公开(公告)号：US20170198131A1

公开(公告)日：2017-07-13

申请号：US15314268

申请日：2015-05-28

Applicant: KURARAY CO., LTD.

Inventor： Yosuke JOGO ,  Chie SUZUKI

IPC: C08L51/00 ,  C08K5/134 ,  C08K5/3435 ,  C08K5/13 ,  C08K5/3475 ,  C08F257/02 ,  C08K5/1575

CPC classification number: C08L51/003 ,  C08F257/02 ,  C08F297/046 ,  C08J3/124 ,  C08J2353/02 ,  C08K5/005 ,  C08K5/13 ,  C08K5/134 ,  C08K5/1575 ,  C08K5/3435 ,  C08K5/3475 ,  C08K2201/013 ,  C08L53/025 ,  C08L2205/025 ,  C08L53/02

Abstract: Provided are a thermoplastic elastomer composition containing 100 parts by mass of (a) a specified hydrogenated block copolymer and 0.01 to 5 parts by mass of (b) at least one additive selected from an antioxidant and a light stabilizer, wherein the additive (b) is soluble in toluene at room temperature, and the additive (b) exists in the inside and on the surface of the pellet; and a molded article formed from the pellet.

公开(公告)号：US20160280863A1

公开(公告)日：2016-09-29

申请号：US15073042

申请日：2016-03-17

Applicant: Zimmer, Inc.

Inventor： Dirk Pletcher

IPC: C08J3/20 ,  C08J3/28 ,  B05D3/06 ,  A61L27/16 ,  A61L27/50 ,  C08J3/24 ,  C08K5/529

CPC classification number: C08J3/203 ,  A61L27/16 ,  A61L27/505 ,  A61L2430/02 ,  B05D3/068 ,  B29C71/02 ,  B29C71/04 ,  B29C2035/0877 ,  B29K2023/0683 ,  C08J3/24 ,  C08J3/28 ,  C08J7/065 ,  C08J7/08 ,  C08J7/123 ,  C08J2323/04 ,  C08J2323/06 ,  C08K5/005 ,  C08K5/1545 ,  C08K5/529 ,  C08K2201/013 ,  C08L23/06

Abstract: Various embodiments disclosed relate to melt-stabilized ultra high molecular weight antioxidant, methods of making the same, and medical implants made from the same. In various embodiments, the present invention provides a method of melt-stabilizing ultra high molecular weight polyethylene (UHMWPE). The method can include coating a solid material including LIMA/PE with an antioxidant, to provide an antioxidant-coated solid material. The method can include pre-irradiatively heating the antioxidant-coated solid material to diffuse the antioxidant therein, to provide an antioxidant-diffused solid material. The method can include irradiating the antioxidant-diffused solid material, to provide an irradiated solid material. The method can include post-irradiatively heating the irradiated solid material, the heating sufficient to melt at least part of the UHMWPE, to provide a heated material. The method can also include solidifying the heated material, to provide a melt-stabilized material.

Abstract translation: 所公开的各种实施方案涉及熔融稳定的超高分子量抗氧化剂，其制备方法和由其制备的医用植入物。 在各种实施方案中，本发明提供了一种熔融稳定超高分子量聚乙烯（UHMWPE）的方法。 该方法可以包括用抗氧化剂涂覆包括LIMA / PE的固体材料，以提供抗氧化剂涂覆的固体材料。 该方法可以包括预先加热抗氧化剂涂覆的固体材料以使其中的抗氧化剂扩散，以提供抗氧化剂扩散的固体材料。 该方法可以包括照射抗氧化剂扩散的固体材料，以提供照射的固体材料。 该方法可以包括对辐射的固体材料进行后照射加热，足以熔化至少部分UHMWPE的加热，以提供加热的材料。 该方法还可以包括固化加热的材料，以提供熔融稳定的材料。

公开(公告)号：US09220689B2

公开(公告)日：2015-12-29

申请号：US14052283

申请日：2013-10-11

Applicant: DSM IP ASSETS B.V.

