公开(公告)号：US08696992B2

公开(公告)日：2014-04-15

申请号：US13388885

申请日：2010-08-05

Applicant: Hideji Tajima

Inventor： Hideji Tajima

IPC: G01N21/00 ,  G01N21/76 ,  C12M1/34 ,  G01N21/25

CPC classification number: G01N21/6452 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/024 ,  G01J3/0291 ,  G01J3/08 ,  G01J3/10 ,  G01J3/32 ,  G01J3/4406 ,  G01J2003/1213 ,  G01N21/253 ,  G01N35/028 ,  G01N2021/6484 ,  G01N2201/0826 ,  G01N2201/0833 ,  G02B6/4298

Abstract: Disclosed is a highly reliable optical fiber measurement device and measurement method having a simple and compact structure. The device includes a planar liquid holder having a plurality of liquid holding portions arranged along a flat face; a plurality of light receiving optical fibers for transmitting fluorescence generated in the liquid holding portions; a plurality of light emitting optical fibers for transmitting excitation light into the liquid holding portions; a measurement head capable of being positioned in the each liquid holding portion while supporting a plurality of measurement ends having a bundle of one light receiving end of the light receiving optical fibers and one light emitting end of light emitting optical fibers; a light reception selecting element that, by sequentially selecting one by one from plural the light receiving optical fibers and sequentially selecting one by one from plural kinds of wavelength or wavelength bands, sequentially guides the light of the selected wavelength or wavelength band of the fluorescence received by the selected light receiving optical fibers to one photoelectric element; and a photoelectric element for sequentially conducting photoelectric conversion on the guided fluorescence.

Abstract translation: 公开了一种具有简单紧凑结构的高度可靠的光纤测量装置和测量方法。 该装置包括具有沿着平坦表面布置的多个液体保持部分的平面液体保持器; 多个用于透射在液体保持部分中产生的荧光的光接收光纤; 用于将激发光发射到液体保持部分中的多个发光光纤; 测量头，其能够定位在每个液体保持部分中，同时支撑具有光接收光纤的一个光接收端的束和发光光纤的一个发光端的多个测量端; 光接收选择元件，通过从多个光接收光纤中逐一选择并从多种波长或波长带中逐个选择一个顺序地选择所接收的荧光的所选波长或波长带的光， 通过所选择的光接收光纤到一个光电元件; 以及用于对引导荧光进行光电转换的光电元件。

公开(公告)号：US20140045250A1

公开(公告)日：2014-02-13

申请号：US13833349

申请日：2013-03-15

Applicant: STRECK, INC.

Inventor： Matthew R. Kreifels ,  Scott E. Whitney ,  Joel R. TerMaat

IPC: C12Q1/68

CPC classification number: C12Q1/686 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6484 ,  G01N2201/0627 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths.

Abstract translation: 一种用于促进聚合酶链反应的改进的装置和系统，包括占据最小空间的光源，检测器，波导和滤波器，并且有助于减少样品读取时间和快速读取多个光波长。

公开(公告)号：US20130155407A1

公开(公告)日：2013-06-20

申请号：US13714807

申请日：2012-12-14

Applicant: Commissariat a I'energie atomique et aux energies alternatives

Inventor： Lionel Herve

IPC: G01N21/59 ,  G01N21/64

CPC classification number: G01N21/59 ,  A61B5/0071 ,  A61B5/0073 ,  A61B5/4064 ,  A61B5/4255 ,  A61B5/4312 ,  A61B5/4381 ,  A61B5/7253 ,  G01N21/4795 ,  G01N21/49 ,  G01N21/64 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2021/1787 ,  G01N2021/6413 ,  G01N2021/6484 ,  G01N2201/0697 ,  G01N2201/0826 ,  G01N2201/0833 ,  G06T11/003 ,  G09B23/286

Abstract: A method reconstructing the optical properties of a medium using a reconstruction system has a radiation source lighting the medium and a detector receiving a signal transmitted by the medium. The steps include lighting the medium using a radiation source, receiving by the detector of a signal emitted by the medium, and processing, for a source-detector pair, of a first distribution of the signal received by the corresponding detector. Then computing the Mellin-Laplace transform, for a given order and a given variable, of a magnitude comprising the first distribution, the order being an integer, the variable being a real number, and reconstructing optical properties of the medium using the Mellin-Laplace transform of said magnitude. The computation step includes computing a plurality of Mellin-Laplace transforms of the magnitude for distinct values of the order, and the reconstruction step is carried out from a combination of the plurality of Mellin-Laplace transforms.

