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公开(公告)号：US20210178423A1
公开(公告)日：2021-06-17
申请号：US17123390
申请日：2020-12-16
Applicant: Covalon Technologies Inc.
Inventor： Mirzo Kanoatov , Genevieve Conant , Darryl Knight , Daryl Sivakumaran
Abstract: A reactor for coating a device is provided. The reactor comprises a hollow body and a port. The hollow body is for supporting the device. The port is in fluid communication with the hollow body for exchanging a coating fluid. In use, the device is moveable within the hollow body from a stacked orientation to an unstacked orientation. Processes for coating devices and systems thereof are also provided.
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公开(公告)号：US12180386B2
公开(公告)日：2024-12-31
申请号：US16900332
申请日：2020-06-12
Applicant: Covalon Technologies Inc.
Inventor： Vyacheslav Dudnyk , Valerio DiTizio
IPC: C09D175/04 , A61L29/04 , A61L29/08 , A61L29/16
Abstract: Provided herein is a method of grafting a polymeric coating onto a first side of a wall of a device. The method comprises: applying an initiator substantially only to a second side of the wall; applying a coating composition to the first side of the wall; and graft-polymerizing the coating composition.
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公开(公告)号：US20160263270A1
公开(公告)日：2016-09-15
申请号：US15065610
申请日：2016-03-09
Applicant: Covalon Technologies Inc.
Inventor： JOHN RICHARD HANDS , Valerio DITIZIO
CPC classification number: A61L15/58 , A61L15/46 , A61L2300/104 , A61L2300/206 , A61L2430/38 , C08L83/04
Abstract: There is provided a method for reducing microbial load at a site on the skin of a subject. The method comprises applying a dressing over the site on the skin of the subject at which a medical procedure that involves breaching the skin is to be performed. As used in the method, the dressing comprises a self-adhesive silicone gel sheet comprising at least about 95 wt % silicone and up to about 5 wt % of particulates of an antimicrobial dispersed in the silicone. The dressing is applied with the silicone gel sheet contacting the skin of the subject and is left in place to allow the antimicrobial to diffuse onto the site.
Abstract translation: 提供了减少受试者皮肤部位的微生物负荷的方法。 所述方法包括在所述受试者的皮肤上施用敷料以进行涉及破坏皮肤的医疗过程。 如在该方法中所使用的，该敷料包括自粘性硅胶片，其包含至少约95重量％的硅氧烷和至多约5重量％的分散在硅氧烷中的抗微生物颗粒。 施用敷料与硅胶凝胶片接触受试者的皮肤并保留在适当位置以允许抗微生物剂扩散到部位上。
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公开(公告)号：US20230241282A1
公开(公告)日：2023-08-03
申请号：US18075283
申请日：2022-12-05
Applicant: COVALON TECHNOLOGIES INC.
Inventor： Vyacheslav DUDNYK , Mirzo KANOATOV , Valerio DITIZIO
CPC classification number: A61L15/425 , C08J9/125 , A61L15/32 , A61L15/64 , A61L15/44 , A61L15/225 , A61L2300/418 , C08J2389/04 , C08J2203/10 , C08J2405/04 , A61L2300/404 , A61L2400/04
Abstract: Disclosed herein are matrices, compositions and methods of making matrices. The matrix comprises a biomolecule and the matrix is a dried, cross-linked foam. The matrix is not lyophilized. The method comprises foaming the composition, crosslinking the composition and drying the composition. Matrices disclosed herein are useful as wound dressings and treating wounds.
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公开(公告)号：US11517644B2
公开(公告)日：2022-12-06
申请号：US16671975
申请日：2019-11-01
Applicant: COVALON TECHNOLOGIES INC.
Inventor： Vyacheslav Dudnyk , Mirzo Kanoatov , Valerio Ditizio
Abstract: Disclosed herein are matrices, compositions and methods of making matrices. The matrix comprises a biomolecule and the matrix is a dried, cross-linked foam. The matrix is not lyophilized. The method comprises foaming the composition, crosslinking the composition and drying the composition. Matrices disclosed herein are useful as wound dressings and treating wounds.
