中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

7 records (took 0.013 seconds)

    METHODS AND SYSTEMS FOR DETECTING AND QUANTIFYING A TARGET ANALYTE IN A SAMPLE BY NEGATIVE ION MODE MASS SPECTROMETRY
    1.
    发明申请
    METHODS AND SYSTEMS FOR DETECTING AND QUANTIFYING A TARGET ANALYTE IN A SAMPLE BY NEGATIVE ION MODE MASS SPECTROMETRY 有权

    公开(公告)号：US20230093230A1

    公开(公告)日：2023-03-23

    申请号：US17759787

    申请日：2021-01-29

    Applicant: PHYTRONIX TECHNOLOGIES INC.

    Inventor： Pierre PICARD ,  Serge AUGER

    IPC: G01N27/623 ,  G01N27/624

    Abstract: Laser diode thermal desorption coupled with tandem mass spectrometry systems and methods are described to detect at least one target analyte in a sample by negative ion mode mass spectrometry. For instance, the system and method involve desorbing a sample prepared for mass spectrometry analysis by laser diode thermal desorption to obtain a desorbed sample, and then ionizing the desorbed sample under conditions to generate an ionized analyte flow comprising a superoxide radical anion (O2.−) adduct detectable by negative ion mode mass spectrometry; and then detecting the O2.− adduct by negative ion mode mass spectrometry, to thereby detect the target analyte.

    Methods and systems for detecting and quantifying a target analyte in a sample by negative ion mode mass spectrometry
    5.
    发明授权
    Methods and systems for detecting and quantifying a target analyte in a sample by negative ion mode mass spectrometry 有权

    公开(公告)号：US12203885B2

    公开(公告)日：2025-01-21

    申请号：US17759787

    申请日：2021-01-29

    Applicant: PHYTRONIX TECHNOLOGIES INC.

    Inventor： Pierre Picard ,  Serge Auger

    IPC: G01N27/623 ,  G01N27/624

    Abstract: Laser diode thermal desorption coupled with tandem mass spectrometry systems and methods are described to detect at least one target analyte in a sample by negative ion mode mass spectrometry. For instance, the system and method involve desorbing a sample prepared for mass spectrometry analysis by laser diode thermal desorption to obtain a desorbed sample, and then ionizing the desorbed sample under conditions to generate an ionized analyte flow comprising a superoxide radical anion (O2.−) adduct detectable by negative ion mode mass spectrometry; and then detecting the O2.− adduct by negative ion mode mass spectrometry, to thereby detect the target analyte.

    METHOD FOR DETECTING BOAR TAINT
    6.
    发明申请
    METHOD FOR DETECTING BOAR TAINT 审中-公开

    公开(公告)号：US20180292375A1

    公开(公告)日：2018-10-11

    申请号：US15574316

    申请日：2017-03-02

    Applicant: PHYTRONIX TECHNOLOGIES INC.

    Inventor： Pierre PICARD ,  Serge AUGER

    IPC: G01N33/12 ,  H01J49/04

    Abstract: A method for detecting boar taint in a fat sample is provided. The method includes extracting boar taint compounds from the fat sample to obtain a boar taint extract which includes indole components and androstenone. The method also includes derivatizing the indole components such that the derivatized indole components have a lower volatility than the indole components. The method also includes desorbing the derivatized indole components and the androstenone by Laser Diode Thermal Desorption (LDTD), and ionizing the desorbed analytes. The content of boar taint compounds in the fat sample can then be determined by subjecting the ionized analytes to mass spectrometry.

    QUANTIFICATION OF AN ANALYTE IN SERUM AND OTHER BIOLOGICAL MATRICES
    7.
    发明申请
    QUANTIFICATION OF AN ANALYTE IN SERUM AND OTHER BIOLOGICAL MATRICES 有权
    分析血清和其他生物学基础的分析数据

    公开(公告)号：US20140291505A1

    公开(公告)日：2014-10-02

    申请号：US14354313

    申请日：2012-10-26

    Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD. ,  PHYTRONIX TECHNOLOGIES INC.

    Inventor： Serge Auger ,  Gregory Blachon ,  Hesham Ghobarah ,  Michael Jarvis ,  Pierre Picard

    IPC: H01J49/00 ,  H01J49/04

    CPC classification number: H01J49/0031 ,  G01N27/624 ,  G01N33/82 ,  H01J49/0431 ,  H01J49/0445 ,  H01J49/0463 ,  H01J49/168

    Abstract: Methods and systems for quantifying analytes in a biological sample are provided comprising preparing a biological sample for mass spectrometric analysis, utilizing an ionization source to ionize at least a portion of the prepared biological sample to generate an ionized analyte flow, introducing the ionized analyte flow into a differential mobility spectrometer set at a compensation voltage selected to extract ionized analyte molecules from the ionized analyte flow, introducing an output analyte flow of the differential mobility spectrometer into a mass spectrometer to detect and quantify analyte ions in the output analyte flow.

    Abstract translation: 提供了用于量化生物样品中分析物的方法和系统，包括制备用于质谱分析的生物样品，利用电离源将至少一部分制备的生物样品电离以产生电离的分析物流，将电离的分析物流引入 差示迁移率光谱仪设置在选择的电压分析物流中的离子化分析物分子的选择补偿电压，将差分迁移率光谱仪的输出分析物流引入质谱仪中，以检测和量化输出分析物流中的分析物离子。

Patent Agency Ranking