公开(公告)号：US20160175833A1

公开(公告)日：2016-06-23

申请号：US15055169

申请日：2016-02-26

Applicant: Panasonic Healthcare Holdings Co., Ltd.

Inventor： Koichi KOBAYASHI ,  Yasuhiko YOKOI ,  Hironobu SEKINE

IPC: B01L1/02

CPC classification number: B01L1/025 ,  B01L1/04 ,  B01L2200/028 ,  B01L2200/087 ,  B01L2200/141 ,  B01L2300/1894 ,  B25J21/02 ,  C12M37/00

Abstract: An isolator system including: a box-shaped body case having, in an interior thereof, a work space for operation in a sterile environment and also having, in a front surface thereof, an insertion portion into which a worker's arm is inserted; and an air-conditioning portion configured to supply gas in the work space of the body case or to discharge gas in the work space, a bottom of the work space being configured with a work plate, a discharge path configured to discharge gas in the work space being formed below the work plate, the work plate being configured with first and second work plates obtained by dividing the work plate into right and left parts, a receiving portion being located below the first work plate, the receiving portion being arranged extending towards the second work plate on a side edge of the first work plate, the side edge of the first work plate being in contact with the second work plate, a side edge of the second work plate for being in contact with the first work plate being placed detachably on the receiving portion.

Abstract translation: 一种隔离器系统，包括：箱体主体壳体，其内部具有用于在无菌环境中操作的工作空间，并且在其前表面中还具有插入工人的手臂的插入部分; 以及空调部，其构造成在所述主体壳体的工作空间内供给气体，或者在所述作业空间中排出气体，所述作业空间的底部具有工作板，排出路径，其被配置为在所述作业中排出气体 在工作板下面形成空间，工作板配置有通过将工作板分成左右部分而获得的第一和第二工作板，位于第一工作板下方的接纳部分， 第二工作板与第一工作板的侧边缘接触的第二工作板的侧边缘，与第一工作板接触的第二工作板的侧边缘被可拆卸地放置 在接收部分。

公开(公告)号：US09314787B2

公开(公告)日：2016-04-19

申请号：US10497952

申请日：2002-12-13

Applicant: Jean-Yves Porret

Inventor： Jean-Yves Porret

IPC: G21F5/018 ,  B01L1/02 ,  G21F7/005 ,  G21F7/047

CPC classification number: B01L1/02 ,  G21F7/005 ,  G21F7/047 ,  Y02E50/30

Abstract: A protective device (20) is provided to equip a sterile enclosure (1) configured to be placed in communication with another sterile enclosure (2) so as to allow objects to be transferred from one enclosure to the other. The protective device (20) covers an interface defined between the sterile enclosures (1, 2).

Abstract translation: 提供保护装置（20）以配备被配置成与另一个无菌外壳（2）连通的无菌外壳（1），以允许物体从一个外壳传送到另一个外壳。 保护装置（20）覆盖限定在无菌外壳（1,2）之间的接口。

公开(公告)号：US09040291B2

公开(公告)日：2015-05-26

申请号：US12737332

申请日：2009-06-30

Applicant: Seishi Yamashita

Inventor： Seishi Yamashita

IPC: C12M1/00 ,  C12M3/00 ,  B01L1/02 ,  G01N35/00 ,  G01N35/04

CPC classification number: C12M41/14 ,  B01L1/025 ,  G01N2035/00356 ,  G01N2035/0425

Abstract: Constant-temperature equipment wherein mechanical and electrical structures are eliminated from the inside of a temperature-controlled chamber (15) by using a non-contact magnetic arrangement as a drive transmission for a sample table (5) and a sample table drive mechanism (6), thus reducing failure and enhancing maintainability. In addition, a conveyance mechanism (11) is provided with a pass box adjacent which sliding shielding plates (9) are stacked vertically, and the shielding plates (9) are linked with the conveyance mechanism (11) by an engaging mechanism provided in the conveyance mechanism (11) to allow the plates to be opened and closed by a travel mechanism (12), thus simplifying the structure and minimizing change in atmosphere during conveying. The sample table drive mechanism (6) and the conveyance mechanism (11) can be attached removably to the temperature-controlled chamber (15) to permit sterilization at high temperature.

