公开(公告)号：US20240065983A1

公开(公告)日：2024-02-29

申请号：US18384528

申请日：2023-10-27

Applicant: University of South Florida

Inventor： Subhra Mohapatra ,  Shyam S. Mohapatra ,  Karthick Mayilsamy ,  Eleni Markoutsa ,  Andrew McGill

IPC: A61K9/51 ,  A61K31/4439 ,  A61K31/7105 ,  A61P31/14

CPC classification number: A61K9/5123 ,  A61K31/4439 ,  A61K31/7105 ,  A61P31/14

Abstract: A multi-functional broad-spectrum antiviral and anti-inflammatory nanosystem and methods of treating, including prophylactically, coronavirus infections, such as those caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by administering such nanosystem to a patient is presented. The nanosystem may be comprised of a combination of therapeutic agents directed to the particular coronavirus encapsulated in a nanoparticle that is surface coated with a targeting moiety. For CoV-2 infections, an antiviral such as the PPAR-γ agonist leriglitazone (LG) and an siRNA targeting a conserved sequence of the virus can be encapsulated within a nanoparticle surface coated with a fatty acid such as linoleic acid, as the targeting moiety. Administration can occur intranasally prior to infection for prophylactic treatment or post-infection for treatment of the viral infection.

公开(公告)号：US20240058223A1

公开(公告)日：2024-02-22

申请号：US18498333

申请日：2023-10-31

Applicant: University of South Florida ,  The United States Government as represented by the Department of Veterans Affairs

Inventor： William Diehl Kearns ,  Kimberly Ann Crosland ,  Jeffrey D. Craighead ,  James Leonard Fozard

IPC: A61J7/04 ,  A61J7/00 ,  G06K19/06

CPC classification number: A61J7/0481 ,  A61J7/0092 ,  G06K19/06028 ,  A61J7/0069 ,  A61J7/0076 ,  A61J7/0418 ,  A61J7/0445 ,  A61J2200/30 ,  G16H20/13

Abstract: A medication adherence system and corresponding medication box for improving medication adherence. The system includes the medication box, which is transparent and has a machine-readable marker, such as a QR code, on or beneath the floor thereof. The marker is capable of being scanned and read through the transparent bottoms of individual chambers. Data embedded in the marker includes, but is not limited to, the user's medication plan, the date and time when the medication is to be ingested, and instructions for recording the date and time when the marker is scanned and read. The underlying software program/application processes this information and provides an indication as to the user's compliance with the medication plan.

公开(公告)号：US20240043695A1

公开(公告)日：2024-02-08

申请号：US18458504

申请日：2023-08-30

Applicant: University of South Florida

Inventor： Manoj Kumar RAM

IPC: C09C3/06 ,  C09D7/65 ,  C09D7/40 ,  C09D7/62 ,  C09C1/00 ,  C09C1/44 ,  C09D5/24 ,  C09J9/02 ,  C09J11/04 ,  C09J11/08 ,  H01B1/02 ,  H01B1/12

CPC classification number: C09C3/066 ,  C09D7/65 ,  C09D7/70 ,  C09D7/62 ,  C09C1/0003 ,  C09C1/44 ,  C09D5/24 ,  C09J9/02 ,  C09J11/04 ,  C09J11/08 ,  H01B1/02 ,  H01B1/127 ,  C01P2004/61 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2004/80 ,  C01P2006/32 ,  C01P2006/40

Abstract: Hybrid particles having improved electrical conductivity and thermal and chemical stabilities are disclosed. The hybrid particles are for use in conductive pastes. The hybrid particles include a nanoparticle selected from a graphene-containing material, a dichalcogenide material, a conducting polymer, or a combination thereof encapsulated in a conducting metal. The hybrid particles include a nanoparticle selected from a graphene-containing material, a dichalcogenide material, or a combination thereof encapsulated in a conducting polymer, and optionally further in a conducting metal. Suitable conducting metals include nickel or silver. Suitable conducting polymers include polyaniline, polypyrrole, or polythiophene. Suitable dichalcogenide materials include MoS2 or MoSe2. The hybrid particles can further include a conducting polymer layer on an outer surface of the conducting metal. Methods of making the hybrid particles are also disclosed.

公开(公告)号：US11892294B1

公开(公告)日：2024-02-06

申请号：US17083674

申请日：2020-10-29

Applicant: University of South Florida

Inventor： Timothy Hugh Dixon

IPC: G01C13/00 ,  G01S19/42 ,  B63B22/00

CPC classification number: G01C13/006 ,  B63B22/00 ,  G01C13/004 ,  G01S19/42 ,  B63B2022/006

Abstract: Various examples are provided for systems and methods for geodesy in shallow water. In one example, a method includes obtaining, from a sensor module, a position of a superstructure of a moored device. At least one measurement corresponding to a heading, a pitch, or a roll of the superstructure can be obtained from the sensor module. An estimated position of an anchor, ballast, or other seafloor marker of the moored device can be determined based on the position of the superstructure and at least one corrected heading associated with the at least one measurement. The at least one corrected heading can be determined by applying a magnetic declination correction to the at least one measurement.

