公开(公告)号：US11839861B2

公开(公告)日：2023-12-12

申请号：US17149613

申请日：2021-01-14

Applicant: Genzyme Corporation

Inventor： Rahul Godawat ,  Veena Warikoo ,  Rohan Patil ,  Konstantin Konstantinov ,  Venkat Kishore Ryakala

IPC: B01J20/281 ,  B01J20/34 ,  B01D15/18 ,  B01D15/20 ,  B01D15/32 ,  B01D15/34 ,  B01D15/36 ,  B01J39/26 ,  B01D15/38 ,  B01J20/26 ,  B01J41/12 ,  B01J41/20 ,  C07K1/16 ,  C07K1/22 ,  A61L2/08 ,  C07K1/18

CPC classification number: B01J20/3441 ,  A61L2/081 ,  B01D15/1864 ,  B01D15/20 ,  B01D15/327 ,  B01D15/34 ,  B01D15/362 ,  B01D15/363 ,  B01D15/3804 ,  B01J20/265 ,  B01J20/281 ,  B01J39/26 ,  B01J41/12 ,  B01J41/20 ,  C07K1/16 ,  C07K1/18 ,  C07K1/22 ,  Y10T29/49826

Abstract: Provided herein are methods of reducing bioburden of (e.g., sterilizing) a chromatography resin that include exposing a container including a composition including a chromatography resin and at least one antioxidant agent and/or chelator to a dose of gamma-irradiation sufficient to reduce the bioburden of the container and the chromatography resin, where the at least one antioxidant agent and/or chelator are present in an amount sufficient to ameliorate the loss of binding capacity of the chromatography resin after/upon exposure to the dose of gamma-irradiation. Also provided are reduced bioburden chromatography columns including the reduced bioburden chromatography resin, compositions including a chromatography resin and at least one chelator and/or antioxidant agent, methods of performing reduced bioburden column chromatography using one of these reduced bioburden chromatography columns, and integrated, closed, and continuous processes for reduced bioburden manufacturing of a purified recombinant protein.

公开(公告)号：US11713256B2

公开(公告)日：2023-08-01

申请号：US16343298

申请日：2017-10-19

Applicant: H2nanO Inc.

Inventor： Timothy Michael Carter Leshuk ,  Zachary William Young ,  Frank Gu

IPC: C02F1/28 ,  B01J20/06 ,  B01J20/10 ,  B01J20/20 ,  B01J20/28 ,  B01J20/34 ,  B01J37/02 ,  C02F1/32 ,  C02F1/72 ,  C02F1/00 ,  C02F1/44 ,  C02F1/467 ,  C02F1/52 ,  C02F103/00 ,  C02F1/48

CPC classification number: C02F1/288 ,  B01J20/06 ,  B01J20/103 ,  B01J20/20 ,  B01J20/2803 ,  B01J20/28009 ,  B01J20/28026 ,  B01J20/28035 ,  B01J20/3433 ,  B01J20/3441 ,  B01J20/3475 ,  B01J37/0215 ,  C02F1/32 ,  C02F1/725 ,  C02F1/001 ,  C02F1/281 ,  C02F1/283 ,  C02F1/44 ,  C02F1/4672 ,  C02F1/488 ,  C02F1/52 ,  C02F2103/007 ,  C02F2303/16 ,  C02F2303/18 ,  C02F2305/08 ,  C02F2305/10 ,  Y02A20/212

Abstract: A composite material for use in water treatment. The composite material includes a porous matrix including a resin capable of retaining a catalyst and magnetic material therein, and includes a density regulating portion disposed therein. The catalyst is capable of facilitating a chemical reaction involving a contaminants in the water. The magnetic material and density regulating portion can be used to separate the composite material from treated water. Systems and methods of use involving passive water treatment, continuous water treatment, solar light exposure, UV light exposure, and electrochemical cells, employing photochemical, electrochemical, and photoelectrochemical reactions are described. Methods of manufacture are described.

公开(公告)号：US20170368494A1

公开(公告)日：2017-12-28

申请号：US15536329

申请日：2016-01-06

Applicant: Dow Global Technologies LLC

Inventor： Matthew L. Rodgers ,  Brandon J. Kern ,  Scott T. Matteucci ,  H. Robert Goltz ,  Daryl J. Gisch

IPC: B01D53/08 ,  B01J20/26 ,  C10L3/10

CPC classification number: B01D53/08 ,  B01D53/02 ,  B01D2253/202 ,  B01D2256/24 ,  B01D2256/245 ,  B01D2257/7022 ,  B01D2259/40094 ,  B01J20/261 ,  B01J20/264 ,  B01J20/265 ,  B01J20/267 ,  B01J20/28011 ,  B01J20/28066 ,  B01J20/3425 ,  B01J20/3441 ,  C10L3/10 ,  C10L3/101

