-
1.发明申请公开(公告)号：US20120160708A1
公开(公告)日：2012-06-28
申请号：US12121389
申请日：2008-05-15
Applicant: Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
Inventor： Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
IPC: G01N27/26
CPC classification number: G01N27/127
Abstract: The present invention provides compositions, devices and methods for detecting esterase activity. The present invention also provides devices and methods of detecting esterase inhibitors, for example, organophosphates. In particular, the present invention provides a biosensor comprising Neuropathy Target Esterase (NTE) polypeptides. Further, the present invention relates to medicine, industrial chemistry, agriculture, and homeland security.
Abstract translation: 本发明提供了用于检测酯酶活性的组合物，装置和方法。 本发明还提供了检测酯酶抑制剂例如有机磷酸酯的装置和方法。 特别地，本发明提供了包含神经病目标酯酶（NTE）多肽的生物传感器。 此外，本发明涉及医药，工业化学，农业和国土安全。
-
2.发明授权Electrobiocatalytic reactors having reversible bioelectronic interfaces and methods and devices related thereto 有权具有可逆生物电子界面的电化学反应器和与其相关的方法和装置公开(公告)号：US09406959B2
公开(公告)日：2016-08-02
申请号：US12766169
申请日：2010-04-23
Applicant: Robert Mark Worden , Brian L Hassler , Lawrence T. Drzal , Ilsoon Lee
Inventor： Robert Mark Worden , Brian L Hassler , Lawrence T. Drzal , Ilsoon Lee
CPC classification number: C25B11/0489 , C12Q1/005 , C25B11/0405 , C25B11/0415 , G01N27/3272 , H01M4/9008 , H01M8/16 , Y02E60/527
Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.
Abstract translation: 可用于生物反应器，生物传感器和生物燃料电池的便宜，易于再生的生物电子装置包括导电碳电极和键合到导电碳电极表面的生物电子界面，其中生物电子界面包括直接静电结合的催化活性材料 或间接地连接到导电碳电极，以便于在pH变化时容易去除，从而允许生物电子界面的容易再生。
-
公开(公告)号：US20080014356A1
公开(公告)日：2008-01-17
申请号：US11818994
申请日：2007-06-15
Applicant: Ilsoon Lee , Troy Hendricks
Inventor： Ilsoon Lee , Troy Hendricks
IPC: B05D3/10
CPC classification number: H05K3/182 , B82Y30/00 , C23C18/1608 , C23C18/2086 , C23C18/31 , C23C18/32 , C23C18/40 , H05K2203/0108 , H05K2203/0709
Abstract: Processes for creating versatile and selective metal patterns (such as copper and nickel) combine the use of PEM coatings, microcontact printing (MCP), and electroless deposition. MCP is used to pattern a charged catalyst (such as palladium and stannous ions) onto oppositely charged PEM coated substrates. The substrate is then placed into an electroless deposition bath where a metal selectively plates at the catalyzed regions.
Abstract translation: 用于创建多功能和选择性金属图案（例如铜和镍）的工艺结合了使用PEM涂层，微接触印刷（MCP）和无电沉积。 MCP用于将带电荷的催化剂（例如钯和亚锡离子）图案化到带有相反电荷的PEM涂覆的基底上。 然后将衬底放置在无电沉积浴中，其中金属在催化区域选择性地平板化。
-
4.发明授权公开(公告)号：US09023478B2
公开(公告)日：2015-05-05
申请号：US13619696
申请日：2012-09-14
Applicant: Ilsoon Lee , Lawrence T. Drzal , Jue Lu , Troy R. Hendricks
Inventor： Ilsoon Lee , Lawrence T. Drzal , Jue Lu , Troy R. Hendricks
CPC classification number: G03F7/0002 , B82Y10/00 , B82Y40/00 , C01B32/20 , H05K1/0259 , H05K3/1275 , H05K2201/0323 , H05K2203/0108 , H05K2203/09 , H05K2203/105 , Y10T428/30
Abstract: Methods involve a combination of polyelectrolyte multilayer (PEM) coating or silane self assembly on a substrate; microcontact printing; and conductive graphite particles, especially size controlled highly conductive exfoliated graphite nanoplatelets. The conductive graphite particles are coated with a charged polymer such as sulfonated polystyrene. The graphite particles are patterned using microcontact printing and intact pattern transfer on a substrate that has an oppositely-charged surface. The method allows for conductive organic patterning on both flat and curved surfaces and can be used in microelectronic device fabrication.