公开(公告)号：US11887316B2

公开(公告)日：2024-01-30

申请号：US17373276

申请日：2021-07-12

Applicant: University of South Florida

Inventor： Yu Sun ,  David Andres Paulius ,  Maxat Alibayev

IPC: G06T7/246 ,  G06V20/40

CPC classification number: G06T7/248 ,  G06V20/41 ,  G06V20/46 ,  G06T2207/10016 ,  G06T2207/30241

Abstract: A method for motion recognition and embedding is disclosed. The method may include receiving a plurality of frames of an input video for extracting a feature vector of a motion in the plurality of frames, generating a plurality of sets of one or more motion component bits based on the feature vector and a plurality of classifiers, the plurality of sets corresponding to the plurality of classifiers, each set of one or more motion component bits representing a physical or mechanical attribute of the motion; and generating a motion code for a machine to execute the motion by combining the plurality of sets of one or more motion component bits. Other aspects, embodiments, and features are also claimed and described.

公开(公告)号：US20240027356A1

公开(公告)日：2024-01-25

申请号：US18480863

申请日：2023-10-04

Applicant: University of South Florida

Inventor： Robert H. Byrne

IPC: G01N21/80 ,  G01N33/18

CPC classification number: G01N21/80 ,  G01N33/18

Abstract: Disclosed herein are methods for measuring the ionic strengths of the natural water sources. Also disclosed herein are systems used to measure an ionic strength of the natural water sources. More specifically disclosed herein are methods and systems utilizing spectroscopic pH measurements and calculations of the ionic strength as a function of the measured pH.

公开(公告)号：US20240026611A1

公开(公告)日：2024-01-25

申请号：US18479539

申请日：2023-10-02

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Qing Lu ,  Lukai Guo

IPC: E01C1/00 ,  H02N2/18

CPC classification number: E01C1/002 ,  H02N2/183

Abstract: An energy harvesting roadway that includes a plurality of road segments and a power storage device electrically coupled to the plurality of road segments. Each of the plurality of road segments can include a surface asphalt layer, a first conductive asphalt layer located under the surface asphalt layer, a piezoelectric-based asphalt layer located between the first conductive layer and a second conductive layer located above a base asphalt layer. The piezoelectric-based asphalt layer can include a plurality of rigid piezoelectric elements and an insulating filler.

公开(公告)号：US20240018051A1

公开(公告)日：2024-01-18

申请号：US18255322

申请日：2021-12-03

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Poonam LATHIYA ,  Jing WANG

IPC: C04B35/26 ,  H01F1/34 ,  C04B35/64 ,  C04B35/63

CPC classification number: C04B35/265 ,  H01F1/344 ,  C04B35/64 ,  C04B35/6303 ,  C04B2235/3284 ,  C04B2235/3275 ,  C04B2235/3281 ,  C04B2235/549 ,  C04B2235/3274 ,  C04B2235/3279 ,  C04B2235/656

Abstract: A soft ferrite composition comprises a ferrimagnetic ceramic material having a crystal structure and a dopant in the crystal structure, wherein the ceramic material comprises an oxide including nickel, cobalt, zinc, and iron, wherein the dopant is selected from the group consisting of copper oxides, and wherein the dopant is present in the crystal structure at 0.1 to 20 weight percent based Non a total weight of the composition. The dopant can be CuO. The copper oxide doped Ni—Co—Zn ferrite can be used for very high frequency (VHF) and ultra high frequency (UHF) applications such antennas, isolators, and circulators.

公开(公告)号：US11866474B2

公开(公告)日：2024-01-09

申请号：US18069797

申请日：2022-12-21

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Jianfeng Cai ,  Sami Abdulkadir

IPC: C07K14/475 ,  A61P9/00 ,  A61K38/00

CPC classification number: C07K14/475 ,  A61P9/00 ,  A61K38/00

Abstract: Provided herein are novel VEGF mimics, pharmaceutical compositions thereof, and methods of their use in increasing or reducing angiogenesis.

公开(公告)号：US11865125B2

公开(公告)日：2024-01-09

申请号：US17554924

申请日：2021-12-17

Applicant: UNIVERSITY OF SOUTH FLORIDA ,  UNITED STATES DEPARTMENT OF VETERANS AFFAIRS

Inventor： Robert Vito Farese ,  Mini Paliyath Sajan ,  Margaret Genevieve Higgs

IPC: A61K31/675 ,  A61P25/28 ,  A61K33/242 ,  A61K31/122

CPC classification number: A61K31/675 ,  A61K31/122 ,  A61K33/242 ,  A61P25/28 ,  C12Y304/23046

Abstract: Provided herein are formulations effective for and methods of treating or preventing a neurodegenerative disorder in a subject in need thereof that can include administering an amount of an aPKC inhibitor to a subject in need thereof.