Sample clean up device and method
    36.
    发明授权

    公开(公告)号:US11617968B2

    公开(公告)日:2023-04-04

    申请号:US16642474

    申请日:2018-10-17

    Applicant: Biotage AB

    Abstract: The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

    ADSORBENT SYSTEM
    37.
    发明申请

    公开(公告)号:US20230091907A1

    公开(公告)日:2023-03-23

    申请号:US17993469

    申请日:2022-11-23

    Abstract: An adsorbent system including an enclosure having a cavity defining a humidity-controlled environment and a body having or defining a channel therein. The body is coupled to the enclosure such that a first end of the channel is in selective fluid communication with an ambient environment and a second end of the channel is in fluid communication with the humidity-controlled environment. The system further includes an adsorbent material in the channel, wherein the channel and adsorbent material are configured such that inlet fluid flowing from the first end to the second end through the channel is flowable over at least a portion of the adsorbent material, and such that outlet fluid flowing from the second end to the first end is directly flowable over a majority of the portion of the adsorbent material that is flowable over by the inlet fluid, The system further includes a valve system positioned at or adjacent to or in fluid communication with the first end of the channel. The valve system includes an inlet valve portion that is biased to a closed position to generally block a flow of inlet fluid therethrough and that is movable to an open position when a pressure in the channel is sufficiently low relative to a pressure in the ambient environment. The valve system further includes an outlet valve portion that is biased to a closed position to generally block a flow of outlet fluid therethrough and that is movable to an open position when the pressure in the channel is sufficiently high relative to the pressure in the ambient environment.

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