公开(公告)号：US11346803B2

公开(公告)日：2022-05-31

申请号：US15830897

申请日：2017-12-04

Applicant: AgaMatrix, Inc.

Inventor： Steven Diamond ,  Martin Forest ,  Baoguo Wei ,  Ian Harding ,  Sridhar Iyengar

IPC: G01N27/327 ,  B01L3/00

Abstract: A test strip and analytical apparatus have pin connections permitting the definition of geographic regions or of particular customers. A test strip made for use in a particular region or for a particular customer will have pin connections matching features of the apparatus made for use in that region or by that customer. Insertion of the strip into the apparatus does not merely turn on the apparatus, but provides the regional or customer coding. Analog switches within the apparatus allow coding of a larger number of distinct regions or customers than would otherwise be possible, all without degrading the quality of the measurements made of the fluid being tested. Conductive paths in the strips permit testing the strips during manufacture so as to detect quality lapses regarding the printing or deposition of the paths.

公开(公告)号：US20180080895A1

公开(公告)日：2018-03-22

申请号：US15825598

申请日：2017-11-29

Applicant: AgaMatrix, Inc.

Inventor： Ian Harding ,  Richard Williams ,  Sridhar Iyengar

IPC: G01N27/327 ,  C12Q1/00 ,  G01N27/30

CPC classification number: G01N27/3274 ,  C12Q1/006 ,  G01N27/307 ,  G01N27/327 ,  G01N27/3272 ,  G01N27/3273

Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.

公开(公告)号：US20170205370A1

公开(公告)日：2017-07-20

申请号：US15477485

申请日：2017-04-03

Applicant: AgaMatrix, Inc.

Inventor： Sridhar Iyengar ,  Ian Harding ,  Charles Boiteau ,  Colin Butters

IPC: G01N27/327 ,  G01N21/77 ,  G01N21/84 ,  G01N33/487

CPC classification number: G01N27/3272 ,  G01J1/42 ,  G01N21/255 ,  G01N21/7703 ,  G01N21/8483 ,  G01N27/327 ,  G01N27/3273 ,  G01N33/48707 ,  G01N33/48771 ,  G01N2201/08

Abstract: A test strip with an incorporated optical waveguide and deflectors punched through the optical waveguide allows light to exit through a layer of the test strip and be detected by a photo detector. Using light and a photodetector, these uniquely coded strips are identified. The waveguide can be constructed by sandwiching two layers of the test strip around a light transmissible layer. This configuration allows light to be transmitted through the test strip and out the other end, as well as allowing some light to escape the deflector. This light is detected by a photodetector mounted in the analyte test meter. The deflectors may be placed in patterns such that detection of this light indicates certain characteristics of the strip, such as non-counterfeit, regional identification, type of analyte tested, and coding information.

公开(公告)号：US09375173B2

公开(公告)日：2016-06-28

申请号：US14601851

申请日：2015-01-21

Applicant: AgaMatrix, Inc.

Inventor： Sridhar Iyengar ,  Ian Harding

IPC: A61B5/00 ,  A61B5/1486 ,  C12Q1/00 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7225 ,  C12Q1/001 ,  C12Q1/006

Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.

Abstract translation: 校正聚合物层厚度的初始变化以及植入生物传感器之后发生的涂层厚度的变化，因此可以使用从电位衰减导出的因子提供可植入传感器的精度和使用寿命。

公开(公告)号：US20180088071A1

公开(公告)日：2018-03-29

申请号：US15830897

申请日：2017-12-04

Applicant: AgaMatrix, Inc.

Inventor： Steven Diamond ,  Martin Forest ,  Baoguo Wei ,  Ian Harding ,  Sridhar Iyengar

IPC: G01N27/327 ,  B01L3/00

CPC classification number: G01N27/3272 ,  B01L3/5023 ,  B01L3/545 ,  B01L2300/02

Abstract: A test strip and analytical apparatus have pin connections permitting the definition of geographic regions or of particular customers. A test strip made for use in a particular region or for a particular customer will have pin connections matching features of the apparatus made for use in that region or by that customer. Insertion of the strip into the apparatus does not merely turn on the apparatus, but provides the regional or customer coding. Analog switches within the apparatus allow coding of a larger number of distinct regions or customers than would otherwise be possible, all without degrading the quality of the measurements made of the fluid being tested. Conductive paths in the strips permit testing the strips during manufacture so as to detect quality lapses regarding the printing or deposition of the paths.

公开(公告)号：US20160192871A1

公开(公告)日：2016-07-07

申请号：US15069071

申请日：2016-03-14

Applicant: AgaMatrix, Inc.

Inventor： Sridhar Iyengar ,  Ian Harding

IPC: A61B5/1486 ,  A61B5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7225 ,  C12Q1/001 ,  C12Q1/006

Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.

公开(公告)号：US09234862B2

公开(公告)日：2016-01-12

申请号：US14278299

申请日：2014-05-15

Applicant: AgaMatrix, Inc.

Inventor： Ian Harding ,  Richard Williams ,  Sridhar Iyengar

IPC: G01N27/327 ,  G01N27/30 ,  C12Q1/00

CPC classification number: G01N27/3274 ,  C12Q1/006 ,  G01N27/307 ,  G01N27/327 ,  G01N27/3272 ,  G01N27/3273

Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.

公开(公告)号：US20130118921A1

公开(公告)日：2013-05-16

申请号：US13723713

申请日：2012-12-21

Applicant: AGAMATRIX, INC.

Inventor： Ian Harding ,  Richard Williams ,  Sridhar Iyengar

IPC: G01N27/327

CPC classification number: G01N27/3274 ,  C12Q1/006 ,  G01N27/307 ,  G01N27/327 ,  G01N27/3272 ,  G01N27/3273

Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.

Abstract translation: 在施加到使用还原介体的电化学测试条的样品中的氧或红细胞的存在通过作为样品的温度的函数确定的添加剂校正因子来校正，并且反映 样品的氧气承载能力。 测量的氧气承载能力也可用于确定血细胞比容并区分血液样本和应用于测试条的对照溶液。

公开(公告)号：US20200333282A1

公开(公告)日：2020-10-22

申请号：US16840990

申请日：2020-04-06

Applicant: AgaMatrix, Inc.

Inventor： Ian Harding ,  Richard Williams ,  Sridhar Iyengar

IPC: G01N27/327 ,  C12Q1/00 ,  G01N27/30

Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.

公开(公告)号：US20190113498A1

公开(公告)日：2019-04-18

申请号：US16222683

申请日：2018-12-17

Applicant: AgaMatrix, Inc.

Inventor： Sridhar Iyengar ,  Ian Harding ,  Richard Williams ,  Kevin Cai

IPC: G01N33/487

Abstract: A method for obtaining information encoded on an electrochemical test strip is provided. The test strip has two electrodes disposed within a sample space and the information is encoded on the test strip prior to introduction of liquid sample. The method includes the step of introducing sample to the sample space so that the sample is in contact with the two electrodes within the sample space. In another step a value is determined that is representative of the double layer capacitance of the test strip and/or the equivalent capacitance of the test strip. The determined value is then translated into information reflecting a characteristic of the test strip prior to introduction of sample.