告)号：US09719917B2
公开(公告)日：2017-08-01
申请号：US13130166
申请日：2009-11-23
Applicant: Hakan Frojdh , Mikael Hornqvist , Stig Tormod , Patrik Akerstrom
Inventor： Hakan Frojdh , Mikael Hornqvist , Stig Tormod , Patrik Akerstrom
CPC classification number: G01N21/33 , G01J3/0218 , G01J3/0291 , G01J3/42 , G01J3/433 , G01N21/05 , G01N21/51 , G01N2021/0346 , G01N2201/061 , G01N2201/0853 , G01N2201/086
Abstract: The present invention discloses a flow cell optical detection system comprising a light source, a flow cell and a light detector, wherein the light detector is arranged in a separate detector unit that is arranged to be releasably attached to a detector interface, the detector interface being in optical communication with the light source and comprises optical connectors for optically connecting the flow cell and the detector unit in the light path from the light source, and wherein the flow cell is an interchangeable unit arranged to be held in position by the detector unit when attached to the detector interface.
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公开(公告)号：US09075002B2
公开(公告)日：2015-07-07
申请号：US10588891
申请日：2005-02-11
Applicant: Bryan E. Cole , Simon J. Chandler
Inventor： Bryan E. Cole , Simon J. Chandler
IPC: G01N21/49 , G01N21/3581 , G01N21/47 , G01N21/3563 , G01N21/17
CPC classification number: G01N21/3581 , G01N21/3563 , G01N21/474 , G01N21/49 , G01N2021/1772 , G01N2201/0853
Abstract: A probe array (1) for an imaging system for examining an object (19) comprising at least one emitter (7) for emitting radiation, a plurality of detectors (9) for detecting radiation and means for directing radiation emitted by the at least one emitter (7) to the object (19) and for directing radiation reflected from the object (19) to at least two of the plurality of detectors (9) wherein in use the emitted radiation is scanned by means (21) across the object (19).
Abstract translation: 一种用于检查物体（19）的成像系统的探针阵列（1），包括用于发射辐射的至少一个发射器（7），用于检测辐射的多个检测器（9）和用于引导由所述至少一个 发射器（7）到物体（19）并且用于将从物体（19）反射的辐射引导到多个检测器（9）中的至少两个，其中在使用中，所发射的辐射通过装置（21）扫过物体 19）。
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公开(公告)号：US20110013190A1
公开(公告)日：2011-01-20
申请号：US12800860
申请日：2010-05-24
Applicant: Mark Salerno , I-Tsung Shih , Craig Harrison
Inventor： Mark Salerno , I-Tsung Shih , Craig Harrison
IPC: G01N21/00
CPC classification number: G01N21/31 , G01N21/00 , G01N21/0303 , G01N21/05 , G01N21/255 , G01N21/59 , G01N2021/0346 , G01N2201/0612 , G01N2201/0853 , G01N2201/121
Abstract: This disclosure relates generally to a sampling device, and more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms and methods for such a device.
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Patent Agency Ranking
公开(公告)号：US07808641B2
公开(公告)日：2010-10-05
申请号：US12100467
申请日：2008-04-10
Applicant: Mark Salerno , Tsung Shih , Craig Harrison
Inventor： Mark Salerno , Tsung Shih , Craig Harrison
IPC: G01N21/00
CPC classification number: G01N21/31 , G01N21/00 , G01N21/0303 , G01N21/05 , G01N21/255 , G01N21/59 , G01N2021/0346 , G01N2201/0612 , G01N2201/0853 , G01N2201/121
Abstract: This disclosure relates generally to a sampling device, and, more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms, and methods for using such a device.