Abstract translation: 使用重建系统重建介质的光学特性的方法具有照射介质的辐射源和接收由介质传输的信号的检测器。 这些步骤包括使用辐射源照亮介质，由检测器接收由介质发射的信号，以及对源检测器对处理由相应的检测器接收的信号的第一分布。 然后，对于给定的顺序和给定的变量，计算包含第一分布的幅度的Mellin-Laplace变换，该顺序是整数，该变量是实数，并使用Mellin-Laplace重建介质的光学性质 转换所述幅度。 所述计算步骤包括计算所述次序的不同值的幅度的多个Mellin-Laplace变换，并且所述重建步骤是从所述多个Mellin-Laplace变换的组合中执行的。

公开(公告)号：US20120190034A1

公开(公告)日：2012-07-26

申请号：US13388885

申请日：2010-08-05

Applicant: Hideji Tajima

Inventor： Hideji Tajima

IPC: G01N21/76 ,  C12M1/34

CPC classification number: G01N21/6452 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/024 ,  G01J3/0291 ,  G01J3/08 ,  G01J3/10 ,  G01J3/32 ,  G01J3/4406 ,  G01J2003/1213 ,  G01N21/253 ,  G01N35/028 ,  G01N2021/6484 ,  G01N2201/0826 ,  G01N2201/0833 ,  G02B6/4298

Abstract: Disclosed is a highly reliable optical fiber measurement device and measurement method having a simple and compact structure. The device includes a planar liquid holder having a plurality of liquid holding portions arranged along a flat face; a plurality of light receiving optical fibers for transmitting fluorescence generated in the liquid holding portions; a plurality of light emitting optical fibers for transmitting excitation light into the liquid holding portions; a measurement head capable of being positioned in the each liquid holding portion while supporting a plurality of measurement ends having a bundle of one light receiving end of the light receiving optical fibers and one light emitting end of light emitting optical fibers; a light reception selecting element that, by sequentially selecting one by one from plural the light receiving optical fibers and sequentially selecting one by one from plural kinds of wavelength or wavelength bands, sequentially guides the light of the selected wavelength or wavelength band of the fluorescence received by the selected light receiving optical fibers to one photoelectric element; and a photoelectric element for sequentially conducting photoelectric conversion on the guided fluorescence.

Abstract translation: 公开了一种具有简单紧凑结构的高度可靠的光纤测量装置和测量方法。 该装置包括具有沿着平坦表面布置的多个液体保持部分的平面液体保持器; 多个用于透射在液体保持部分中产生的荧光的光接收光纤; 用于将激发光发射到液体保持部分中的多个发光光纤; 测量头，其能够定位在每个液体保持部分中，同时支撑具有光接收光纤的一个光接收端的束和发光光纤的一个发光端的多个测量端; 光接收选择元件，通过从多个光接收光纤中逐一选择并从多种波长或波长带中逐个选择一个顺序地选择所接收的荧光的所选波长或波长带的光， 通过所选择的光接收光纤到一个光电元件; 以及用于对引导荧光进行光电转换的光电元件。

公开(公告)号：US20110118572A1

公开(公告)日：2011-05-19

申请号：US12875983

申请日：2010-09-03

Applicant: Kate Leeann Bechtel ,  Tobias Funk ,  Brian Patrick Wilfley ,  Joseph Anthony Heanue

Inventor： Kate Leeann Bechtel ,  Tobias Funk ,  Brian Patrick Wilfley ,  Joseph Anthony Heanue

IPC: A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/0059 ,  A61B5/0091 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4312 ,  A61B5/6814 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2562/0233 ,  A61B2562/046 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/2823 ,  G01J3/4406 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: The present invention pertains to a method and apparatus for total hemoglobin measurement. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Total hemoglobin is determined based on the temporal transfer characteristic.

Abstract translation: 本发明涉及总血红蛋白测量的方法和装置。 基于数字码序列的调制光信号被传送到人体组织。 从调制光信号导出时间传递特性。 基于时间转移特性确定总血红蛋白。

公开(公告)号：US07876442B2

公开(公告)日：2011-01-25

申请号：US12005694

申请日：2007-12-27

Applicant: Kazutoshi Tokunaga ,  Norimasa Yamamoto

Inventor： Kazutoshi Tokunaga ,  Norimasa Yamamoto

IPC: G01N21/25

CPC classification number: G01N21/31 ,  G01N21/253 ,  G01N21/82 ,  G01N35/025 ,  G01N2021/3174 ,  G01N2021/825 ,  G01N2201/0826

Abstract: An analyzer is provided with a light irradiation device. The light irradiation device includes a light source, and a rotatable filter section, which has a plurality of optical filters having different light transmission characteristics, and irradiates an analyzing object with light that passed through the optical filters arranged in a path of the light from the light source while the filter section is rotating, by successively switching the optical filters by rotating the filter section. The analyzer is also provided with an analyzing means for analyzing characteristics of the analyzing object, based on optical information obtained from the analyzing object irradiated with the light by the light irradiation device while the filter section is rotating.