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Patent Agency Ranking
公开(公告)号：US08628800B2
公开(公告)日：2014-01-14
申请号：US13750872
申请日：2013-01-25
Applicant: Covalon Technologies, Inc.
Inventor： Valerio DiTizio , Frank DiCosmo , Yuehua Xiao
IPC: A61K9/70
CPC classification number: A61K47/42 , A61K9/7007 , A61K47/10 , A61K47/36 , A61L15/225 , A61L15/325 , A61L15/425 , A61L31/041 , A61L31/045 , A61L31/146 , C08L5/00 , C08L5/04 , C08L5/08 , C08L71/00 , C08L89/00 , C08L89/06 , C08L2205/02 , C08L2666/26 , C08L2666/14 , C08L2666/02
Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.
Abstract translation: 本发明是基本上不粘的弹性明胶基体。 基质既不与伤口，组织和器官粘合，也具有弹性，使其柔韧。 基质是蛋白质，聚合物，交联剂和任选的增塑剂的冻干混合物。 本发明还提供了制造非粘性弹性明胶基质的方法。
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公开(公告)号：US20130137780A1
公开(公告)日：2013-05-30
申请号：US13750872
申请日：2013-01-25
Applicant: COVALON TECHNOLOGIES, INC.
Inventor： Valerio DiTizio , Frank DiCosmo , Yuehua Xiao
IPC: A61K47/42
CPC classification number: A61K47/42 , A61K9/7007 , A61K47/10 , A61K47/36 , A61L15/225 , A61L15/325 , A61L15/425 , A61L31/041 , A61L31/045 , A61L31/146 , C08L5/00 , C08L5/04 , C08L5/08 , C08L71/00 , C08L89/00 , C08L89/06 , C08L2205/02 , C08L2666/26 , C08L2666/14 , C08L2666/02
Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.
Abstract translation: 本发明是基本上不粘的弹性明胶基体。 基质既不与伤口，组织和器官粘合，也具有弹性，使其柔韧。 基质是蛋白质，聚合物，交联剂和任选的增塑剂的冻干混合物。 本发明还提供了制造非粘性弹性明胶基质的方法。
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公开(公告)号：US12151033B2
公开(公告)日：2024-11-26
申请号：US18075283
申请日：2022-12-05
Applicant: COVALON TECHNOLOGIES INC.
Inventor： Vyacheslav Dudnyk , Mirzo Kanoatov , Valerio Ditizio
Abstract: Disclosed herein are matrices, compositions and methods of making matrices. The matrix comprises a biomolecule and the matrix is a dried, cross-linked foam. The matrix is not lyophilized. The method comprises foaming the composition, crosslinking the composition and drying the composition. Matrices disclosed herein are useful as wound dressings and treating wounds.
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公开(公告)号：US11679409B2
公开(公告)日：2023-06-20
申请号：US17123390
申请日：2020-12-16
Applicant: Covalon Technologies Inc.
Inventor： Mirzo Kanoatov , Genevieve Conant , Darryl Knight , Daryl Sivakumaran
Abstract: A reactor for coating a device is provided. The reactor comprises a hollow body and a port. The hollow body is for supporting the device. The port is in fluid communication with the hollow body for exchanging a coating fluid. In use, the device is moveable within the hollow body from a stacked orientation to an unstacked orientation. Processes for coating devices and systems thereof are also provided.
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公开(公告)号：US20210299017A1
公开(公告)日：2021-09-30
申请号：US17213783
申请日：2021-03-26
Applicant: Covalon Technologies Inc.
Inventor： Valerio DiTizio , Brian Pedlar , Agnesa Shala-Lawrence , Vyacheslav Dudnyk , Genevieve Conant
Abstract: An antimicrobial composition is described herein. The composition comprises an antimicrobial agent, a sequestering agent, a release agent, and an optional dispersing agent. Hand sanitizers and sprays comprising the composition are also described, along with related methods of sanitizing items, such as hands, surfaces, and personal protective equipment.
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