Abstract translation: 通过使用非接触磁性装置作为样品台（5）和样品台驱动机构（6）的驱动传动装置，其中机械和电气结构从温度控制室（15）的内部消除的恒温设备 ），从而减少故障并提高可维护性。 另外，输送机构11具有与滑动屏蔽板垂直堆叠相邻的通过箱，并且通过设置在所述输送机构中的卡合机构将所述遮蔽板9与所述输送机构11连结。 输送机构（11），通过移动机构（12）使板打开和关闭，从而简化结构并使输送过程中的气氛变化最小化。 样品台驱动机构（6）和输送机构（11）可以可移除地附接到温度控制室（15）以允许在高温下灭菌。

公开(公告)号：US20150099262A1

公开(公告)日：2015-04-09

申请号：US14505028

申请日：2014-10-02

Applicant: Becton, Dickinson and Company

Inventor： Steven MURDOCH ,  Scott HORTON ,  Gil REININ

IPC: G01N15/14 ,  A61L2/20 ,  B01L1/02

CPC classification number: A61L2/20 ,  B01L1/02 ,  B01L2200/082 ,  B01L2300/0681 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2035/00306

Abstract: Flow cytometer systems are provided that mitigate aerosols generated during operation of a flow cytometer. A flow cytometer system can include various combinations of: a flow cytometer instrument base, a flow cytometer, and a biosafety hood (BSH). In some embodiments, a subject flow cytometer system includes a flow cytometer instrument base, a flow cytometer, and a BSH. In some embodiments, a subject flow cytometer system includes a flow cytometer instrument base and a flow cytometer. In some cases, a BSH includes an aerosol management system, which provides a redundant air filtration system. Also provided are components of a flow cytometer system (e.g., a BSH configured to attach to a flow cytometer instrument base, a flow cytometer instrument base configured to attach to a BSH, etc.). Also provided are methods, including methods of performing a flow cytometric procedure using a flow cytometer system; and methods of decontaminating a flow cytometer system.

Abstract translation: 提供了流式细胞仪系统，其减轻在流式细胞仪操作期间产生的气溶胶。 流式细胞仪系统可以包括以下各种组合：流式细胞仪器基座，流式细胞仪和生物安全罩（BSH）。 在一些实施方案中，受试者流式细胞仪系统包括流式细胞仪仪器基座，流式细胞仪和BSH。 在一些实施方案中，受试者流式细胞仪系统包括流式细胞仪仪器基座和流式细胞仪。 在某些情况下，BSH包括气溶胶管理系统，其提供冗余的空气过滤系统。 还提供了流式细胞计数器系统的组件（例如，被配置为附着到流式细胞仪器基座的BSH，被配置为附接到BSH的流式细胞仪器基座等）。 还提供了方法，包括使用流式细胞仪系统进行流式细胞术程序的方法; 以及对流式细胞仪系统进行净化的方法。

公开(公告)号：US20100304658A1

公开(公告)日：2010-12-02

申请号：US12297054

申请日：2007-04-16

Applicant: Vladimir Grcevic

Inventor： Vladimir Grcevic

IPC: B01L1/02

CPC classification number: E04B1/3444 ,  B60P3/005 ,  B60P3/14 ,  B60P3/34 ,  E04H1/1277 ,  E04H3/08

Abstract: This invention relates to a mobile laboratory for analysis of pathogenic agents. According to the invention, the laboratory (1) consists of a transportable mobile container defining a basic chamber (10), the space inside said chamber being isolated from the outside by means of a sealed box (5) inserted in said room, said box comprising a sealed zone for analysis of pathogenic agents (50d, 500d) fitted with a pressure device that maintains a negative pressure inside said zone relative to its external environment, characterised in that the sealed box (5) includes a first protective equipment airlock (500a), - a second sealed airlock (500b) communicating between said sealed zone for the analysis of pathogenic agents and said first airlock, a third sealed airlock (500c) communicating between said sealed zone for the analysis of pathogenic agents and said first airlock, wherein the zone for analysing pathogenic agents (500d) can only be entered through said second airlock.