Abstract translation: 分析仪设有光照射装置。 光照射装置包括光源和可旋转滤光器部分，其具有多个具有不同透光特性的滤光器，并且利用通过布置在来自光源的光的路径中的滤光器的光照射分析对象 过滤器部分旋转时，通过旋转过滤器部分依次切换光学滤光器。 分析仪还具有分析装置，用于根据从过滤器部分旋转时由光照射装置照射光的分析对象获得的光学信息，分析分析对象的特性。

公开(公告)号：US20100262018A1

公开(公告)日：2010-10-14

申请号：US12740145

申请日：2008-10-28

Applicant: Levinus Pieter Bakker ,  Bernhard J. Brendel ,  Rik Harbers ,  Martinus Bernardus Van Der Mark

Inventor： Levinus Pieter Bakker ,  Bernhard J. Brendel ,  Rik Harbers ,  Martinus Bernardus Van Der Mark

IPC: A61B6/00

CPC classification number: G01N21/4795 ,  A61B5/0091 ,  A61B5/4312 ,  G01N21/15 ,  G01N2021/1787 ,  G01N2021/4719 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A method of controlling a device for imaging the interior of turbid media is provided. The device comprises: a receiving portion (2) for receiving a turbid medium (1) to be examined; at least one light source (6) optically connected to the receiving portion (2) for irradiating the interior of the receiving portion (2); and at least one detector (7) optically connected to the receiving portion (2) for detecting light emanating from the interior of the receiving portion (2). The at least one light source (6) and the at least one detector (7) areoptically connected to the receiving portion (2) such that a plurality of different source-detector position combinations are formed over a complete measurement. The different source-detector position combinations define different light paths through the receiving portion (2). The method comprises a fast-measurement step in which a reduced set of data corresponding to only a part of the plurality of source-detector position combinations is generated for providing fast-information about the interior of the receiving portion (2).

Abstract translation: 提供了一种控制用于对浑浊介质内部进行成像的装置的方法。 该装置包括：接收部分（2），用于接收待检查的混浊介质（1）; 至少一个光源（6），其光学连接到所述接收部分（2）以照射所述接收部分（2）的内部; 以及光学连接到所述接收部分（2）的至少一个检测器（7），用于检测从所述接收部分（2）的内部发出的光。 所述至少一个光源（6）和所述至少一个检测器（7）光学地连接到所述接收部分（2），使得在完整测量上形成多个不同的源 - 检测器位置组合。 不同的源 - 检测器位置组合限定穿过接收部分（2）的不同光路。 该方法包括快速测量步骤，其中生成仅对应于多个源 - 检测器位置组合的一部分的减少的数据集合，用于提供关于接收部分（2）的内部的快速信息。

公开(公告)号：US20100238441A1

公开(公告)日：2010-09-23

申请号：US12682939

申请日：2008-10-13

Applicant: Thomas Koehler ,  Tim Nielsen ,  Bernhard Brendel ,  Andy Ziegler ,  Ronny Ziegler ,  Levinus Pieter Bakker ,  Martinus Bernardus Van Der Mark

Inventor： Thomas Koehler ,  Tim Nielsen ,  Bernhard Brendel ,  Andy Ziegler ,  Ronny Ziegler ,  Levinus Pieter Bakker ,  Martinus Bernardus Van Der Mark

IPC: G01N21/49 ,  G01N21/00

CPC classification number: G01N21/4795 ,  A61B5/0073 ,  A61B5/0091 ,  A61B5/4312 ,  A61B2562/146 ,  G01N2021/1787 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A device (1) for imaging the interior of an optically turbid medium is provided. The device comprises a receptacle (3; 103) structured to accommodate an optically turbid medium for examination and an optically matching medium filling a space between an inner surface (6; 106) of the receptacle (3; 103) and the optically turbid medium. The device comprises at least one light source generating light to be coupled into the receptacle (3; 103) and at least one detector for detecting light emanating from the receptacle (3; 103). A coupling surface (10; 110) optically coupled to the inner surface (6; 106) of the receptacle and a coupling member (11; 111) optically coupled to the light source and the detector are provided. The coupling surface (10; 110) and the coupling member (11; 111) are movable to a plurality of different positions relative to each other and structured to establish an optical connection from the light source to the inner surface (6; 106) of the receptacle and from the inner surface (6; 106) of the receptacle to the at least one detector in the plurality of different positions.

