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    Thermo-electrically cooled surface enhanced Raman spectroscopy sensor system
    21.
    发明授权
    Thermo-electrically cooled surface enhanced Raman spectroscopy sensor system 有权
    热电冷表面增强拉曼光谱传感器系统

    公开(公告)号：US07116416B1

    公开(公告)日：2006-10-03

    申请号：US11136765

    申请日：2005-05-24

    Applicant: Pamela A. Boss ,  Stephen H. Lieberman ,  Leonard J. Martini ,  Gregory W. Anderson

    Inventor： Pamela A. Boss ,  Stephen H. Lieberman ,  Leonard J. Martini ,  Gregory W. Anderson

    IPC: G01J3/44

    CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y30/00 ,  G01N2201/0231

    Abstract: A sensor system employs a thermo-electrically cooled surface enhanced Raman (SERS) structure that is positioned in a sample chamber. Gas or vapor that may contain an analyte of interest is introduced into the sample chamber so that the analyte may come into contact with the SERS structure. The SERS structure may be cooled to facilitate condensation of selected analytes onto the SERS structure. When in contact with each other, the analyte and SERS structure may be optically stimulated by an optical excitation signal to produce a unique spectral response that may be detected by a spectroanalysis system. The spectral response then may be correlated to a specific analyte, i.e., identified.

    Abstract translation: 传感器系统采用位于样品室中的热电冷却表面增强拉曼（SERS）结构。 将可能含有感兴趣分析物的气体或蒸汽引入样品室，使得分析物可能与SERS结构接触。 可以冷却SERS结构以便于选择的分析物冷凝到SERS结构上。 当彼此接触时，分析物和SERS结构可以被光学激发信号光学刺激，以产生可由光谱分析系统检测的独特光谱响应。 然后光谱响应可以与特定分析物相关，即识别。

    Optical pH and gas concentration sensor
    23.
    发明授权
    Optical pH and gas concentration sensor 失效
    光学pH和气体浓度传感器

    公开(公告)号：US5039492A

    公开(公告)日：1991-08-13

    申请号：US303584

    申请日：1989-01-27

    Applicant: Elric W. Saaski ,  David A. McCrae ,  James C. Hartl ,  Dale M. Lawrence ,  Roger A. Wolthuis

    Inventor： Elric W. Saaski ,  David A. McCrae ,  James C. Hartl ,  Dale M. Lawrence ,  Roger A. Wolthuis

    IPC: G01N21/03 ,  G01N21/31 ,  G01N21/77 ,  G01N21/78 ,  G01N21/80

    CPC classification number: G01N21/77 ,  G01N21/783 ,  G01N2021/0314 ,  G01N2021/0385 ,  G01N2021/3144 ,  G01N21/80 ,  G01N2201/0231 ,  G01N2201/062 ,  G01N2201/0621 ,  Y10T436/207497 ,  Y10T436/209163 ,  Y10T436/22

    Abstract: An optical pH sensor and a gas sensor utilizing the pH sensor. The pH sensor includes an indicator whose absorbance is a function of the concentration of hydronium ions in a media surrounding the indicator. Light transmitted and reflected through the indicator of the sensor undergoes an absorption that is characteristic of the concentration of the hydrogen ion. The pH sensor can be used as to sense the concenration of a gas in a sample by surrounding the indicator with a liquid or liquid-containing media that changes pH as it is exposed to the gas, and separating the indicator and liquid or liquid-containing media from the gas with a membrane that is permeable to the gas to be measured. A measuring system used with the sensors transmits coherent radiation to the sensor through an optical fiber, separates the radiation returning from the sample into two wavelength bands, and digitally samples the photocurrents produced within the two wavelength bands. A microprocessor performs ratiometric calculations to measure the pH or gas concentration.

    Abstract translation: 光学pH传感器和利用pH传感器的气体传感器。 pH传感器包括指示剂，其吸光度是指示剂周围的介质中水合氢离子的浓度的函数。 通过传感器的指示器透射和反射的光经受吸收，其是氢离子浓度的特征。 pH传感器可以用于通过用液体或液体介质围绕指示剂来感测样品中气体的浓缩，所述液体或液体介质在暴露于气体时改变pH，并分离指示剂和液体或液体 来自具有可测量气体的膜的气体的介质。 与传感器一起使用的测量系统通过光纤将相干辐射传输到传感器，将从样品返回的辐射分离成两个波长带，并对在两个波长带内产生的光电流进行数字采样。 微处理器执行比例计算来测量pH或气体浓度。

    Method and apparatus for reducing Schlieren noise in a liquid chromatograph
    24.
    发明授权
    Method and apparatus for reducing Schlieren noise in a liquid chromatograph 失效
    用于降低液相色谱仪中Schlieren噪声的方法和装置

