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Patent Agency Ranking
1.发明申请MICROFLUIDIC CHIPS WITH MICRO-TO-MACRO SEAL AND A METHOD OF MANUFACTURING MICROFLUIDIC CHIPS WITH MICRO-TO-MACRO SEAL 审中-公开具有微孔至密封的微流感胶囊和用微孔密封制造微流感胶囊的方法公开(公告)号：US20150086443A1
公开(公告)日：2015-03-26
申请号：US14033473
申请日：2013-09-22
Applicant: Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
Inventor： Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
CPC classification number: B01L3/502707 , B01L3/502715 , B01L2200/027 , B01L2200/0689 , B01L2300/04 , B01L2300/0816 , B01L2300/0887
Abstract: A microfluidic chip for a microfluidic system includes a micro-to-macro seal. The microfluidic chip has a substrate, at least one microfluidic pathway in the substrate, and a PDMS seal layer on the substrate and above the microfluidic pathway. The PDMS seal layer provides a seal above the microfluidic pathway and prevent particles or contaminants entering the micro-channel during transportation or prior to application. During application, a needle or piping pierces through the PDMS seal layer, and fluid can be pumped into the microfluidic chip without concern for the fluid leaking despite high pressure required to pump or drive the fluid into the microfluidic pathway.
Abstract translation: 用于微流体系统的微流控芯片包括微到宏密封。 微流控芯片具有底物，底物中的至少一个微流体途径，以及基底上的PDMS密封层和微流体途径之上的PDMS密封层。 PDMS密封层在微流体通道之上提供密封，并防止在运输过程中或施用前颗粒或污染物进入微通道。 在施加期间，针或管道穿透PDMS密封层，并且尽管泵送或驱动流体进入微流体通路所需的高压力，但流体可被泵送到微流体芯片中，而不用担心流体泄漏。
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2.发明授权Method of continuously manufacturing microfluidic chips with BoPET film for a microfluidic device and microfluidic chips with BoPET film 有权使用BoPET薄膜连续制造微流控芯片的微流控器件和具有BoPET薄膜的微流控芯片的方法公开(公告)号：US09120298B2
公开(公告)日：2015-09-01
申请号：US14028106
申请日：2013-09-16
Applicant: Tej Patel , Ryan Revilla , Matthew D'Ooge
Inventor： Tej Patel , Ryan Revilla , Matthew D'Ooge
IPC: B32B37/00 , B32B37/02 , B32B37/14 , B32B37/18 , B01L3/00 , B81C3/00 , B32B37/12 , B81B1/00 , G01N27/447 , G01N35/00
CPC classification number: B32B37/1284 , B01J2219/00783 , B01L3/502707 , B01L2200/02 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , B01L2300/16 , B32B37/02 , B32B2037/1253 , B32B2307/518 , B32B2310/0831 , B32B2310/0843 , B32B2315/08 , B32B2367/00 , B81B2201/058 , B81C1/00119 , B81C3/001 , B81C2201/019 , G01N27/44791 , G01N2035/00158
Abstract: A microfluidic chip includes a thin biaxially-oriented polyethylene terephthalate (“BoPET”) film and a micro-channel in the BoPET film. A method for manufacturing a microfluidic chip includes coating UV epoxy on a first side of a BoPET film, placing the BoPET film on a first substrate with the first side facing the first substrate, curing the UV epoxy on the first side of the BoPET film to attach the BoPET film on the first substrate; forming at least one microfluidic pathway in the BoPET film, coating UV epoxy on a first side of a second substrate, placing the second substrate on the BoPET film with the first side of the second substrate facing a second side of the BoPET film, and curing the UV epoxy on the first side of the second substrate to attach the BoPET film to the second substrate. The microfluidic chip may be a multi-layered chip.
Abstract translation: 微流控芯片包括薄双轴取向的聚对苯二甲酸乙二醇酯（“BoPET”）薄膜和BoPET薄膜中的微通道。 微流控芯片的制造方法包括在BoPET膜的第一面上涂布UV环氧树脂，将该BoPET膜放置在第一衬底上，其第一面朝向第一衬底，使BoPET膜的第一侧的UV环氧树脂固化 将BoPET膜附着在第一衬底上; 在所述BoPET膜中形成至少一个微流体通路，在第二基底的第一侧上涂覆UV环氧树脂，将所述第二基底放置在所述BoPET膜上，其中所述第二基底的第一面朝向所述BoPET膜的第二侧， 在第二衬底的第一侧上的UV环氧树脂将BoPET膜附接到第二衬底。 微流控芯片可以是多层芯片。
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3.发明授权Microfluidic chips with optically transparent glue coating and a method of manufacturing microfluidic chips with optically transparent glue coating for a microfluidic device 有权具有光学透明胶涂层的微流控芯片和用于微流体装置的光学透明胶涂层的微流控芯片的制造方法公开(公告)号：US09180652B2
公开(公告)日：2015-11-10
申请号：US14028320
申请日：2013-09-16
Applicant: Tej Patel , Ryan Revilla , Matthew D'Ooge
Inventor： Tej Patel , Ryan Revilla , Matthew D'Ooge
CPC classification number: B01L3/502707 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L3/50853 , B01L7/525 , B01L2200/027 , B01L2200/028 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0654 , B01L2300/0663 , B01L2300/0816 , B01L2300/0883 , B01L2300/0887 , B01L2300/12 , B01L2300/123 , B01L2300/168 , B01L2300/18 , B01L2300/1827 , B32B37/12 , B32B37/16 , B32B38/08 , B32B38/10 , B32B2307/202 , B32B2383/00 , B32B2457/00 , C12Q1/6806 , G01N21/0332 , G01N21/05 , G01N21/272 , G01N27/44791 , G01N2021/056 , G01N2021/058 , G01N2021/6482 , G01N2035/00158
Abstract: A microfluidic chip for a microfluidic system includes a PDMS substrate having a first thickness, at least one microfluidic pathway in the substrate, a coating along the microfluidic pathway, and a glass layer having a second thickness on the substrate and above the microfluidic pathway, wherein the coating contains an optically transparent material, and the first thickness is greater than the second thickness. The coating includes cyanoacrylates, an UV curable epoxy adhesive, a gel epoxy or epoxy under trade name of EPO-TEK OG175, MasterBond EP30LV-1 or Locite 0151.
