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公开(公告)号:US12128415B2
公开(公告)日:2024-10-29
申请号:US17195206
申请日:2021-03-08
Applicant: Pattern Bioscience, Inc.
Inventor: Ross Johnson , Jonathan Isom , David Bussian , Nicolas Arab
CPC classification number: B01L9/527 , B01L1/02 , B01L3/502715 , B01L3/50273 , B01L3/502784 , G01N21/31 , B01L2200/0642 , B01L2200/0647 , B01L2300/0663 , B01L2400/049
Abstract: An apparatus for loading and imaging a microfluidic chip can comprise a housing having walls that define a vacuum chamber and a first receptacle disposed within the vacuum chamber, the first receptacle defining a space for receiving one or more microfluidic chips. The apparatus can also include a negative pressure source, a light source, and an optical sensor coupled to the housing. The negative pressure source can be configured to reduce pressure within the vacuum chamber, the light source can be positioned to illuminate at least a portion of the space for receiving the chip(s), and the optical sensor can be positioned to capture an image of at least a portion of the space for receiving the chip(s).
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公开(公告)号:US12105106B2
公开(公告)日:2024-10-01
申请号:US17294352
申请日:2018-11-16
Applicant: AIXINNO LIMITED
CPC classification number: G01N35/025 , B01L1/02 , C12M23/44 , B01L2200/028 , B01L2200/141 , B01L2300/0829 , C12M23/48 , G01N2035/00326 , G01N2035/0418 , G01N2035/0465
Abstract: A process module for a biology laboratory system includes a housing, a working deck located within the housing, having working deck plate slots for receiving cell culture plates, a liquid handling robot comprising at least one pipette for aspirating a liquid medium, and a first transfer interface in communication with a first storage module for storing cell culture plates. The working deck is movable to a plurality of working positions. In one of the positions, the cell culture plate is located under an operating point of the liquid handling robot. In another of the positions, the cell culture plate is in alignment with the first transfer interface for transfer of the cell culture plate between an outside of the housing and the working deck plate slot. The first transfer interface or a second interface can be brought in communication with a second storage module for storing lab-ware or liquid material.
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公开(公告)号:US20240189809A1
公开(公告)日:2024-06-13
申请号:US17615969
申请日:2021-06-15
Inventor: Takeshi MATSUMURA , Takeshi KANEKO
CPC classification number: B01L1/02 , B01L1/50 , B01L2200/082 , B01L2200/085
Abstract: A safety cabinet has an opening portion in the front surface of a work room and a front shutter and supplies clean air to the work room from above. A side slit is provided in the side surface of the work room, air from the provided side slit joins an air flow path suctioned from a front grille of a workbench forming the bottom surface of the work room, and the turbulence of an airstream can be prevented even when a device is installed in the work room.
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公开(公告)号:US11874288B1
公开(公告)日:2024-01-16
申请号:US16247925
申请日:2019-01-15
Applicant: Redshift Bioanalytics, Inc.
Inventor: Charles McAlister Marshall , Richard C. Sharp , Frederick Milton Blodgett, Jr. , Vlorent Morina , Jerry E. Hurst, Jr.
CPC classification number: G01N35/00732 , B01L1/02 , B01L3/50851 , B01L3/50853 , B01L3/565 , B01L5/00 , B01L7/54 , B01L2200/146 , B01L2300/048 , B01L2300/0663 , B01L2300/0829 , B01L2300/0861 , B01L2300/14 , B01L2300/16 , B01L2300/1805 , B01L2300/1833
Abstract: A well plate includes a frame section that defines a plane, and a plurality of well structures. Each well structure extends in a direction away from the plane defined by the frame section, and each well structure defines a well for holding a fluid. The well plate further includes an artifact connected to at least one well structure. The artifact uniquely identifies a type of the well plate among other types of well plates. Along these lines, a result of a well plate type identification operation, which indicates whether the well plate includes the artifact, may determine whether a predefined pressure is applied to the well plate to facilitate fluid sampling in response to the result, whether fluid level sensing can be performed to gauge amounts of fluids drawn from the wells and/or identify how much fluid is left in the wells, etc.
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公开(公告)号:US20230415142A1
公开(公告)日:2023-12-28
申请号:US18038397
申请日:2021-11-29
Applicant: CYTENA BIOPROCESS SOLUTIONS CO., LTD
Inventor: Cheng-Han TSAI , Da-Han KUAN , Cheng-Yu JIANG
CPC classification number: B01L1/02 , B01L3/5027 , C12M29/14 , G01N21/80 , B01L2200/028 , B01L2300/0681 , B01L2400/0487 , B01L2400/06
Abstract: The invention relates to a control unit for a fluid control device wherein the control unit comprises a pressure unit for providing positive and/or negative pressure, at least one first control unit outlet being fluidically connectable to a processing device comprising at least one receptacle for receiving a fluid sample, at least one second control unit outlet being fluidically connectable to a treatment device having a chamber for receiving the processing device, and a connection unit by means of which the pressure unit is fluidically connectable or connected with the first control unit outlet and/or with the second control unit outlet wherein the control unit is adapted to control the processing of the fluid sample in the processing device by applying a positive or negative pressure provided by the pressure unit to the first control unit outlet by means of the connection unit and to control a physical state in the chamber of the treatment device.