Abstract: A method for separating natural gas liquids (NGLs) from a hydrocarbon gas mixture containing natural gas liquids and methane, comprising the steps of: i) providing a bed of adsorbent selective for NGLs over methane; ii) passing a hydrocarbon gas mixture containing methane and NGL through the bed of adsorbent to at least partially remove NGLs from the gas mixture to produce: (a) NGL-loaded adsorbent and (b) NGL-depleted hydrocarbon gas mixture; iii) recovering the NGL-depleted hydrocarbon gas mixture; iv) regenerating the NGL-loaded adsorbent by at least partially removing NGLs from the adsorbent; and v) sequentially repeating steps (ii) and (iii) using regenerated adsorbent from step (iv).

公开(公告)号：US09808789B2

公开(公告)日：2017-11-07

申请号：US15305336

申请日：2015-04-16

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Jia Min Chin ,  Jin Yang ,  Han Yang Tan ,  Yin Ngai Sum ,  Siok Wei Tay

IPC: B01J20/34 ,  B01J20/06 ,  B01J20/08 ,  B01D53/14

CPC classification number: B01J20/3483 ,  B01D53/1425 ,  B01D53/1462 ,  B01D2252/2023 ,  B01D2252/20405 ,  B01D2252/20421 ,  B01D2252/20426 ,  B01D2252/20484 ,  B01D2252/20489 ,  B01D2252/30 ,  B01D2252/504 ,  B01D2252/604 ,  B01J20/06 ,  B01J20/08 ,  B01J20/3441

Abstract: The invention relates to methods for regenerating a used sorbent having a gas adsorbate adsorbed thereto. In particular, the used sorbent comprises liquid marbles. The liquid in the liquid marbles is comprised of a material or mixture of materials that selectively removes unwanted gaseous component in the gas to be purified.

公开(公告)号：US09630165B2

公开(公告)日：2017-04-25

申请号：US14629315

申请日：2015-02-23

Applicant: Genzyme Corporation

Inventor： Rahul Godawat ,  Veena Warikoo ,  Rohan Patil ,  Konstantin Konstantinov ,  Venkat Kishore Ryakala

IPC: B01J20/34 ,  B01D15/36 ,  B01D15/38 ,  B01J20/26 ,  B01J20/281 ,  B01J41/12 ,  B01J41/20 ,  C07K1/16 ,  C07K1/22 ,  A61L2/08 ,  C07K1/18 ,  B01D15/18 ,  B01D15/20 ,  B01D15/32 ,  B01D15/34 ,  B01J39/26

CPC classification number: B01J20/3441 ,  A61L2/081 ,  B01D15/1864 ,  B01D15/20 ,  B01D15/327 ,  B01D15/34 ,  B01D15/362 ,  B01D15/363 ,  B01D15/3804 ,  B01J20/265 ,  B01J20/281 ,  B01J39/26 ,  B01J41/12 ,  B01J41/20 ,  C07K1/16 ,  C07K1/18 ,  C07K1/22 ,  Y10T29/49826

Abstract: Provided herein are methods of reducing bioburden of (e.g., sterilizing) a chromatography resin that include exposing a container including a composition including a chromatography resin and at least one antioxidant agent and/or chelator to a dose of gamma-irradiation sufficient to reduce the bioburden of the container and the chromatography resin, where the at least one antioxidant agent and/or chelator are present in an amount sufficient to ameliorate the loss of binding capacity of the chromatography resin after/upon exposure to the dose of gamma-irradiation. Also provided are reduced bioburden chromatography columns including the reduced bioburden chromatography resin, compositions including a chromatography resin and at least one chelator and/or antioxidant agent, methods of performing reduced bioburden column chromatography using one of these reduced bioburden chromatography columns, and integrated, closed, and continuous processes for reduced bioburden manufacturing of a purified recombinant protein.