Abstract translation: 用于微流体系统的微流体芯片包括具有第一厚度的PDMS衬底，衬底中的至少一个微流体通路，沿着微流体通路的涂层，以及在衬底上和微流体通路上方具有第二厚度的玻璃层，其中 涂层含有光学透明材料，第一厚度大于第二厚度。 涂层包括氰基丙烯酸酯，UV可固化环氧粘合剂，凝胶环氧树脂或环氧树脂，商品名为EPO-TEK OG175，MasterBond EP30LV-1或Locite 0151。
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4.发明申请MICROFLUIDIC CHIPS WITH OPTICALLY TRANSPARENT GLUE COATING AND A METHOD OF MANUFACTURING MICROFLUIDIC CHIPS WITH OPTICALLY TRANSPARENT GLUE COATING FOR A MICROFLUIDIC DEVICE 有权具有透明透明玻璃涂层的微流感胶囊和用于微流体装置的光学透明胶涂层的微流感胶囊的制造方法公开(公告)号：US20150079665A1
公开(公告)日：2015-03-19
申请号：US14028320
申请日：2013-09-16
Applicant: Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
Inventor： Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
CPC classification number: B01L3/502707 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L3/50853 , B01L7/525 , B01L2200/027 , B01L2200/028 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0654 , B01L2300/0663 , B01L2300/0816 , B01L2300/0883 , B01L2300/0887 , B01L2300/12 , B01L2300/123 , B01L2300/168 , B01L2300/18 , B01L2300/1827 , B32B37/12 , B32B37/16 , B32B38/08 , B32B38/10 , B32B2307/202 , B32B2383/00 , B32B2457/00 , C12Q1/6806 , G01N21/0332 , G01N21/05 , G01N21/272 , G01N27/44791 , G01N2021/056 , G01N2021/058 , G01N2021/6482 , G01N2035/00158
Abstract: A microfluidic chip for a microfluidic system includes a PDMS substrate having a first thickness, at least one microfluidic pathway in the substrate, a coating along the microfluidic pathway, and a glass layer having a second thickness on the substrate and above the microfluidic pathway, wherein the coating contains an optically transparent material, and the first thickness is greater than the second thickness. The coating includes cyanoacrylates, an UV curable epoxy adhesive, a gel epoxy or epoxy under trade name of EPO-TEK 0G175, MasterBond EP30LV-1 or Locite 0151.
Abstract translation: 用于微流体系统的微流体芯片包括具有第一厚度的PDMS衬底，衬底中的至少一个微流体通路，沿着微流体通路的涂层，以及在衬底上和微流体通路上方具有第二厚度的玻璃层，其中 涂层含有光学透明材料，第一厚度大于第二厚度。 涂层包括氰基丙烯酸酯，UV可固化环氧粘合剂，凝胶环氧树脂或环氧树脂，商品名为EPO-TEK 0G175，MasterBond EP30LV-1或Locite 0151。
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5.发明申请公开(公告)号：US20150078971A1
公开(公告)日：2015-03-19
申请号：US14028106
申请日：2013-09-16
Applicant: Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
Inventor： Tej PATEL , Ryan REVILLA , MATTHEW D'OOGE
CPC classification number: B32B37/1284 , B01J2219/00783 , B01L3/502707 , B01L2200/02 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , B01L2300/16 , B32B37/02 , B32B2037/1253 , B32B2307/518 , B32B2310/0831 , B32B2310/0843 , B32B2315/08 , B32B2367/00 , B81B2201/058 , B81C1/00119 , B81C3/001 , B81C2201/019 , G01N27/44791 , G01N2035/00158
Abstract: A microfluidic chip includes a thin biaxially-oriented polyethylene terephthalate (“BoPET”) film and a micro-channel in the BoPET film. A method for manufacturing a microfluidic chip includes coating UV epoxy on a first side of a BoPET film, placing the BoPET film on a first substrate with the first side facing the first substrate, curing the UV epoxy on the first side of the BoPET film to attach the BoPET film on the first substrate; forming at least one microfluidic pathway in the BoPET film, coating UV epoxy on a first side of a second substrate, placing the second substrate on the BoPET film with the first side of the second substrate facing a second side of the BoPET film, and curing the UV epoxy on the first side of the second substrate to attach the BoPET film to the second substrate. The microfluidic chip may be a multi-layered chip.
Abstract translation: 微流控芯片包括薄双轴取向的聚对苯二甲酸乙二醇酯（“BoPET”）薄膜和BoPET薄膜中的微通道。 微流控芯片的制造方法包括在BoPET膜的第一面上涂布UV环氧树脂，将该BoPET膜放置在第一衬底上，其第一面朝向第一衬底，使BoPET膜的第一面上的UV环氧树脂固化 将BoPET膜附着在第一衬底上; 在所述BoPET膜中形成至少一个微流体通路，在第二基底的第一侧上涂覆UV环氧树脂，将所述第二基底放置在所述BoPET膜上，其中所述第二基底的第一面朝向所述BoPET膜的第二侧， 在第二衬底的第一侧上的UV环氧树脂将BoPET膜附接到第二衬底。 微流控芯片可以是多层芯片。
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