    公开(公告)号：US4659934A

    公开(公告)日：1987-04-21

    申请号：US617700

    申请日：1984-06-06

    Applicant: Robert W. Allington

    Inventor： Robert W. Allington

    IPC: G01N21/15 ,  G01N21/25 ,  G01N30/30 ,  G01N30/74 ,  G01N23/00

    CPC classification number: G01N21/251 ,  G01N21/15 ,  G01N30/74 ,  G01N2030/3038 ,  G01N2201/0231

    Abstract: A beam of light falling within the range of 180 to 3,000 nanometers is transmitted through a flow cell in an optical compartment of an absorbance detector after warm up of the equipment while the eluant flows through the flow cell from a chromatographic column. The column extends upwardly from the absorbance detector into an air chamber having a volume of approximately 0.25 cubic foot formed with acrylic walls. Air flows from the absorbance detector under the power of a fan at approximately 10 cubic feet per minute upwardly through an air duct having a cross section of approximately 1.5 square inches to the top where it connects with the air chamber, the speed of the motor being adjustable until temperature varies less than one degree Celsius between the flow cell and the lower 10 centimeters of the column. Under these conditions Schlieren noise from the flow cell due to flow-induced thermo-optical effects is reduced.

    Abstract translation: 落入180-3000纳米范围内的光束在设备预热后通过吸光度检测器的光学隔室中的流动池传输，同时洗脱液从色谱柱流过流动池。 该柱从吸光度检测器向上延伸到由丙烯酸壁形成的体积为约0.25立方英尺的空气室中。 空气从风扇的功率以约10立方英尺/分钟的速度向上流过吸收检测器，通过横截面大约为1.5平方英寸的空气管道与顶部连通，其与电动机的速度为 可调节，直到流动池和塔的下10厘米之间的温度变化不到1摄氏度。 在这些条件下，由流动引起的热光效应引起的流动池中的Schlieren噪声降低。

    LIGHT DETECTION DEVICE
    25.
    发明公开
    LIGHT DETECTION DEVICE 审中-公开

    公开(公告)号：US20240201081A1

    公开(公告)日：2024-06-20

    申请号：US18554570

    申请日：2022-01-28

    Applicant: SONY GROUP CORPORATION

    Inventor： YUSUKE MADA ,  ATSUSHI ITO ,  MASAKI ORIHASHI

    IPC: G01N21/3563 ,  F25B21/02

    CPC classification number: G01N21/3563 ,  F25B21/02 ,  G01N2201/0231

    Abstract: The present technology relates to a light detection device capable of receiving light from an object to be measured without interference. The light detection device includes a Peltier element configured of a P-type semiconductor and an N-type semiconductor disposed between a first substrate and a second substrate, and a light receiving part configured to receive light from the object having been subjected to temperature modulation by the Peltier element, in which the first substrate is provided on the object side, the second substrate is provided on the light receiving part side, and at least parts of the first substrate and the second substrate are configured to transmit light from the object. The present technology can be applied to, for example, a detection device that detects a predetermined material by receiving and analyzing light from an object to be measured.

    Raman spectroscopy based measurement system
    26.
    发明授权
    Raman spectroscopy based measurement system 有权

    公开(公告)号：US11906434B2

    公开(公告)日：2024-02-20

    申请号：US17714035

    申请日：2022-04-05

    Applicant: NOVA LTD

    Inventor： Yonatan Oren

    IPC: G01N21/65 ,  G01N21/95 ,  G03F7/00

    CPC classification number: G01N21/65 ,  G01N21/9501 ,  G03F7/70616 ,  G01N2201/0231 ,  G01N2201/06113

    Abstract: A method and system are presented for use in measuring one or more characteristics of patterned structures. The method comprises: performing measurements on a patterned structure by illuminating the structure with exciting light to cause Raman scattering of one or more excited regions of the pattern structure, while applying a controlled change of at least temperature condition of the patterned structure, and detecting the Raman scattering, and generating corresponding measured data indicative of a temperature dependence of the detected Raman scattering; and analyzing the measured data and generating data indicative of spatial profile of one or more properties of the patterned structure.

    Laser-Scatter Measurement Instrument Having Carousel-Based Fluid Sample Arrangement
    29.
    发明申请
    Laser-Scatter Measurement Instrument Having Carousel-Based Fluid Sample Arrangement 审中-公开

    公开(公告)号：US20180313753A1

    公开(公告)日：2018-11-01

    申请号：US16013643

    申请日：2018-06-20

    Applicant: BacterioScan LTD

    Inventor： Dana A. Marshall ,  Dan Vadim Regelman

    IPC: G01N21/51 ,  G01N21/03

    CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N2021/513 ,  G01N2201/0231 ,  G01N2201/0415

    Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.

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