公开(公告)号：US11994455B2

公开(公告)日：2024-05-28

申请号：US17710244

申请日：2022-03-31

Applicant: OndaVia, Inc.

Inventor： Mark Charles Peterman ,  Merwan Benhabib

IPC: G01N15/06 ,  G01J3/44 ,  G01N15/075

CPC classification number: G01N15/06 ,  G01J3/4406 ,  G01N15/075

Abstract: An analyte in water is quantified by mixing an internal standard with a water sample. The sample is analyzed with a Raman spectrometer. The analysis includes mapping the signal from the Raman spectrometer to the quantity of said analyte. The mapping can include using a calibration curve, for example a multivariate calibration curve, that was previously prepared with the internal standard. In other examples, a sample is measured after addition of a known amount of the analyte.

公开(公告)号：US20240159588A1

公开(公告)日：2024-05-16

申请号：US18410593

申请日：2024-01-11

Applicant: Pendar Technologies, LLC

Inventor： Daryoosh VAKHSHOORI ,  Romain BLANCHARD ,  Peili CHEN ,  Masud AZIMI ,  Tobias MANSURIPUR ,  Kalyani KRISHNAMURTHY ,  Arran M. BIBBY ,  Fred R. HUETTIG, III ,  Gokhan ULU ,  Greg Vander Rhodes

IPC: G01J3/02 ,  G01J3/06 ,  G01J3/28 ,  G01J3/44 ,  G01K11/3213 ,  H01S3/00 ,  H01S3/094 ,  H01S3/108 ,  H01S3/30

CPC classification number: G01J3/0275 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0224 ,  G01J3/0237 ,  G01J3/0248 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0286 ,  G01J3/06 ,  G01J3/2823 ,  G01J3/44 ,  G01J3/4406 ,  G01J3/4412 ,  G01K11/3213 ,  H01S3/0014 ,  H01S3/094046 ,  H01S3/1086 ,  H01S3/302 ,  G01J2003/4424 ,  G01K11/324 ,  H01S3/0071

Abstract: A compact, portable Raman spectrometer makes fast, sensitive standoff measurements at little to no risk of eye injury or igniting the materials being probed. This spectrometer uses differential Raman spectroscopy and ambient light measurements to measure point-and-shoot Raman signatures of dark or highly fluorescent materials at distances of 1 cm to 10 m or more. It scans the Raman pump beam(s) across the sample to reduce the risk of unduly heating or igniting the sample. Beam scanning also transforms the spectrometer into an instrument with a lower effective safety classification, reducing the risk of eye injury. The spectrometer's long standoff range automatic focusing make it easier to identify chemicals through clear and translucent obstacles, such as flow tubes, windows, and containers. And the spectrometer's components are light and small enough to be packaged in a handheld housing or housing suitable for a small robot to carry.

公开(公告)号：US11977029B2

公开(公告)日：2024-05-07

申请号：US17480681

申请日：2021-09-21

Applicant: Dawatek, LLC

Inventor： Isaac W. Chadri ,  Edward Guen-Murray

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/65 ,  G01J3/44 ,  G01N2201/06113

Abstract: An Offset Raman imaging device and methods of use is disclosed and generally comprises a Raman laser and a XY plotter, wherein the Raman laser and the XY plotter are operably coupled to take Raman spectra scans of a region of interest.

公开(公告)号：US11976972B2

公开(公告)日：2024-05-07

申请号：US17612634

申请日：2020-05-21

Applicant: Ohio State Innovation Foundation

Inventor： Luis Rodriguez-Saona ,  Christopher Ball ,  Xin Rong Sia ,  Sanjay Krishna ,  Theodore James Ronningen

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/3563 ,  G01N21/359 ,  G01N33/02

CPC classification number: G01J3/0272 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/44 ,  G01N21/3563 ,  G01N21/359 ,  G01N33/02

Abstract: Disclosed herein are systems and devices for use in determining a level of a trait in an agriculture or food product sample. Further disclosed is a portable spectrometer system coupled with chemometric analysis methods to determine a level of a trait in an agriculture or food product sample, the portable spectrometer system comprising: a spectrometer; a sample stage adjacent the spectrometer; a motor coupled to the sample stage; and a system housing enclosing the motor and the spectrometer; wherein rotation of the motor rotates the sample stage, and wherein the motor is controllable in response to spectroscopy requirements.

公开(公告)号：US20240142380A1

公开(公告)日：2024-05-02

申请号：US18382930

申请日：2023-10-23

Applicant: SHIMADZU CORPORATION

Inventor： Ryuta SHIBUTANI

IPC: G01N21/65 ,  G01J3/44

CPC classification number: G01N21/65 ,  G01J3/4412 ,  G01N2021/656

Abstract: A micro-Raman device includes a first laser light source, a second laser light source, a first holder, a second holder, a first ND filter, and a second ND filter. The first laser light source and the second laser light source generate first laser light of a first wavelength and second laser light of a second wavelength, respectively. The second wavelength is different from the first wavelength. The first laser light and the second laser light proceed in a second direction orthogonal to a first direction while being separated from each other in the first direction. The first holder and the second holder are arranged overlapping each other in the second direction.

