HIGHLY-INTEGRATED ULTRAHIGH-RESOLUTION MID-INFRARED DUAL-COMB SPECTROSCOPY MEASUREMENT DEVICE AND METHOD

    公开(公告)号:US20220113191A1

    公开(公告)日:2022-04-14

    申请号:US17352327

    申请日:2021-06-20

    Abstract: An ultrahigh-resolution mid-infrared (MIR) dual-comb spectroscopy (DCS) measurement device includes a pump unit, a microring resonator (MRR) unit, a modulation unit, a splitting unit, a testing unit, a signal detection unit, a power balance unit, a reference detection unit and a spectral analysis unit. The measurement method includes: adjusting the laser emitted by the pump unit to the MRR unit; adjusting the modulation unit and performing dual-frequency modulation; generating two sets of MIR optical frequency combs (OFCs) with different repetition rates and splitting the MIR OFCs into the test light and the reference light; performing photoelectric conversion on the test light and injecting the test light to the spectral analysis unit; performing photoelectric conversion on the reference light and injecting the reference light to the spectral analysis unit; and performing Fourier transformation and data processing on test results to obtain absorption spectrum of the to-be-tested sample.

    TIME-RESOLVED SINGLE-PHOTON COUNTING APPARATUS

    公开(公告)号:US20220113189A1

    公开(公告)日:2022-04-14

    申请号:US17428435

    申请日:2020-01-20

    Inventor: Sucbei MOON

    Abstract: The present invention provides a time-resolved single-photon counting apparatus, including an excitation light source for generating pulsed excitation light, a specimen optics for collecting an optical signal caused by irradiating the pulsed excitation light to a specimen, a photoelectric converter for photoelectrically converting the optical signal to generate an analog single-photon signal, an analog-to-digital (AD) signal converter for sampling the analog single-photon signal to convert the same into a digital single-photon signal, a digital photon-discrimination and timing detector for generating a photon-discrimination signal by discriminating the single-photon property of the digital single-photon signal to count a pulse time point of the digital single-photon signal to generate a delay time signal having delay time information, and a time-signal processor for counting valid single-photon detection events according to the delay time with reference to the photon-discrimination signal.

    Native fluorescence detection methods, devices, and systems for organic compounds

    公开(公告)号:US11262301B1

    公开(公告)日:2022-03-01

    申请号:US17013469

    申请日:2020-09-04

    Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.

    NON-LIVING SURROGATE INDICATORS AND METHODS FOR SANITATION VALIDATION

    公开(公告)号:US20220018836A1

    公开(公告)日:2022-01-20

    申请号:US17344202

    申请日:2021-06-10

    Abstract: Systems, surrogates, indicators and methods for rapid assessment of sanitation processes are provided. Non-living and non-toxic surrogates applied to a platform or encapsulated in a biological material mounted to a platform are exposed to a sanitation process to be evaluated. Responses to sanitation are measured and quantified using FTIR and chemometrics including principal component analysis (PCA), partial least squares regression (PLSR), loading plots and predictive models. An artificial leaf platform with one or more types of surrogates on one surface and an anchor such as an adhesive film on a second surface is described. Surrogate types include nucleic acid, phage, yeast and algae surrogates. Surrogates may also be attached directly or through a polymer to the platform surface. Surrogates may also be encapsulated or attached to the outside of a biological carrier such as a yeast cell that is free or coupled to the platform.

    Multichromatic calibration method and device

    公开(公告)号:US11226232B2

    公开(公告)日:2022-01-18

    申请号:US16651060

    申请日:2018-09-26

    Abstract: A Multichromatic Calibration (MC) method of at least a spectral sensor which is one of a list comprising at least a spectrometer, a multispectral sensor, a hyperspectral sensor, a spectral camera, a color camera. The method comprises a. generating a plurality of different multichromatic spectra, wherein i. a spectrum from the plurality of different multichromatic spectra contains light intensity measurable by the at least one spectral sensor and by a reference spectral device, and ii. a spectrum from the plurality of different multichromatic spectra contains light centered around at least two different wavelengths and is configured to be integrated during an exposure time of a single measurement from any of the at least one spectral sensor or the reference spectral device; b. measuring each multichromatic spectrum of the plurality of different multichromatic spectra with the reference spectral device and the at least one spectral sensor; and from all data of the measured multichromatic spectra, compute a transfer function which relates a response of the at least one spectral sensor to a corresponding response of the reference spectral device, without measuring the spectral response of the at least one spectral sensor.

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