公开(公告)号：US20040203136A1

公开(公告)日：2004-10-14

申请号：US10746821

申请日：2003-12-24

Applicant: Tecan Trading AG

Inventor： Gregory Kellogg ,  Timothy Johnson ,  Eric Schilling

IPC: C12M001/34

CPC classification number: G01N21/07 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01F2215/0431 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/50273 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2300/0806 ,  B01L2400/0406 ,  B01L2400/0409 ,  Y10T436/111666 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. These assays may be performed for a variety of purposes, including but not limited to screening of drug candidate compounds, life sciences research, and clinical and molecular diagnostics. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.

Abstract translation: 本发明涉及用于进行微量分析和微合成分析和方法的方法和装置。 本发明提供一种用于操纵平台的微系统平台和显微操纵装置，所述平台利用由平台旋转产生的向心力，以激励通过微通道的流体运动。 这些测定可以用于多种目的，包括但不限于候选化合物的筛选，生命科学研究以及临床和分子诊断。 提供了用于执行各种微分析或微合成方法中的任何一种的本发明装置的特异性方法。

公开(公告)号：US20040124265A1

公开(公告)日：2004-07-01

申请号：US10466764

申请日：2004-01-09

Inventor： German Kaelberer

IPC: A61M011/06

CPC classification number: B05B7/0012 ,  B01F3/04049 ,  B01F15/00123 ,  B01F15/00162 ,  B01F15/00344 ,  B01F15/0201 ,  B01F15/0261 ,  B05B1/265 ,  B05B7/0408 ,  B05B7/0416 ,  B05B7/12 ,  B23Q11/1046 ,  B23Q11/1061 ,  F16N7/32 ,  Y02P70/169

Abstract: The present invention relates to an aerosol-producing device (1) comprising an injector device (5) in which an aerosol (2) is produced from a carrier gas and a liquid. The carrier gas and the liquid are each supplied in controlled quantities to the injector device (5) via at least one throttle (8, 9) of a throttle system.

Abstract translation: 气雾剂生产装置技术领域本发明涉及一种气溶胶产生装置（1），其包括喷射器装置（5），其中气雾剂（2）由载气和液体产生。 载气和液体分别通过节气门系统的至少一个节气门（8,9）以受控的量供给到喷射器装置（5）。

公开(公告)号：US20040115097A1

公开(公告)日：2004-06-17

申请号：US10474420

申请日：2003-10-09

Inventor： Achim Wixforth ,  Christoph Gauer

IPC: G01N001/10

CPC classification number: G01N29/222 ,  B01F11/0266 ,  B01F11/0283 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0263 ,  B01F2215/0037 ,  B01L3/502792 ,  B01L2300/0816 ,  B01L2300/089 ,  B01L2400/0433 ,  B01L2400/0436 ,  B01L2400/0496 ,  G01N1/40 ,  Y10T436/25 ,  Y10T436/2575

Abstract: The invention relates to a mixing method for mixing at least one small quantity of liquid, in which a quantity of liquid is applied in a reaction region and at least one surface sound wave is reacted with the quantity of liquid. The invention relates further to a mixing device for mixing at least one quantity of liquid for performing the method of the present invention, a use of the device, and a method of analysis for bond strengths on surfaces.

Abstract translation: 本发明涉及一种用于混合至少一种少量液体的混合方法，其中在反应区域中施加一定量的液体，并且至少一个表面声波与液体量反应。 本发明还涉及用于混合至少一种量的用于实施本发明的方法的液体的混合装置，该装置的使用以及对表面上的结合强度进行分析的方法。

公开(公告)号：US20040105813A1

公开(公告)日：2004-06-03

申请号：US10723667

申请日：2003-11-26

Inventor： Kurt M. Vanden Bussche ,  Suheil F. Abdo ,  Anil R. Oroskar

IPC: C01B015/01

CPC classification number: B01J10/007 ,  B01F5/0057 ,  B01F15/0201 ,  B01J19/002 ,  B01J2219/00013 ,  B01J2219/00263 ,  B01J2219/00889 ,  C01B15/029 ,  C07D223/10 ,  C07D301/12 ,  C07D313/04 ,  Y02P20/582 ,  Y02P30/42

