公开(公告)号：US3558600A

公开(公告)日：1971-01-26

申请号：US3558600D

申请日：1967-07-28

Applicant: ABBOTT LAB

Inventor： GEISZLER ADOLPH OSCAR ,  JONES PETER HADLEY

IPC: A61K45/00 ,  C07D243/08 ,  C07D53/02

CPC classification number: C07C305/00 ,  Y10S514/929

Abstract: NOVEL LONG CHAIN ALKYL SULFATE SALTS OF 1-(P-CHLOROBENZHYDRYL)-4-METHYLHOMOPIPERAZINE ARE DISCLOSED. THESE SALT FORMS MASK THE BITTER TASTE ASSOCIATED WITH THE FREE BASE AND SOLUBLE ACID-ADDITION SALT FORMS OF THIS COMPOUND THEREBY ENABLING THE PREPARATION OF AN ORAL DOSAGE FORM OF THIS ANTIHISTAMINIC AND BRONCHODILATING AGENT.