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公开(公告)号：US20080182263A1
公开(公告)日：2008-07-31
申请号：US12022079
申请日：2008-01-29
Applicant: Stephen J. Gunstream
Inventor： Stephen J. Gunstream
CPC classification number: C12Q1/6851 , G01N21/274 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2021/6441 , G01N2201/12 , G01N2201/12746 , G16B30/00 , C12Q2545/113 , C12Q2545/101
Abstract: The present teachings relate to a method of generating calibration information during a real-time polymerase chain reaction (RT-PCR) or other amplification reaction. A sample well plate or other support can contain one or more dyes or other reference materials that are subjected to the same RT-PCR thermal cycles or other conditions used to conduct amplification or other reactions on a biological sample. A set of maxima values and a set of minimum values, and/or other calibration information useful for adjusting emission data for sample dyes can be recorded, for example, for 10 cycles, 20 cycles, or each cycle of a complete RT-PCR run. Such testing of dye response under realistic operating conditions can enable more accurate characterization of plate, dye, filter, or instrument response and therefore more accurate calibration corrections and other and/or adjustments.
Abstract translation: 本教导涉及在实时聚合酶链反应（RT-PCR）或其他扩增反应期间产生校准信息的方法。 样品孔板或其它载体可以含有一种或多种经受相同RT-PCR热循环或用于在生物样品上进行扩增或其他反应的其他条件的染料或其它参考物质。 可以记录一组最大值和一组最小值，和/或可用于调整样品染料的发射数据的其他校准信息，例如10个循环，20个循环或完整RT-PCR运行的每个循环 。 在真实的操作条件下对染料响应的这种测试可以实现板，染料，过滤器或仪器响应的更精确的表征，因此可以进行更精确的校准校正和其他和/或调整。
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公开(公告)号：US20080178653A1
公开(公告)日：2008-07-31
申请号：US12022094
申请日：2008-01-29
Applicant: Stephen J. Gunstream
Inventor： Stephen J. Gunstream
IPC: G01N37/00
CPC classification number: C12Q1/6851 , G01N21/274 , G01N21/6428 , G01N21/6486 , G01N2021/6439 , G01N2021/6441 , G01N2201/12 , G01N2201/12746 , G16B30/00 , C12Q2545/113 , C12Q2545/101
Abstract: Systems and methods are provided for calibrating emission data or other information signals collected during a polymerase chain reaction (PCR), amplification reaction, assay, process, or other reaction. Calibration of multiple detectable materials can be achieved during a single cycle or run, or during a plurality of runs of the reaction. A reading from every well, container, or other support region of a sample support does not have to be taken. Interpolation can be used to determine values for emission data or other information signals that were not taken, or are unknown, using detected emission data, or other detected information signals. By calibrating the detected emission data and the interpolated data, a more accurate reading of emission data or information signal can be obtained.
Abstract translation: 提供了系统和方法，用于校准在聚合酶链式反应（PCR），扩增反应，测定，过程或其他反应期间收集的排放数据或其他信息信号。 可以在单个循环或运行期间或在多次反应运行期间实现多个可检测材料的校准。 来自样品支架的每个孔，容器或其他支撑区域的读数不必采取。 内插可用于确定未使用或未知的使用检测到的发射数据或其他检测到的信息信号的发射数据或其他信息信号的值。 通过校准检测到的发射数据和内插数据，可以获得更准确的发射数据或信息信号读数。
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53.发明授权Methods for controlling one or more parameters of a flow cytometer type measurement system 有权用于控制流式细胞仪型测量系统的一个或多个参数的方法公开(公告)号：US07318336B2
公开(公告)日：2008-01-15
申请号：US10918647
申请日：2004-08-13
Applicant: Wayne D. Roth , Douglas E. Moore
Inventor： Wayne D. Roth , Douglas E. Moore
IPC: G01N21/00
CPC classification number: G01N15/1404 , G01N15/1012 , G01N21/645 , G01N2015/1415 , G01N2015/1477 , G01N2201/12746
Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.
Abstract translation: 提供了用于控制流式细胞仪型测量系统的一个或多个参数的各种方法。 一个实施例包括在样品微球的测量期间监测测量系统的参数。 该方法还包括基于监视实时更改参数。 另一种方法包括监测靠近测量系统的温度。 一种这样的方法包括使用经验导出的数据来响应于温度来改变雪崩光电二极管的偏置电压。 不同的这种方法包括使用特性曲线响应于温度改变光电倍增管的输出信号。 一些方法包括监测将流过流式细胞仪类型测量系统的流体样品微球的设置温度。 该方法还包括从该温度下的流体的粘度确定测量系统中的样品微球的速度。
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公开(公告)号：US11726033B1
公开(公告)日：2023-08-15
申请号：US17682243
申请日：2022-02-28
Applicant: Saudi Arabian Oil Company
Inventor： Mohammad Alharthy , Osama Alzahrani , Nada Alghamdi , NagoorPitchal MeeranPillai , Ali Almuhaimeed
CPC classification number: G01N21/33 , G01N1/4077 , G01N33/1833 , G01N2001/4083 , G01N2201/127 , G01N2201/12746
Abstract: A method for quantifying a crude oil in water is provided. The method includes selecting an ultraviolet/visible (UV/Vis) wavelength to perform a measurement, preparing calibration solutions in xylene, and preparing a calibration curve from the calibration solutions. A sample is prepared including extracting the crude oil from the water in a two-phase separation with xylene. An absorbance of the sample in the xylene is measured at the UV/Vis wavelength. A concentration of the crude oil in the water is calculated from the absorbance.
