公开(公告)号：US20230356226A1

公开(公告)日：2023-11-09

申请号：US18023961

申请日：2021-07-30

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Curt A. FLORY ,  Dustin CHANG ,  Kelly KROEGER

IPC: B01L3/00

CPC classification number: B01L3/502784 ,  B01L2200/0621 ,  B01L2200/0673 ,  B01L2300/087 ,  B01L2400/0415

Abstract: A microfluidic apparatus for forming one or more droplets of an aqueous fluid suspended in a non-aqueous fluid is described. The microfluidic apparatus includes a first microfluidic channel configured for flowing an aqueous fluid through the first microfluidic channel and a second microfluidic channel fluidically connected to the first microfluidic channel and adapted to flow a non-aqueous fluid through the second microfluidic channel into the first microfluidic channel. A microfluidic reservoir fluidically connected to the first microfluidic channel and configured to receive a plurality of droplets of the first aqueous fluid. The microfluidic apparatus further includes a first electrode and a second electrode positioned such that application of voltage to the first electrode moves one or more droplets of the aqueous fluid in a first direction and application of voltage to the second electrode moves one or more droplets of the aqueous fluid in a second direction.

公开(公告)号：US20230055007A1

公开(公告)日：2023-02-23

申请号：US17975493

申请日：2022-10-27

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Tong CHEN ,  Gershon PERELMAN ,  Curt A. FLORY

IPC: H01J49/06

Abstract: An ion guide includes electrodes elongated along an axis from an entrance end to an exit end and spaced around the axis to surround an interior. The electrodes have polygonal shapes with inside surfaces disposed at a radius from the axis and having an electrode width tangential to a circle inscribed by the electrodes. An aspect ratio of the electrode width to the radius varies along the axis. The electrodes are configured to generate a two-dimensional RF electrical field in the interior having a multipole composition comprising one or more lower-order multipole components and one or more higher-order multipole components and varying along the axis in accordance with the varying aspect ratio, and having an RF voltage amplitude that varies along the axis.