Abstract: A novel process for continuously mixing and reacting at least two fluids are disclosed. Excellent mixing and superior pressure drop characteristics are achieved using cyclone mixing where at least two supply channels feed a mixing chamber to create a vortex of the fluids to be mixed. The alignment of the supply channels is such that fluids are introduced into the chamber at both tangential and radial directions. In the case of gas/liquid mixing, particularly advantageous is the injection of the liquid stream tangentially and the gas stream radially. Reaction of the fluids can take place within the mixing chamber or in a separate reactor in fluid communication with the mixing chamber outlet. The process is especially useful for reacting potentially explosive mixtures of reactants where a homogeneous reactor feed mixture is critical to maintaining a non-explosive environment.

公开(公告)号：US20040091406A1

公开(公告)日：2004-05-13

申请号：US10312285

申请日：2002-12-20

Inventor： Andreas Wolfert ,  Ulrich Penzel

IPC: B01F005/04

CPC classification number: B01F5/0403 ,  B01F5/0413 ,  B01F15/0201 ,  B01F2013/1091 ,  B01F2215/0049

Abstract: In a process for mixing reactant streams (1, 2; 5) to produce a product stream (10) using a mixing configuration (15, 16) having a number of reactant feed points, an excess component stream of one reactant is divided into two reactant substreams (1, 2) and fed into the suction region (3, 4) of a mixing space (12) at right angles to a deficient component (5) entering the mixing space (12).

Abstract translation: 在使用具有多个反应物进料点的混合构型（15,16））混合反应物流（1,2; 5）以产生产物流（10）的方法中，将一种反应物的过量组分流分成两部分 反应物液流（1,2），并且进入与进入混合空间（12）的不足组分（5）成直角的混合空间（12）的抽吸区域（3,4）。

公开(公告)号：US06706519B1

公开(公告)日：2004-03-16

申请号：US09602394

申请日：2000-06-22

Applicant: Gregory J. Kellogg ,  Charles Able ,  Todd Arnold ,  Bruce L. Carvalho ,  Hsin-Chiang Lin ,  Stephen Kieffer-Higgins ,  Norman F. Sheppard ,  Mikayla Kob ,  Shari Ommert

Inventor： Gregory J. Kellogg ,  Charles Able ,  Todd Arnold ,  Bruce L. Carvalho ,  Hsin-Chiang Lin ,  Stephen Kieffer-Higgins ,  Norman F. Sheppard ,  Mikayla Kob ,  Shari Ommert

IPC: C12M134

CPC classification number: B01F13/0064 ,  B01F13/0094 ,  B01F15/0201 ,  B01F15/0233 ,  B01F2215/0431 ,  B01F2215/0477 ,  B01L3/50273 ,  B01L2200/0621 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2300/1827 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N21/4795 ,  G01N35/00069 ,  G01N2035/00237

Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The invention specifically provides devices and methods for performing miniaturized in vitro amplification assays such as the polymerase chain reaction. Methods specific for the apparatus of the invention for performing PCR are provided.

Abstract translation: 本发明涉及用于进行微量分析和微合成分析和方法的方法和装置。 本发明提供一种用于操纵平台的微系统平台和显微操纵装置，所述平台利用由平台旋转产生的向心力，以激励通过微通道的流体运动。 本发明特别提供了用于进行小型化的体外扩增测定（例如聚合酶链式反应）的装置和方法。 提供了用于进行PCR的本发明装置专用的方法。

公开(公告)号：US20040047778A1

公开(公告)日：2004-03-11

申请号：US10466683

申请日：2003-07-21

Inventor： Felix Wolf ,  Christian Backer ,  Sybille Miklos ,  Christine Sallinger ,  Marcus Neumuller ,  Stefan Kunz ,  Martin Wegner ,  Florian Metz ,  Bernd Mittmann ,  Johann Sperl ,  Thomas Kerscher ,  Josef Amann