公开(公告)号：US20160355743A1

公开(公告)日：2016-12-08

申请号：US15107678

申请日：2014-08-05

Applicant: DOW GLOBAL TECHNOLOGIES LLC

Inventor： Scott T. Matteucci ,  H. Robert Goltz ,  Ajay N. Badhwar ,  Nicholas J. Shurgott

IPC: C10L3/10 ,  B01J20/28 ,  B01J20/26 ,  B01J20/30 ,  B01D53/047 ,  B01D53/04

CPC classification number: C10L3/101 ,  B01D53/0462 ,  B01D53/047 ,  B01D2253/202 ,  B01D2253/306 ,  B01D2253/308 ,  B01D2256/245 ,  B01D2257/7022 ,  B01J20/20 ,  B01J20/267 ,  B01J20/28057 ,  B01J20/28066 ,  B01J20/28085 ,  B01J20/28092 ,  B01J20/3078 ,  B01J20/3416 ,  B01J20/3425 ,  B01J20/3441 ,  C10L2290/542

Abstract: A method is disclosed for the separation of ethane and heavier hydrocarbons or propane and heavier hydrocarbons from natural gas to provide a methane-rich natural gas stream and less volatile natural gas liquids (NGLs). This method provides for the use of a regenerable adsorbent media comprising a porous cross-linked polymeric adsorbent, a pyrolized macroporous polymer, or mixtures thereof, which is regenerated by a pressure swing adsorption (PSA) process, temperature swing adsorption (TSA) process, or combination of the two. Said regeneration step may be operated as a batch process, a semi-continuous process, or preferably as a continuous process.

Abstract translation: 公开了一种用于从天然气分离乙烷和较重烃或丙烷和较重烃的方法，以提供富含甲烷的天然气流和较不易挥发的天然气液体（NGL）。 该方法提供使用可再生的吸附剂介质，其包括通过变压吸附（PSA）方法，变温吸附（TSA）方法再生的多孔交联聚合物吸附剂，热解的大孔聚合物或其混合物， 或两者的组合。 所述再生步骤可以作为间歇法，半连续法或优选作为连续法进行操作。

公开(公告)号：US20150367280A1

公开(公告)日：2015-12-24

申请号：US14840740

申请日：2015-08-31

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Ming-Shiann SHIH ,  Jau-Chyn HUANG

IPC: B01D53/26 ,  B01D53/04 ,  B01D53/28

CPC classification number: B01D53/261 ,  B01D53/0438 ,  B01D53/06 ,  B01D53/28 ,  B01D2253/106 ,  B01D2257/80 ,  B01D2259/40083 ,  B01D2259/4009 ,  B01D2259/40096 ,  B01D2259/4508 ,  B01J20/02 ,  B01J20/06 ,  B01J20/10 ,  B01J20/18 ,  B01J20/20 ,  B01J20/3433 ,  B01J20/3441 ,  B01J2220/42

Abstract: A dehumidification device and an electrified desorption device thereof are provided. The electrified desorption device includes a conductive water-absorbing material containing titanosilicates; a conductive layer containing a metal component or a mixture of the metal component and graphite, attached to end surfaces at two sides of the water-absorbing material; a pair of electrode structures, coupled to the two sides of the water-absorbing material respectively and each having multiple sub-electrodes insulated from each other; and a voltage source, coupled to the pair of electrode structures. The electrodes are coupled to the conductive water-absorbing material, and the conductive water-absorbing material is directly electrified with a current, so that the conductive water-absorbing material generates heat to achieve a desorption effect, and further maintains a re-adsorbing capability to continue operation.

Abstract translation: 本发明提供一种除湿装置及其电气解吸装置。 带电解吸装置包括含有钛硅酸盐的导电吸水材料; 包含附着在吸水材料两侧的端面的金属成分或金属成分与石墨的混合物的导电层; 一对电极结构，分别耦合到吸水材料的两侧，并且每个具有彼此绝缘的多个子电极; 以及耦合到所述一对电极结构的电压源。 电极与导电性吸水材料接合，导电性吸水材料通过电流直接通电，导电性吸水材料产生热量以达到解吸作用，进一步保持再吸附能力 继续操作。

公开(公告)号：US20150139862A1

公开(公告)日：2015-05-21

申请号：US14084893

申请日：2013-11-20

Applicant: L'Air Liquide Societe Anonyme Pour l'Etude et l'Exploitation des Procedes Georges Claude

Inventor： Yudong CHEN ,  Christian MONEREAU ,  Edgar S. SANDERS, JR. ,  Pascal TESSIER

IPC: F01N3/28

CPC classification number: F01N3/2803 ,  B01D53/0438 ,  B01D53/62 ,  B01D53/82 ,  B01D2252/204 ,  B01D2253/102 ,  B01D2253/104 ,  B01D2253/106 ,  B01D2253/108 ,  B01D2253/204 ,  B01D2253/304 ,  B01D2253/34 ,  B01D2257/504 ,  B01J20/08 ,  B01J20/10 ,  B01J20/18 ,  B01J20/205 ,  B01J20/226 ,  B01J20/28004 ,  B01J20/2803 ,  B01J20/28035 ,  B01J20/2804 ,  B01J20/3441 ,  Y02A50/2342 ,  Y02C10/04 ,  Y02C10/08