Abstract translation: 提供了用于对光学混浊介质的内部成像的装置（1）。 该装置包括构造成容纳用于检查的光学混浊介质的容器（3; 103）和填充容器（3; 103）的内表面（6; 106）与光学混浊介质之间的空间的光学匹配介质。 所述装置包括至少一个光源，其产生要耦合到所述插座（3; 103）中的光和至少一个用于检测从所述插座（3; 103）发出的光的检测器。 光耦合到容器的内表面（6; 106）的耦合表面（10; 110）和光学耦合到光源和检测器的耦合构件（11; 111）。 联接表面（10; 110）和联接构件（11; 111）可以相对于彼此移动到多个不同的位置，并被构造成建立从光源到内表面（6; 106）的光学连接 所述容器和所述容器的内表面（6; 106）到所述多个不同位置中的所述至少一个检测器。

公开(公告)号：US07800495B1

公开(公告)日：2010-09-21

申请号：US12399966

申请日：2009-03-08

Applicant: Warren G. Parrish

Inventor： Warren G. Parrish

IPC: G08B21/00

CPC classification number: G01N21/7703 ,  G01N2021/7709 ,  G01N2021/7786 ,  G01N2021/7796 ,  G01N2201/0826

Abstract: An optical receiving and data communications system for sensing materials of interest (e.g., drugs and/or explosives) in transportation systems such as buses, trucks, cars, trains, aircraft, and ships, and checkpoints such as building entrances, roadblocks, passenger boarding areas, and the like. The system can be included in the transportation system, and includes a fiber optic front end that focuses and/or concentrates light reflected from a target into the fiber filament for communication to an optical sensor. When the target is illuminated at a predetermined wavelength, a vapor plume and/or particulate matter associated therewith is energized such that change information is caused to occur and be received into the fiber system. The change information is communicated over a fiber communications network to a remote processing and analysis system for processing and analysis to determine its chemical components.

Abstract translation: 用于传输公共汽车，卡车，汽车，火车，飞机和船舶等运输系统中感兴趣的材料（例如药物和/或爆炸物）的光学接收和数据通信系统，以及诸如建筑物入口，路障，乘客登机 区域等。 该系统可以包括在运输系统中，并且包括光纤前端，其将从目标反射的光聚焦和/或聚焦到纤维丝中以与光学传感器通信。 当靶以预定波长照明时，与其相关联的蒸汽羽流和/或颗粒物被激励，使得发生改变信息并被接收到光纤系统中。 变更信息通过光纤通信网络传送到远程处理和分析系统进行处理和分析，以确定其化学成分。

公开(公告)号：US07764172B1

公开(公告)日：2010-07-27

申请号：US12399965

申请日：2009-03-08

Applicant: Warren G. Parrish

Inventor： Warren G. Parrish

IPC: G08B21/00

CPC classification number: G01N21/7703 ,  G01N2021/7709 ,  G01N2021/7786 ,  G01N2021/7796 ,  G01N2201/0826

Abstract: An optical receiving and data communications system for sensing materials of interest (e.g., drugs and/or explosives) in transportation systems such as buses, trucks, cars, trains, aircraft, and ships, and checkpoints such as building entrances, roadblocks, passenger boarding areas, and the like. The system can be included in the transportation system, and includes a fiber optic frontend that focuses and/or concentrates light reflected from a target into the fiber filament for communication to an optical sensor. When the target is illuminated at a predetermined wavelength, a vapor plume and/or particulate matter associated therewith is energized such that change information is caused to occur and be received into the fiber system. The change information is communicated over a fiber communications network to a remote processing and analysis system for processing and analysis to determine its chemical components.

Abstract translation: 用于传输公共汽车，卡车，汽车，火车，飞机和船舶等运输系统中感兴趣的材料（例如药物和/或爆炸物）的光学接收和数据通信系统，以及诸如建筑物入口，路障，乘客登机 区域等。 该系统可以包括在运输系统中，并且包括光纤前端，其将从目标反射的光聚焦和/或聚焦到纤维丝中以与光学传感器通信。 当靶以预定波长照明时，与其相关联的蒸汽羽流和/或颗粒物被激励，使得发生改变信息并被接收到光纤系统中。 变更信息通过光纤通信网络传送到远程处理和分析系统进行处理和分析，以确定其化学成分。