IPC: F28D001/00

CPC classification number: F23D11/103 ,  B01F5/0403 ,  B01F5/0415 ,  B01F5/0451 ,  B01F5/061 ,  B01F15/0201 ,  B01F2005/0448 ,  B01J19/006 ,  B01J19/26 ,  B01J2219/00119 ,  B01J2219/00768 ,  C01B3/36 ,  C01B3/363 ,  C01B2203/0255 ,  F23C5/02 ,  F23C7/004 ,  F23D11/108 ,  F23D11/14 ,  F23D11/38 ,  F23D11/383 ,  F23D11/40 ,  F23D2207/00 ,  F23D2212/10 ,  F23D2213/00 ,  F23D2900/00016 ,  F23M5/025 ,  H01M8/0612

Abstract: A system for converting fuel and air into reformate with a reformer which has a reaction space, a nozzle for supplying a fuel/air mixture to the reaction space, and a fuel feed for supplying fuel to the nozzle. In the reaction space, there is a breaker body for a fuel/air mixture supplied through the nozzle.

Abstract translation: 一种用具有反应空间的重整器将燃料和空气转化为重整产物的系统，用于向反应空间供应燃料/空气混合物的喷嘴和用于向喷嘴供应燃料的燃料供给系统。 在反应空间中，存在用于通过喷嘴供应的燃料/空气混合物的破碎机主体。

公开(公告)号：US20030128626A1

公开(公告)日：2003-07-10

申请号：US10300186

申请日：2002-11-20

Inventor： Udo Hendrick Verkerk

IPC: B01F013/08 ,  B01F015/06

CPC classification number: B01F13/0818 ,  B01F13/0827 ,  B01F15/0201 ,  B01F15/0224 ,  B01F15/0231 ,  B01F15/066 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00288 ,  B01J2219/00337 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00414 ,  B01J2219/00418 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00599 ,  B01J2219/00601 ,  B01J2219/00684 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01L3/0293 ,  C40B30/08 ,  C40B40/18 ,  C40B50/08 ,  C40B60/14

Abstract: An apparatus for the addition of a compound or compound mixture to another which includes a primary vessel adapted having at least one receptacle adapted to contain at least one primary substance. At least one secondary vessel is provided. Each secondary vessel is adapted to contain at least one secondary substance. Each secondary vessel is movably mounted within the primary vessel for movement between a stored position and at least one mixing position,. In the stored position, a peripheral edge of each secondary vessel is above a level of the at least one primary substance. In each mixing position the peripheral edge of the secondary vessel is moved below the level of the at least one receptacle containing the at least one primary substance, thereby permitting the at least one primary substance to overflow the peripheral edge into the secondary vessel with the at least one secondary substance.

Abstract translation: 一种用于将化合物或化合物混合物添加到另一种的装置，其包括适于具有至少一个适于容纳至少一种主要物质的容器的主容器。 提供至少一个次级容器。 每个次级容器适于容纳至少一种次级物质。 每个次级容器可移动地安装在主容器内，用于在存储位置和至少一个混合位置之间移动。 在存储位置中，每个次级容器的外围边缘高于至少一种主要物质的水平面。 在每个混合位置中，次级容器的周边边缘移动到至少一个容纳至少一个主要物质的容器的水平面以下，从而允许至少一个主要物质将周边边缘溢出到第二容器中，其中， 至少一种次要物质。

公开(公告)号：US20030081495A1

公开(公告)日：2003-05-01

申请号：US10265120

申请日：2002-10-07

Inventor： James Joseph O'Callaghan

IPC: B01F015/02

CPC classification number: B65G53/58 ,  B01F3/18 ,  B01F5/0268 ,  B01F5/10 ,  B01F5/24 ,  B01F11/0074 ,  B01F13/0227 ,  B01F15/0201 ,  B01F15/0202 ,  B01F15/024 ,  B29B7/32 ,  B65G53/14 ,  G01G13/24