Abstract translation: 方法涉及在基底上组合聚电解质多层（PEM）涂层或硅烷自组装; 微接触印刷; 和导电石墨颗粒，特别是尺寸控制的高导电性剥离石墨纳米片。 导电石墨颗粒用带电聚合物如磺化聚苯乙烯涂覆。 使用微接触印刷和在具有相反电荷的表面的基底上的完整图案转印来对石墨颗粒进行图案化。 该方法允许在平坦和弯曲表面上的导电有机图案化，并且可以用于微电子器件制造。
-
5.发明申请公开(公告)号：US20130009825A1
公开(公告)日：2013-01-10
申请号：US13619696
申请日：2012-09-14
Applicant: Ilsoon LEE , Lawrence T. DRZAL , Jue LU , Troy R. HENDRICKS
Inventor： Ilsoon LEE , Lawrence T. DRZAL , Jue LU , Troy R. HENDRICKS
CPC classification number: G03F7/0002 , B82Y10/00 , B82Y40/00 , C01B32/20 , H05K1/0259 , H05K3/1275 , H05K2201/0323 , H05K2203/0108 , H05K2203/09 , H05K2203/105 , Y10T428/30
Abstract: Methods involve a combination of polyelectrolyte multilayer (PEM) coating or silane self assembly on a substrate; microcontact printing; and conductive graphite particles, especially size controlled highly conductive exfoliated graphite nanoplatelets. The conductive graphite particles are coated with a charged polymer such as sulfonated polystyrene. The graphite particles are patterned using microcontact printing and intact pattern transfer on a substrate that has an oppositely-charged surface. The method allows for conductive organic patterning on both flat and curved surfaces and can be used in microelectronic device fabrication.
Abstract translation: 方法涉及在基底上组合聚电解质多层（PEM）涂层或硅烷自组装; 微接触印刷; 和导电石墨颗粒，特别是尺寸控制的高导电性剥离石墨纳米片。 导电石墨颗粒用带电聚合物如磺化聚苯乙烯涂覆。 使用微接触印刷和在具有相反电荷的表面的基底上的完整图案转印来对石墨颗粒进行图案化。 该方法允许在平坦和弯曲表面上的导电有机图案化，并且可以用于微电子器件制造。
-
Patent Agency Ranking
公开(公告)号：US20100314248A1
公开(公告)日：2010-12-16
申请号：US12766169
申请日：2010-04-23
Applicant: Robert M. Worden , Brian L. Hassler , Lawrence T. Drzal , Ilsoon Lee
Inventor： Robert M. Worden , Brian L. Hassler , Lawrence T. Drzal , Ilsoon Lee
IPC: C25B11/06 , C25B11/12 , G01N27/327 , B05D1/04 , C25B9/00
CPC classification number: C25B11/0489 , C12Q1/005 , C25B11/0405 , C25B11/0415 , G01N27/3272 , H01M4/9008 , H01M8/16 , Y02E60/527
Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.
Abstract translation: 可用于生物反应器，生物传感器和生物燃料电池的便宜，易于再生的生物电子装置包括导电碳电极和键合到导电碳电极表面的生物电子界面，其中生物电子界面包括直接静电结合的催化活性材料 或间接地连接到导电碳电极，以便于在pH变化时容易去除，从而允许生物电子界面的容易再生。
-
7.发明申请公开(公告)号：US20100052995A1
公开(公告)日：2010-03-04
申请号：US12515232
申请日：2007-11-15
Applicant: Ilsoon Lee , Lawrence T. Drzal , Jue Lu , Troy R. Hendricks
Inventor： Ilsoon Lee , Lawrence T. Drzal , Jue Lu , Troy R. Hendricks
CPC classification number: G03F7/0002 , B82Y10/00 , B82Y40/00 , C01B32/20 , H05K1/0259 , H05K3/1275 , H05K2201/0323 , H05K2203/0108 , H05K2203/09 , H05K2203/105 , Y10T428/30
Abstract: Methods involve a combination of polyelectrolyte multilayer (PEM) coating or silane self assembly on a substrate; microcontact printing; and conductive graphite particles, especially size controlled highly conductive exfoliated graphite nanoplatelets. The conductive graphite particles are coated with a charged polymer such as sulfonated polystyrene. The graphite particles are patterned using microcontact printing and intact pattern transfer on a substrate that has an oppositely-charged surface. The method allows for conductive organic patterning on both flat and curved surfaces and can be used in microelectronic device fabrication.