Inventor： Steven Armes ,  Jian-Jun Yuan

IPC: A61K9/51 ,  B82Y30/00 ,  A61K9/50 ,  C08K3/36 ,  C08K9/00 ,  C09D7/12 ,  G02B1/111 ,  C08K9/02 ,  C08L53/00

CPC classification number: A61K9/5089 ,  A61K9/501 ,  C08K3/36 ,  C08K9/00 ,  C08K9/02 ,  C08K9/10 ,  C08K9/12 ,  C08K2201/011 ,  C08K2201/013 ,  C08L53/00 ,  C08L2207/53 ,  C09D7/70 ,  G02B1/111 ,  Y10T428/254 ,  Y10T428/2998

Abstract: Methods for the preparation of polymer-templated core-shell nanoparticles include the steps of (a) preparing a cationic polymeric core material comprising polymeric micelles, and (b) coating the core material with a silica-comprising shell by depositing the shell onto the polymeric micelles from at least one silica precursor to form the core-shell nanoparticles. Compositions which include the core-shell nanoparticles are adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.

Abstract translation: 制备聚合物模板核 - 壳纳米颗粒的方法包括以下步骤：（a）制备包含聚合物胶束的阳离子聚合物芯材料，和（b）通过将壳体沉积到聚合物上涂覆含有二氧化硅的壳体， 从至少一个二氧化硅前体的胶束形成核 - 壳纳米颗粒。 包括核 - 壳纳米颗粒的组合物适于促进响应于系统的pH的受控变化而将至少一种活性剂控制递送到系统中。

公开(公告)号：US20150044449A1

公开(公告)日：2015-02-12

申请号：US14457546

申请日：2014-08-12

Applicant: PurThread Technologies, Inc.

Inventor： Stephen W. Foss ,  Stanley Chamberlain ,  Lloyd Frick

IPC: C08K3/22 ,  B05D1/00 ,  D01G13/00 ,  C08K3/30

CPC classification number: C08K3/22 ,  A01N25/10 ,  A01N59/20 ,  C08J3/128 ,  C08J3/203 ,  C08J2367/02 ,  C08J2377/02 ,  C08J2377/06 ,  C08K3/30 ,  C08K2003/2241 ,  C08K2003/3045 ,  C08K2201/013 ,  D01D1/00 ,  D01F1/04 ,  D01F1/06 ,  D01F1/103 ,  D01F6/60 ,  D01F6/62 ,  D01G13/00 ,  D10B2331/04 ,  Y10T428/249921 ,  A01N59/16

Abstract: High-melting antimicrobial polymer fibers and antimicrobial fabrics comprising such fibers are prepared by preparing a masterbatch of polymer pellets (e.g., PET), silver and copper salts, and a compounding agent which provides free flowing polymer pellets which can be prepared in advance, with a long shelf life. Polymer masterbatches prepared by the methods of the invention can produce limited color or off-white antimicrobial fibers and fabrics using conventional melt spinning manufacturing methods. Fabrics incorporating fibers of the present invention are potent inhibitors of Athlete's foot fungi, gram negative and gram positive bacteria, and drug resistant pathogens.

Abstract translation: 包含这种纤维的高熔点抗菌聚合物纤维和抗微生物织物通过制备聚合物颗粒（例如PET），银和铜盐的母料和提供可预先制备的自由流动的聚合物颗粒的配混剂来制备， 保质期长。 通过本发明的方法制备的聚合物母料可以使用常规的熔融纺丝制造方法产生有限的颜色或非白色抗微生物纤维和织物。 结合本发明的纤维的织物是运动员足部真菌，革兰氏阴性和革兰氏阳性菌以及耐药性病原体的有效抑制剂。

公开(公告)号：US20130210134A1

公开(公告)日：2013-08-15

申请号：US13848917

申请日：2013-03-22

Applicant: Kaohsiung Medical University

Inventor： Li-Fang Wang ,  Shuo-Li Sun ,  Yu-Lun Lo

IPC: C12N15/85

CPC classification number: A61K48/0025 ,  A61K48/0033 ,  A61K48/0041 ,  B82Y5/00 ,  B82Y30/00 ,  C08K9/04 ,  C08K9/08 ,  C08K2201/005 ,  C08K2201/01 ,  C08K2201/013 ,  C12N15/85

Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

Abstract translation: 公开了纳米颗粒及其制备方法，其制备方法包括将聚乙烯亚胺（PEI）与聚（丙烯酸）键合的氧化铁（PAAIO）混合以形成PEI-PAAIO聚电解质络合物（PEC）和混合 PEI-PAAIO PEC与遗传物质如质粒DNA形成PEI-PAAIO / pDNA磁性纳米颗粒。 PEI-PAAIO / pDNA磁复合物具有高水分散性，适合长期保存，显示出超顺磁性，低细胞毒性，高稳定性和良好的转染效率，因此PEI-PAAIO PEC可代替PEI作为非病毒基因载体。