Abstract translation: 本发明涉及用于分析病原体的移动实验室。 根据本发明，实验室（1）由限定基本室（10）的可移动移动容器组成，所述室内的空间借助于插入所述房间的密封盒（5）与外部隔离，所述盒 包括用于分析装有压力装置的致病剂（50d，500d）的密封区，所述压力装置相对于其外部环境保持在所述区域内的负压，其特征在于，所述密封箱（5）包括第一保护装置气锁（500a ）， - 在用于分析病原体和所述第一气闸的所述密封区域之间连通的第二密封气闸（500b），在所述密封区域之间连通用于分析病原体和所述第一气锁的第三密封气锁（500c），其中 用于分析病原体（500d）的区域只能通过所述第二气闸进入。

公开(公告)号：US20070189934A1

公开(公告)日：2007-08-16

申请号：US11567456

申请日：2006-12-06

Applicant: Barry King ,  Eric Hoart

Inventor： Barry King ,  Eric Hoart

IPC: B01L1/02

CPC classification number: C40B60/14 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00454 ,  B01J2219/00459 ,  B01J2219/00466 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00695 ,  B01J2219/00722 ,  B01J2219/00725 ,  C40B50/14 ,  G01N35/1002

Abstract: A solid phase synthesis system including one or more reaction vessels, one or more structural unit chemical dispensing units, one or more synthesis chemical dispensing units, and a controller is provided. The arrangement of the reaction vessels, dispensing units and corresponding fluid interconnections restricts cross-contamination within the system. The controller facilitates automated or semi-automated production of various organic compounds. Associated software including varying command structures may be provided to facilitate ease in programming and automating of the synthesis system.

Abstract translation: 提供了包括一个或多个反应容器，一个或多个结构单元化学分配单元，一个或多个合成化学品分配单元和控制器的固相合成系统。 反应容器，分配单元和相应的流体互连的布置限制了系统内的交叉污染。 控制器便于自动化或半自动化生产各种有机化合物。 可以提供包括变化的命令结构的相关软件，以便于编程和自动化合成系统的容易性。

公开(公告)号：US20050079602A1

公开(公告)日：2005-04-14

申请号：US10958543

申请日：2004-10-06

Applicant: Laurent Mimaud ,  Veronique Ollivier

Inventor： Laurent Mimaud ,  Veronique Ollivier

IPC: C12M1/38 ,  B01L1/00 ,  B01L1/02 ,  B01L99/00 ,  C12M1/00 ,  F25D23/02 ,  C12M1/34

CPC classification number: C12M41/14 ,  B01L1/02 ,  B01L9/52 ,  B01L13/02

Abstract: This enclosure comprises a body which itself comprises: a structure which internally delimits a processing space which opens at the outer side of the structure by way of an opening, at least one framework element which is fixed in a removable manner to the structure in order to delimit, in the opening (13), at least two zones for access to separate regions of the processing space. At least two gates are mounted so as to be movable on the structure in order selectively to close and open the access zones. Application, for example, to CO2 incubators.

Abstract translation: 该外壳包括本体，该主体本身包括：内部限定通过开口在该结构的外侧开口的处理空间的结构，至少一个框架元件，该框架元件以可拆卸的方式固定到该结构，以便 在开口（13）中限定用于访问处理空间的单独区域的至少两个区域。 安装至少两个门，以便能够在结构上移动以便有选择地关闭和打开接入区。 例如，应用于二氧化碳培养箱。

公开(公告)号：US6051439A

公开(公告)日：2000-04-18

申请号：US947476

申请日：1997-10-10

Applicant: Valery V. Antonenko ,  Nicolay V. Kulikov

Inventor： Valery V. Antonenko ,  Nicolay V. Kulikov

IPC: B01J19/00 ,  B01L3/00 ,  C40B40/06 ,  C40B40/10 ,  C40B50/14 ,  C40B60/14 ,  B01L1/02 ,  B01L7/00

CPC classification number: B01L3/5025 ,  B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00313 ,  B01J2219/00315 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/00416 ,  B01J2219/00418 ,  B01J2219/00423 ,  B01J2219/00454 ,  B01J2219/005 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  C40B40/06 ,  C40B40/10 ,  C40B50/14 ,  C40B60/14 ,  Y10T436/25 ,  Y10T436/255

Abstract: The invention provides a method for synthesizing various chemicals onto solid supports, cleaving the synthesized compounds and preparing samples for analysis. In one exemplary embodiment, the invention provides a device comprising a housing which defines an enclosure. A plate having a plurality of wells is received into the enclosure. Each of the wells has a bottom end and at least some of the wells have a hole in the bottom end. A pressure source is in fluid communication with the holes in the bottom ends of the wells. In this manner, a fluid may be maintained within the wells by application of pressure from the pressure source.

