公开(公告)号：US06564087B1

公开(公告)日：2003-05-13

申请号：US09359574

申请日：1999-07-22

Applicant: Constantinos Pitris ,  Stephen A. Boppart ,  Xingde Li ,  Mark Brezinski ,  Eric Swanson ,  Edward McNamara ,  James G. Fujimoto

Inventor： Constantinos Pitris ,  Stephen A. Boppart ,  Xingde Li ,  Mark Brezinski ,  Eric Swanson ,  Edward McNamara ,  James G. Fujimoto

IPC: A61B500

CPC classification number: A61B5/6852 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/1005 ,  A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/445 ,  A61B5/6848 ,  A61B2562/0242 ,  A61B2562/028 ,  B82Y15/00 ,  G01B9/0205 ,  G01B9/02091 ,  G01B11/00 ,  G01B11/026 ,  G01B11/12 ,  G01B11/2441 ,  G01B2290/65 ,  G01J1/00 ,  G01N21/4795 ,  G02B5/1828 ,  G11B7/0037 ,  G11B7/005 ,  G11B7/08564 ,  G11B7/0908 ,  G11B7/0945 ,  G11B7/126 ,  G11B7/127 ,  G11B7/128 ,  G11B7/1353 ,  G11B7/14 ,  G11B7/24 ,  G11B2007/0013 ,  H01S5/141

Abstract: A fiber optic needle probe for measuring or imaging the internal structure of a specimen includes a needle defining a bore, an optical fiber substantially positioned within the bore, and a beam director in optical communication with the optical fiber. At least a portion of the wall of the needle is capable of transmitting light. The beam director directs light from the optical fiber to an internal structure being imaged and receives light from the structure through a transparent portion of the wall. An actuating device causes motion of any, or all of, the needle, optical fiber, and beam director to scan the internal structure of the specimen. The fiber optic needle probe allows imaging inside a solid tissue or organ without intraluminal insertion. When used in conjunction with an OCT imaging system, the fiber optic needle probe enables tomographic imaging of the microstructure of internal organs and tissues which were previously impossible to image in a living subject.

Abstract translation: 用于测量或成像试样的内部结构的光纤针头探针包括限定孔的针，基本上位于孔内的光纤，以及与光纤光学通信的光束指向器。 针的壁的至少一部分能够透光。 光束指示器将光从光纤引导到被成像的内部结构，并且通过壁的透明部分接收来自结构的光。 致动装置导致针，光纤和光束导向器中的任何一个或全部的运动扫描样本的内部结构。 光纤针头探针允许在没有腔内插入的情况下在固体组织或器官内进行成像。 当与OCT成像系统结合使用时，光纤针头探针能够对以前不可能在活体中形成的内部器官和组织的微结构进行层析成像。

公开(公告)号：US06282011B1

公开(公告)日：2001-08-28

申请号：US09603806

申请日：2000-06-26

Applicant: Guillermo Tearney ,  Brett E. Bouma ,  James G. Fujimoto

Inventor： Guillermo Tearney ,  Brett E. Bouma ,  James G. Fujimoto

IPC: G02F111

CPC classification number: B82Y15/00 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/1005 ,  A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/441 ,  A61B5/6852 ,  A61B2562/0242 ,  G01B9/02002 ,  G01B9/02091 ,  G01B11/00 ,  G01B11/002 ,  G01B11/026 ,  G01B11/12 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/35 ,  G01J1/00 ,  G01N21/4795 ,  G02B5/1828 ,  G02B26/06 ,  G02B27/4233 ,  G02B27/4244 ,  G02B27/4255 ,  G11B7/005 ,  G11B7/08564 ,  G11B7/127 ,  G11B7/1353 ,  G11B7/24 ,  G11B2007/0013 ,  H01S5/141