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公开(公告)号:US11796552B2
公开(公告)日:2023-10-24
申请号:US17448011
申请日:2021-09-17
Applicant: Genesis Technologies Limited
Inventor: Jan-Eric Ahlfors
CPC classification number: G01N35/1002 , B01L1/02 , B01L1/04 , G01N35/0099 , B01L2300/06 , B01L2300/14 , G01N2035/00277 , G01N2035/00306 , G01N2035/1051
Abstract: A system for automated processing of a plurality of batches, each batch being derived from one biological sample, the system comprising an enclosure which can be closed and sterilized, each batch of the plurality of batches comprising one or more cell processing container; a plurality of reagent containers for holding reagents within the enclosure; at least one reagent dispenser within the enclosure for dispensing reagents during said automated processing; a quality control system within the enclosure for analyzing at least one characteristic of a batch during said automated processing; a harvester within the enclosure for harvesting batches; a robotic system within the enclosure, configured for transporting cell processing containers, decapping or otherwise opening cell processing containers, pipetting reagents or liquids from cell processing containers, and aspirating liquids from cell processing containers, during said automated processing; a tracker for electronically tracking the plurality of batches after its introduction to the enclosure; and a control unit (CU) communicatively coupled to the at least one reagent dispenser, the quality control system, the harvester, the robotic system and the tracker for controlling said automatic processing of said batches.
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公开(公告)号:US11719713B2
公开(公告)日:2023-08-08
申请号:US16349994
申请日:2017-11-17
Applicant: MonTech System Solutions GmbH
Inventor: Ralf Bäuerlein
CPC classification number: G01N35/0099 , B01L1/02 , B01L9/00 , B25J15/0066 , B25J15/0071 , B25J15/0206 , B25J15/0616 , G01N33/442 , B01L2200/087 , B01L2300/10
Abstract: A skewer-type gripper for one-sidedly receiving a test sample positioned in a defined manner and still compressed by plungers in a punching device and consisting of viscoelastic materials with an upper side and an edge area. The gripper has a base and skewer-type means arranged in a plane therein, which can pierce into the edge area of the still compressed test sample parallel to the upper side. The skewer-type means are configured in such a way that the test sample can be received and held in a torque-proof manner by the skewer-type means. The gripper is configured and set up for horizontally receiving the test sample from a punching device, and the gripper or skewer-type means can be exposed to a feed force for this purpose.
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公开(公告)号:US20180326665A1
公开(公告)日:2018-11-15
申请号:US15755767
申请日:2016-08-31
Applicant: Erik Gatenholm , Ivan Tournier , Paul Gatenholm , Cellink AB
Inventor: Erik Gatenholm , Ivan Tournier , Paul Gatenholm
IPC: B29C64/364 , C12M3/00 , B33Y30/00 , B29C64/264 , B29C64/245 , B33Y50/02 , B29C64/393 , B29C64/25
CPC classification number: B29C64/364 , B01L1/02 , B01L3/0241 , B01L2200/0636 , B01L2300/0681 , B29C64/245 , B29C64/25 , B29C64/264 , B29C64/393 , B29L2031/40 , B33Y30/00 , B33Y40/00 , B33Y50/02 , B33Y70/00 , B33Y80/00 , C12M21/08 , F24F3/161 , F24F13/28 , F24F2011/0004
Abstract: Clean chamber technology for 3D printers and bioprinters is described. An airtight chamber or enclosure is provided so that positive pressure can be created inside the chamber. Unfiltered air is sucked in from outside into the chamber through a high efficiency filter such as a HEPA filter, using an electrically powered fan or blower, filtering out at least about 99% of particles and contaminants. The filtered air is then pushed into a 3D printing area inside the chamber and out through vents within the frame of the chamber. The technology provides a clean environment for 3D bioprinting of human tissue models and organs and 3D cell culturing without requiring clean room facilities.
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公开(公告)号:US20180229888A1
公开(公告)日:2018-08-16
申请号:US15952106
申请日:2018-04-12
Applicant: Ideal Vacuum Products LLC
Inventor: Tony C Smith , Richard D Holets
IPC: B65D21/02
CPC classification number: B65D21/0201 , B01L1/02 , B01L2200/028 , B01L2200/0689 , B01L2400/049
Abstract: A modular vacuum chamber system provides for tapered surfaces and resilient sealing members, wherein the tapered surfaces are protected from undesired contact with work surfaces, and provide for vacuum-tight engagement of various modules. Modules can include chamber modules, defining shapes for a resultant vacuum chamber. Modules can comprise connecting modules, configured to sealingly engage two chamber modules and form a larger vacuum chamber than either module alone. Modules can comprise wall plate modules, configured to sealingly engage a chamber module and form a surface of a vacuum chamber. Wall plate modules can comprise solid plates, optically transparent plates, and plates accommodating ports for communication between the vacuum chamber and the environment outside the vacuum chamber.
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公开(公告)号:US20180078930A1
公开(公告)日:2018-03-22
申请号:US15554248
申请日:2016-02-29
Applicant: Delaware Capital Formation, Inc.
Inventor: Steven Bruce Williams, II , Isaac M. Giesen
IPC: B01L1/02
CPC classification number: B01L1/02 , B01L2200/023 , B01L2200/141 , B01L2300/043
Abstract: The current technology relates to a portion of a transfer port having a port ring configured for placement in a barrier wall. The port ring has a first side and a second side and defines a port opening extending from the first side to the second side. A port door is pivotably coupled to the second side and is configured to selectively and sealably obstruct the port opening. The port ring defines a sealing surface on the first side of the port ring, concentric to the port opening that is configured to receive a gasketing material. The port ring defines an interface insert receptacle having a portion of an annular surface concentric to the sealing surface and an inner cylindrical face extending between the first side and the annular surface. The port ring is configured define a fastening structure that is configured to releasably fasten to an interface insert.
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