公开(公告)号：US09677997B2

公开(公告)日：2017-06-13

申请号：US15095724

申请日：2016-04-11

Applicant: DEKA Products Limited Partnership

Inventor： Jacob W. Scarpaci ,  Jason M. Sachs ,  Simon C. Helmore

IPC: G01J4/04 ,  G01N21/21 ,  G01N21/90 ,  A61M1/14

CPC classification number: G01N21/21 ,  A61M1/14 ,  G01J4/04 ,  G01N21/90 ,  G01N2201/0612 ,  G01N2201/0683

Abstract: Methods and apparatus for concentration determination using polarized light. The apparatus includes a first polarized light source having a first light source polarization axis and a second polarized light source having a second light source polarization axis generally perpendicular to the first light source polarization axis. Also, a first polarized light receiver having a first polarized light receiver polarization axis and configured to measure an intensity of light transmitted from the first light receiver polarizer and a second polarized light receiver having a second polarized light receiver polarization axis substantially perpendicular to the first light receiver polarization axis and configured to measure an intensity of light transmitted from the second light receiver polarizer, wherein the first and second light receiver polarization axes are generally +/−45 degrees relative to the first and second light source polarization axes.

公开(公告)号：US20170146513A1

公开(公告)日：2017-05-25

申请号：US15425729

申请日：2017-02-06

Applicant: Case Western Reserve University

Inventor： Brian T. Grimberg ,  Robert Deissler ,  William Condit ,  Robert Brown ,  Jason Jones ,  Richard Bihary

IPC: G01N33/49 ,  G01N21/59 ,  G01N27/72 ,  G01N21/21

CPC classification number: G01N33/48 ,  G01N1/28 ,  G01N21/21 ,  G01N21/59 ,  G01N33/49 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position.

公开(公告)号：US20170097601A1

公开(公告)日：2017-04-06

申请号：US15373112

申请日：2016-12-08

Applicant: Noriaki TAKENAGA ,  Tohru MATSUMOTO ,  Tetsuya OFUCHI ,  Takayuki NISHIMURA ,  Yukifumi KOBAYASHI ,  Hideyo MAKINO ,  Satoshi NAKAYAMA

Inventor： Noriaki TAKENAGA ,  Tohru MATSUMOTO ,  Tetsuya OFUCHI ,  Takayuki NISHIMURA ,  Yukifumi KOBAYASHI ,  Hideyo MAKINO ,  Satoshi NAKAYAMA

IPC: G03G15/00

CPC classification number: G03G15/5062 ,  G01B5/0023 ,  G01B5/24 ,  G01N21/21 ,  G01N21/474 ,  G01N21/55 ,  G01N21/59 ,  G01N2021/556 ,  G01N2021/558 ,  G01N2201/0612 ,  G01N2201/0683 ,  G03G15/5029 ,  G03G2215/00738 ,  G03G2215/00751

Abstract: A sheet discriminator, which can be included in an image forming apparatus, includes an optical information detector, a sheet distinguisher, and a sheet thickness detector. The optical information detector includes a light emitter to emit light to a recording medium and a light receiver to receive the light and detects information of the recording medium. The sheet distinguisher distinguishes a type of the recording medium based on the information detected by the optical information detector. The sheet thickness detector includes a displacement gauge to sandwich the recording medium with an opposing member disposed facing the displacement gauge and to move from an initial position thereof and a displacement detector to detect an amount of displacement of the displacement gauge. The sheet thickness detector detects a thickness of the recording medium based on detection results obtained by the displacement detector.