Abstract: An apparatus for performing high speed scanning of an optical delay and its application for performing optical interferometry, ranging, and imaging, including cross sectional imaging using optical coherence tomography, is disclosed. The apparatus achieves optical delay scanning by using diffractive optical elements in conjunction with imaging optics. In one embodiment a diffraction grating disperses an optical beam into different spectral frequency or wavelength components which are collimated by a lens. A mirror is placed one focal length away from the lens and the alteration of the grating groove density, the grating input angle, the grating output angle, and/or the mirror tilt produce a change in optical group and phase delay. This apparatus permits the optical group and phase delay to be scanned by scanning the angle of the mirror. In other embodiments, this device permits optical delay scanning without the use of moving parts.

公开(公告)号：US6111645A

公开(公告)日：2000-08-29

申请号：US79687

申请日：1998-05-15

Applicant: Guillermo Tearney ,  Brett E. Bouma ,  James G. Fujimoto

Inventor： Guillermo Tearney ,  Brett E. Bouma ,  James G. Fujimoto

IPC: A61B3/10 ,  A61B3/12 ,  A61B5/00 ,  A61B5/103 ,  G01B9/02 ,  G01B11/00 ,  G01B11/02 ,  G01B11/12 ,  G01B11/24 ,  G01J1/00 ,  G01N21/47 ,  G02B5/18 ,  G02B27/44 ,  G11B7/00 ,  G11B7/005 ,  G11B7/085 ,  G11B7/125 ,  G11B7/135 ,  G11B7/24 ,  H01S5/14

CPC classification number: B82Y15/00 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/1225 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/6852 ,  G01B11/00 ,  G01B11/002 ,  G01B11/026 ,  G01B11/12 ,  G01B11/2441 ,  G01B9/02002 ,  G01B9/02091 ,  G01J1/00 ,  G01N21/4795 ,  G02B26/06 ,  G02B27/4233 ,  G02B27/4244 ,  G02B27/4255 ,  G02B5/1828 ,  G11B7/005 ,  G11B7/08564 ,  G11B7/127 ,  G11B7/1353 ,  A61B1/00096 ,  A61B2562/0242 ,  A61B5/0084 ,  A61B5/441 ,  G01B2290/20 ,  G01B2290/35 ,  G11B2007/0013 ,  G11B7/24 ,  H01S5/141

Abstract: An apparatus for performing high speed scanning of an optical delay and its application for performing optical interferometry, ranging, and imaging, including cross sectional imaging using optical coherence tomography, is disclosed. The apparatus achieves optical delay scanning by using diffractive optical elements in conjunction with imaging optics. In one embodiment a diffraction grating disperses an optical beam into different spectral frequency or wavelength components which are collimated by a lens. A mirror is placed one focal length away from the lens and the alteration of the grating groove density, the grating input angle, the grating output angle, and/or the mirror tilt produce a change in optical group and phase delay. This apparatus permits the optical group and phase delay to be scanned by scanning the angle of the mirror. In other embodiments, this device permits optical delay scanning without the use of moving parts.

Abstract translation: 公开了一种用于执行光学延迟的高速扫描的装置及其用于执行光学干涉测量，测距和成像的应用，包括使用光学相干断层摄影的横截面成像。 该装置通过使用衍射光学元件结合成像光学器件实现光学延迟扫描。 在一个实施例中，衍射光栅将光束分散成由透镜准直的不同光谱频率或波长分量。 镜子放置一个远离镜头的焦距，并且光栅槽密度，光栅输入角度，光栅输出角度和/或镜面倾斜度的变化产生光学组和相位延迟的变化。 该装置允许通过扫描反射镜的角度来扫描光学组和相位延迟。 在其他实施例中，该装置允许光学延迟扫描而不使用移动部件。

公开(公告)号：US5905268A

公开(公告)日：1999-05-18

申请号：US844741

申请日：1997-04-21

Applicant: Gustavo Garcia ,  John T. Duerr

Inventor： Gustavo Garcia ,  John T. Duerr

IPC: G01J1/00 ,  G01J3/10

CPC classification number: G01J1/00 ,  G01J3/10

Abstract: An inspection lamp for detection of a fluorescent material which absorbs electromagnetic energy in a specific excitation frequency band and which emits electromagnetic energy in a specific fluorescent emission frequency band within the visible light spectrum. The lamp includes a bulb housing, a light source within the bulb housing, and a dichroic filter. The dichroic filter is adapted to transmit electromagnetic radiation in the excitation frequency band of the fluorescent material and reflect electromagnetic radiation in the fluorescent emission frequency band of the material.

