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公开(公告)号:US10215754B2
公开(公告)日:2019-02-26
申请号:US15287605
申请日:2016-10-06
Applicant: Abbott Laboratories
Inventor: Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
IPC: C07K16/20 , G01N33/569
Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
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公开(公告)号:US20150212083A1
公开(公告)日:2015-07-30
申请号:US14686351
申请日:2015-04-14
Applicant: Abbott Laboratories
Inventor: Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
IPC: G01N33/569 , C07K16/20
CPC classification number: G01N33/56905 , C07K16/20 , C07K2317/24 , C07K2317/56 , C07K2317/92 , G01N2333/44 , G01N2469/10 , G01N2469/20 , G01N2496/00
Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
Abstract translation: 本公开涉及使用试剂检测克氏锥虫的表位的试剂和方法。
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公开(公告)号:US09482667B2
公开(公告)日:2016-11-01
申请号:US14686351
申请日:2015-04-14
Applicant: Abbott Laboratories
Inventor: Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
IPC: G01N33/53 , C07K16/20 , G01N33/569
CPC classification number: G01N33/56905 , C07K16/20 , C07K2317/24 , C07K2317/56 , C07K2317/92 , G01N2333/44 , G01N2469/10 , G01N2469/20 , G01N2496/00
Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
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4.TRUNCATED HUMAN VITAMIN D BINDING PROTEIN AND MUTATION AND FUSION THEREOF AND RELATED MATERIALS AND METHODS OF USE 有权
Title translation: 截短人维生素D结合蛋白及其相关材料及其使用方法公开(公告)号:US20130295593A1
公开(公告)日:2013-11-07
申请号:US13726219
申请日:2012-12-23
Applicant: ABBOTT LABORATORIES
Inventor: Christian Beckert , Susan E. Brophy , Jonathan Grote , Dagang Huang , Jan Schultess , Bailin Tu
CPC classification number: G01N33/82 , C07K14/47 , C07K14/76 , C07K2319/00 , C07K2319/30 , C07K2319/40 , G01N33/543
Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
Abstract translation: 维生素D结合蛋白(DBP),特别是截短的DBP和突变的截短的DBP,以及其融合蛋白,编码相同的核酸分子,载体,宿主细胞和方法,试剂盒和固体支持物,用于确定总量为25 - 羟基维生素D2和25-羟基维生素D3。
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公开(公告)号:US11421023B2
公开(公告)日:2022-08-23
申请号:US16387282
申请日:2019-04-17
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: G01N33/53 , C07K16/18 , G01N33/574 , G01N33/68
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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公开(公告)号:US20170096477A1
公开(公告)日:2017-04-06
申请号:US15290762
申请日:2016-10-11
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
CPC classification number: C07K16/18 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , G01N33/57438 , G01N33/6893 , G01N2333/47 , G01N2800/085 , G01N2800/50
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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7.Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use 有权
Title translation: 截短人体维生素D结合蛋白及其突变与融合及相关材料及使用方法公开(公告)号:US08993248B2
公开(公告)日:2015-03-31
申请号:US13726219
申请日:2012-12-23
Applicant: Abbott Laboratories
Inventor: Christian Beckert , Susan E. Brophy , Jonathan Grote , Dagang Huang , Jan Schultess , Bailin Tu
IPC: C07K14/00 , C07K14/435 , G01N33/53 , G01N33/82 , C07K14/76 , C07K14/47 , G01N33/543
CPC classification number: G01N33/82 , C07K14/47 , C07K14/76 , C07K2319/00 , C07K2319/30 , C07K2319/40 , G01N33/543
Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
Abstract translation: 维生素D结合蛋白(DBP),特别是截短的DBP和突变的截短的DBP,以及其融合蛋白,编码相同的核酸分子,载体,宿主细胞和方法,试剂盒和固体支持物,用于确定总量为25 - 羟基维生素D2和25-羟基维生素D3。
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8.
公开(公告)号:US20150024457A1
公开(公告)日:2015-01-22
申请号:US14461082
申请日:2014-09-05
Applicant: ABBOTT LABORATORIES
Inventor: Susan E. Brophy , Bailin Tu , Joan D. Tyner , Dagang Huang , Robert N. Ziemann
IPC: C07K16/18
CPC classification number: C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
Abstract translation: 本发明涉及肌钙蛋白I的抗体及其使用方法。 特别地,这样的抗体可用于检测患者中的肌钙蛋白I,并且也可用于诊断例如心肌梗塞或急性冠状动脉综合征。
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公开(公告)号:US20190315844A1
公开(公告)日:2019-10-17
申请号:US16387282
申请日:2019-04-17
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: C07K16/18 , G01N33/574 , G01N33/68
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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公开(公告)号:US20170023568A1
公开(公告)日:2017-01-26
申请号:US15287605
申请日:2016-10-06
Applicant: Abbott Laboratories
Inventor: Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
IPC: G01N33/569 , C07K16/20
CPC classification number: G01N33/56905 , C07K16/20 , C07K2317/24 , C07K2317/56 , C07K2317/92 , G01N2333/44 , G01N2469/10 , G01N2469/20 , G01N2496/00
Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
Abstract translation: 本公开涉及使用试剂检测克氏锥虫的表位的试剂和方法。
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