公开(公告)号：US20170074796A1

公开(公告)日：2017-03-16

申请号：US15311311

申请日：2015-05-08

Applicant: TOHOKU UNIVERSITY ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Akihide HIBARA ,  Manabu TOKESHI ,  Osamu WAKAO

IPC: G01N21/64

CPC classification number: G01N21/6445 ,  G01J3/0224 ,  G01J4/00 ,  G01N21/64 ,  G01N21/6456 ,  G01N33/542 ,  G01N2201/0675 ,  G01N2201/0683 ,  G02F1/13

Abstract: An excitation light source emits excitation light to a target sample. An image sensor includes pixels arranged one-dimensionally or two-dimensionally, and receives measurement light from the sample according to the excitation light. A polarization selector arranged between the sample and image sensor includes pixels arranged one-dimensionally or two-dimensionally. Each pixel receives a corresponding portion of the measurement light, selects light having a polarization direction that corresponds to a driving signal applied to the pixels, and supplies this light to the image sensor. A measurement control unit supplies the cyclic driving signal having a first period T1 and acquires data I1, I2, I3, and I4 from each pixel of the image sensor for each exposure time segment T2=T1/4 obtained by dividing the first period T1 by 4.

Abstract translation: 激发光源向目标样品发射激发光。 图像传感器包括一维或二维排列的像素，并且根据激发光接收来自样品的测量光。 布置在样本和图像传感器之间的偏振选择器包括一维或二维布置的像素。 每个像素接收测量光的对应部分，选择具有与施加到像素的驱动信号相对应的偏振方向的光，并将该光提供给图像传感器。 测量控制单元提供具有第一周期T1的循环驱动信号，并且通过将每个曝光时间段T2 = T1 / 4从图像传感器的每个像素获取数据I1，I2，I3和I4， 4。

公开(公告)号：US09575052B2

公开(公告)日：2017-02-21

申请号：US14766523

申请日：2014-02-10

Applicant: Case Western Reserve University

Inventor： Brian T. Grimberg ,  Robert Deissler ,  William Condit ,  Robert Brown ,  Jason Jones ,  Richard Bihary

IPC: G01N33/48 ,  G01N33/49 ,  G01N21/21 ,  G01N1/28 ,  G01N21/59

CPC classification number: G01N33/48 ,  G01N1/28 ,  G01N21/21 ,  G01N21/59 ,  G01N33/49 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position.

Abstract translation: 提供一种诊断装置，其包括用于将光束通过血液样本传输到光检测器的光源和永磁体，其中永磁体和血液样本中的一个可自动地相对于另一个在“HIGH” 磁状态位置和“低”磁状态位置，使得基本上高的磁场被施加到血液样本，导致血样中的任何血红素趋向于垂直取向于大体上的磁场，并抑制或增强光 基于其极化，并且将零到接近零的磁场施加到血液样品，导致血液样品中任何血红素的随机化，并且基线量的光通过血液样本在“低”磁性 状态。

公开(公告)号：US20170038290A1

公开(公告)日：2017-02-09

申请号：US15302949

申请日：2015-02-19

Applicant: MITSUBISHI ELECTRIC CORPORATION

Inventor： Kenya NAKAI ,  Nobuo TAKESHITA

IPC: G01N15/14 ,  G01N21/49 ,  G01N15/06

CPC classification number: G01N15/1434 ,  G01N15/0211 ,  G01N15/06 ,  G01N21/49 ,  G01N21/53 ,  G01N2015/0046 ,  G01N2015/0693 ,  G01N2015/1454 ,  G01N2201/06113 ,  G01N2201/0683 ,  G01S7/4916 ,  G01S7/499 ,  G01S17/95 ,  H01S5/0028 ,  H01S5/0427 ,  H01S5/0617 ,  H01S5/06832

Abstract: A floating particle detection device 1 is capable of accurately identifying the type of a floating particle while achieving simplification of a configuration of the device, the device includes: a laser light irradiator (10) that includes a laser light emitting element (11) and a back-monitor-use light receiving element (12); a scattered light receiver (20) that selectively receives light of a predetermined polarization component among scattered light generated when a floating particle (50) is irradiated and that generates a second detection signal; and an identification processor (30) that identifies the type of the floating particle on the basis of a first detection signal and the second detection signal. Incident light entering the back-monitor-use light receiving element (12) includes: a back-monitor-use laser beam (L0); and backscattered light (Lbs) travelling toward the laser light irradiator (10) among the scattered light (Ls).