公开(公告)号：US20240110875A1

公开(公告)日：2024-04-04

申请号：US18155754

申请日：2023-01-18

Applicant: NATIONAL TSING HUA UNIVERSITY

Inventor： Shang-Da YANG ,  Chih-Hsuan Lu ,  Bo-Han Chen

IPC: G01N21/65 ,  G01J3/44 ,  G02F1/35

CPC classification number: G01N21/65 ,  G01J3/4412 ,  G02F1/3528 ,  G01N2021/653

Abstract: A coherent Raman spectro-microscopy system is configured for generating a spectro-microscopic image of a sample and includes a light source, a supercontinuum spectrum generator, a color filter assembly, and a spectro-microscopic assembly. The light source is for emitting at least one pulsed laser beam. The supercontinuum spectrum generator is for broadening the bandwidth of at least one pulsed laser beam. The color filter assembly is for filtering the bandwidth of at least one pulsed laser beam according to a predetermined bandwidth and converting at least one pulsed laser beam into a coherent spectro-microscopic laser beam. The sample is disposed in the spectro-microscopic assembly, and the spectro-microscopic assembly receives the coherent spectro-microscopic laser beam so that the coherent spectro-microscopic laser beam passes through the sample to generate the spectro-microscopic image of the sample.

公开(公告)号：US20240110833A1

公开(公告)日：2024-04-04

申请号：US18530698

申请日：2023-12-06

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Koyo WATANABE ,  Hisanari TAKAHASHI ,  Kyohei SHIGEMATSU ,  Takashi INOUE

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/28

CPC classification number: G01J3/4412 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/2823

Abstract: A dispersion measurement apparatus includes a pulse forming unit, a correlation optical system, a beam splitter, an operation unit, an imaging unit, a spatial filter unit, and a photodetector. The pulse forming unit forms a light pulse train including light pulses having time differences and different center wavelengths. The beam splitter branches the light pulse train passed through a measurement object. The imaging unit disperses one light pulse train and images each light pulse. The spatial filter unit extracts light of a partial region of the other light pulse train. The correlation optical system outputs correlation light including a cross-correlation or an autocorrelation of the extracted light. The photodetector detects a temporal waveform of the correlation light. The operation unit estimates a wavelength dispersion amount in the measurement object based on a feature value of the temporal waveform.

公开(公告)号：US11946803B1

公开(公告)日：2024-04-02

申请号：US18523263

申请日：2023-11-29

Applicant: ANSWERAY INC.

Inventor： Seong Ho Cho

IPC: G01J3/44 ,  G01J3/02 ,  G01N21/65

CPC classification number: G01J3/0208 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/4412 ,  G01N21/65

Abstract: Disclosed is Raman spectroscopy equipment including a light source unit configured to generate excitation light, a first optical fiber configured to transmit the excitation light received from the light source unit, a light radiation unit configured to receive the excitation light from the first optical fiber, a target material located near the light radiation unit, the target material being configured to receive the excitation light from the light radiation unit and to generate first scattered light, a light focusing unit configured to concentrate the first scattered light in the vicinity of the target material and the light radiation unit and to change the first scattered light to second scattered light, a second optical fiber configured to transmit the second scattered light received from the light focusing unit, and a spectroscopy unit configured to convert the second scattered light received from the second optical fiber into an electrical signal.

公开(公告)号：US11940371B2

公开(公告)日：2024-03-26

申请号：US18069281

申请日：2022-12-21

Applicant: Life Technologies Corporation

Inventor： Gregory Kaduchak ,  Michael Ward

IPC: G01N15/14 ,  B01L3/00 ,  G01J3/44 ,  G01N15/00 ,  G01N15/02 ,  G01N15/10 ,  G01N21/53 ,  G01N21/64

CPC classification number: G01N15/1436 ,  B01L3/502761 ,  G01J3/4406 ,  G01N15/0227 ,  G01N15/0272 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1456 ,  G01N15/1459 ,  G01N15/1468 ,  G01N15/147 ,  G01N21/532 ,  G01N21/6456 ,  B01L2200/0652 ,  B01L2400/082 ,  G01N2015/0003 ,  G01N2015/0011 ,  G01N2015/03 ,  G01N2015/1006 ,  G01N2015/1081 ,  G01N2015/1415 ,  G01N2015/142 ,  G01N2015/1422 ,  G01N2015/1438 ,  G01N2015/1445 ,  G01N2015/1452 ,  G01N2015/149

Abstract: The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

公开(公告)号：US20240094132A1

公开(公告)日：2024-03-21

申请号：US18516429

申请日：2023-11-21

Applicant: Jonathan David Waldern

Inventor： Jonathan David Waldern

IPC: G01N21/65 ,  G01J3/44 ,  G02B1/00

CPC classification number: G01N21/658 ,  G01J3/44 ,  G02B1/005

Abstract: A general purpose sensor architecture integrating a surface enhanced Raman spectroscopy (SERS) substrate, a diffractive laser beam delivery substrate and a diffractive infrared detection substrate is provided that can be used to implement a low-cost, compact lab-on-a-chip biosensor that can meet the needs of large-scale infectious disease testing. The sensor architecture can also be used in any other application in which molecules present in the liquid, gaseous or solid phases need to be characterized reliably, cost-effectively and with minimal intervention by highly skilled personnel.