Abstract: The invention relates to a material transfer device (1), in particular for use with blenders associated with a material processing device such as a plastics extruding device. The material transfer device (1) can be used for controlling delivery of measured amounts of particulate material to or from a weigh hopper, or for mixing materials in a mixing chamber of the blender. The material transfer device (1) includes a pipe (2) defining a material delivery path. The pipe (2) has a material inlet (4) and a material outlet (5). An air inlet manifold (10) encircling the pipe (2) is connected by an air supply line (14) to a pressurised air supply. Air outlets (12) of the manifold (10) direct an air stream towards the outlet (5) of the pipe (2) to draw material through the pipe (2) from a hopper (6) of particulate material (7), the pipe inlet (4) being located within the hopper (6). An air inlet valve (16) in the air supply line (14) is connected to a controller (22) which is operable to open an shut the valve (16) for pulsing the gas steam to control the amount of material delivered through the pipe (2).

Abstract translation: 本发明涉及一种材料转移装置（1），特别是用于与诸如塑料挤出装置的材料加工装置相关联的搅拌机。 材料转移装置（1）可以用于控制向称重料斗或从称重料斗输送测量量的颗粒材料，或用于将混合物料混合在搅拌机的混合室中。 材料输送装置（1）包括限定材料输送路径的管道（2）。 管（2）具有材料入口（4）和材料出口（5）。 围绕管道（2）的进气歧管（10）通过供气管线（14）连接到加压空气源。 歧管（10）的空气出口（12）将空气流引导到管道（2）的出口（5），以从颗粒材料（7）的料斗（6）将材料从管道（2）中拉出， 管道入口（4）位于料斗（6）内。 空气供应管线（14）中的进气阀（16）连接到控制器（22），控制器（22）可操作以打开关闭阀（16），用于脉冲气体蒸汽以控制通过管道输送的材料的量 （2）。

公开(公告)号：US06523992B1

公开(公告)日：2003-02-25

申请号：US09709499

申请日：2000-11-13

Applicant: Alexander Bublewitz ,  Matthias Suchan

Inventor： Alexander Bublewitz ,  Matthias Suchan

IPC: B01F504

CPC classification number: B01F15/0201 ,  A61C5/64 ,  A61C9/0026 ,  B01F3/10 ,  B01F7/00633 ,  B01F13/002 ,  B01F2013/1091 ,  B01F2215/0027 ,  B01F2215/0039 ,  B05C17/00516

Abstract: The device for mixing two pasty substances, particularly for mixing a dental impression substance with a catalyst substance, comprises a housing with a substantially tubular portion. At least two inlet openings (68) for the two pasty substances are arranged at the rear end of said housing, and an outlet opening for the mixed pasty substances is arranged at the front end of said housing. The housing comprises a coupling portion joining the tubular portion and having two coupling openings for connecting the housing with two outlet openings of a device for dispensing the two pasty substances. The coupling openings are connected to the inlet openings (68) via first and second channels (64,66) extending through the coupling portion. At least one mixer element is arranged within the tubular portion of the housing for mixing the two pasty substances when the substances are passing through the tubular portion of the housing. The first channel (64) or the second channel (66) or both channels (64,66) extend to at least two inlet openings (68). All inlet openings (68) are spatially separated from each other. The first channel(s) (64) is (are) separated from the second channel(s) (66).

Abstract translation: 用于混合两种糊状物质的装置，特别是用于将牙印模物质与催化剂物质混合的装置包括具有基本管状部分的壳体。 用于两个糊状物质的至少两个入口开口（68）布置在所述壳体的后端，并且用于混合糊状物质的出口开口布置在所述壳体的前端。 壳体包括联接部分，其连接管状部分并具有用于将壳体与用于分配两种糊状物质的装置的两个出口开口连接的两个联接开口。 联接开口通过延伸穿过联接部分的第一和第二通道（64,66）连接到入口开口（68）。 至少一个混合器元件布置在壳体的管状部分内，用于当物质通过壳体的管状部分时混合两种糊状物质。 第一通道（64）或第二通道（66）或两个通道（64,66）延伸到至少两个入口开口（68）。 所有入口开口（68）在空间上彼此分离。 第一通道（64）与第二通道（66）分离。