Abstract translation: 本发明提供了一种在固体支持物上合成各种化学物质的方法，裂解合成的化合物并制备用于分析的样品。 在一个示例性实施例中，本发明提供了一种包括限定外壳的壳体的装置。 具有多个孔的板被接收到外壳中。 每个井具有底端，并且至少一些井在底端具有孔。 压力源与井底端的孔流体连通。 以这种方式，可以通过施加来自压力源的压力将流体保持在孔内。

公开(公告)号：US5611207A

公开(公告)日：1997-03-18

申请号：US496428

申请日：1995-06-29

Applicant: John Hess

Inventor： John Hess

IPC: B01L1/02 ,  F17C13/00 ,  F25D19/00 ,  G01N1/42 ,  F25B19/00

CPC classification number: F17C13/006 ,  B01L1/02 ,  F25D19/006 ,  F17C2203/0391 ,  F17C2205/0323 ,  F17C2223/0161 ,  F17C2227/0337 ,  G01N1/42

Abstract: A cryogenically efficient interface which enables the quick loading of completely configured Independent Measurement Inserts in a direction perpendicular to the temperature gradient of a cryogenic cooling source. An air lock and precooling means provide a method for loading independent measurement inserts directly into the cryostat vacuum without applying an undue initial or steady thermal load on the cooling source. A heat switch provides means for establishing variable thermal contact between the contoured independent measurement inserts and the cold stage of a cryogenic cooling source. There is a free selection in the cryogenic cooling source which may be used and also in the types of measurements which may be configured and loaded by the means of appropriately configured idependent measurement inserts. Loading of measurement inserts may be carried out in any direction. The experimental flexibility gained in the use of my invention is a benefit to scientists and engineers wishing to conveniently perform a diversity of different measurements at cryogenic temperatures.

Abstract translation: 一种低温有效的界面，使得能够在垂直于低温冷却源的温度梯度的方向快速加载完全配置的独立测量插入件。 空气锁和预冷装置提供了将独立的测量插入件直接装载到低温恒温器真空中而不在冷却源上施加不适当的初始或稳定的热负荷的方法。 热开关提供用于在轮廓独立测量插入件和低温冷却源的冷段之间建立可变热接触的装置。 可以使用低温冷却源中的可选择，也可以通过适当配置的独立测量插入件的装置来配置和加载测量类型。 测量插入件的装载可以在任何方向进行。 在使用我的发明时获得的实验灵活性对于希望在低温下方便地执行不同测量的科学家和工程师是有利的。

公开(公告)号：US5545841A

公开(公告)日：1996-08-13

申请号：US314024

申请日：1994-09-28

Applicant: William W. Wilfinger ,  Bruce Kendall

Inventor： William W. Wilfinger ,  Bruce Kendall

IPC: B01L1/02 ,  B64G1/22 ,  H05K5/06

CPC classification number: B01L1/02 ,  B64G1/22

Abstract: A seamless, light weight container that provides two levels of liquid and gaseous containment. The container has removable covers that have a double seal which allows confirmation of seal integrity prior to shipment by applying a vacuum or pressure to the internal space between the inner and outer seals. This close-out vacuum or pressure test can be completed within minutes and it provides certification that the container seals meet design criteria for quick turn-around in spacecraft environments.

Abstract translation: 一个无缝，重量轻的容器，提供两级液体和气体收容。 容器具有可拆卸的盖，其具有双重密封，其允许通过对内密封件和外密封件之间的内部空间施加真空或压力来确认在出货之前的密封件完整性。 这种关闭的真空或压力测试可以在几分钟内完成，并提供容器密封件符合设计标准的认证，以便在航天器环境中快速翻转。