Surface-enhanced raman scattering biosensor

    公开(公告)号:US11852588B2

    公开(公告)日:2023-12-26

    申请号:US17983136

    申请日:2022-11-08

    CPC classification number: G01N21/658 G01J3/44 G02B1/005

    Abstract: A general purpose sensor architecture integrating a surface enhanced Raman spectroscopy (SERS) substrate, a diffractive laser beam delivery substrate and a diffractive infrared detection substrate is provided that can be used to implement a low-cost, compact lab-on-a-chip biosensor that can meet the needs of large-scale infectious disease testing. The sensor architecture can also be used in any other application in which molecules present in the liquid, gaseous or solid phases need to be characterized reliably, cost-effectively and with minimal intervention by highly skilled personnel.

    APPARATUS FOR COPYING A HOLOGRAM
    3.
    发明申请
    APPARATUS FOR COPYING A HOLOGRAM 审中-公开
    用于复制HOLOGRAM的装置

    公开(公告)号:US20150177688A1

    公开(公告)日:2015-06-25

    申请号:US14409317

    申请日:2013-06-17

    Abstract: A holographic recording apparatus having a source of illumination, a master hologram containing at least one hologram lamina overlaying, a copy substrate containing a holographic recording medium, and a voltage generator for applied a voltage across at least one of the master hologram and the copy substrate. The master hologram diffracts the illumination light into zero order light and diffracted light which interfere in the copy substrate to form a copy of the master hologram. The source of illumination is applied for a predefined exposure time during which the voltage varies the refractive index modulation of at least one of the master hologram and the copy hologram.

    Abstract translation: 具有照明源的全息记录装置,包含至少一个全息图层叠的主全息图,含有全息记录介质的复制基板和用于施加电压的电压发生器,所述电压跨越主全息图和复制基板中的至少一个 。 主全息图将照明光衍射成零级光和衍射光,其干涉复印基板以形成主全息图的副本。 施加照明源以预定的曝光时间,在该预定曝光时间期间,电压改变主全息图和复制全息图中的至少一个的折射率调制。

    Compact wearable display
    4.
    发明申请
    Compact wearable display 有权
    紧凑可穿戴显示屏

    公开(公告)号:US20130101253A1

    公开(公告)日:2013-04-25

    申请号:US13317468

    申请日:2011-10-19

    CPC classification number: G02B27/017 G02B6/0028

    Abstract: There is provided a wearable display comprising a light source emitting light of a first wavelength; a first SBG device having a front side and a rear side; first and second transparent plates sandwiching said SBG device; independently switchable transparent electrode elements applied to the opposing surfaces of said transparent plates, a means for spatio-temporally modulating light from the light source to provide image light and a means for coupling the image light into the light guide formed by the two transparent plates and the SBG device. The SBG device comprises a multiplicity of selectively switchable grating regions. The SBG device diffracts image into the pupil of an eye.

    Abstract translation: 提供了一种可穿戴式显示器,其包括发射第一波长的光的光源; 具有前侧和后侧的第一SBG装置; 夹持所述SBG装置的第一和第二透明板; 施加到所述透明板的相对表面的可独立切换的透明电极元件,用于时空调制来自光源的光以提供图像光的装置和用于将图像光耦合到由两个透明板形成的导光体中的装置;以及 SBG设备。 SBG器件包括多个可选择切换的光栅区域。 SBG装置将图像衍射成眼睛的瞳孔。

    WEARABLE DATA DISPLAY
    7.
    发明申请
    WEARABLE DATA DISPLAY 审中-公开
    数据显示

    公开(公告)号:US20140204455A1

    公开(公告)日:2014-07-24

    申请号:US14240643

    申请日:2012-08-22

    Abstract: A transparent wearable data display having a source of collimated light a deflector for deflecting the collimated light into a scanned beam, and a first array including one column and integer N rows of switchable grating elements sandwiched between first and second parallel transparent substrates. The substrates together functioning as a first light guide, and a second array including M columns and N rows of switchable grating elements sandwiched between third and fourth parallel transparent substrates which together function as a second lightguide. Transparent electrodes are applied to opposing substrates. A first coupling for directing the scanned beam into a first TIR light path of the first lightguide along the first array column; and a second coupling for directing the first TIR light into a second TIR path of the second lightguide along a row of elements of the second array.

    Abstract translation: 一种具有准直光源的透明耐磨数据显示器,用于将准直光偏转成扫描光束;以及第一阵列,其包括夹在第一和第二平行透明基板之间的一列和整排N行可切换光栅元件。 一起用作第一光导的基板和包括M列和N行可切换光栅元件的第二阵列,其夹在第三和第四平行透明基板之间,它们一起用作第二光导。 将透明电极施加到相对的基板上。 用于将扫描光束沿第一阵列列引导到第一光导的第一TIR光路中的第一耦合; 以及第二联接器,用于沿着第二阵列的一列元件将第一TIR光引导到第二光导的第二TIR路径。

    COMPACT HOLOGRAPHIC ILLUMINATION DEVICE
    9.
    发明申请
    COMPACT HOLOGRAPHIC ILLUMINATION DEVICE 有权
    紧凑的全息照明设备

    公开(公告)号:US20100284180A1

    公开(公告)日:2010-11-11

    申请号:US12444315

    申请日:2006-10-27

    Abstract: There is provided a colour sequential illumination device comprising in series: first and second light sources; a condenser lens; and a grating device. The grating device comprises at least one Bragg grating. The condenser lens directs light from the first and second sources into the grating device at first and second incidence angles respectively. The grating device diffracts light from the first and second sources into a common direction. Desirably, the Bragg gratings are Electrically Switchable Bragg Gratings. In one embodiment of the invention the light sources are Light Emitting Diodes. Alternatively lasers may be used.

    Abstract translation: 提供了一种串联的彩色顺序照明装置,包括:第一和第二光源; 聚光透镜; 和光栅装置。 光栅装置包括至少一个布拉格光栅。 聚光透镜分别以第一和第二入射角将来自第一和第二光源的光引导到光栅装置中。 光栅装置将来自第一和第二光源的光衍射成共同的方向。 理想地,布拉格光栅是电可切换布拉格光栅。 在本发明的一个实施例中,光源是发光二极管。 或者可以使用激光器。

    Surface-enhanced raman scattering biosensor

    公开(公告)号:US11513077B2

    公开(公告)日:2022-11-29

    申请号:US17500700

    申请日:2021-10-13

    Abstract: A general purpose sensor architecture integrating a surface enhanced Raman spectroscopy (SERS) substrate, a diffractive laser beam delivery substrate and a diffractive infrared detection substrate is provided that can be used to implement a low-cost, compact lab-on-a-chip biosensor that can meet the needs of large-scale infectious disease testing. The sensor architecture can also be used in any other application in which molecules present in the liquid, gaseous or solid phases need to be characterized reliably, cost-effectively and with minimal intervention by highly skilled personnel.

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