Abstract translation: 一种用于检测吸收特定激发频带中的电磁能并在可见光谱内以特定荧光发射频带发射电磁能的荧光材料的检查灯。 该灯包括灯泡外壳，灯泡外壳内的光源和二向色滤光片。 二向色滤光片适用于在荧光材料的激发频带中传输电磁辐射，并反射材料的荧光发射频带中的电磁辐射。

公开(公告)号：US4454658A

公开(公告)日：1984-06-19

申请号：US300966

申请日：1981-09-10

Applicant: Donald F. Lewis, deceased ,  by Sheri Lewis, administrator

Inventor： Donald F. Lewis, deceased ,  by Sheri Lewis, administrator

IPC: G01J1/00 ,  G01W1/12 ,  G01C1/00

CPC classification number: G01W1/12 ,  G01J1/00

Abstract: A device to locate the position of a communication satellite with respect to a specific site on the earth's surface including a transparent screen having markings to indicate the positions of one or more satellites for that site with respect to a horizontal platform and a north orientation, a table including an arcuate means to mount the screen, a wide-angle viewer fixed to the table with its axis perpendicular to the tangent of the arcuate means at its south position, a compass fixed to the table oriented with north-south parallel to the axis of the wide-angle viewer and a level to indicate when the tabletop is horizontal.

Abstract translation: 一种用于定位通信卫星相对于地球表面上的特定位置的位置的装置，包括具有标记的透明屏幕，用于指示相对于水平平台和北方向的该位置的一个或多个卫星的位置， 桌子包括安装屏幕的弧形装置，固定在桌子上的广角观察器，其轴线垂直于其南部位置的弧形装置的切线，固定在桌子上的罗盘，其平行于南北向 的广角观看者和一个水平来指示桌面何时是水平的。

公开(公告)号：US4177566A

公开(公告)日：1979-12-11

申请号：US862778

申请日：1977-12-21

Applicant: Bernard M. Haines

Inventor： Bernard M. Haines

IPC: G01J1/00 ,  G01W1/12 ,  G01C1/00

CPC classification number: G01W1/12 ,  G01J1/00

Abstract: An insolation survey device for determining the exposure of a reference point to a cyclically varying radiation source. The device employs a base member for horizontally supporting a display sheet premarked with a grid calibrated in units corresponding to the measurement being taken. A transparent reflective member is supported by the base member over the display sheet so that a reflected view of the surrounding appurtenances and the view of the display sheet, through the transparent dome, form one composite picture. In the composite picture so formed, the period or periods, if any, within the radiation cycle that the reference point will be exposed to said radiation appear as unobstructed sky superimposed onto the premarked grid. A compass is provided to directionally align the device and means are provided for orienting the base member in a true horizontal plane.

Abstract translation: 用于确定参考点暴露于循环变化的辐射源的日照测量装置。 该装置采用水平支撑显示板的基座部件，该显示板预先标有以所采取的测量为单位校准的网格。 透明反射构件由显示板上的基座构件支撑，使得周围的附属物的反射视图和通过透明圆顶的显示片的视图形成一个复合图像。 在如此形成的复合图像中，参考点将暴露于所述辐射的辐射循环内的周期或周期（如果有的话）显示为叠加在预先标记的网格上的无障碍天空。 设置指南针以定向对准装置，并且提供用于使基部构件在真实水平面中定向的装置。