Abstract: A structured adsorbent sheet, is provided including a nano-adsorbent powder, and a binder material, wherein the nano-adsorbent powder is combined with the binder material to form an adsorbent material, and a porous electrical heating substrate, wherein the adsorbent material is applied to the porous electrical heating substrate thereby forming a structured adsorbent sheet.A structured adsorbent module is provided, including a plurality of stacked structured adsorbent sheets, configured to produce a plurality of fluid passages, wherein the plurality of fluid passages have a cross-sectional shape in the direction of a fluid stream. The structured adsorbent module may have a cross-sectional shape that is trapezoidal, rectangle, square, triangular or sinusoidal.A structured adsorbent bed is provided, including a plurality of modules, stacking the modules, thereby providing a plurality of process fluid passages, and a process fluid inlet and a process fluid outlet, in fluid communication with the plurality of process fluid.

Abstract translation: 提供一种结构化吸附片，其包括纳米吸附剂粉末和粘合剂材料，其中纳米吸附剂粉末与粘合剂材料组合以形成吸附材料，以及多孔电加热基材，其中施加吸附剂材料 到多孔电加热基板，从而形成结构化的吸附片。 提供了一种结构化吸附剂模块，其包括多个层叠的结构化吸附片，其被配置为产生多个流体通道，其中多个流体通道在流体流的方向上具有横截面形状。 结构化吸附剂组件可以具有梯形，矩形，正方形，三角形或正弦曲线的横截面形状。 提供了一种结构化的吸附床，包括多个模块，堆叠模块，从而提供多个工艺流体通道，以及与多个工艺流体流体连通的工艺流体入口和工艺流体出口。

公开(公告)号：US20150101483A1

公开(公告)日：2015-04-16

申请号：US14511611

申请日：2014-10-10

Applicant: MeadWestvaco Corporation

Inventor： John D. PERRY ,  Paula S. WALMET

IPC: B01J20/28 ,  B01J20/20 ,  B01D53/06

CPC classification number: B01J20/28069 ,  B01D53/06 ,  B01D2253/102 ,  B01D2253/108 ,  B01D2253/20 ,  B01D2253/311 ,  B01D2253/3425 ,  B01D2257/704 ,  B01J20/20 ,  B01J20/28011 ,  B01J20/2803 ,  B01J20/28045 ,  B01J20/3007 ,  B01J20/3416 ,  B01J20/3441 ,  Y10T428/24149

Abstract: An adsorbent media has a pore volume/media volume of at least about 0.12 cc pore volume/cc media, a specific heat capacity of less than about 2.9 J/cc pore volume, and a pressure drop of less than about 4.0 inH2O/ft media at a superficial air velocity of about 500 ft/min, wherein the adsorbent media is in a concentrator system. An extruded honeycomb adsorbent media has a cell density of more than about 200 cells per square inch (cspi), % open area of at least about 50%, an activated carbon content of at least about 50% by weight based on total weight, and a pressure drop of less than about 4.0 inH2O/ft media at a superficial fluid velocity of about 500 ft/min.

Abstract translation: 吸附介质具有至少约0.12cc孔体积/ cc介质的孔体积/介质体积，小于约2.9J / cc孔体积的比热容和小于约4.0英寸H 2 O / ft介质的压降 以约500ft / min的表观空气速度，其中吸附剂介质处于浓缩器系统中。 挤出的蜂窝状吸附介质的细胞密度大于约200个细胞/平方英寸（cspi），％开放面积至少为约50％，活性炭含量为至少约50重量％，基于总重量，以及 以约500英尺/分钟的表面流体速度的小于约4.0英寸的H 2 O / ft介质的压降。

公开(公告)号：US08728323B2

公开(公告)日：2014-05-20

申请号：US12425569

申请日：2009-04-17

Applicant: Nigel Willis Brown ,  Edward P. L. Roberts ,  Amy Jane Eccleston ,  June Lilian Richards

Inventor： Kenneth Thomas Eccleston ,  Nigel Willis Brown ,  Edward P. L. Roberts

IPC: C02F1/28

CPC classification number: B01J20/20 ,  B01J20/3416 ,  B01J20/3441 ,  C01B32/22 ,  C02F1/281 ,  C02F1/288 ,  C02F2303/16

Abstract: An adsorbent particulate product for treating contaminated fluid and capable of electrochemical regeneration. The product includes unexpanded intercalated graphite in particulate form, in the form of flakes or in powder form.

Abstract translation: 一种用于处理受污染流体并能够进行电化学再生的吸附剂颗粒产品。 该产品包括颗粒形式的未膨胀的插层石墨，呈片状或粉末形式。