公开(公告)号：US08450389B1

公开(公告)日：2013-05-28

申请号：US12752688

申请日：2010-04-01

Applicant: Quint Barefoot

Inventor： Quint Barefoot

IPC: C08K3/16 ,  C08K3/36

CPC classification number: A62D3/33 ,  A61L2/23 ,  B01J20/28016 ,  B09B3/00 ,  C08K2201/013

Abstract: The invention includes a system for solidification of liquid medical waste for use in connection with a vessel configured to receive an aqueous liquid to be solidified. The system includes an absorbent composition including a plurality of surface cross-linked superabsorbent particles and a plurality of second particles. Additionally, a soluble packet may be included so that the absorbent composition is released upon dissolution of the packet. The invention also includes a liquid solidification system for reducing gel block and a method of solidifying liquid medical waste.

Abstract translation: 本发明包括用于与配置成接收待固化的水性液体的容器结合使用的液体医疗废物的固化系统。 该系统包括吸收组合物，其包括多个表面交联的超吸收颗粒和多个第二颗粒。 此外，可以包括可溶性包装，使得吸收性组合物在包装溶解时释放。 本发明还包括用于还原凝胶块的液体凝固系统和固化液体医疗废物的方法。

公开(公告)号：US20120157626A1

公开(公告)日：2012-06-21

申请号：US13074491

申请日：2011-03-29

Applicant: Li-Fang Wang ,  Shuo-Li Sun ,  Yu-Lun Lo

Inventor： Li-Fang Wang ,  Shuo-Li Sun ,  Yu-Lun Lo

IPC: C08G63/91 ,  B82Y30/00

CPC classification number: A61K48/0025 ,  A61K48/0033 ,  A61K48/0041 ,  B82Y5/00 ,  B82Y30/00 ,  C08K9/04 ,  C08K9/08 ,  C08K2201/005 ,  C08K2201/01 ,  C08K2201/013 ,  C12N15/85

Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

Abstract translation: 公开了纳米颗粒及其制备方法，其制备方法包括将聚乙烯亚胺（PEI）与聚（丙烯酸）键合的氧化铁（PAAIO）混合以形成PEI-PAAIO聚电解质络合物（PEC）和混合 PEI-PAAIO PEC与遗传物质如质粒DNA形成PEI-PAAIO / pDNA磁性纳米颗粒。 PEI-PAAIO / pDNA磁复合物具有高水分散性，适合长期保存，显示出超顺磁性，低细胞毒性，高稳定性和良好的转染效率，因此PEI-PAAIO PEC可代替PEI作为非病毒基因载体。

公开(公告)号：US07723422B2

公开(公告)日：2010-05-25

申请号：US11317614

申请日：2005-12-23

Applicant: Michele L. Zoromski ,  Liliana L. Atanasoska ,  Robert W. Warner

Inventor： Michele L. Zoromski ,  Liliana L. Atanasoska ,  Robert W. Warner

IPC: C08K3/40

CPC classification number: A61L31/128 ,  A61L27/446 ,  A61L29/126 ,  C08K9/02 ,  C08K9/04 ,  C08K2201/013 ,  C08L53/00

Abstract: Reinforced copolymers formed from a functionalized copolymer that undergoes a reactive extrusion process with an inorganic component to form the reinforced copolymer. The functionalized copolymer in the form of a block and/or graft copolymer includes hard segments and soft segments, where the soft segments are covalently bonded with a coupling agent either before or after copolymerization with the hard segments. The reinforced copolymer of the present disclosure can be suitable for use as a biomaterial and/or in medical devices.