公开(公告)号：US3582210A

公开(公告)日：1971-06-01

申请号：US3582210D

申请日：1968-12-10

Applicant: JACK D JONES

Inventor： JONES JACK D

IPC: G01J1/00 ,  G01J1/42 ,  G07C3/00 ,  G01N21/00

CPC classification number: G01J1/00 ,  G01J1/42 ,  G07C3/00

Abstract: An illumination plotter for plotting illumination characteristics of thoroughfare lighting systems including a vehicle, an adjustable length, horizontally extending, supporting bar mounted on the top of said vehicle, and a pair of light intensity sensing devices mounted on opposite ends of the supporting bar. The sensing devices are connected to an amplifier carried in the vehicle, and the amplifier is connected to a recording system. The sensing devices each have convex, upwardly facing light-sensitive surfaces to obtain maximum exposure to light emanating from above.

公开(公告)号：US20240361456A1

公开(公告)日：2024-10-31

申请号：US18764268

申请日：2024-07-04

Applicant: OPSYS Tech Ltd.

Inventor： Mark J. Donovan

IPC: G01S17/10 ,  G01J1/00 ,  G01S7/48 ,  G01S7/481 ,  G01S7/487 ,  G01S17/89 ,  G01S17/931 ,  G01W1/02

CPC classification number: G01S17/10 ,  G01J1/00 ,  G01S7/4808 ,  G01S7/4814 ,  G01S7/4817 ,  G01S7/4876 ,  G01S17/89 ,  G01S17/931 ,  G01W1/02

Abstract: A method of Light Detection and Ranging (LIDAR) includes generating a first optical pulse that propagates towards a target and receiving an optical return signal reflected from the target resulting from the generated first optical pulse. The optical return signal is processed to determine a number of additional optical pulses desired to be propagated towards the target to meet a performance criteria. The determined number of additional optical pulses is then generated and propagated towards the target. The additional optical return signals reflected from the target are received and processed to obtain one or more LIDAR measurements.

公开(公告)号：US20190194765A1

公开(公告)日：2019-06-27

申请号：US16287275

申请日：2019-02-27

Applicant: GeneWeave Biosciences, Inc.

Inventor： Diego Ariel REY ,  Shaunak ROY ,  Leonardo Maestri TEIXEIRA ,  Ryan C. GRISWOLD ,  Kenneth G. OLSON ,  Bruce J. RICHARDSON ,  Victor H. YEE ,  Werner FREI

IPC: C12Q1/6897 ,  B01L3/00 ,  G01N21/13 ,  B01L7/00 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01N21/76 ,  G01N21/03 ,  G01N21/01 ,  G01J1/00

CPC classification number: C12Q1/6897 ,  B01L3/502 ,  B01L3/50825 ,  B01L3/52 ,  B01L3/523 ,  B01L3/54 ,  B01L3/545 ,  B01L7/00 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/042 ,  B01L2300/047 ,  B01L2300/049 ,  B01L2300/0672 ,  B01L2400/0478 ,  B01L2400/06 ,  B01L2400/0683 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01J1/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/13 ,  G01N21/76 ,  G01N21/763 ,  G01N2035/00346 ,  G01N2035/0405 ,  G01N2333/195

Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.

公开(公告)号：US20180240318A1

公开(公告)日：2018-08-23

申请号：US15435689

申请日：2017-02-17

Applicant: CEJAY ENGINEERING, LLC

Inventor： Derek HAYNES ,  Guido Albert LEMKE ,  Mark HAYNES

IPC: G08B21/02

CPC classification number: G01J1/00 ,  H04W84/20

Abstract: A beacon device for control by a beacon controller external to the beacon device. The beacon device includes a beacon emitter configured to emit beacon signals, a microcontroller coupled to control the beacon emitter, and a communication module coupled to the microcontroller and configured to transfer signals between the beacon device and the beacon controller.