Abstract translation: 浮动粒子检测装置1能够在实现装置的构造简化的同时精确地识别浮动粒子的类型，该装置包括：激光照射器（10），其包括激光发射元件（11）和 背部监视器使用的光接收元件（12）; 散射光接收器（20），其在照射浮动粒子（50）时产生的散射光中选择性地接收预定偏振分量的光，并产生第二检测信号; 以及基于第一检测信号和第二检测信号来识别浮动粒子的类型的识别处理器（30）。 入射到背部监视器的受光元件（12）的入射光包括：背面监视用激光束（L0）; 以及在散射光（Ls）中向激光照射器（10）行进的反向散射光（Lbs）。

公开(公告)号：US20160298956A1

公开(公告)日：2016-10-13

申请号：US15093749

申请日：2016-04-08

Applicant: Taiwan Biophotonic Corporation

Inventor： YU-TANG LI ,  CHANG-SHENG CHU ,  PEI-CHENG HO ,  KUAN-JUI HO ,  SHUANG-CHAO CHUNG ,  CHIH-HSUN FAN ,  JYH-CHERN CHEN

IPC: G01B11/27 ,  G01N33/483 ,  A61B5/1455

CPC classification number: G01N21/21 ,  A61B3/10 ,  A61B3/152 ,  A61B5/1455 ,  G01B11/272 ,  G01N33/483 ,  G01N2201/0633 ,  G01N2201/0683 ,  G01N2201/126

Abstract: The present disclosure generally relates to a device and a method for alignment. The alignment device provides optical architecture to align the alignment device to an analyte and measure the optical properties of an analyte. The method for alignment provides steps for aligning an optical measurement device to an analyte.

Abstract translation: 本公开一般涉及一种用于对准的装置和方法。 对准装置提供光学架构以将对准装置对准分析物并测量分析物的光学性质。 对准方法提供了将光学测量装置与分析物对准的步骤。

公开(公告)号：US20160285223A1

公开(公告)日：2016-09-29

申请号：US15176346

申请日：2016-06-08

Applicant: KLA-Tencor Corporation

Inventor： Yung-Ho Chuang ,  J. Joseph Armstrong ,  Justin Dianhuan Liou ,  Vladimir Dribinski ,  David L. Brown

IPC: H01S3/00 ,  G01N21/95 ,  G02B5/08 ,  G01N21/21 ,  G02B27/28 ,  G02B5/30

CPC classification number: H01S3/0057 ,  G01N21/21 ,  G01N21/9501 ,  G01N2201/06113 ,  G01N2201/0683 ,  G01N2201/0697 ,  G02B5/0816 ,  G02B5/3083 ,  G02B27/281 ,  G02B27/283 ,  G02B27/286 ,  H01S3/083

Abstract: A pulse multiplier includes a polarizing beam splitter, a wave plate, and a set of multi-surface reflecting components (e.g., one or more etalons and one or more mirrors). The polarizing beam splitter passes input laser pulses through the wave plate to the multi-surface reflecting components, which reflect portions of each input laser pulse back through the wave plate to the polarizing beam splitter. The polarizing beam splitter reflects each reflected portion to form an output of the pulse multiplier. The multi-surface reflecting components are configured such that the output pulses exiting the pulse multiplier have an output repetition pulse frequency rate that is at least double the input repetition pulse frequency.