Abstract translation: 本公开一般涉及采样装置，更具体地，涉及利用可变路径长度和必要的软件控制算法以及使用这种装置的方法促进光谱测量的采样装置。
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公开(公告)号：US20070158571A1
公开(公告)日：2007-07-12
申请号：US10588891
申请日：2006-02-11
Applicant: Bryan Cole , Simon Chandler
Inventor： Bryan Cole , Simon Chandler
IPC: G01N22/00
CPC classification number: G01N21/3581 , G01N21/3563 , G01N21/474 , G01N21/49 , G01N2021/1772 , G01N2201/0853
Abstract: A probe array (1) for an imaging system for examining an object (19) comprising at least one emitter (7) for emitting radiation, a plurality of detectors (9) for detecting radiation and means for directing radiation emitted by the at least one emitter (7) to the object (19) and for directing radiation reflected from the object (19) to at least two of the plurality of detectors (9) wherein in use the emitted radiation is scanned by means (21) across the object (19)
Abstract translation: 一种用于检查物体（19）的成像系统的探针阵列（1），包括用于发射辐射的至少一个发射器（7），用于检测辐射的多个检测器（9）和用于引导由所述至少一个 发射器（7）到物体（19）并且用于将从物体（19）反射的辐射引导到多个检测器（9）中的至少两个，其中在使用中，所发射的辐射通过装置（21）扫过物体 19）
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18.发明授权公开(公告)号：US06396581B1
公开(公告)日：2002-05-28
申请号：US09492302
申请日：2000-01-27
Applicant: Toshinori Hayashi , Takahiko Ishiguro
Inventor： Toshinori Hayashi , Takahiko Ishiguro
IPC: G01N2164
CPC classification number: G01N21/645 , G01N21/253 , G01N35/025 , G01N2201/0231 , G01N2201/0423 , G01N2201/043 , G01N2201/0806 , G01N2201/0853
Abstract: A fluorescence detection apparatus is provided which comprises a sample holder for holding stationarily sample vessels deployed along a circle line or concentric circle lines having different radiuses, a partition plate connected to a driving means to be rotatable around the center of the circle line or concentric circle lines, an optical means for excitation light and an optical means for fluorescence light fixed respectively to the partition plate to be rotatable in integration therewith, a first light guide constituted of numerous optical fibers, a photosensor, and a light source for generating the excitation light, wherein the partition plate, the optical means for excitation light, and the optical means for fluorescence are integrally rotated, and thereby the fluorescence of the sample arranged along the circle line is successively detected and the detected fluorescence is transmitted to the photosensor. This fluorescence detection apparatus is useful in real-time monitoring of fluorescence signals, and satisfies the requirements of precise temperature control, quick treatment of many samples, high sensitivity, high reliability, low cost, and small size of the apparatus.
Abstract translation: 提供了一种荧光检测装置，其包括用于保持沿着圆线展开的固定样品容器的样本保持器或具有不同半径的同心圆线，连接到驱动装置的分隔板，以可围绕圆线或同心圆的中心旋转 线路，用于激发光的光学装置和用于荧光的光学装置分别固定在分隔板上以使其一体旋转;由多个光纤构成的第一导光体，光电传感器和用于产生激发光的光源 其中分隔板，用于激发光的光学装置和用于荧光的光学装置一体地旋转，从而连续检测沿着圆线排列的样品的荧光，并将检测到的荧光传输到光电传感器。 该荧光检测装置可用于实时监测荧光信号，满足精密温度控制，快速处理多种样品，高灵敏度，高可靠性，低成本，体积小的要求。
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公开(公告)号：US20240310282A1
公开(公告)日：2024-09-19
申请号：US18183309
申请日：2023-03-14
Applicant: SEEGENE, INC.
Inventor： Simon Philip Adam HIGGINS , Trevor David Shields , Stuart John Knowles , Walson Lawi
IPC: G01N21/64
CPC classification number: G01N21/6452 , G01N2201/021 , G01N2201/0853
Abstract: An apparatus for detecting optical signals according to the present disclosure includes a movable mount for carrying a set of light guides, the set of light guides having an excitation light guide and an emission light guide; an excitation light engine module for providing light to the excitation light guide; and an emission light detector module for detecting light from the emission light guide, wherein each distal end of the excitation light guide and the emission light guide are respectively connected to the excitation light engine module and the emission light detector module, wherein each proximal end of the excitation light guide and the emission light guide are both connected to the movable mount, and moved via the movable mount to be in optical communication with one reaction cavity at a time, among a plurality of reaction cavities.
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公开(公告)号：US09709506B2
公开(公告)日：2017-07-18
申请号：US14912577
申请日：2015-08-11
Inventor： Zhiqiang Wang , Bin Wu , Guangzhi Li , Xing Yue , Xuequan Yu , Jiajia Liu
CPC classification number: G01N21/88 , G01N21/55 , G01N21/95 , G01N2021/9513 , G01N2201/0853 , G01N2201/088 , H01L21/67288
Abstract: The present invention relates to the technical field of display, and particularly relates to a substrate damage inspection apparatus, a production system and an inspection method. The substrate damage inspection apparatus comprises a drive unit, support rods, sensors and a controller, wherein the drive unit is connected with the support rods so as to drive the support rods to ascend or descend below a substrate to be detected; and the sensors are disposed on the support rods and communicatively connect with the controller, so as to emit light beams to the substrate to be detected, receive the light beams reflected by the substrate to be detected, and feed them back to the controller. By means of the drive unit and the support rods with the sensors, the substrate damage inspection apparatus realizes damage inspection for the substrate to be detected in a vertical direction. That is, a technical solution provided by the present invention allows for damage inspection for the substrate to be detected when it vertically moves. In addition, the substrate damage inspection apparatus is simple in structure and convenient to operate, thereby having strong utility value and significance of generalization.
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