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公开(公告)号：US20170042861A1
公开(公告)日：2017-02-16
申请号：US15230633
申请日：2016-08-08
Applicant: Insys Development Company, Inc.
CPC classification number: A61K31/4178 , A61K9/006 , A61K9/08 , A61K47/10 , A61K47/12
Abstract: The invention is directed to sublingual spray formulations containing ondansetron, a pharmaceutically acceptable salt thereof, and a solvent consisting of ethanol and glycerin, suitable for administration to humans, and methods for treatment with sublingual formulations.
Abstract translation: 本发明涉及含有昂丹司琼，其药学上可接受的盐和适用于给予人的由乙醇和甘油组成的溶剂的舌下喷雾制剂，以及用舌下制剂治疗的方法。
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公开(公告)号：US20160361307A1
公开(公告)日：2016-12-15
申请号：US15246343
申请日：2016-08-24
Applicant: Insys Development Company, Inc.
Inventor： Kiran P. Amancha , Chandeshwari S. Chilampalli , Venkat R. Goskonda
IPC: A61K31/485 , A61K47/10 , A61K9/00
CPC classification number: A61K31/485 , A61K9/006 , A61K31/085 , A61K31/198 , A61K31/375 , A61K31/4748 , A61K47/10 , A61K47/20 , A61K2300/00
Abstract: The invention provides sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention further provides sublingual formulations containing buprenorphine and naloxone, pharmaceutically acceptable salts thereof or derivatives thereof. The invention further provides a method of treating pain or opioid dependence by administering sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof to a patient in need thereof.
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公开(公告)号：US20160199294A1
公开(公告)日：2016-07-14
申请号：US15076080
申请日：2016-03-21
Applicant: Insys Development Company, Inc.
Inventor： Kiran Amancha , Shivani Chilampalli , Thrimoorthy Potta , Ning Shan , Ningxin Yan , Onkar N. Singh , Venkat R. Goskonda
IPC: A61K9/00 , A61K47/18 , A61K31/485
CPC classification number: A61K9/006 , A61K31/485 , A61K47/10
Abstract: The invention provides storage stable sublingual formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering the sublingual formulations of the present invention to a patient in need thereof.
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公开(公告)号：US20160193142A1
公开(公告)日：2016-07-07
申请号：US15042999
申请日：2016-02-12
Applicant: Insys Development Company, Inc.
Inventor： S. George Kottayil , Venkat R. Goskonda , Zhongyuan Zhu , Linet Kattookaran , Neha Parikh
IPC: A61K9/00 , A61K31/4468
CPC classification number: A61K31/4468 , A61K9/0056 , A61K9/006 , A61K31/435 , A61K31/445 , A61K47/10 , A61M11/00
Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
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公开(公告)号：US11077075B2
公开(公告)日：2021-08-03
申请号：US16242101
申请日：2019-01-08
Applicant: Insys Development Company, Inc.
Inventor： Eshwaran Narayanan , Rajesh Wakaskar , Chandeshwari Chilampalli , Thrimoorthy Potta , Venkat R. Goskonda
Abstract: The present invention is directed to methods of stabilizing a pharmaceutical composition comprising epinephrine containing the steps filling a container, capping the container, assembling the container and placing the assembled capped container (assembled device) in a secondary packaging system.
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Patent Agency Ranking
公开(公告)号：US20190209517A1
公开(公告)日：2019-07-11
申请号：US16242098
申请日：2019-01-08
Applicant: Insys Development Company, Inc.
Inventor： Eshwaran Narayanan , Rajesh Wakaskar , Rachana Inavolu , Thrimoorthy Potta , Venkat R. Goskonda
CPC classification number: A61K31/352 , A61J1/00 , A61K9/0053 , A61K47/10 , A61K47/14 , A61K47/183
Abstract: The present invention is directed to methods of stabilizing an oral pharmaceutical composition comprising dronabinol containing the steps filling a container, capping the container and placing the capped container in a secondary packaging system.
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公开(公告)号：US20190192428A1
公开(公告)日：2019-06-27
申请号：US16282817
申请日：2019-02-22
Applicant: Insys Development Company, Inc.
Inventor： Venkat R. Goskonda , Ashok Chavan , Amit Kokate , Howard Gill
IPC: A61K9/00 , A61K31/353 , A61K47/10 , A61K9/08 , A61K9/48
CPC classification number: A61K9/0053 , A61K9/08 , A61K9/4858 , A61K31/353 , A61K47/10
Abstract: Oral cannabinoid formulations, including an aqueous-based oral dronabinol solution, that are stable at room or refrigerated temperatures and may possess improved in vivo absorption profiles with faster onset and lower inter-subject variability.
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公开(公告)号：US20190167581A1
公开(公告)日：2019-06-06
申请号：US16240632
申请日：2019-01-04
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Craig Bastian , Ningxin Yan , Venkat Goskonda , Chandeshwari Chilampalli , Rachana Inavolu , Eshwaran Narayanan
IPC: A61K9/08 , A61P37/08 , A61K31/137 , A61K9/00 , A61K9/12 , A61K47/02 , A61K47/18 , A61K47/10 , A61K47/12
Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.
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公开(公告)号：US10265293B2
公开(公告)日：2019-04-23
申请号：US15132896
申请日：2016-04-19
Applicant: Insys Development Company, Inc.
Inventor： Venkat R. Goskonda , Ashok Chavan , Amit Kokate , Howard Gill
IPC: A61K31/352 , A61K9/08 , A61K36/185 , A61K9/00 , A61K31/353 , A61K47/10
Abstract: Oral cannabinoid formulations, including an aqueous-based oral dronabinol solution, that are stable at room or refrigerated temperatures and may possess improved in vivo absorption profiles with faster onset and lower inter-subject variability.
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公开(公告)号：US20190106232A1
公开(公告)日：2019-04-11
申请号：US16116020
申请日：2018-08-29
Applicant: Insys Development Company, Inc.
Inventor： Simon Freed , David C. Woodruff
Abstract: A medical vial filling system is adapted to fill a medical vial with a solution and cap the filled medical vial. A purging system includes a manifold disposed between a filling station and a capping station. The manifold includes a filling inlet port and a plurality of output ports. The output ports are positioned in a space proximate the filling station and in a space over the transport mechanism. A stoppering block includes a capping chamber for receiving a bushing positioned at the capping station. The stoppering block comprises a stoppering inlet port, a first nozzle opening into the capping chamber and a second nozzle extending into the capping chamber and directed into the medical vial when the medical vial is position in the capping station. A supply of non-reactive gas at the filling inlet port directs flow of the non-reactive gas out the manifold outlet ports to evacuate air and substitute the non-reactive gas in the filled medical vial and at the stoppering inlet port directs flow of the non-reactive gas in a flood zone surround a space above the medical vials when the medical vial is positioned in the capping station and in a stream directed into the medical vial when the medical vial is positioned in the capping station.
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