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公开(公告)号：US20230204499A1
公开(公告)日：2023-06-29
申请号：US18090609
申请日：2022-12-29
Applicant: Chengdu Sea Pioneers Technology Co.,Ltd.
CPC classification number: G01N21/31 , G01N21/85 , G01N2201/12746
Abstract: Disclosed are a method and a device for measuring a sand content in a miscible phase fluid, the method comprising: flowing of the miscible phase fluid out of an oil and gas well through a pipeline, the miscible phase fluid of the wellhead of the oil and gas well including at least two fluid media; carrying out a measurement with a light quantum of four levels on the miscible phase fluid by a phase separator installed on the pipeline, such that a linear mass of each fluid medium is obtained; calculating a sand content in mass fraction based on the linear mass of all the fluid media, when the fluid media in the miscible phase fluid includes a solid phase sand.
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Patent Agency Ranking
公开(公告)号：US20190079024A1
公开(公告)日：2019-03-14
申请号：US16186906
申请日：2018-11-12
Applicant: GOJO Industries, Inc.
Inventor： Mark W. Moore
CPC classification number: G01N21/94 , G01N21/00 , G01N21/63 , G01N21/64 , G01N21/84 , G01N21/88 , G01N21/8806 , G01N2201/127 , G01N2201/12746
Abstract: One or more techniques and/or systems are provided for waste object detection. For example, a waste alert component is configured to emit ultraviolet light towards a waste detection zone, such as a bathroom floor or countertop. If a waste object, such as a paper towel or other object with a fluoresce property, exists within the waste detection zone, then the waste alert component may detect an increase in light due to the waste object fluorescing visible light in response to the ultraviolet light. If the increase in light intensity exceeds a detection threshold, then the waste alert component may provide a waste detection alert that the waste object exists within the waste detection zone (e.g., a message may be sent to a housekeeper that paper towel waste in on the bathroom countertop).
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57.发明申请公开(公告)号：US20180088034A1
公开(公告)日：2018-03-29
申请号：US15708610
申请日：2017-09-19
Applicant: Seiko Epson Corporation
Inventor： Tsukasa EGUCHI , Hideto ISHIGURO , Hikaru KURASAWA
IPC: G01N21/27 , G01N21/359
CPC classification number: G01N21/274 , G01N21/359 , G01N2201/12746 , G01N2201/1293
Abstract: A calibration data acquisition unit uses an equation X=YW in which an optical spectrum matrix X is the same as a product between a component natural spectrum matrix Y and a component amount matrix X, performs independent component analysis in which column vectors of the component amount matrix W are treated as independent components so as to determine the component natural spectrum matrix Y, and employs row vectors of a general inverse matrix Y† of the component natural spectrum matrix Y as component calibration spectra corresponding to a plurality of components. A calibration curve is created by using a target component calibration spectrum corresponding to a target component.
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58.发明申请公开(公告)号：US20180088032A1
公开(公告)日：2018-03-29
申请号：US15708516
申请日：2017-09-19
Applicant: Seiko Epson Corporation
Inventor： Hikaru KURASAWA
CPC classification number: G01N21/274 , G01N21/35 , G01N2201/12746 , G01N2201/1293
Abstract: A calibration data acquisition unit (a) acquires Q optical spectra and S evaluation spectra, (b) extracts R subsets from a set of the Q optical spectra, (c) performs independent component analysis in which component amounts in each sample treated as independent components on each of R subsets so as to acquire R×N component calibration spectra, (d) obtains an inner product value between the R×N component calibration spectrum and an evaluation spectrum, (e) selects a component calibration spectrum for which a correlation degree between a component amount for the target component and the inner product value is the maximum as the target component calibration spectrum from among the R×N component calibration spectra, and (f) creates a calibration curve by using the target component calibration spectrum.
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59.发明申请公开(公告)号：US20180067054A1
公开(公告)日：2018-03-08
申请号：US15698007
申请日：2017-09-07
Applicant: Radhika Suresh , Sankaran Murugesan , Valery N. Khabashesku , Darryl Ventura
Inventor： Radhika Suresh , Sankaran Murugesan , Valery N. Khabashesku , Darryl Ventura
IPC: G01N21/65
CPC classification number: G01N21/658 , G01N2201/127 , G01N2201/12746
Abstract: A method of analyzing a selected refinery chemical at a low concentration comprises contacting a sample with functionalized metallic nanoparticles that contain metallic nanoparticles functionalized with a functional group comprising a cyano group, a thiol group, a carboxyl group, an amino group, a boronic acid group, an aza group, an ether group, a hydroxyl group, or a combination comprising at least one of the foregoing; radiating the sample contacted with the functionalized metallic nanoparticles with electromagnetic radiation at a selected energy level; measuring a Raman spectrum emitted from the sample; and determining the presence or a concentration of a selected refinery chemical in the sample from the Raman spectrum.
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公开(公告)号：US09874515B2
公开(公告)日：2018-01-23
申请号：US14895946
申请日：2013-06-04
Applicant: Foss Analytical
Inventor： Per Waaben Hansen
CPC classification number: G01N21/35 , G01J3/0291 , G01J3/42 , G01J3/45 , G01N21/274 , G01N2021/3595 , G01N2201/061 , G01N2201/12746
Abstract: A method of determining a pathlength deviation of a sample (610), the method comprising: exposing the sample (610) to electromagnetic radiation at a plurality of wavenumbers, determining electromagnetic absorption in the sample (610) at the plurality of wavenumbers, determining a first wavenumber associated with a first absorption level of an absorption band and a second wavenumber associated with a second absorption level of the absorption band, wherein the second wavenumber is different from the first wavenumber, determining a difference between the first wavenumber and the second wavenumber, and determining the pathlength deviation based on the difference.
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