Abstract translation: 脉冲倍增器包括偏振分束器，波片和一组多表面反射分量（例如，一个或多个标准具和一个或多个反射镜）。 偏振分束器将输入的激光脉冲通过波片传递到多表面反射分量，其将每个输入激光脉冲的部分反射通过波片到偏振分束器。 偏振分束器反射每个反射部分以形成脉冲乘法器的输出。 多表面反射部件被配置为使得离开脉冲乘法器的输出脉冲的输出重复脉冲频率至少是输入重复脉冲频率的两倍。

公开(公告)号：US09429508B2

公开(公告)日：2016-08-30

申请号：US14434404

申请日：2013-08-30

Applicant: SONY CORPORATION

Inventor： Taichi Takeuchi ,  Shingo Imanishi

IPC: G01N15/14 ,  G01N21/53 ,  G01N21/21 ,  G01N21/49 ,  G01N21/47 ,  G01N15/10

CPC classification number: G01N15/1436 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/21 ,  G01N21/47 ,  G01N21/49 ,  G01N21/53 ,  G01N21/645 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2021/6478 ,  G01N2201/06113 ,  G01N2201/0638 ,  G01N2201/0683

Abstract: A microparticle measuring apparatus for highly accurately detecting the position of a microparticle flowing through a flow channel includes a light irradiation unit for irradiating a microparticle flowing through a flow channel with light, and a scattered light detection unit for detecting scattered light from the microparticle, including an objective lens for collecting light from the microparticle, a light splitting element for dividing the scattered light from the light collected by the objective lens, into first and second scattered light, a first scattered light detector for receiving an S-polarized light component, and an astigmatic element disposed between the light splitting element and the first scattered light detector, and making the first scattered light astigmatic. A relationship between a length L from a rear principal point of the objective lens to a front principal point of the astigmatic element, and a focal length f of the astigmatic element satisfies the following formula I. 1.5f≦L≦2.5f  (I)

Abstract translation: 用于高精度地检测流过流路的微粒的位置的微粒测量装置包括：用于照射流过流路的微粒的光照射单元，以及用于检测来自微粒的散射光的散射光检测单元，包括 用于收集来自微粒的光的物镜，将从物镜收集的光中散射的光分成第一和第二散射光的分光元件，用于接收S偏振光分量的第一散射光检测器，以及 设置在所述分光元件和所述第一散射光检测器之间的散光元件，以及使所述第一散射光散光。 从物镜的后方主点到散光元件的前方主点的长度L与散光元件的焦距f的关系满足下式I1.5f≤L≤2.5f（I）

公开(公告)号：US20160223457A1

公开(公告)日：2016-08-04

申请号：US14916538

申请日：2014-09-03

Applicant: LEICA MICROSYSTEMS CMS GMBH

Inventor： Vishnu Vardhan KRISHNAMACHARI

IPC: G01N21/21 ,  G01N21/65 ,  G02B21/00

CPC classification number: G01N21/21 ,  G01N21/65 ,  G01N2201/067 ,  G01N2201/0683 ,  G02B21/002 ,  G02B21/0032 ,  G02B21/0068 ,  G02B27/283 ,  G02B27/286

Abstract: The invention relates to a method for investigating a sample, the sample being impinged upon by illuminating light, and detected light emerging from the sample being directed to a detector, and the illuminating light being directed through an acousto-optic component with which the impingement upon the sample by illuminating light can be temporarily interrupted. The method is notable for the fact that the sample is illuminated with a first illuminating light bundle that has a first linear polarization direction, and with a second illuminating light bundle whose linear polarization direction is continuously switched over between the first linear polarization direction and a second linear polarization direction different from the first linear polarization direction, the illuminating light having the first linear polarization direction proceeding along a first light path and illuminating light having the second linear polarization direction proceeding along a second light path, and the acousto-optic component combining the light paths.

Abstract translation: 本发明涉及一种用于研究样品的方法，通过照射光照射样品，并且检测到从样品中出射的光被引导到检测器，并且照明光被引导通过声光部件，撞击在其上 可以暂时中断通过照明光的样品。 该方法值得注意的是，样品被具有第一线偏振方向的第一照明光束照射，并且第二照明光束的线偏振方向在第一线偏振方向和第二线偏振方向之间连续切换 线偏振方向与第一线偏振方向不同的是，具有第一线偏振方向的照明光沿第一光路行进，具有第二线偏振方向的照明光沿第二光路行进，声光分量合成 光路。