Abstract translation: 由官能化共聚物形成的增强共聚物，其经历与无机组分的反应性挤出方法以形成增强共聚物。 嵌段和/或接枝共聚物形式的官能化共聚物包括硬链段和软链段，其中软链段在与硬链段共聚合之前或之后与偶联剂共价键合。 本公开的增强共聚物可适用于生物材料和/或医疗装置。

公开(公告)号：US20080306202A1

公开(公告)日：2008-12-11

申请号：US11760354

申请日：2007-06-08

Applicant: Liang-Bih Lin ,  Daniel Levy ,  Jin Wu

Inventor： Liang-Bih Lin ,  Daniel Levy ,  Jin Wu

IPC: C08K3/04 ,  C08K3/22 ,  C08K3/10 ,  G03G15/16

CPC classification number: C08K9/04 ,  C08K9/08 ,  C08K2201/013 ,  G03G15/162

Abstract: Exemplary embodiments provide intermediate transfer members that can be used in electrostatographic devices and methods for using them in forming an image. The disclosed intermediate transfer members can include a plurality of nanotubes with high electrical conductivity, high thermal conductivity, and/or low humidity sensitivity. The hydrophobicity of the nanotubes can be controlled by covalently grafting hydrophobic components onto one or more nanotubes; surface treating one or more nanotubes; and encapsulating one or more nanotubes with hydrophobic components. In an exemplary embodiment, the nanotubes can be dispersed in polymer matrices and/or formed on the surface of polymer matrices of the intermediate transfer members. The intermediate transfer members can take various forms of belts, sheets, webs, films, rolls, tubes or any shape that can provide a smooth surface and rotatable function.

Abstract translation: 示例性实施例提供可用于静电摄影装置的中间转印构件以及用于形成图像的方法。 所公开的中间转印部件可以包括具有高导电性，高导热性和/或低湿度敏感性的多个纳米管。 纳米管的疏水性可通过将疏水组分共价接枝到一个或多个纳米管上来控制; 表面处理一个或多个纳米管; 并用疏水组分封装一个或多个纳米管。 在示例性实施方案中，纳米管可以分散在聚合物基质中和/或形成在中间转移构件的聚合物基质的表面上。 中间转印构件可以采用各种形式的带，片，幅，膜，辊，管或可以提供光滑表面和可旋转功能的任何形状。

公开(公告)号：US20080008875A1

公开(公告)日：2008-01-10

申请号：US11718878

申请日：2004-11-11

Applicant: Sang Oh Han

Inventor： Sang Oh Han

IPC: C08J5/18 ,  B43K19/00 ,  C08K3/00

CPC classification number: B43K31/00 ,  C08K2201/013 ,  Y10T428/264

Abstract: A nontoxic micro anti-bacterial film coated with silver nano-particles and a method of manufacturing the same are disclosed. The method of manufacturing a non-toxic micro anti-bacterial film coated with silver nano-particles including the steps of: producing mixed/combined powers as anti-bacterial powders, thermosensitive or photosensitive ink capsule powers, and fragrant capsule powders, and silver nano powder are combined with an additive; producing solid powders as 20-50 weight % of the mixed/combined powders, and 50-80 weight % of olefin, acrylic or urethane binder are mixed and then disperse; producing a paste type of print ink as 30 weight % of the solid powders and 70 weight % of solvent are mixed; and printing the print ink on a thin film made of olefin resin, acrylic resin, and urethane resin, using a silk screen printing method, printing a predetermined design thereon. The designs of the non-toxic micro anti-bacterial film can be pressed and transferred to the stationery products or the necessaries of life. Therefore, users can obtain joy and interest from the products as designs are changed according to temperature change. Also, the non-toxic micro anti-bacterial film exhales fragrance and has anti-bacterial operation.

Abstract translation: 公开了涂覆有银纳米颗粒的无毒微细抗菌薄膜及其制造方法。 制造涂覆有银纳米颗粒的无毒微细抗菌薄膜的方法，包括以下步骤：产生作为抗菌粉末，热敏或感光油墨胶囊功能的混合/组合功能，以及芳香胶囊粉末和银纳米颗粒 粉末与添加剂组合; 生产固体粉末为20-50重量％的混合/组合粉末，和50-80重量％的烯烃，丙烯酸或氨基甲酸酯粘合剂混合，然后分散; 混合30重量％固体粉末和70重量％溶剂的糊状印刷油墨， 并使用丝网印刷方法将印刷油墨印刷在由烯烃树脂，丙烯酸树脂和聚氨酯树脂制成的薄膜上，在其上印刷预定的设计。 无毒微生物抗菌膜的设计可以压制并转移到文具产品或生活必需品上。 因此，随着设计根据温度变化而改变，用户可以获得产品的喜悦和兴趣。 另外，无毒的微细抗菌薄膜呼出香味，并具有抗菌作用。