公开(公告)号：US09285317B2

公开(公告)日：2016-03-15

申请号：US14272645

申请日：2012-11-05

Applicant: ADVANCED SENSORS LIMITED

Inventor： Khalid Thabeth ,  Stephen Taylor

IPC: G01J1/58 ,  G01N21/00 ,  G01N21/64 ,  H01J49/26 ,  H01J49/00

CPC classification number: G01N21/645 ,  G01N21/64 ,  G01N2201/06113 ,  H01J49/0009 ,  H01J49/0027 ,  H01J49/26

Abstract: An apparatus for determining the total amount of two or more substances in a liquid, at least one of said substances comprising a fluorescent substance, said apparatus comprising: a mass spectrometer device; a fluorometer device; and a processing means; wherein said mass spectrometer device is adapted to obtain a periodic measurement of the total amount of said two or more substances in the liquid, said fluorometer device being adapted to detect the fluorescent response of said at least one fluorescent substance in said liquid to an excitation signal, said processing means being programmed to determine a calibration factor by comparing a measurement obtained by the fluorometer device with said periodic measurement of the total amount of said two or more substances present obtained by the mass spectrometer device, the processing means subsequently using said calibration factor to determine measurements representative of the total amount of both fluorescent and non-fluorescent substances present in the liquid based upon the fluorescent response detected by the fluorometer device.

Abstract translation: 一种用于确定液体中两种或多种物质的总量的装置，所述物质中的至少一种包括荧光物质，所述装置包括：质谱仪装置; 荧光计装置; 和处理装置; 其中所述质谱仪装置适于获得液体中所述两种或多种物质的总量的周期性测量，所述荧光计装置适于将所述液体中所述至少一种荧光物质的荧光响应检测为激发信号 所述处理装置被编程以通过将由所述荧光计装置获得的测量值与由所述质谱仪装置获得的所述两种或多种物质的总量的所述周期性测量进行比较来确定校准因子，所述处理装置随后使用所述校准因子 基于由荧光计装置检测到的荧光响应来确定代表存在于液体中的荧光和非荧光物质的总量的测量值。