Abstract:
A semiconductor device used for fluorescent-based molecule detection and a method for manufacturing the same are provided. The semiconductor device has a fluid channel layer defining a fluid channel through which a sample stream flows. A target cell coupled with a fluorescent source is contained by the sample stream. The semiconductor device also has an excitation light source for generating excitation light that reaches the target cell coupled with the fluorescent source to generate fluorescent light. The semiconductor device also has a light filter layer for permitting the fluorescent light to pass through and to block the excitation light and a light detection layer for detecting the fluorescent light. The functional components of the device are highly integrated. Leakage of the excitation light and background noise into the light detection component can be minimized to improve the quality of detection.
Abstract:
Optical microresonator platforms are provided comprising a substrate having a surface, a plurality of SiO2 pillars, and a plurality of SiO2 whispering gallery mode (WGM) optical microresonators, each SiO2 pillar extending from the surface of the substrate and terminating in a corresponding SiO2 WGM optical microresonator of the plurality of SiO2 WGM optical microresonators, wherein the substrate, the plurality of SiO2 pillars and the plurality of SiO2 WGM optical microresonators form a monolithic structure, and further wherein the substrate is substantially transparent to visible light. The substrate may be a SiO2 substrate and the SiO2 WGM optical microresonator may be a SiO2 optical microtoroid.
Abstract:
A fluorescence detection system is provided. The fluorescence detection system includes a light source adapted to emit excitation light; a sample unit in which a sample is disposed; a first optical fiber adapted to connect the light source to the sample unit; an avalanche photodiode array detector adapted to receive fluorescent light generated by the sample when the sample is irradiated with the excitation light; and a second optical fiber adapted to connect the sample unit to the avalanche photodiode array detector, wherein the second optical fiber has a numerical aperture of equal to or greater than about 0.15 and the second optical fiber is positioned such that a longitudinal axis of the second optical fiber is orthogonal to a longitudinal axis of the first optical fiber. A method for detecting fluorescence and a computer-implemented method for detecting fluorescence are also provided.
Abstract:
Simultaneous Multiple Sample Light Scattering systems and methods can be used for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces, among others, that create a polymer stress response used to characterize the polymer solution and stability.
Abstract:
An apparatus for obtaining information regarding a biological structure(s) can include, for example a light guiding arrangement which can include a fiber through which an electromagnetic radiation(s) can be propagated, where the electromagnetic radiation can be provided to or from the structure. An at least partially reflective arrangement can have multiple surfaces, where the reflecting arrangement can be situated with respect to the optical arrangement such that the surfaces thereof each can receive a(s) beam of the electromagnetic radiations instantaneously, and a receiving arrangement(s) which can be configured to receive the reflected radiation from the surfaces which include speckle patterns.
Abstract:
The present concept is a method of preparing an egg to determine the color of the egg using an egg yolk cover. The egg yolk cover is dome-shaped with a base edge and inspection area. The egg yolk cover eliminates ambient light from impinging on the egg yolk and is used in combination with a light sensor to determine the color of egg yolks. The light sensor includes a single flat printed circuit board with a top and bottom side which includes at least one LED light and one color sensor, at least one light pipe receiving light from the LED and transmitting it onto a substrate at an angle theta and a tube frame including an optical tube for receiving light reflections from the substrate. The light pipes and the tube frame are compression fit between the printed circuit board and a lower housing. To determine the color of the egg yolk, the egg is first cracked onto a flat surface. The egg yolk cover is then placed over the egg yolk and the color sensor is placed onto the inspection area to measure the color.
Abstract:
According to one aspect, the invention relates to a device (100) for remote polarimetric characterisation of a sample (S). It comprises a source (10) for emitting at least one incident light wave at at least one first wavelength (λE); a monomode optical fibre (30) in which the incident light wave is intended to propagate; a polarisation state generator (PSG) arranged on the proximal side of the optical fibre; a reflector (40) intended to be arranged on the distal side of the optical fibre; a polarisation state analyser (PSA) arranged on the proximal side of the optical fibre and allowing, for each probe state of the incident wave generated by the polarisation state generator, the polarisation of the light wave obtained after propagation of the incident wave in the optical fibre (30), reflection from the distal side of the optical fibre and reverse propagation in the optical fibre (30), to be analysed. Processing means (70) make it possible to determine, from a first polarimetric characterisation of the optical fibre, a Mueller matrix (MF) associated with the optical fibre, and, from a second polarimetric characterisation of the assembly comprising the optical fibre and the sample, a Mueller matrix (MT) associated with said assembly. The Mueller matrix (Mo) associated with the sample is determined from the Mueller matrices associated with the optical fibre and the assembly comprising the optical fibre and the sample, respectively.
Abstract:
A method for producing a multilayer tissue phantom involves successively forming at least two layers, each layer formed by depositing a viscous flowable material over a supporting element or over a previously formed layer of the phantom supported by the supporting element, selectively redistributing the material while material is solidifying to control a thickness distribution of the layer, and allowing the material to solidify sufficiently to apply a next layer. The supporting element supports the material in 2 or 3 directions and effectively molds a lumen of the tissue. The neighboring layers are of different composition and of chosen thickness to provide desired optical properties and mechanical properties of the phantom. The phantom may have selected attenuation and backscattering properties to mimic tissues for optical coherence tomography imaging.
Abstract:
An optical analysis tool includes an integrated computational element (ICE). The ICE includes a first hollow-core fiber. The first hollow-core fiber has a structure configured such that a spectrum of light guided by the first hollow-core fiber is related, over a wavelength range, to a characteristic of the sample.
Abstract:
The present description relates to a remote connection system suitable for being incorporated in an aircraft (1A, 1B, 1C) comprising at least one engine propeller (50A, 50B, 50C) having a plurality of blades (52A, 52B, 52C) suitable for rotating relative to a stationary module (10A, 10B, 10C) of the aircraft about an engine axis (X). The remote connection system comprises: a light emitter device configured, when the remote connection system is incorporated in the aircraft (1A, 1B, 1C), to emit a light beam that emerges to the outside of the propeller (50A, 50B, 50C), from at least one emission surface (54A, 54B, 54C) of said propeller (50A, 50B, 50C).