Abstract translation: 方法涉及在基底上组合聚电解质多层（PEM）涂层或硅烷自组装; 微接触印刷; 和导电石墨颗粒，特别是尺寸控制的高导电性剥离石墨纳米片。 导电石墨颗粒用带电聚合物如磺化聚苯乙烯涂覆。 使用微接触印刷和在具有相反电荷的表面的基底上的完整图案转印来对石墨颗粒进行图案化。 该方法允许在平坦和弯曲表面上的导电有机图案化，并且可以用于微电子器件制造。
-
8.发明授权公开(公告)号：US08623196B2
公开(公告)日：2014-01-07
申请号：US12121389
申请日：2008-05-15
Applicant: Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
Inventor： Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
IPC: G01N27/327
CPC classification number: G01N27/127
Abstract: The present invention provides compositions, devices and methods for detecting esterase activity. The present invention also provides devices and methods of detecting esterase inhibitors, for example, organophosphates. In particular, the present invention provides a biosensor comprising Neuropathy Target Esterase (NTE) polypeptides. Further, the present invention relates to medicine, industrial chemistry, agriculture, and homeland security.
Abstract translation: 本发明提供了用于检测酯酶活性的组合物，装置和方法。 本发明还提供了检测酯酶抑制剂例如有机磷酸酯的装置和方法。 特别地，本发明提供了包含神经病目标酯酶（NTE）多肽的生物传感器。 此外，本发明涉及医药，工业化学，农业和国土安全。
-
公开(公告)号：US08460785B2
公开(公告)日：2013-06-11
申请号：US12515155
申请日：2007-11-15
Applicant: Ilsoon Lee , Troy R. Hendricks
Inventor： Ilsoon Lee , Troy R. Hendricks
CPC classification number: B81B3/0072 , A61K8/0208 , A61Q19/08 , B32B27/08 , B32B27/14 , B32B2307/50 , B32B2555/00 , Y10T428/24942 , Y10T428/25 , Y10T428/259 , Y10T428/31938
Abstract: Methods to control and prevent polymer films from buckling are provided. Buckled morphologies are created by thermally cycling or mechanically compressing a substrate such as poly(dimethylsiloxane) (PDMS) coated with a polyelectrolyte multilayer film. By varying the dimensions of the surface topography relative to the buckling wavelength (e.g., pattern size is less than, equal to, and greater than the buckling wavelength) the orientation and the local morphology of the buckled films is controlled. Based on the information obtained, we demonstrate how to alleviate the unavoidable buckling by incorporating nanoparticles into the film. In addition, we studied the effect of the silica layer that results from oxygen plasma treatment and the critical temperature for permanent film buckling.
Abstract translation: 提供了控制和防止聚合物膜翘曲的方法。 通过热循环或机械压缩涂覆有聚电解质多层膜的基底（例如聚（二甲基硅氧烷）（PDMS））产生弯曲的形态。 通过改变表面形貌相对于弯曲波长的尺寸（例如，图案尺寸小于，等于并且大于屈曲波长），控制屈曲膜的取向和局部形态。 基于获得的信息，我们演示如何通过将纳米颗粒纳入薄膜来缓解不可避免的屈曲。 此外，我们研究了氧等离子体处理产生的二氧化硅层的影响和永久膜屈曲的临界温度。
-
公开(公告)号：US20100143677A1
公开(公告)日：2010-06-10
申请号：US12515155
申请日：2007-11-15
Applicant: Ilsoon Lee , Troy R. Hendricks
Inventor： Ilsoon Lee , Troy R. Hendricks
CPC classification number: B81B3/0072 , A61K8/0208 , A61Q19/08 , B32B27/08 , B32B27/14 , B32B2307/50 , B32B2555/00 , Y10T428/24942 , Y10T428/25 , Y10T428/259 , Y10T428/31938
Abstract: Methods to control and prevent polymer films from buckling are provided. Buckled morphologies are created by thermally cycling or mechanically compressing a substrate such as poly(dimethylsiloxane) (PDMS) coated with a polyelectrolyte multilayer film. By varying the dimensions of the surface topography relative to the buckling wavelength (e.g., pattern size is less than, equal to, and greater than the buckling wavelength) the orientation and the local morphology of the buckled films is controlled. Based on the information obtained, we demonstrate how to alleviate the unavoidable buckling by incorporating nanoparticles into the film. In addition, we studied the effect of the silica layer that results from oxygen plasma treatment and the critical temperature for permanent film buckling.
Abstract translation: 提供了控制和防止聚合物膜翘曲的方法。 通过热循环或机械压缩涂覆有聚电解质多层膜的基底（例如聚（二甲基硅氧烷）（PDMS））产生弯曲的形态。 通过改变表面形貌相对于弯曲波长的尺寸（例如，图案尺寸小于，等于并且大于屈曲波长），控制屈曲膜的取向和局部形态。 基于获得的信息，我们演示如何通过将纳米颗粒纳入薄膜来缓解不可避免的屈曲。 此外，我们研究了氧等离子体处理产生的二氧化硅层的影响和永久膜屈曲的临界温度。
-
-
-
-
-
-
-
-
-
Search Results
17
records
(took 0.015 seconds)
