公开(公告)号：US3895114A

公开(公告)日：1975-07-15

申请号：US33360073

申请日：1973-02-20

Applicant: ABBOTT LAB

Inventor： JONES PETER HADLEY ,  MARTIN YVONNE CONNOLLY

IPC: A61K31/445 ,  A61K27/00

CPC classification number: A61K31/445

Abstract: Method of treating hypertension by administering to a hypertensive patient a therapeutically effective amount of a compound of the Formula

WHEREIN R1, R2, and R3 each are hydrogen, alkyl, cycloalkyl or aryl.

Abstract translation: 通过向高血压患者施用治疗有效量的式WHEREIN R1，R2和R3的化合物各自为氢，烷基，环烷基或芳基的治疗高血压的方法。

公开(公告)号：US3901926A

公开(公告)日：1975-08-26

申请号：US44203474

申请日：1974-02-13

Applicant: ABBOTT LAB

Inventor： WINN MARTIN ,  LYNN KATHLEEN RILEY ,  MARTIN YVONNE CONNOLLY

IPC: C07C37/055 ,  C07D213/30 ,  C07D213/50 ,  C07D311/80 ,  C07D311/94 ,  C07D307/83

CPC classification number: C07D213/30 ,  C07C37/055 ,  C07D213/50 ,  C07D311/80 ,  C07D311/94 ,  C07C39/367

Abstract: Alkylphenyl benzopyrans represented by the formula

WHEREIN N IS 1 OR 2; EACH R and R1 are the same or different members of the group consisting of hydrogen or loweralkyl; R2 is loweralkyl; R3 is hydrogen; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R4 and R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl and Z is C or N and the pharmaceutically acceptable salts thereof.

公开(公告)号：US3903147A

公开(公告)日：1975-09-02

申请号：US40890273

申请日：1973-10-23

Applicant: ABBOTT LAB

Inventor： KYNCL JAROSLAV ,  RILEY KATHLEEN ,  MARTIN YVONNE CONNOLLY ,  OURS CARROLL WAYNE

IPC: C07C237/00 ,  C07C103/50

CPC classification number: C07C237/00

Abstract: Covers a gamma -glutamyl amide of dopamine selected from the group consisting of

and a pharmaceutically acceptable acid addition salt thereof. Also covers the use of said gamma -glutamyl amide to increase renal blood flow by administering said amide to warm-blooded mammals.

Abstract translation: 覆盖选自HO | HO-CH 2 -CH 2 -NH 2 | PARALLEL C-CH 2 -CH 2 -CH-C-OH平行| ONH 2的多巴胺的γ-谷氨酰胺及其药学上可接受的酸加成盐。 还涵盖了通过将所述酰胺施用于温血哺乳动物来增加所述γ-谷氨酰胺以增加肾血流量的用途。