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    Analyte detection meter and associated method of use
    21.
    发明授权
    Analyte detection meter and associated method of use 有权

    公开(公告)号：US11719687B2

    公开(公告)日：2023-08-08

    申请号：US16222683

    申请日：2018-12-17

    Applicant: AgaMatrix, Inc.

    Inventor： Sridhar Iyengar ,  Ian Harding ,  Richard Williams ,  Kevin Cai

    IPC: G01N33/487 ,  G01N27/327

    CPC classification number: G01N33/48771 ,  G01N27/3274

    Abstract: A method for obtaining information encoded on an electrochemical test strip is provided. The test strip has two electrodes disposed within a sample space and the information is encoded on the test strip prior to introduction of liquid sample. The method includes the step of introducing sample to the sample space so that the sample is in contact with the two electrodes within the sample space. In another step a value is determined that is representative of the double layer capacitance of the test strip and/or the equivalent capacitance of the test strip. The determined value is then translated into information reflecting a characteristic of the test strip prior to introduction of sample.

    Analyte test strip and analyte meter device
    22.
    发明授权
    Analyte test strip and analyte meter device 有权

    公开(公告)号：US10288577B2

    公开(公告)日：2019-05-14

    申请号：US15477485

    申请日：2017-04-03

    Applicant: AgaMatrix, Inc.

    Inventor： Sridhar Iyengar ,  Ian Harding ,  Charles Boiteau ,  Colin Butters

    IPC: G01N27/327 ,  G01N21/77 ,  G01N21/84 ,  G01N33/487 ,  G01N21/25 ,  G01J1/42

    Abstract: A test strip with an incorporated optical waveguide and deflectors punched through the optical waveguide allows light to exit through a layer of the test strip and be detected by a photo detector. Using light and a photodetector, these uniquely coded strips are identified. The waveguide can be constructed by sandwiching two layers of the test strip around a light transmissible layer. This configuration allows light to be transmitted through the test strip and out the other end, as well as allowing some light to escape the deflector. This light is detected by a photodetector mounted in the analyte test meter. The deflectors may be placed in patterns such that detection of this light indicates certain characteristics of the strip, such as non-counterfeit, regional identification, type of analyte tested, and coding information.

    Electrochemical Analyte Detection Apparatus and Method
    28.
    发明申请
    Electrochemical Analyte Detection Apparatus and Method 有权
    电化学分析物检测装置及方法

    公开(公告)号：US20160231321A1

    公开(公告)日：2016-08-11

    申请号：US15017787

    申请日：2016-02-08

    Applicant: AgaMatrix, Inc.

    Inventor： Ian Harding ,  Sridhar Iyengar ,  Richard Williams

    IPC: G01N33/573 ,  G01N27/416

    CPC classification number: G01N33/573 ,  C12Q1/001 ,  G01N27/4166 ,  G01N33/5438 ,  G01N2333/90 ,  G01N2333/902

    Abstract: A method and apparatus for electrochemical detection of analyte in a sample makes use of a binding interaction and relies on the discovery that asymmetric distribution of a redox enzyme between two electrodes that occurs when a redox enzyme-containing reagent is immobilized at the surface of one electrode can be detected as a chemical potential gradient arising from an asymmetry in the distribution of oxidized or reduced redox substrate. This chemical potential gradient can be detected potentiometrically by observing the potential difference between the electrodes in an open circuit, or amperometrically by observing the current flow between the electrodes when the circuit is closed. In both cases, the observation of asymmetry can be done without the application of an external potential or current to the electrodes.

    Abstract translation: 用于样品中分析物的电化学检测的方法和装置利用结合相互作用，并且依赖于以下发现：当在含有氧化还原酶的试剂固定在一个电极的表面时发生的氧化还原酶在两个电极之间的不对称分布 可以被检测为由氧化还原氧化还原底物的分布不对称引起的化学势梯度。 可以通过在断路中观察电极之间的电势差，或者当电路闭合时通过观察电极之间的电流来进行电流分析来电位检测该化学势梯度。 在这两种情况下，可以在不对电极施加外部电位或电流的情况下进行不对称性的观察。

    Implantable Electrochemical Biosensor System and Method
    30.
    发明申请
    Implantable Electrochemical Biosensor System and Method 有权
    植入式电化学生物传感器系统及方法

    公开(公告)号：US20150133758A1

    公开(公告)日：2015-05-14

    申请号：US14601851

    申请日：2015-01-21

    Applicant: AgaMatrix, Inc.

    Inventor： Sridhar Iyengar ,  Ian Harding

    IPC: A61B5/1486 ,  A61B5/145

    CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7225 ,  C12Q1/001 ,  C12Q1/006

    Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.

    Abstract translation: 校正聚合物层厚度的初始变化以及植入生物传感器之后发生的涂层厚度的变化，因此可以使用从电位衰减导出的因子提供可植入传感器的精度和使用寿命。

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